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Disease Ontology (DO): eye and adnexa disease

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Root: DO Hierarchy (disease ontology from University of Maryland)

Shortest distance to current term (+ for parents, - for children) DO term [DO ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + 4:   disease [DOID:4] <8>
+ + + 3:   disease of anatomical entity [DOID:7] <12>(143|187) (147|103|58)
+ + 2:   nervous system disease [DOID:863] <11>(51|61) (54|28|13)
+ 1:   sensory system disease [DOID:0050155] <2>(16|13) (17|5|2)
0:   eye and adnexa disease [DOID:1492] <3>(13|11) (14|5|2)
- 1:   eye disease [DOID:5614] <34>(13|11) (14|5|2)
- 1:   vitreous disease [DOID:9720] <5>(0|0) (0|0|0)
- 1:   eye adnexa disease [DOID:0050815] <2>(0|0) (0|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
gamma-Crystallin-like0.0000000001778Direct
TNF-like0.006312Inherited
PGBD-like0.00666Inherited
L domain-like0.01132Inherited
4-helical cytokines0.01381Inherited
TIMP-like0.02213Inherited
Hemopexin-like domain0.05588Inherited
MHC antigen-recognition domain0.06586Inherited
RNI-like0.09532Inherited
Complement control module/SCR domain0.4473Inherited
Metalloproteases ("zincins"), catalytic domain0.4815Inherited
Cytokine0.7569Inherited
Kringle-like0.7569Inherited


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Family

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SCOP termFDR (all)Annotation (direct or inherited)
Crystallins/Ca-binding development proteins0.0000000001668Direct
Ngr ectodomain-like0.002419Inherited
MMP N-terminal domain0.005862Inherited
TNF-like0.005862Inherited
Interleukin-1 (IL-1)0.008372Inherited
Matrix metalloproteases, catalytic domain0.01256Inherited
Hemopexin-like domain0.05227Inherited
MHC antigen-recognition domain0.06345Inherited
C1 set domains (antibody constant domain-like)0.06345Inherited
Complement control module/SCR domain0.4042Inherited
Transforming growth factor (TGF)-beta0.6588Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
gamma-Crystallin-like0.00000000008236Direct
TNF-like0.004324Inherited
PGBD-like0.004577Inherited
L domain-like0.007953Inherited
4-helical cytokines0.009786Inherited
TIMP-like0.01609Inherited
Hemopexin-like domain0.04273Inherited
MHC antigen-recognition domain0.05093Inherited
RNI-like0.07547Inherited
Complement control module/SCR domain0.3899Inherited
Metalloproteases ("zincins"), catalytic domain0.4221Inherited
Kringle-like0.6847Inherited
Cytokine0.6847Inherited
Trypsin-like serine proteases0.7738Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
47090,55486
  • 47090 - PGBD-like
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 0.004577Inherited
    54452,48726
  • 54452 - MHC antigen-recognition domain
  • 48726 - Immunoglobulin
  • 0.03415Inherited
    49899,49899
  • 49899 - Concanavalin A-like lectins/glucanases
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.06635Inherited
    57535,57535
  • 57535 - Complement control module/SCR domain
  • 57535 - Complement control module/SCR domain
  • 0.4581Inherited
    57440,57440
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 0.6847Inherited

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    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    57440,57440,57440
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 0.002195Inherited
    57535,57535,57535
  • 57535 - Complement control module/SCR domain
  • 57535 - Complement control module/SCR domain
  • 57535 - Complement control module/SCR domain
  • 0.4974Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
    (show help)