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Disease Ontology (DO): reproductive organ cancer

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Root: DO Hierarchy (disease ontology from University of Maryland)

Shortest distance to current term (+ for parents, - for children) DO term [DO ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + 4:   disease [DOID:4] <8>
+ + + 3:   disease of cellular proliferation [DOID:14566] <3>(123|191) (129|118|56)
+ + 2:   cancer [DOID:162] <2>(115|181) (120|113|54)
+ 1:   organ system cancer [DOID:0050686] <14>(66|106) (72|58|31)
0:   reproductive organ cancer [DOID:193] <3>(11|14) (12|10|3)
- 1:   male reproductive organ cancer [DOID:3856] <10>(5|8) (5|7|3)
- 1:   female reproductive organ cancer [DOID:120] <9>(9|11) (10|6|2)
- 1:   sex cord-gonadal stromal tumor [DOID:192] <4>(0|0) (0|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
PGBD-like0.000005559Direct
Cystine-knot cytokines0.00000652Direct
Hemopexin-like domain0.00001639Direct
Nuclear receptor ligand-binding domain0.0002136Direct
Metalloproteases ("zincins"), catalytic domain0.000381Direct
Glucocorticoid receptor-like (DNA-binding domain)0.02137Inherited
Inhibitor of apoptosis (IAP) repeat0.04066Inherited
Protein kinase-like (PK-like)0.04111Inherited
4-helical cytokines0.05648Inherited
Nucleotide-diphospho-sugar transferases0.5218Inherited
Immunoglobulin0.5475Inherited


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Family

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SCOP termFDR (all)Annotation (direct or inherited)
MMP N-terminal domain0.000003853Direct
Hemopexin-like domain0.00001165Direct
Matrix metalloproteases, catalytic domain0.00001165Direct
Nuclear receptor ligand-binding domain0.0001647Direct
Nuclear receptor0.0002698Direct
Transforming growth factor (TGF)-beta0.0004047Direct
L domain0.004487Inherited
Long-chain cytokines0.007023Inherited
Extracellular domain of cell surface receptors0.01074Inherited
DNA gyrase/MutL, N-terminal domain0.01539Inherited
DNA gyrase/MutL, second domain0.01539Inherited
Inhibitor of apoptosis (IAP) repeat0.03243Inherited
Growth factor receptor domain0.04756Inherited
Protein kinases, catalytic subunit0.06157Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
PGBD-like0.00000299Direct
Cystine-knot cytokines0.000003515Direct
Hemopexin-like domain0.000009108Direct
Nuclear receptor ligand-binding domain0.000128Direct
Metalloproteases ("zincins"), catalytic domain0.0002319Direct
Glucocorticoid receptor-like (DNA-binding domain)0.01552Inherited
Inhibitor of apoptosis (IAP) repeat0.03053Inherited
Protein kinase-like (PK-like)0.03092Inherited
4-helical cytokines0.04326Inherited
p53-like transcription factors0.09978Inherited
Nucleotide-diphospho-sugar transferases0.4601Inherited
Immunoglobulin0.4848Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
47090,55486
  • 47090 - PGBD-like
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 0.00000299Direct
    55486,50923
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 50923 - Hemopexin-like domain
  • 0.0004192Direct
    57184,52058
  • 57184 - Growth factor receptor domain
  • 52058 - L domain-like
  • 0.004189Inherited
    52058,57184
  • 52058 - L domain-like
  • 57184 - Growth factor receptor domain
  • 0.004189Inherited
    57924,57924
  • 57924 - Inhibitor of apoptosis (IAP) repeat
  • 57924 - Inhibitor of apoptosis (IAP) repeat
  • 0.0144Inherited
    55874,54211
  • 55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
  • 54211 - Ribosomal protein S5 domain 2-like
  • 0.0144Inherited
    81296,81296
  • 81296 - E set domains
  • 81296 - E set domains
  • 0.01698Inherited
    57716,48508
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 48508 - Nuclear receptor ligand-binding domain
  • 0.03347Inherited
    57440,57440
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 0.08158Inherited
    48726,48726
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 0.5231Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    47090,55486,50923
  • 47090 - PGBD-like
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 50923 - Hemopexin-like domain
  • 0.000173Direct
    52058,57184,52058
  • 52058 - L domain-like
  • 57184 - Growth factor receptor domain
  • 52058 - L domain-like
  • 0.004189Inherited
    57440,57440,57440
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 0.0144Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
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