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Disease Ontology (DO): liver disease

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Root: DO Hierarchy (disease ontology from University of Maryland)

Shortest distance to current term (+ for parents, - for children) DO term [DO ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + 4:   disease [DOID:4] <8>
+ + + 3:   disease of anatomical entity [DOID:7] <12>(143|187) (147|103|58)
+ + 2:   gastrointestinal system disease [DOID:77] <14>(33|43) (35|18|5)
+ 1:   hepatobiliary disease [DOID:3118] <2>(8|11) (8|6|1)
0:   liver disease [DOID:409] <8>(8|10) (8|6|1)
- 1:   hepatitis [DOID:2237] <4>(1|4) (1|0|0)
- 1:   liver cirrhosis [DOID:5082] <2>(5|3) (5|3|1)
- 1:   Alagille syndrome [DOID:9245](0|0) (0|0|0)
- 1:   Wilson disease [DOID:893](0|0) (0|0|0)
- 1:   hepatopulmonary syndrome [DOID:900](0|0) (0|0|0)
- 1:   hepatorenal syndrome [DOID:11823](0|0) (0|0|0)
- 1:   intrahepatic cholestasis [DOID:1852](2|4) (2|2|0)
- 1:   liver inflammatory pseudotumor [DOID:918](0|0) (0|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex0Direct
MHC antigen-recognition domain0.00000002116Direct
Toll/Interleukin receptor TIR domain0.00007379Direct
Kringle-like0.0006886Direct
CoA-dependent acyltransferases0.002256Inherited
Insulin-like0.005829Inherited
Single hybrid motif0.01052Inherited
ABC transporter transmembrane region0.8946Inherited


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Family

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SCOP termFDR (all)Annotation (direct or inherited)
MHC antigen-recognition domain0.00000002503Direct
C1 set domains (antibody constant domain-like)0.00000002503Direct
Toll/Interleukin receptor TIR domain0.00004433Direct
C5 cytosine-specific DNA methylase, DCM0.0005812Direct
Interferons/interleukin-10 (IL-10)0.0008238Direct
Interleukin-1 (IL-1)0.001873Inherited
Insulin-like0.004786Inherited
Biotinyl/lipoyl-carrier proteins and domains0.008841Inherited
ABC transporter ATPase domain-like0.8657Inherited
ABC transporter transmembrane region0.8657Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex0Direct
MHC antigen-recognition domain0.00000001006Direct
Toll/Interleukin receptor TIR domain0.00004314Direct
Kringle-like0.0004226Direct
CoA-dependent acyltransferases0.001482Inherited
Insulin-like0.003998Inherited
Single hybrid motif0.007362Inherited
ABC transporter transmembrane region0.8227Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
47005,52777
  • 47005 - Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex
  • 52777 - CoA-dependent acyltransferases
  • 0Direct
    51230,47005
  • 51230 - Single hybrid motif
  • 47005 - Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex
  • 0Direct
    54452,48726
  • 54452 - MHC antigen-recognition domain
  • 48726 - Immunoglobulin
  • 0.000000016Direct
    57440,57440
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 0.00001524Direct
    57440,50494
  • 57440 - Kringle-like
  • 50494 - Trypsin-like serine proteases
  • 0.000258Direct
    90123,52540
  • 90123 - ABC transporter transmembrane region
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.8227Inherited

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    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    51230,47005,52777
  • 51230 - Single hybrid motif
  • 47005 - Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex
  • 52777 - CoA-dependent acyltransferases
  • 0Direct


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
    (show help)