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Disease Ontology (DO): lymphatic system disease

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Root: DO Hierarchy (disease ontology from University of Maryland)

Shortest distance to current term (+ for parents, - for children) DO term [DO ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + 3:   disease [DOID:4] <8>
+ + 2:   disease of anatomical entity [DOID:7] <12>(143|187) (147|103|58)
+ 1:   immune system disease [DOID:2914] <4>(39|47) (42|27|16)
0:   lymphatic system disease [DOID:75] <9>(4|7) (5|3|1)
- 1:   hemophagocytic lymphohistiocytosis [DOID:0050120] <5>(0|0) (0|0|0)
- 1:   histiocytosis [DOID:3405] <5>(0|0) (0|0|0)
- 1:   splenic disease [DOID:2529] <5>(0|0) (0|0|0)
- 1:   lymph node disease [DOID:9942] <2>(4|7) (5|3|1)
- 1:   lymphedema [DOID:4977] <2>(0|0) (0|0|0)
- 1:   thymus gland disease [DOID:533] <2>(0|0) (0|0|0)
- 1:   Hennekam syndrome [DOID:0060366](0|0) (0|0|0)
- 1:   lymphangitis [DOID:9317](0|0) (0|0|0)
- 1:   lymphocele [DOID:4347](0|0) (0|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
Hemopexin-like domain0.0006067Direct
Metalloproteases ("zincins"), catalytic domain0.002088Inherited
PGBD-like0.002836Inherited
MHC antigen-recognition domain0.01006Inherited


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Family

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SCOP termFDR (all)Annotation (direct or inherited)
Matrix metalloproteases, catalytic domain0.0004438Direct
Hemopexin-like domain0.0004438Direct
MMP N-terminal domain0.002126Inherited
S100 proteins0.004187Inherited
MHC antigen-recognition domain0.00813Inherited
C1 set domains (antibody constant domain-like)0.01119Inherited
TNF-like0.1931Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Hemopexin-like domain0.0003726Direct
Metalloproteases ("zincins"), catalytic domain0.001363Inherited
PGBD-like0.001869Inherited
MHC antigen-recognition domain0.007021Inherited
TNF-like0.1778Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
55486,50923
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 50923 - Hemopexin-like domain
  • 0.0007161Direct
    47090,55486
  • 47090 - PGBD-like
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 0.001869Inherited
    54452,48726
  • 54452 - MHC antigen-recognition domain
  • 48726 - Immunoglobulin
  • 0.004985Inherited

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    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    47090,55486,50923
  • 47090 - PGBD-like
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 50923 - Hemopexin-like domain
  • 0.00381Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
    (show help)