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Disease Ontology (DO): arteriosclerosis

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Root: DO Hierarchy (disease ontology from University of Maryland)

Shortest distance to current term (+ for parents, - for children) DO term [DO ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + + 5:   disease [DOID:4] <8>
+ + + + 4:   disease of anatomical entity [DOID:7] <12>(143|187) (147|103|58)
+ + + 3:   cardiovascular system disease [DOID:1287] <3>(41|53) (41|24|14)
+ + 2:   vascular disease [DOID:178] <13>(37|48) (38|22|11)
+ 1:   artery disease [DOID:0050828] <12>(29|34) (31|15|8)
0:   arteriosclerosis [DOID:2349] <6>(13|14) (13|9|3)
- 1:   arteriosclerotic cardiovascular disease [DOID:2348] <1>(13|14) (13|9|3)
- 1:   Monckeberg arteriosclerosis [DOID:5161](0|0) (0|0|0)
- 1:   arteriolosclerosis [DOID:5162](0|0) (0|0|0)
- 1:   arteriosclerosis obliterans [DOID:5160](0|0) (0|0|0)
- 1:   intermittent claudication [DOID:3669](0|0) (0|0|0)
- 1:   intracranial arteriosclerosis [DOID:13097](0|0) (0|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
Apolipoprotein A-I0Direct
Kringle-like0.0004146Direct
MAPEG domain-like0.0004366Direct
Phospholipase A2, PLA20.0004366Direct
PGBD-like0.004217Inherited
Metalloproteases ("zincins"), catalytic domain0.006498Inherited
TNF-like0.006954Inherited
Blood coagulation inhibitor (disintegrin)0.008777Inherited
Hemopexin-like domain0.01654Inherited
Lipase/lipooxygenase domain (PLAT/LH2 domain)0.01786Inherited
GLA-domain0.05668Inherited
TNF receptor-like0.06922Inherited
EGF/Laminin0.2994Inherited


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Family

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SCOP termFDR (all)Annotation (direct or inherited)
Apolipoprotein A-I0Direct
Interleukin-1 (IL-1)0.0001985Direct
Pentraxin (pentaxin)0.0003341Direct
Fibronectin type II module0.0006722Direct
Pancreatic lipase, N-terminal domain0.0008198Direct
MMP N-terminal domain0.002784Inherited
Kringle modules0.002784Inherited
Matrix metalloproteases, catalytic domain0.002784Inherited
TNF-like0.004697Inherited
Blood coagulation inhibitor (disintegrin)0.005966Inherited
Hemopexin-like domain0.01167Inherited
Platelet-derived growth factor-like0.02685Inherited
GLA-domain0.0431Inherited
TNF receptor-like0.05345Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Apolipoprotein A-I0Direct
Kringle-like0.0002532Direct
MAPEG domain-like0.000267Direct
Phospholipase A2, PLA20.000267Direct
PGBD-like0.002839Inherited
Metalloproteases ("zincins"), catalytic domain0.00445Inherited
TNF-like0.004789Inherited
Blood coagulation inhibitor (disintegrin)0.006044Inherited
Hemopexin-like domain0.01181Inherited
Lipase/lipooxygenase domain (PLAT/LH2 domain)0.01285Inherited
GLA-domain0.04342Inherited
TNF receptor-like0.05371Inherited
EGF/Laminin0.2549Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
53474,49723
  • 53474 - alpha/beta-Hydrolases
  • 49723 - Lipase/lipooxygenase domain (PLAT/LH2 domain)
  • 0.000267Direct
    57184,63825
  • 57184 - Growth factor receptor domain
  • 63825 - YWTD domain
  • 0.000267Direct
    47090,55486
  • 47090 - PGBD-like
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 0.002839Inherited
    57440,57440
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 0.002839Inherited
    55486,57552
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 57552 - Blood coagulation inhibitor (disintegrin)
  • 0.006044Inherited
    57440,50494
  • 57440 - Kringle-like
  • 50494 - Trypsin-like serine proteases
  • 0.006044Inherited
    55486,50923
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 50923 - Hemopexin-like domain
  • 0.01285Inherited
    57586,57586
  • 57586 - TNF receptor-like
  • 57586 - TNF receptor-like
  • 0.02265Inherited
    57630,57196
  • 57630 - GLA-domain
  • 57196 - EGF/Laminin
  • 0.1505Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    47090,55486,50923
  • 47090 - PGBD-like
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 50923 - Hemopexin-like domain
  • 0.01285Inherited
    57440,57440,50494
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 50494 - Trypsin-like serine proteases
  • 0.0272Inherited
    57440,57440,57440
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 0.0272Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
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