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Disease Ontology (DO): asthma

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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Root: DO Hierarchy (disease ontology from University of Maryland)

Shortest distance to current term (+ for parents, - for children) DO term [DO ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + + 5:   disease [DOID:4] <8>
+ + + + 4:   disease of anatomical entity [DOID:7] <12>(143|187) (147|103|58)
+ + + 3:   respiratory system disease [DOID:1579] <4>(29|38) (30|14|7)
+ + 2:   lower respiratory tract disease [DOID:0050161] <3>(25|33) (26|13|7)
+ 1:   bronchial disease [DOID:1176] <3>(17|24) (17|8|2)
0:   asthma [DOID:2841] <4>(13|18) (13|6|2)
- 1:   allergic asthma [DOID:9415](1|1) (1|0|0)
- 1:   cough variant asthma [DOID:12323](0|0) (0|0|0)
- 1:   intrinsic asthma [DOID:9360](0|0) (0|0|0)
- 1:   status asthmaticus [DOID:9362](0|0) (0|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
Nitric oxide (NO) synthase oxygenase domain0Direct
Toll/Interleukin receptor TIR domain0.000000000003305Direct
4-helical cytokines0.00000000001772Direct
Family A G protein-coupled receptor-like0.0000003616Direct
Cystine-knot cytokines0.00004335Direct
Interleukin 8-like chemokines0.0001137Direct
Flavoproteins0.0001207Direct
STAT0.0001207Direct
Transcription factor STAT-4 N-domain0.0001207Direct
Anaphylotoxins (complement system)0.0001215Direct
Chitinase insertion domain0.0001215Direct
Triple coiled coil domain of C-type lectins0.0004575Direct
Snake toxin-like0.0007383Direct


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Family

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SCOP termFDR (all)Annotation (direct or inherited)
Nitric oxide (NO) synthase oxygenase domain0Direct
Neurotrophin0Direct
Toll/Interleukin receptor TIR domain0.00000000000142Direct
Short-chain cytokines0.000000001294Direct
Rhodopsin-like0.0000008066Direct
Cytochrome p450 reductase N-terminal domain-like0.00009631Direct
Netrin-like domain (NTR/C345C module)0.00009631Direct
Interleukin 17F, IL-17F0.00009631Direct
Chitinase insertion domain0.00009631Direct
Anaphylotoxins (complement system)0.00009631Direct
Type II chitinase0.00009631Direct
STAT DNA-binding domain0.0001006Direct
STAT0.0001006Direct
Transcription factor STAT-4 N-domain0.0001006Direct
Interleukin 8-like chemokines0.0001213Direct
NADPH-cytochrome p450 reductase FAD-binding domain-like0.0003625Direct
NADPH-cytochrome p450 reductase-like0.0003625Direct
Triple coiled coil domain of C-type lectins0.0003625Direct


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Nitric oxide (NO) synthase oxygenase domain0Direct
Toll/Interleukin receptor TIR domain0.000000000001491Direct
4-helical cytokines0.000000000008033Direct
Family A G protein-coupled receptor-like0.0000001831Direct
Cystine-knot cytokines0.00002494Direct
Interleukin 8-like chemokines0.0000671Direct
STAT0.00007144Direct
Transcription factor STAT-4 N-domain0.00007144Direct
Flavoproteins0.00007144Direct
Chitinase insertion domain0.00007188Direct
Anaphylotoxins (complement system)0.00007188Direct
Triple coiled coil domain of C-type lectins0.0002795Direct
Snake toxin-like0.0004552Direct

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
49417,55550
  • 49417 - p53-like transcription factors
  • 55550 - SH2 domain
  • 0.00007144Direct
    48092,47655
  • 48092 - Transcription factor STAT-4 N-domain
  • 47655 - STAT
  • 0.00007144Direct
    47655,49417
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 0.00007144Direct
    51445,54556
  • 51445 - (Trans)glycosidases
  • 54556 - Chitinase insertion domain
  • 0.00007188Direct
    49410,50242
  • 49410 - Alpha-macroglobulin receptor domain
  • 50242 - TIMP-like
  • 0.00007188Direct
    57944,56436
  • 57944 - Triple coiled coil domain of C-type lectins
  • 56436 - C-type lectin-like
  • 0.0002795Direct

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    47655,49417,55550
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 55550 - SH2 domain
  • 0.00007144Direct
    48092,47655,49417
  • 48092 - Transcription factor STAT-4 N-domain
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 0.00007144Direct


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
    (show help)