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Disease Ontology (DO): nervous system cancer

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Root: DO Hierarchy (disease ontology from University of Maryland)

Shortest distance to current term (+ for parents, - for children) DO term [DO ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + 4:   disease [DOID:4] <8>
+ + + 3:   disease of cellular proliferation [DOID:14566] <3>(123|191) (129|118|56)
+ + 2:   cancer [DOID:162] <2>(115|181) (120|113|54)
+ 1:   organ system cancer [DOID:0050686] <14>(66|106) (72|58|31)
0:   nervous system cancer [DOID:3093] <5>(16|21) (17|5|2)
- 1:   central nervous system cancer [DOID:3620] <12>(6|7) (6|3|1)
- 1:   peripheral nervous system neoplasm [DOID:1192] <4>(6|7) (6|1|1)
- 1:   sensory system cancer [DOID:0060116] <2>(4|7) (5|1|0)
- 1:   nervous system hibernoma [DOID:6607](0|0) (0|0|0)
- 1:   neuroectodermal tumor [DOID:171](0|0) (0|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
Nitric oxide (NO) synthase oxygenase domain0Direct
14-3-3 protein0Direct
Flavoproteins0.00002115Direct
DPP6 N-terminal domain-like0.001964Inherited
HLH, helix-loop-helix DNA-binding domain0.002084Inherited
Cyclin-like0.007359Inherited
Protein kinase-like (PK-like)0.008689Inherited
Snake toxin-like0.01973Inherited
Second domain of FERM0.04983Inherited
Ran binding protein zinc finger-like0.05957Inherited
alpha/beta-Hydrolases0.08858Inherited
Growth factor receptor domain0.1135Inherited
Hemopexin-like domain0.2343Inherited
Kringle-like0.2343Inherited
FnI-like domain0.3437Inherited
TSP-1 type 1 repeat0.3502Inherited


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Family

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SCOP termFDR (all)Annotation (direct or inherited)
14-3-3 protein0Direct
Nitric oxide (NO) synthase oxygenase domain0Direct
Retinoblastoma tumor suppressor domains0Direct
NADPH-cytochrome p450 reductase FAD-binding domain-like0.00003222Direct
NADPH-cytochrome p450 reductase-like0.00003222Direct
Extracellular domain of cell surface receptors0.00005036Direct
DPP6 N-terminal domain-like0.0001424Direct
Cytochrome p450 reductase N-terminal domain-like0.0002938Direct
DPP6 catalytic domain-like0.001098Inherited
HLH, helix-loop-helix DNA-binding domain0.002004Inherited
FHA domain0.006076Inherited
First domain of FERM0.01495Inherited
Protein kinases, catalytic subunit0.02787Inherited
Second domain of FERM0.03515Inherited
Growth factor receptor domain0.03909Inherited
Third domain of FERM0.04996Inherited
Ran binding protein zinc finger-like0.05131Inherited
Cyclin0.056Inherited
Thyroglobulin type-1 domain0.06705Inherited
Hemopexin-like domain0.2193Inherited
TSP-1 type 1 repeat0.3345Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
14-3-3 protein0Direct
Nitric oxide (NO) synthase oxygenase domain0Direct
Flavoproteins0.00001185Direct
DPP6 N-terminal domain-like0.001274Inherited
HLH, helix-loop-helix DNA-binding domain0.001359Inherited
Cyclin-like0.005066Inherited
Protein kinase-like (PK-like)0.005978Inherited
Snake toxin-like0.01427Inherited
Second domain of FERM0.03785Inherited
Ran binding protein zinc finger-like0.04576Inherited
Thyroglobulin type-1 domain0.05933Inherited
alpha/beta-Hydrolases0.0699Inherited
Growth factor receptor domain0.09051Inherited
Kringle-like0.1954Inherited
Hemopexin-like domain0.1954Inherited
FnI-like domain0.295Inherited
TSP-1 type 1 repeat0.3009Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
82171,53474
  • 82171 - DPP6 N-terminal domain-like
  • 53474 - alpha/beta-Hydrolases
  • 0.0001063Direct
    57184,57603
  • 57184 - Growth factor receptor domain
  • 57603 - FnI-like domain
  • 0.01234Inherited
    47954,47954
  • 47954 - Cyclin-like
  • 47954 - Cyclin-like
  • 0.0242Inherited
    54236,47031
  • 54236 - Ubiquitin-like
  • 47031 - Second domain of FERM
  • 0.03509Inherited
    47031,50729
  • 47031 - Second domain of FERM
  • 50729 - PH domain-like
  • 0.06466Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    57440,57440,57440
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 0.01234Inherited
    54236,47031,50729
  • 54236 - Ubiquitin-like
  • 47031 - Second domain of FERM
  • 50729 - PH domain-like
  • 0.03509Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
    (show help)