SUPERFAMILY 1.75 HMM library and genome assignments server

Superfamily is undergoing a server migration - you are now browsing on the new server. Please contact us if you experience any problems.

Disease Ontology (DO): rheumatic disease

(show info)

Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Root: DO Hierarchy (disease ontology from University of Maryland)

Shortest distance to current term (+ for parents, - for children) DO term [DO ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + + 5:   disease [DOID:4] <8>
+ + + + 4:   disease of anatomical entity [DOID:7] <12>(143|187) (147|103|58)
+ + + 3:   immune system disease [DOID:2914] <4>(39|47) (42|27|16)
+ + 2:   hypersensitivity reaction disease [DOID:0060056] <5>(35|46) (37|23|14)
+ 1:   hypersensitivity reaction type II disease [DOID:417] <26>(33|43) (35|23|14)
0:   rheumatic disease [DOID:1575] <1>(6|10) (7|2|1)
- 1:   scleroderma [DOID:419] <2>(6|10) (7|2|1)


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Superfamily

(show details)
SCOP termFDR (all)Annotation (direct or inherited)
SMAD MH1 domain0.0001831Direct
PGBD-like0.001747Inherited
Hemopexin-like domain0.001747Inherited
Interleukin 8-like chemokines0.1495Inherited
TNF-like0.198Inherited
4-helical cytokines0.3165Inherited


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Family

(show details)
SCOP termFDR (all)Annotation (direct or inherited)
Pentraxin (pentaxin)0.00002544Direct
SMAD domain0.0001326Direct
SMAD MH1 domain0.0001326Direct
Platelet-derived growth factor-like0.0002352Direct
Matrix metalloproteases, catalytic domain0.001161Inherited
MMP N-terminal domain0.001161Inherited
Hemopexin-like domain0.001161Inherited
Interleukin-1 (IL-1)0.03622Inherited
Interleukin 8-like chemokines0.1241Inherited
TNF-like0.1676Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
Plot tree as:   Download Newick format tree:
(show help)

Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

(show details)
Supra-domain (Single) FDR (all) Annotation (direct or inherited)
SMAD MH1 domain0.0001089Direct
Hemopexin-like domain0.001122Inherited
PGBD-like0.001122Inherited
Snake toxin-like0.0129Inherited
Interleukin 8-like chemokines0.121Inherited
TNF-like0.1632Inherited
4-helical cytokines0.2706Inherited

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
47090,55486
  • 47090 - PGBD-like
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 0.001122Inherited
    57440,57440
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 0.1733Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    57440,57440,57440
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 0.03535Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
    (show help)