SUPERFAMILY 1.75 HMM library and genome assignments server

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Disease Ontology (DO): pancreatic adenocarcinoma

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Root: DO Hierarchy (disease ontology from University of Maryland)

Shortest distance to current term (+ for parents, - for children) DO term [DO ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + + + + 7:   disease [DOID:4] <8>
+ + + + + + 6:   disease of cellular proliferation [DOID:14566] <3>(123|191) (129|118|56)
+ + + + + 5:   cancer [DOID:162] <2>(115|181) (120|113|54)
+ + + + 4:   organ system cancer [DOID:0050686] <14>(66|106) (72|58|31)
+ + + 3:   endocrine gland cancer [DOID:170] <7>(7|15) (8|12|3)
+ + 2:   pancreatic cancer [DOID:1793] <5>(4|7) (5|10|3)
+ 1:   pancreatic carcinoma [DOID:4905] <4>(4|6) (5|10|3)
0:   pancreatic adenocarcinoma [DOID:4074] <5>(4|6) (5|10|3)
- 1:   pancreatic ductal adenocarcinoma [DOID:3498] <5>(3|4) (4|6|2)
- 1:   pancreatic cystadenocarcinoma [DOID:4073] <3>(0|0) (0|0|0)
- 1:   pancreatic intraductal papillary-colloid carcinoma [DOID:7574] <2>(0|0) (0|0|0)
- 1:   pancreatic acinar cell adenocarcinoma [DOID:5742](0|0) (0|0|0)
- 1:   pancreatic foamy gland adenocarcinoma [DOID:7577](0|0) (0|0|0)


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
TNF receptor-like0.0001306Direct
Kringle-like0.001308Inherited
PGBD-like0.004171Inherited
Galactose-binding domain-like0.1858Inherited


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Family

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SCOP termFDR (all)Annotation (direct or inherited)
TNF receptor-like0.00004836Direct
L domain0.00005667Direct
Kringle modules0.001746Inherited
MMP N-terminal domain0.003386Inherited
Eukaryotic proteases0.1485Inherited
Ephrin receptor ligand binding domain0.1983Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
TNF receptor-like0.00007747Direct
Kringle-like0.0008319Direct
PGBD-like0.002808Inherited
Trypsin-like serine proteases0.1525Inherited
Galactose-binding domain-like0.1525Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
50729,56112
  • 50729 - PH domain-like
  • 56112 - Protein kinase-like (PK-like)
  • 0.000004511Direct
    57586,57586
  • 57586 - TNF receptor-like
  • 57586 - TNF receptor-like
  • 0.0000242Direct
    57184,52058
  • 57184 - Growth factor receptor domain
  • 52058 - L domain-like
  • 0.00004311Direct
    52058,57184
  • 52058 - L domain-like
  • 57184 - Growth factor receptor domain
  • 0.00004311Direct
    57440,50494
  • 57440 - Kringle-like
  • 50494 - Trypsin-like serine proteases
  • 0.0002603Direct
    57440,57440
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 0.0002603Direct
    47090,55486
  • 47090 - PGBD-like
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 0.002808Inherited
    56112,47769
  • 56112 - Protein kinase-like (PK-like)
  • 47769 - SAM/Pointed domain
  • 0.2012Inherited
    49785,57184
  • 49785 - Galactose-binding domain-like
  • 57184 - Growth factor receptor domain
  • 0.2648Inherited
    57184,49265
  • 57184 - Growth factor receptor domain
  • 49265 - Fibronectin type III
  • 0.3459Inherited

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    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    52058,57184,52058
  • 52058 - L domain-like
  • 57184 - Growth factor receptor domain
  • 52058 - L domain-like
  • 0.00004311Direct
    57586,57586,57586
  • 57586 - TNF receptor-like
  • 57586 - TNF receptor-like
  • 57586 - TNF receptor-like
  • 0.0001584Direct
    49785,57184,49265
  • 49785 - Galactose-binding domain-like
  • 57184 - Growth factor receptor domain
  • 49265 - Fibronectin type III
  • 0.3459Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
    (show help)