SUPERFAMILY 1.75 HMM library and genome assignments server

Superfamily is undergoing a server migration - you are now browsing on the new server. Please contact us if you experience any problems.

Disease Ontology (DO): liver cancer

(show info)

Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Root: DO Hierarchy (disease ontology from University of Maryland)

Shortest distance to current term (+ for parents, - for children) DO term [DO ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + + 5:   disease [DOID:4] <8>
+ + + + 4:   disease of cellular proliferation [DOID:14566] <3>(123|191) (129|118|56)
+ + + 3:   cancer [DOID:162] <2>(115|181) (120|113|54)
+ + 2:   organ system cancer [DOID:0050686] <14>(66|106) (72|58|31)
+ 1:   gastrointestinal system cancer [DOID:3119] <14>(12|23) (14|20|8)
0:   liver cancer [DOID:3571] <4>(5|7) (6|5|1)
- 1:   liver sarcoma [DOID:270] <4>(0|0) (0|0|0)
- 1:   hepatoblastoma [DOID:687] <2>(0|0) (0|0|0)
- 1:   liver carcinoma [DOID:686] <1>(5|7) (6|5|1)
- 1:   liver lymphoma [DOID:901](0|0) (0|0|0)


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Superfamily

(show details)
SCOP termFDR (all)Annotation (direct or inherited)
p53 tetramerization domain0Direct
Notch domain0.0003867Direct
PGBD-like0.1057Inherited
Growth factor receptor domain0.1785Inherited
Protein kinase-like (PK-like)0.6996Inherited


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Family

(show details)
SCOP termFDR (all)Annotation (direct or inherited)
p53 tetramerization domain0Direct
p53 DNA-binding domain-like0Direct
Notch domain0.0002734Direct
Growth factor receptor domain0.03624Inherited
MMP N-terminal domain0.0843Inherited
Platelet-derived growth factor-like0.0887Inherited
Protein kinases, catalytic subunit0.7111Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
Plot tree as:   Download Newick format tree:
(show help)

Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

(show details)
Supra-domain (Single) FDR (all) Annotation (direct or inherited)
p53 tetramerization domain0Direct
Notch domain0.0002362Direct
MHC antigen-recognition domain0.02849Inherited
PGBD-like0.08422Inherited
Growth factor receptor domain0.1461Inherited
Protein kinase-like (PK-like)0.6281Inherited

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
49417,47719
  • 49417 - p53-like transcription factors
  • 47719 - p53 tetramerization domain
  • 0Direct
    90193,90193
  • 90193 - Notch domain
  • 90193 - Notch domain
  • 0Direct
    57196,90193
  • 57196 - EGF/Laminin
  • 90193 - Notch domain
  • 0Direct
    57586,57586
  • 57586 - TNF receptor-like
  • 57586 - TNF receptor-like
  • 0.02483Inherited
    47090,55486
  • 47090 - PGBD-like
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 0.08422Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    57196,57196,90193
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 90193 - Notch domain
  • 0Direct


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
    (show help)