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Disease Ontology (DO): familial hyperlipidemia

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Root: DO Hierarchy (disease ontology from University of Maryland)

Shortest distance to current term (+ for parents, - for children) DO term [DO ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + 4:   disease [DOID:4] <8>
+ + + 3:   disease of metabolism [DOID:0014667] <2>(22|34) (27|12|5)
+ + 2:   inherited metabolic disorder [DOID:655] <18>(12|15) (16|5|0)
+ 1:   lipid metabolism disorder [DOID:3146] <13>(3|8) (7|3|0)
0:   familial hyperlipidemia [DOID:1168] <6>(3|8) (7|3|0)
- 1:   familial hypercholesterolemia [DOID:13810] <1>(0|0) (0|0|0)
- 1:   familial combined hyperlipidemia [DOID:13809](0|0) (0|0|0)
- 1:   familial lipoprotein lipase deficiency [DOID:14118](0|0) (0|0|0)
- 1:   hyperlipoproteinemia type III [DOID:3145](0|0) (0|0|0)
- 1:   hyperlipoproteinemia type IV [DOID:1172](0|0) (0|0|0)
- 1:   hyperlipoproteinemia type V [DOID:1171](0|0) (0|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
Apolipoprotein A-I0Direct
Nuclear receptor ligand-binding domain0.0001649Direct
PGBD-like0.0005062Direct


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Family

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SCOP termFDR (all)Annotation (direct or inherited)
Apolipoprotein A-I0Direct
Long-chain cytokines0.00007288Direct
Nuclear receptor0.0001014Direct
Fatty acid binding protein-like0.0001016Direct
Nuclear receptor ligand-binding domain0.000129Direct
MMP N-terminal domain0.0003714Direct
Matrix metalloproteases, catalytic domain0.0006681Direct
Hemopexin-like domain0.0007858Direct


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Apolipoprotein A-I0Direct
Nuclear receptor ligand-binding domain0.00009848Direct
PGBD-like0.0003098Direct
Hemopexin-like domain0.0006729Direct
4-helical cytokines0.0007853Direct
Lipocalins0.000793Direct
Kringle-like0.000793Direct

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
57440,57440
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 0.00002515Direct
    57716,48508
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 48508 - Nuclear receptor ligand-binding domain
  • 0.0001477Direct
    47090,55486
  • 47090 - PGBD-like
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 0.0003098Direct


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
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