SUPERFAMILY 1.75 HMM library and genome assignments server

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Disease Ontology (DO): Graves' disease

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Root: DO Hierarchy (disease ontology from University of Maryland)

Shortest distance to current term (+ for parents, - for children) DO term [DO ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + + + 6:   disease [DOID:4] <8>
+ + + + + 5:   disease of anatomical entity [DOID:7] <12>(143|187) (147|103|58)
+ + + + 4:   immune system disease [DOID:2914] <4>(39|47) (42|27|16)
+ + + 3:   hypersensitivity reaction disease [DOID:0060056] <5>(35|46) (37|23|14)
+ + 2:   hypersensitivity reaction type II disease [DOID:417] <26>(33|43) (35|23|14)
+ 1:   autoimmune disease of endocrine system [DOID:0060005] <3>(3|4) (5|2|0)
0:   Graves' disease [DOID:12361](3|4) (5|2|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
MHC antigen-recognition domain0.00000000005062Direct
Immunoglobulin0.0000004893Direct
Bcl-2 inhibitors of programmed cell death0.000145Direct


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Family

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SCOP termFDR (all)Annotation (direct or inherited)
MHC antigen-recognition domain0.00000000007061Direct
C1 set domains (antibody constant domain-like)0.00000000007061Direct
Bcl-2 inhibitors of programmed cell death0.0001295Direct
TNF receptor-like0.0007054Direct


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
MHC antigen-recognition domain0.00000000002315Direct
Immunoglobulin0.0000002503Direct
Bcl-2 inhibitors of programmed cell death0.00008628Direct
TNF receptor-like0.000829Direct
Complement control module/SCR domain0.0009192Direct

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
54452,48726
  • 54452 - MHC antigen-recognition domain
  • 48726 - Immunoglobulin
  • 0.000000000006777Direct
    57586,57586
  • 57586 - TNF receptor-like
  • 57586 - TNF receptor-like
  • 0.0004003Direct


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
    (show help)