SUPERFAMILY 1.75 HMM library and genome assignments server

Superfamily is undergoing a server migration - you are now browsing on the new server. Please contact us if you experience any problems.

Disease Ontology (DO): thoracic cancer

(show info)

Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Root: DO Hierarchy (disease ontology from University of Maryland)

Shortest distance to current term (+ for parents, - for children) DO term [DO ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + 4:   disease [DOID:4] <8>
+ + + 3:   disease of cellular proliferation [DOID:14566] <3>(123|191) (129|118|56)
+ + 2:   cancer [DOID:162] <2>(115|181) (120|113|54)
+ 1:   organ system cancer [DOID:0050686] <14>(66|106) (72|58|31)
0:   thoracic cancer [DOID:5093] <3>(10|17) (13|12|7)
- 1:   breast cancer [DOID:1612] <18>(10|17) (13|12|7)
- 1:   mediastinal cancer [DOID:5559] <8>(0|0) (0|0|0)
- 1:   chest wall lymphoma [DOID:6758](0|0) (0|0|0)


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Superfamily

(show details)
SCOP termFDR (all)Annotation (direct or inherited)
Protein kinase-like (PK-like)0.00001539Direct
Metalloproteases ("zincins"), catalytic domain0.002594Inherited
Integrin domains0.003972Inherited
TNF receptor-like0.01512Inherited
PGBD-like0.01551Inherited
SAM/Pointed domain0.01577Inherited
p53-like transcription factors0.02862Inherited
Kringle-like0.06461Inherited
SH2 domain0.06739Inherited
Nuclear receptor ligand-binding domain0.4738Inherited


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Family

(show details)
SCOP termFDR (all)Annotation (direct or inherited)
Long-chain cytokines0.0001552Direct
Protein kinases, catalytic subunit0.0001987Direct
L domain0.0004547Direct
Uteroglobin-like0.0004658Direct
Reprolysin-like0.001962Inherited
TNF receptor-like0.003556Inherited
Integrin domains0.003556Inherited
Pointed domain0.006561Inherited
PB1 domain0.006561Inherited
S100 proteins0.007564Inherited
Ephrin receptor ligand binding domain0.01321Inherited
MMP N-terminal domain0.01392Inherited
SAM (sterile alpha motif) domain0.02941Inherited
Blood coagulation inhibitor (disintegrin)0.03156Inherited
Kringle modules0.1564Inherited
Nuclear receptor0.4114Inherited
Nuclear receptor ligand-binding domain0.4785Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
Plot tree as:   Download Newick format tree:
(show help)

Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

(show details)
Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Protein kinase-like (PK-like)0.00000854Direct
Uteroglobin-like0.001367Inherited
Metalloproteases ("zincins"), catalytic domain0.001711Inherited
Integrin domains0.002669Inherited
TNF receptor-like0.01073Inherited
PGBD-like0.01101Inherited
SAM/Pointed domain0.01121Inherited
p53-like transcription factors0.02115Inherited
Blood coagulation inhibitor (disintegrin)0.02626Inherited
Kringle-like0.04989Inherited
SH2 domain0.05218Inherited
BRCT domain0.07688Inherited
Nuclear receptor ligand-binding domain0.4149Inherited

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
57184,52058
  • 57184 - Growth factor receptor domain
  • 52058 - L domain-like
  • 0.0003521Direct
    52058,57184
  • 52058 - L domain-like
  • 57184 - Growth factor receptor domain
  • 0.0003521Direct
    103575,81296
  • 103575 - Plexin repeat
  • 81296 - E set domains
  • 0.0003651Direct
    57586,57586
  • 57586 - TNF receptor-like
  • 57586 - TNF receptor-like
  • 0.002669Inherited
    49785,57184
  • 49785 - Galactose-binding domain-like
  • 57184 - Growth factor receptor domain
  • 0.009055Inherited
    56112,47769
  • 56112 - Protein kinase-like (PK-like)
  • 47769 - SAM/Pointed domain
  • 0.01062Inherited
    47090,55486
  • 47090 - PGBD-like
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 0.01101Inherited
    50729,56112
  • 50729 - PH domain-like
  • 56112 - Protein kinase-like (PK-like)
  • 0.013Inherited
    57184,49265
  • 57184 - Growth factor receptor domain
  • 49265 - Fibronectin type III
  • 0.01802Inherited
    57440,57440
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 0.02484Inherited
    55486,57552
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 57552 - Blood coagulation inhibitor (disintegrin)
  • 0.02626Inherited
    57440,50494
  • 57440 - Kringle-like
  • 50494 - Trypsin-like serine proteases
  • 0.0653Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    57184,52058,57184
  • 57184 - Growth factor receptor domain
  • 52058 - L domain-like
  • 57184 - Growth factor receptor domain
  • 0Direct
    52058,57184,52058
  • 52058 - L domain-like
  • 57184 - Growth factor receptor domain
  • 52058 - L domain-like
  • 0.0003521Direct
    103575,81296,81296
  • 103575 - Plexin repeat
  • 81296 - E set domains
  • 81296 - E set domains
  • 0.0003651Direct
    81296,81296,81296
  • 81296 - E set domains
  • 81296 - E set domains
  • 81296 - E set domains
  • 0.002084Inherited
    49785,57184,49265
  • 49785 - Galactose-binding domain-like
  • 57184 - Growth factor receptor domain
  • 49265 - Fibronectin type III
  • 0.005728Inherited
    69179,69179,69179
  • 69179 - Integrin domains
  • 69179 - Integrin domains
  • 69179 - Integrin domains
  • 0.006017Inherited
    57586,57586,57586
  • 57586 - TNF receptor-like
  • 57586 - TNF receptor-like
  • 57586 - TNF receptor-like
  • 0.013Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
    (show help)