SUPERFAMILY 1.75 HMM library and genome assignments server

Superfamily is undergoing a server migration - you are now browsing on the new server. Please contact us if you experience any problems.

Disease Ontology (DO): arteriosclerotic cardiovascular disease

(show info)

Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Root: DO Hierarchy (disease ontology from University of Maryland)

Shortest distance to current term (+ for parents, - for children) DO term [DO ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + + + 6:   disease [DOID:4] <8>
+ + + + + 5:   disease of anatomical entity [DOID:7] <12>(143|187) (147|103|58)
+ + + + 4:   cardiovascular system disease [DOID:1287] <3>(41|53) (41|24|14)
+ + + 3:   vascular disease [DOID:178] <13>(37|48) (38|22|11)
+ + 2:   artery disease [DOID:0050828] <12>(29|34) (31|15|8)
+ 1:   arteriosclerosis [DOID:2349] <6>(13|14) (13|9|3)
0:   arteriosclerotic cardiovascular disease [DOID:2348] <1>(13|14) (13|9|3)
- 1:   atherosclerosis [DOID:1936] <3>(13|14) (13|9|3)


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Superfamily

(show details)
SCOP termFDR (all)Annotation (direct or inherited)
Apolipoprotein A-I0Direct
Metalloproteases ("zincins"), catalytic domain0.0000000075Direct
Kringle-like0.00000006213Direct
TNF-like0.000001796Direct
PGBD-like0.00001333Direct
Blood coagulation inhibitor (disintegrin)0.00002078Direct
GLA-domain0.00004997Direct
Hemopexin-like domain0.0000737Direct
Lipase/lipooxygenase domain (PLAT/LH2 domain)0.000267Direct
MAPEG domain-like0.0003912Direct
Phospholipase A2, PLA20.0003912Direct
TNF receptor-like0.0007648Direct
EGF/Laminin0.001006Inherited


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Family

(show details)
SCOP termFDR (all)Annotation (direct or inherited)
Apolipoprotein A-I0Direct
TNF-like0.000001824Direct
Kringle modules0.000001997Direct
MMP N-terminal domain0.000012Direct
Blood coagulation inhibitor (disintegrin)0.00001808Direct
GLA-domain0.00004246Direct
Matrix metalloproteases, catalytic domain0.00004642Direct
Hemopexin-like domain0.00006763Direct
Interleukin-1 (IL-1)0.0001773Direct
Platelet-derived growth factor-like0.0001773Direct
TNF receptor-like0.0002669Direct
Pentraxin (pentaxin)0.0003023Direct
Fibronectin type II module0.0006022Direct
Pancreatic lipase, N-terminal domain0.0007483Direct


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
Plot tree as:   Download Newick format tree:
(show help)

Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

(show details)
Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Apolipoprotein A-I0Direct
Metalloproteases ("zincins"), catalytic domain0.000000003531Direct
Kringle-like0.00000003019Direct
TNF-like0.0000009418Direct
PGBD-like0.000007335Direct
Blood coagulation inhibitor (disintegrin)0.00001161Direct
GLA-domain0.00002881Direct
Hemopexin-like domain0.00004309Direct
Lipase/lipooxygenase domain (PLAT/LH2 domain)0.0001616Direct
MAPEG domain-like0.0002391Direct
Phospholipase A2, PLA20.0002391Direct
TNF receptor-like0.0004742Direct
EGF/Laminin0.0006316Direct

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
57440,57440
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 0.000000005405Direct
    57440,50494
  • 57440 - Kringle-like
  • 50494 - Trypsin-like serine proteases
  • 0.0000003663Direct
    47090,55486
  • 47090 - PGBD-like
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 0.000007335Direct
    55486,57552
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 57552 - Blood coagulation inhibitor (disintegrin)
  • 0.00001161Direct
    57586,57586
  • 57586 - TNF receptor-like
  • 57586 - TNF receptor-like
  • 0.0001261Direct
    53474,49723
  • 53474 - alpha/beta-Hydrolases
  • 49723 - Lipase/lipooxygenase domain (PLAT/LH2 domain)
  • 0.0002391Direct
    57184,63825
  • 57184 - Growth factor receptor domain
  • 63825 - YWTD domain
  • 0.0002391Direct
    55486,50923
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 50923 - Hemopexin-like domain
  • 0.0005557Direct
    57630,57196
  • 57630 - GLA-domain
  • 57196 - EGF/Laminin
  • 0.0006024Direct

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    57440,57440,50494
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 50494 - Trypsin-like serine proteases
  • 0.00001979Direct
    57440,57440,57440
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 0.00001979Direct
    47090,55486,50923
  • 47090 - PGBD-like
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 50923 - Hemopexin-like domain
  • 0.0002536Direct


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
    (show help)