SUPERFAMILY 1.75 HMM library and genome assignments server

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Disease Ontology (DO): non-small cell lung carcinoma

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Root: DO Hierarchy (disease ontology from University of Maryland)

Shortest distance to current term (+ for parents, - for children) DO term [DO ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + + + + 7:   disease [DOID:4] <8>
+ + + + + + 6:   disease of cellular proliferation [DOID:14566] <3>(123|191) (129|118|56)
+ + + + + 5:   cancer [DOID:162] <2>(115|181) (120|113|54)
+ + + + 4:   organ system cancer [DOID:0050686] <14>(66|106) (72|58|31)
+ + + 3:   respiratory system cancer [DOID:0050615] <6>(8|12) (9|7|2)
+ + 2:   lung cancer [DOID:1324] <10>(6|10) (7|6|2)
+ 1:   lung carcinoma [DOID:3905] <6>(6|10) (7|6|2)
0:   non-small cell lung carcinoma [DOID:3908] <4>(3|6) (4|5|2)
- 1:   lung adenocarcinoma [DOID:3910] <5>(1|2) (1|1|0)
- 1:   lung large cell carcinoma [DOID:4556] <5>(2|1) (2|1|0)
- 1:   lung squamous cell carcinoma [DOID:3907] <2>(0|0) (0|0|0)
- 1:   adenosquamous cell lung carcinoma [DOID:4829](0|0) (0|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
p53 tetramerization domain0Direct
Prefoldin0.06575Inherited
Intermediate filament protein, coiled coil region0.9591Inherited


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Family

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SCOP termFDR (all)Annotation (direct or inherited)
p53 DNA-binding domain-like0Direct
p53 tetramerization domain0Direct
S100 proteins0.00002786Direct
L domain0.00006133Direct
Platelet-derived growth factor-like0.0003748Direct
Intermediate filament protein, coiled coil region0.9348Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
p53 tetramerization domain0Direct
4-helical cytokines0.0007998Direct
Prefoldin0.05083Inherited
Intermediate filament protein, coiled coil region0.8907Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
49417,47719
  • 49417 - p53-like transcription factors
  • 47719 - p53 tetramerization domain
  • 0Direct
    57184,52058
  • 57184 - Growth factor receptor domain
  • 52058 - L domain-like
  • 0.00004638Direct
    52058,57184
  • 52058 - L domain-like
  • 57184 - Growth factor receptor domain
  • 0.00004638Direct
    57184,57603
  • 57184 - Growth factor receptor domain
  • 57603 - FnI-like domain
  • 0.0004613Direct
    46579,64593
  • 46579 - Prefoldin
  • 64593 - Intermediate filament protein, coiled coil region
  • 0.00377Inherited

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    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    52058,57184,52058
  • 52058 - L domain-like
  • 57184 - Growth factor receptor domain
  • 52058 - L domain-like
  • 0.00004638Direct
    57184,52058,57184
  • 57184 - Growth factor receptor domain
  • 52058 - L domain-like
  • 57184 - Growth factor receptor domain
  • 0.0001166Direct


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
    (show help)