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Disease Ontology (DO): carcinoma

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Root: DO Hierarchy (disease ontology from University of Maryland)

Shortest distance to current term (+ for parents, - for children) DO term [DO ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + 4:   disease [DOID:4] <8>
+ + + 3:   disease of cellular proliferation [DOID:14566] <3>(123|191) (129|118|56)
+ + 2:   cancer [DOID:162] <2>(115|181) (120|113|54)
+ 1:   cell type cancer [DOID:0050687] <11>(23|40) (25|27|17)
0:   carcinoma [DOID:305] <13>(13|26) (15|19|9)
- 1:   adenocarcinoma [DOID:299] <9>(1|3) (3|2|2)
- 1:   squamous cell carcinoma [DOID:1749] <7>(1|3) (1|1|1)
- 1:   transitional cell carcinoma [DOID:2671] <2>(0|0) (0|0|0)
- 1:   NUT midline carcinoma [DOID:0060463](0|0) (0|0|0)
- 1:   acinar cell carcinoma [DOID:3025](0|0) (0|0|0)
- 1:   granular cell carcinoma [DOID:4903](0|0) (0|0|0)
- 1:   large cell carcinoma [DOID:4552](0|0) (0|0|0)
- 1:   lymphoepithelioma-like carcinoma [DOID:5660](0|0) (0|0|0)
- 1:   myoepithelial carcinoma [DOID:4838](0|0) (0|0|0)
- 1:   neuroendocrine carcinoma [DOID:1800](2|1) (2|1|0)
- 1:   papillary carcinoma [DOID:3113](0|1) (0|0|0)
- 1:   pleomorphic carcinoma [DOID:5662](0|0) (0|0|0)
- 1:   small cell carcinoma [DOID:0050685](0|0) (0|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
Insulin-like0Direct
Nuclear receptor coactivator interlocking domain0Direct
Synuclein0Direct
HSP90 C-terminal domain0Direct
Lesion bypass DNA polymerase (Y-family), little finger domain0Direct
Purine and uridine phosphorylases0Direct
p53 tetramerization domain0Direct
FAS1 domain0Direct
PGBD-like0.000001601Direct
Hemopexin-like domain0.00004304Direct
Bcl-2 inhibitors of programmed cell death0.0002382Direct
Intermediate filament protein, coiled coil region0.128Inherited
Prefoldin0.2805Inherited


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Family

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SCOP termFDR (all)Annotation (direct or inherited)
Purine and uridine phosphorylases0Direct
Hsp90 middle domain0Direct
p53 tetramerization domain0Direct
FAS1 domain0Direct
Gelsolin-like0Direct
Lesion bypass DNA polymerase (Y-family), catalytic domain0Direct
HSP90 C-terminal domain0Direct
Heat shock protein 90, HSP90, N-terminal domain0Direct
Uteroglobin-like0Direct
Insulin-like0Direct
Synuclein0Direct
p53 DNA-binding domain-like0Direct
Nuclear receptor coactivator interlocking domain0Direct
L domain0Direct
Retinoblastoma tumor suppressor domains0Direct
PAS domain of steroid receptor coactivator 1A, NCo-A10Direct
Matrix metalloproteases, catalytic domain0.0000009943Direct
MMP N-terminal domain0.000001312Direct
Ephrin receptor ligand binding domain0.00001017Direct
Hemopexin-like domain0.00003742Direct
Bcl-2 inhibitors of programmed cell death0.0001877Direct
Platelet-derived growth factor-like0.0006213Direct
C5 cytosine-specific DNA methylase, DCM0.02782Inherited
Hexokinase0.02782Inherited
Intermediate filament protein, coiled coil region0.1091Inherited
Protein kinase cysteine-rich domain (cys2, phorbol-binding domain)0.1779Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Lesion bypass DNA polymerase (Y-family), little finger domain0Direct
Purine and uridine phosphorylases0Direct
p53 tetramerization domain0Direct
Nuclear receptor coactivator interlocking domain0Direct
HSP90 C-terminal domain0Direct
Insulin-like0Direct
FAS1 domain0Direct
Synuclein0Direct
PGBD-like0.0000008335Direct
Hemopexin-like domain0.00002474Direct
Bcl-2 inhibitors of programmed cell death0.0001432Direct
Serine protease inhibitors0.02561Inherited
DNA-glycosylase0.02561Inherited
Intermediate filament protein, coiled coil region0.1028Inherited
Prefoldin0.2374Inherited

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
55753,55753
  • 55753 - Actin depolymerizing proteins
  • 55753 - Actin depolymerizing proteins
  • 0Direct
    57302,57302
  • 57302 - Snake toxin-like
  • 57302 - Snake toxin-like
  • 0Direct
    57196,90193
  • 57196 - EGF/Laminin
  • 90193 - Notch domain
  • 0Direct
    57184,52058
  • 57184 - Growth factor receptor domain
  • 52058 - L domain-like
  • 0Direct
    57184,57603
  • 57184 - Growth factor receptor domain
  • 57603 - FnI-like domain
  • 0Direct
    49417,47719
  • 49417 - p53-like transcription factors
  • 47719 - p53 tetramerization domain
  • 0Direct
    54236,57889
  • 54236 - Ubiquitin-like
  • 57889 - Cysteine-rich domain
  • 0Direct
    56672,100879
  • 56672 - DNA/RNA polymerases
  • 100879 - Lesion bypass DNA polymerase (Y-family), little finger domain
  • 0Direct
    49562,57889
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 57889 - Cysteine-rich domain
  • 0Direct
    57603,82895
  • 57603 - FnI-like domain
  • 82895 - TSP-1 type 1 repeat
  • 0Direct
    57184,49265
  • 57184 - Growth factor receptor domain
  • 49265 - Fibronectin type III
  • 0Direct
    52058,57184
  • 52058 - L domain-like
  • 57184 - Growth factor receptor domain
  • 0Direct
    82153,82153
  • 82153 - FAS1 domain
  • 82153 - FAS1 domain
  • 0Direct
    90193,90193
  • 90193 - Notch domain
  • 90193 - Notch domain
  • 0Direct
    47090,55486
  • 47090 - PGBD-like
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 0.0000008335Direct
    56112,47769
  • 56112 - Protein kinase-like (PK-like)
  • 47769 - SAM/Pointed domain
  • 0.00000718Direct
    55486,50923
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 50923 - Hemopexin-like domain
  • 0.00003445Direct
    49785,57184
  • 49785 - Galactose-binding domain-like
  • 57184 - Growth factor receptor domain
  • 0.00006316Direct
    46579,64593
  • 46579 - Prefoldin
  • 64593 - Intermediate filament protein, coiled coil region
  • 0.005982Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    57184,52058,57184
  • 57184 - Growth factor receptor domain
  • 52058 - L domain-like
  • 57184 - Growth factor receptor domain
  • 0Direct
    57196,57196,90193
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 90193 - Notch domain
  • 0Direct
    55753,55753,55753
  • 55753 - Actin depolymerizing proteins
  • 55753 - Actin depolymerizing proteins
  • 55753 - Actin depolymerizing proteins
  • 0Direct
    52058,48726,48726
  • 52058 - L domain-like
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 0Direct
    49562,57889,57889
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 57889 - Cysteine-rich domain
  • 57889 - Cysteine-rich domain
  • 0Direct
    52058,57184,52058
  • 52058 - L domain-like
  • 57184 - Growth factor receptor domain
  • 52058 - L domain-like
  • 0Direct
    49785,57184,49265
  • 49785 - Galactose-binding domain-like
  • 57184 - Growth factor receptor domain
  • 49265 - Fibronectin type III
  • 0Direct
    53067,53067,53067
  • 53067 - Actin-like ATPase domain
  • 53067 - Actin-like ATPase domain
  • 53067 - Actin-like ATPase domain
  • 0Direct
    47090,55486,50923
  • 47090 - PGBD-like
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 50923 - Hemopexin-like domain
  • 0.00001974Direct


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
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