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Disease Ontology (DO): hereditary breast ovarian cancer syndrome

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Root: DO Hierarchy (disease ontology from University of Maryland)

Shortest distance to current term (+ for parents, - for children) DO term [DO ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + + 5:   disease [DOID:4] <8>
+ + + + 4:   genetic disease [DOID:630] <11>(19|28) (22|16|7)
+ + + 3:   monogenic disease [DOID:0050177] <7>(17|25) (19|14|6)
+ + 2:   autosomal genetic disease [DOID:0050739] <8>(17|24) (19|14|6)
+ 1:   autosomal dominant disease [DOID:0050736] <79>(7|13) (9|8|3)
0:   hereditary breast ovarian cancer syndrome [DOID:5683](4|10) (4|8|3)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
p53 tetramerization domain0Direct
BRCT domain0.00000000000009498Direct
Nuclear receptor coactivator interlocking domain0.0000009963Direct
UBC-like0.000381Direct


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Family

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SCOP termFDR (all)Annotation (direct or inherited)
p53 tetramerization domain0Direct
p53 DNA-binding domain-like0Direct
Nuclear receptor coactivator interlocking domain0.0000006901Direct
L domain0.000003598Direct
RecA protein-like (ATPase-domain)0.00002391Direct
Single strand DNA-binding domain, SSB0.00006591Direct
DNA gyrase/MutL, N-terminal domain0.0001629Direct
DNA gyrase/MutL, second domain0.0001629Direct
FHA domain0.0004942Direct
UBC-related0.0009129Direct


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
p53 tetramerization domain0Direct
BRCT domain0.00000000000004217Direct
Nuclear receptor coactivator interlocking domain0.0000005112Direct
UBC-like0.0002318Direct

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
49417,47719
  • 49417 - p53-like transcription factors
  • 47719 - p53 tetramerization domain
  • 0Direct
    52113,52113
  • 52113 - BRCT domain
  • 52113 - BRCT domain
  • 0Direct
    57184,52058
  • 57184 - Growth factor receptor domain
  • 52058 - L domain-like
  • 0.000002719Direct
    52058,57184
  • 52058 - L domain-like
  • 57184 - Growth factor receptor domain
  • 0.000002719Direct
    47459,55785
  • 47459 - HLH, helix-loop-helix DNA-binding domain
  • 55785 - PYP-like sensor domain (PAS domain)
  • 0.00004409Direct
    55874,54211
  • 55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
  • 54211 - Ribosomal protein S5 domain 2-like
  • 0.0002744Direct
    54928,54928
  • 54928 - RNA-binding domain, RBD
  • 54928 - RNA-binding domain, RBD
  • 0.0007744Direct
    55785,55785
  • 55785 - PYP-like sensor domain (PAS domain)
  • 55785 - PYP-like sensor domain (PAS domain)
  • 0.0008057Direct

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    52058,57184,52058
  • 52058 - L domain-like
  • 57184 - Growth factor receptor domain
  • 52058 - L domain-like
  • 0.000002719Direct
    57184,52058,57184
  • 57184 - Growth factor receptor domain
  • 52058 - L domain-like
  • 57184 - Growth factor receptor domain
  • 0.00001274Direct
    47459,55785,55785
  • 47459 - HLH, helix-loop-helix DNA-binding domain
  • 55785 - PYP-like sensor domain (PAS domain)
  • 55785 - PYP-like sensor domain (PAS domain)
  • 0.0004923Direct


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
    (show help)