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Disease Ontology (DO): atherosclerosis

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Root: DO Hierarchy (disease ontology from University of Maryland)

Shortest distance to current term (+ for parents, - for children) DO term [DO ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + + + + 7:   disease [DOID:4] <8>
+ + + + + + 6:   disease of anatomical entity [DOID:7] <12>(143|187) (147|103|58)
+ + + + + 5:   cardiovascular system disease [DOID:1287] <3>(41|53) (41|24|14)
+ + + + 4:   vascular disease [DOID:178] <13>(37|48) (38|22|11)
+ + + 3:   artery disease [DOID:0050828] <12>(29|34) (31|15|8)
+ + 2:   arteriosclerosis [DOID:2349] <6>(13|14) (13|9|3)
+ 1:   arteriosclerotic cardiovascular disease [DOID:2348] <1>(13|14) (13|9|3)
0:   atherosclerosis [DOID:1936] <3>(13|14) (13|9|3)
- 1:   aortic atherosclerosis [DOID:10230](0|0) (0|0|0)
- 1:   cerebral atherosclerosis [DOID:12720](0|0) (0|0|0)
- 1:   generalized atherosclerosis [DOID:2347](0|0) (0|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
Apolipoprotein A-I0Direct
Metalloproteases ("zincins"), catalytic domain0.000000007109Direct
Kringle-like0.00000006024Direct
TNF-like0.000001742Direct
PGBD-like0.00001303Direct
Blood coagulation inhibitor (disintegrin)0.0000204Direct
GLA-domain0.00004929Direct
Hemopexin-like domain0.00007221Direct
Lipase/lipooxygenase domain (PLAT/LH2 domain)0.0002629Direct
MAPEG domain-like0.0003867Direct
Phospholipase A2, PLA20.0003867Direct
TNF receptor-like0.0007536Direct
EGF/Laminin0.0009695Direct


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Family

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SCOP termFDR (all)Annotation (direct or inherited)
Apolipoprotein A-I0Direct
TNF-like0.000001768Direct
Kringle modules0.000001955Direct
MMP N-terminal domain0.00001173Direct
Blood coagulation inhibitor (disintegrin)0.00001777Direct
GLA-domain0.00004171Direct
Matrix metalloproteases, catalytic domain0.00004546Direct
Hemopexin-like domain0.00006609Direct
Interleukin-1 (IL-1)0.0001749Direct
Platelet-derived growth factor-like0.0001749Direct
TNF receptor-like0.0002617Direct
Pentraxin (pentaxin)0.0002989Direct
Fibronectin type II module0.0005936Direct
Pancreatic lipase, N-terminal domain0.0007402Direct


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Apolipoprotein A-I0Direct
Metalloproteases ("zincins"), catalytic domain0.000000003342Direct
Kringle-like0.00000002921Direct
TNF-like0.0000009118Direct
PGBD-like0.000007169Direct
Blood coagulation inhibitor (disintegrin)0.00001138Direct
GLA-domain0.0000284Direct
Hemopexin-like domain0.00004213Direct
Lipase/lipooxygenase domain (PLAT/LH2 domain)0.0001589Direct
MAPEG domain-like0.0002362Direct
Phospholipase A2, PLA20.0002362Direct
TNF receptor-like0.0004661Direct
EGF/Laminin0.0006084Direct

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
57440,57440
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 0.000000005268Direct
    57440,50494
  • 57440 - Kringle-like
  • 50494 - Trypsin-like serine proteases
  • 0.0000003588Direct
    47090,55486
  • 47090 - PGBD-like
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 0.000007169Direct
    55486,57552
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 57552 - Blood coagulation inhibitor (disintegrin)
  • 0.00001138Direct
    57586,57586
  • 57586 - TNF receptor-like
  • 57586 - TNF receptor-like
  • 0.000124Direct
    53474,49723
  • 53474 - alpha/beta-Hydrolases
  • 49723 - Lipase/lipooxygenase domain (PLAT/LH2 domain)
  • 0.0002362Direct
    57184,63825
  • 57184 - Growth factor receptor domain
  • 63825 - YWTD domain
  • 0.0002362Direct
    55486,50923
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 50923 - Hemopexin-like domain
  • 0.0005466Direct
    57630,57196
  • 57630 - GLA-domain
  • 57196 - EGF/Laminin
  • 0.0005956Direct

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    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    57440,57440,50494
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 50494 - Trypsin-like serine proteases
  • 0.0000195Direct
    57440,57440,57440
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 0.0000195Direct
    47090,55486,50923
  • 47090 - PGBD-like
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 50923 - Hemopexin-like domain
  • 0.0002494Direct


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
    (show help)