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Disease Ontology (DO): muscle tissue disease

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Root: DO Hierarchy (disease ontology from University of Maryland)

Shortest distance to current term (+ for parents, - for children) DO term [DO ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + 4:   disease [DOID:4] <8>
+ + + 3:   disease of anatomical entity [DOID:7] <12>(143|187) (147|103|58)
+ + 2:   musculoskeletal system disease [DOID:17] <3>(29|42) (37|17|6)
+ 1:   muscular disease [DOID:0080000] <2>(9|13) (12|7|3)
0:   muscle tissue disease [DOID:66] <5>(8|12) (11|7|3)
- 1:   myopathy [DOID:423] <23>(6|9) (7|6|2)
- 1:   distal arthrogryposis [DOID:0050646](0|0) (0|0|0)
- 1:   myostatin-related muscle hypertrophy [DOID:0111072](0|0) (0|0|0)
- 1:   myotonia congenita [DOID:2106](0|0) (0|0|0)
- 1:   rippling muscle disease 2 [DOID:0060255](0|0) (0|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
Spectrin repeat0.0001095Direct
Calpain large subunit, middle domain (domain III)0.0001417Direct
4-helical cytokines0.0002065Direct
Toll/Interleukin receptor TIR domain0.005906Inherited
RNA-binding domain, RBD0.01924Inherited
Kringle-like0.03224Inherited
PH domain-like0.8863Inherited
PGBD-like0.9526Inherited


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Family

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SCOP termFDR (all)Annotation (direct or inherited)
Spectrin repeat0.00009531Direct
Calpain large subunit, middle domain (domain III)0.0001087Direct
Calpain large subunit, catalytic domain (domain II)0.0001087Direct
Penta-EF-hand proteins0.0005458Direct
Interferons/interleukin-10 (IL-10)0.0008961Direct
MIR domain0.0009511Direct
FAD-linked reductases, N-terminal domain0.0009511Direct
EF-hand modules in multidomain proteins0.002243Inherited
Toll/Interleukin receptor TIR domain0.004125Inherited
Canonical RBD0.0094Inherited
MMP N-terminal domain0.9291Inherited
Matrix metalloproteases, catalytic domain0.9291Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Spectrin repeat0.00006435Direct
Calpain large subunit, middle domain (domain III)0.00008419Direct
4-helical cytokines0.0001238Direct
Calponin-homology domain, CH-domain0.0007185Direct
MIR domain0.0007775Direct
Toll/Interleukin receptor TIR domain0.004047Inherited
RNA-binding domain, RBD0.01391Inherited
EF-hand0.02352Inherited
Kringle-like0.02404Inherited
PH domain-like0.8143Inherited
PGBD-like0.8839Inherited

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
47473,57850
  • 47473 - EF-hand
  • 57850 - RING/U-box
  • 0Direct
    49758,47473
  • 49758 - Calpain large subunit, middle domain (domain III)
  • 47473 - EF-hand
  • 0Direct
    46966,46966
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 0.00001455Direct
    53300,53300
  • 53300 - vWA-like
  • 53300 - vWA-like
  • 0.00001524Direct
    57440,57440
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 0.001246Inherited
    47473,47473
  • 47473 - EF-hand
  • 47473 - EF-hand
  • 0.007487Inherited
    47090,55486
  • 47090 - PGBD-like
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 0.8839Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    47473,47473,57850
  • 47473 - EF-hand
  • 47473 - EF-hand
  • 57850 - RING/U-box
  • 0Direct
    46966,46966,46966
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 0.00000564Direct
    57440,57440,57440
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 0.0002134Direct


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
    (show help)