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Disease Ontology (DO): bone inflammation disease

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Root: DO Hierarchy (disease ontology from University of Maryland)

Shortest distance to current term (+ for parents, - for children) DO term [DO ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + + 5:   disease [DOID:4] <8>
+ + + + 4:   disease of anatomical entity [DOID:7] <12>(143|187) (147|103|58)
+ + + 3:   musculoskeletal system disease [DOID:17] <3>(29|42) (37|17|6)
+ + 2:   connective tissue disease [DOID:65] <22>(23|31) (28|11|4)
+ 1:   bone disease [DOID:0080001] <5>(19|22) (24|8|3)
0:   bone inflammation disease [DOID:3342] <8>(15|16) (18|6|1)
- 1:   arthropathy [DOID:381] <18>(5|6) (6|2|0)
- 1:   arthritis [DOID:848] <7>(10|11) (12|5|1)
- 1:   osteomyelitis [DOID:1019] <2>(0|0) (0|0|0)
- 1:   Caffey disease [DOID:4257](0|0) (0|0|0)
- 1:   Osgood-Schlatter's disease [DOID:7489](0|0) (0|0|0)
- 1:   ankylosing spondylitis [DOID:7147](0|0) (0|0|0)
- 1:   epicondylitis [DOID:14087](0|0) (0|0|0)
- 1:   mastoiditis [DOID:0060322](0|0) (0|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
TNF receptor-like0.0000000000001691Direct
Interleukin 8-like chemokines0.00000001692Direct
MHC antigen-recognition domain0.0000009002Direct
TNF-like0.000004061Direct
DEATH domain0.000008237Direct
Toll/Interleukin receptor TIR domain0.0001751Direct
TIMP-like0.0006994Direct
RNI-like0.0008464Direct
Hemopexin-like domain0.001002Inherited
PRTase-like0.001095Inherited
PGBD-like0.001101Inherited
4-helical cytokines0.08494Inherited
FnI-like domain0.2558Inherited
TSP-1 type 1 repeat0.4076Inherited
Cystine-knot cytokines0.7911Inherited


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Family

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SCOP termFDR (all)Annotation (direct or inherited)
TNF receptor-like0.000000000002282Direct
Interleukin 8-like chemokines0.00000001724Direct
C1 set domains (antibody constant domain-like)0.00000009768Direct
MHC antigen-recognition domain0.0000008333Direct
TNF-like0.000003679Direct
Toll/Interleukin receptor TIR domain0.00009403Direct
Short-chain cytokines0.0001011Direct
Interleukin-1 (IL-1)0.0002396Direct
C2 set domains0.0005714Direct
Tissue inhibitor of metalloproteinases, TIMP0.0007944Direct
Hemopexin-like domain0.0008238Direct
MMP N-terminal domain0.0008896Direct
C-type lectin domain0.004977Inherited
Interferons/interleukin-10 (IL-10)0.007326Inherited
Transforming growth factor (TGF)-beta0.244Inherited
TSP-1 type 1 repeat0.3491Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
TNF receptor-like0.00000000000007536Direct
Interleukin 8-like chemokines0.000000007983Direct
MHC antigen-recognition domain0.0000004618Direct
TNF-like0.000002175Direct
DEATH domain0.000004508Direct
Toll/Interleukin receptor TIR domain0.0001039Direct
TIMP-like0.0004303Direct
RNI-like0.0005273Direct
Hemopexin-like domain0.0006291Direct
PRTase-like0.0006921Direct
PGBD-like0.000695Direct
4-helical cytokines0.06677Inherited
FnI-like domain0.215Inherited
Family A G protein-coupled receptor-like0.2376Inherited
TSP-1 type 1 repeat0.3531Inherited
MFS general substrate transporter0.363Inherited
Cytokine0.381Inherited
Cystine-knot cytokines0.7189Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
57586,57586
  • 57586 - TNF receptor-like
  • 57586 - TNF receptor-like
  • 0.000000000009543Direct
    54452,48726
  • 54452 - MHC antigen-recognition domain
  • 48726 - Immunoglobulin
  • 0.00000007392Direct
    57184,57603
  • 57184 - Growth factor receptor domain
  • 57603 - FnI-like domain
  • 0.00009184Direct
    57440,57440
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 0.0004586Direct
    57603,82895
  • 57603 - FnI-like domain
  • 82895 - TSP-1 type 1 repeat
  • 0.0006921Direct
    47090,55486
  • 47090 - PGBD-like
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 0.000695Direct

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    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    57586,57586,57586
  • 57586 - TNF receptor-like
  • 57586 - TNF receptor-like
  • 57586 - TNF receptor-like
  • 0.000008594Direct


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
    (show help)