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Disease Ontology (DO): lipid metabolism disorder

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Root: DO Hierarchy (disease ontology from University of Maryland)

Shortest distance to current term (+ for parents, - for children) DO term [DO ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + 3:   disease [DOID:4] <8>
+ + 2:   disease of metabolism [DOID:0014667] <2>(22|34) (27|12|5)
+ 1:   inherited metabolic disorder [DOID:655] <18>(12|15) (16|5|0)
0:   lipid metabolism disorder [DOID:3146] <13>(3|8) (7|3|0)
- 1:   familial hyperlipidemia [DOID:1168] <6>(3|8) (7|3|0)
- 1:   hypolipoproteinemia [DOID:1387] <4>(0|0) (0|0|0)
- 1:   steroid inherited metabolic disorder [DOID:1701] <3>(0|0) (0|0|0)
- 1:   Barth syndrome [DOID:0050476](0|0) (0|0|0)
- 1:   Refsum disease [DOID:10582](0|0) (0|0|0)
- 1:   Smith-Lemli-Opitz syndrome [DOID:14692](0|0) (0|0|0)
- 1:   carnitine palmitoyltransferase I deficiency [DOID:0090129](0|0) (0|0|0)
- 1:   carnitine palmitoyltransferase II deficiency [DOID:0060235](0|0) (0|0|0)
- 1:   chylomicron retention disease [DOID:0060357](0|0) (0|0|0)
- 1:   lipoid proteinosis [DOID:14498](0|0) (0|0|0)
- 1:   medium chain acyl-CoA dehydrogenase deficiency [DOID:0080153](0|0) (0|0|0)
- 1:   short chain acyl-CoA dehydrogenase deficiency [DOID:0080154](0|0) (0|0|0)
- 1:   very long chain acyl-CoA dehydrogenase deficiency [DOID:0080155](0|0) (0|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
Apolipoprotein A-I0Direct
PGBD-like0.0008098Direct
Nuclear receptor ligand-binding domain0.04565Inherited


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Family

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SCOP termFDR (all)Annotation (direct or inherited)
Apolipoprotein A-I0Direct
Long-chain cytokines0.0001063Direct
Fatty acid binding protein-like0.0001487Direct
MMP N-terminal domain0.0005458Direct
Matrix metalloproteases, catalytic domain0.0009639Direct
Hemopexin-like domain0.001147Inherited
Nuclear receptor ligand-binding domain0.03598Inherited
Nuclear receptor0.03598Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Apolipoprotein A-I0Direct
PGBD-like0.0005028Direct
Hemopexin-like domain0.001077Inherited
4-helical cytokines0.001373Inherited
Lipocalins0.01592Inherited
Kringle-like0.01592Inherited
Nuclear receptor ligand-binding domain0.03457Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
47090,55486
  • 47090 - PGBD-like
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 0.0005028Direct
    57440,57440
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 0.01592Inherited
    57716,48508
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 48508 - Nuclear receptor ligand-binding domain
  • 0.01854Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
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