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Disease Ontology (DO): urinary system disease

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Root: DO Hierarchy (disease ontology from University of Maryland)

Shortest distance to current term (+ for parents, - for children) DO term [DO ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + 2:   disease [DOID:4] <8>
+ 1:   disease of anatomical entity [DOID:7] <12>(143|187) (147|103|58)
0:   urinary system disease [DOID:18] <10>(20|29) (22|11|6)
- 1:   kidney disease [DOID:557] <24>(19|28) (21|11|6)
- 1:   urethral disease [DOID:732] <9>(0|0) (0|0|0)
- 1:   bladder disease [DOID:365] <7>(0|0) (0|0|0)
- 1:   ureteral disease [DOID:1426] <5>(0|0) (0|0|0)
- 1:   lower urinary tract calculus [DOID:9590] <3>(0|0) (0|0|0)
- 1:   urinary tract obstruction [DOID:5200] <2>(0|0) (0|0|0)
- 1:   bacteriuria [DOID:1412](0|0) (0|0|0)
- 1:   neonatal urinary tract infectious disease [DOID:1375](0|0) (0|0|0)
- 1:   pyuria [DOID:1439](0|0) (0|0|0)
- 1:   urinary schistosomiasis [DOID:1394](0|0) (0|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
Nitric oxide (NO) synthase oxygenase domain0Direct
TNF receptor-like0.00005411Direct
Kringle-like0.0002676Direct
TNF-like0.0003573Direct
4-helical cytokines0.000486Direct
GLA-domain0.000533Direct
STAT0.001714Inherited
Transcription factor STAT-4 N-domain0.001714Inherited
SMAD MH1 domain0.001714Inherited
Anaphylotoxins (complement system)0.002317Inherited
Apolipoprotein A-I0.002317Inherited
Alpha-macroglobulin receptor domain0.00755Inherited
Terpenoid cyclases/Protein prenyltransferases0.01621Inherited
C-type lectin-like0.02446Inherited
Flavoproteins0.02771Inherited
Complement control module/SCR domain0.0304Inherited
Heme-dependent peroxidases0.04353Inherited
Immunoglobulin0.04885Inherited
Serpins0.2106Inherited
Fibronectin type III0.2508Inherited


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Family

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SCOP termFDR (all)Annotation (direct or inherited)
Nitric oxide (NO) synthase oxygenase domain0Direct
Noncollagenous (NC1) domain of collagen IV0.000002507Direct
TNF receptor-like0.00004813Direct
TNF-like0.0002752Direct
GLA-domain0.0003826Direct
STAT DNA-binding domain0.001217Inherited
SMAD MH1 domain0.001217Inherited
STAT0.001217Inherited
SMAD domain0.001217Inherited
Transcription factor STAT-4 N-domain0.001217Inherited
Cytochrome p450 reductase N-terminal domain-like0.001663Inherited
Netrin-like domain (NTR/C345C module)0.001663Inherited
Apolipoprotein A-I0.001663Inherited
Anaphylotoxins (complement system)0.001663Inherited
Retinol binding protein-like0.003105Inherited
C2 set domains0.003105Inherited
NADPH-cytochrome p450 reductase FAD-binding domain-like0.005606Inherited
NADPH-cytochrome p450 reductase-like0.005606Inherited
Alpha-macroglobulin receptor domain0.005606Inherited
Complement components0.005606Inherited
Interleukin-1 (IL-1)0.006206Inherited
Long-chain cytokines0.01722Inherited
Complement control module/SCR domain0.02564Inherited
Myeloperoxidase-like0.03534Inherited
Interferons/interleukin-10 (IL-10)0.04817Inherited
Growth factor receptor domain0.0516Inherited
I set domains0.1456Inherited
Serpins0.1631Inherited
Fibronectin type III0.2379Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Nitric oxide (NO) synthase oxygenase domain0Direct
TNF receptor-like0.00003119Direct
Kringle-like0.0001619Direct
TNF-like0.0002167Direct
4-helical cytokines0.0002973Direct
GLA-domain0.0003267Direct
STAT0.001098Inherited
SMAD MH1 domain0.001098Inherited
Transcription factor STAT-4 N-domain0.001098Inherited
Apolipoprotein A-I0.001524Inherited
Anaphylotoxins (complement system)0.001524Inherited
Alpha-macroglobulin receptor domain0.005203Inherited
Terpenoid cyclases/Protein prenyltransferases0.01155Inherited
C-type lectin-like0.01792Inherited
Flavoproteins0.02044Inherited
Complement control module/SCR domain0.02255Inherited
Heme-dependent peroxidases0.03283Inherited
Immunoglobulin0.03705Inherited
Cytokine0.04035Inherited
Cystine-knot cytokines0.05227Inherited
Serpins0.1745Inherited
Fibronectin type III0.2102Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
57586,57586
  • 57586 - TNF receptor-like
  • 57586 - TNF receptor-like
  • 0.00001876Direct
    57440,57440
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 0.0001248Direct
    56436,56436
  • 56436 - C-type lectin-like
  • 56436 - C-type lectin-like
  • 0.0003267Direct
    49417,55550
  • 49417 - p53-like transcription factors
  • 55550 - SH2 domain
  • 0.001098Inherited
    57630,57196
  • 57630 - GLA-domain
  • 57196 - EGF/Laminin
  • 0.001098Inherited
    48092,47655
  • 48092 - Transcription factor STAT-4 N-domain
  • 47655 - STAT
  • 0.001098Inherited
    47655,49417
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 0.001098Inherited
    49410,50242
  • 49410 - Alpha-macroglobulin receptor domain
  • 50242 - TIMP-like
  • 0.001524Inherited
    57535,57535
  • 57535 - Complement control module/SCR domain
  • 57535 - Complement control module/SCR domain
  • 0.01848Inherited
    48726,49265
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 0.05941Inherited
    48726,48726
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 0.09721Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    57440,57440,57440
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 0.00004189Direct
    47655,49417,55550
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 55550 - SH2 domain
  • 0.001098Inherited
    48092,47655,49417
  • 48092 - Transcription factor STAT-4 N-domain
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 0.001098Inherited
    57586,57586,57586
  • 57586 - TNF receptor-like
  • 57586 - TNF receptor-like
  • 57586 - TNF receptor-like
  • 0.005667Inherited
    57535,57535,57535
  • 57535 - Complement control module/SCR domain
  • 57535 - Complement control module/SCR domain
  • 57535 - Complement control module/SCR domain
  • 0.04035Inherited
    48726,48726,49265
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 0.252Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
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