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Disease Ontology (DO): eye disease

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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Root: DO Hierarchy (disease ontology from University of Maryland)

Shortest distance to current term (+ for parents, - for children) DO term [DO ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + + 5:   disease [DOID:4] <8>
+ + + + 4:   disease of anatomical entity [DOID:7] <12>(143|187) (147|103|58)
+ + + 3:   nervous system disease [DOID:863] <11>(51|61) (54|28|13)
+ + 2:   sensory system disease [DOID:0050155] <2>(16|13) (17|5|2)
+ 1:   eye and adnexa disease [DOID:1492] <3>(13|11) (14|5|2)
0:   eye disease [DOID:5614] <34>(13|11) (14|5|2)
- 1:   retinal disease [DOID:5679] <20>(3|1) (4|2|1)
- 1:   corneal disease [DOID:10124] <17>(0|2) (0|0|0)
- 1:   lacrimal apparatus disease [DOID:1400] <16>(1|0) (1|0|0)
- 1:   glaucoma [DOID:1686] <11>(2|2) (2|0|0)
- 1:   microphthalmia [DOID:10629] <8>(0|0) (0|0|0)
- 1:   fundus dystrophy [DOID:8501] <7>(0|0) (0|0|0)
- 1:   refractive error [DOID:9835] <7>(5|4) (5|2|1)
- 1:   conjunctival disease [DOID:4251] <6>(0|0) (0|0|0)
- 1:   eye degenerative disease [DOID:9799] <6>(0|0) (0|0|0)
- 1:   globe disease [DOID:1242] <5>(0|0) (0|0|0)
- 1:   keratoconjunctivitis [DOID:9368] <5>(0|0) (0|0|0)
- 1:   scleral disease [DOID:11343] <5>(0|0) (0|0|0)
- 1:   visual pathway disease [DOID:1393] <5>(0|0) (0|0|0)
- 1:   eye accommodation disease [DOID:10034] <4>(0|0) (0|0|0)
- 1:   amblyopia [DOID:10376] <3>(0|0) (0|0|0)
- 1:   chorioretinitis [DOID:8886] <3>(0|0) (0|0|0)
- 1:   lens disease [DOID:110] <3>(1|1) (1|0|0)
- 1:   uveal disease [DOID:3480] <3>(2|2) (2|1|0)
- 1:   ocular hypotension [DOID:790] <2>(0|0) (0|0|0)
- 1:   pupil disease [DOID:238] <2>(0|0) (0|0|0)
- 1:   ptosis [DOID:0060260] <1>(0|0) (0|0|0)
- 1:   Aland Island eye disease [DOID:0050630](0|0) (0|0|0)
- 1:   Cogan syndrome [DOID:0060216](0|0) (0|0|0)
- 1:   Cogan-Reese syndrome [DOID:0060217](0|0) (0|0|0)
- 1:   anterior segment mesenchymal dysgenesis [DOID:0060605](0|0) (0|0|0)
- 1:   asthenopia [DOID:10141](0|0) (0|0|0)
- 1:   coloboma [DOID:12270](0|0) (0|0|0)
- 1:   exophthalmos [DOID:9370](0|0) (0|0|0)
- 1:   neuroretinitis [DOID:10176](0|0) (0|0|0)
- 1:   ocular albinism [DOID:0050633](0|0) (0|0|0)
- 1:   ocular hypertension [DOID:9282](0|0) (0|0|0)
- 1:   ophthalmia nodosa [DOID:9722](0|0) (0|0|0)
- 1:   pigment dispersion syndrome [DOID:0060680](0|0) (0|0|0)
- 1:   scotoma [DOID:9335](0|0) (0|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
gamma-Crystallin-like0.0000000001561Direct
Complement control module/SCR domain0.0003852Direct
TNF-like0.005864Inherited
PGBD-like0.006331Inherited
L domain-like0.01022Inherited
4-helical cytokines0.01292Inherited
TIMP-like0.02126Inherited
Metalloproteases ("zincins"), catalytic domain0.02835Inherited
Hemopexin-like domain0.05358Inherited
Kringle-like0.06205Inherited
MHC antigen-recognition domain0.06292Inherited
Cytokine0.09187Inherited
RNI-like0.09187Inherited


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Family

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SCOP termFDR (all)Annotation (direct or inherited)
Crystallins/Ca-binding development proteins0.0000000001483Direct
Complement control module/SCR domain0.0004115Direct
Ngr ectodomain-like0.002218Inherited
TNF-like0.005535Inherited
MMP N-terminal domain0.005596Inherited
Interleukin-1 (IL-1)0.00805Inherited
Matrix metalloproteases, catalytic domain0.01198Inherited
Hemopexin-like domain0.05034Inherited
Transforming growth factor (TGF)-beta0.0539Inherited
MHC antigen-recognition domain0.06102Inherited
C1 set domains (antibody constant domain-like)0.06102Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
Plot tree as:   Download Newick format tree:
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
gamma-Crystallin-like0.00000000007207Direct
Complement control module/SCR domain0.0002352Direct
TNF-like0.004018Inherited
PGBD-like0.004341Inherited
L domain-like0.007145Inherited
4-helical cytokines0.009129Inherited
TIMP-like0.01543Inherited
Metalloproteases ("zincins"), catalytic domain0.02095Inherited
Hemopexin-like domain0.04091Inherited
Kringle-like0.04777Inherited
MHC antigen-recognition domain0.04848Inherited
RNI-like0.07261Inherited
Cytokine0.07261Inherited
Trypsin-like serine proteases0.1175Inherited

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
57535,57535
  • 57535 - Complement control module/SCR domain
  • 57535 - Complement control module/SCR domain
  • 0.0005545Direct
    57440,57440
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 0.001252Inherited
    47090,55486
  • 47090 - PGBD-like
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 0.004341Inherited
    54452,48726
  • 54452 - MHC antigen-recognition domain
  • 48726 - Immunoglobulin
  • 0.03244Inherited
    49899,49899
  • 49899 - Concanavalin A-like lectins/glucanases
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.06378Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    57535,57535,57535
  • 57535 - Complement control module/SCR domain
  • 57535 - Complement control module/SCR domain
  • 57535 - Complement control module/SCR domain
  • 0.0002161Direct
    57440,57440,57440
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 0.0021Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
    (show help)