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Disease Ontology (DO): arthritis

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Root: DO Hierarchy (disease ontology from University of Maryland)

Shortest distance to current term (+ for parents, - for children) DO term [DO ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + + + 6:   disease [DOID:4] <8>
+ + + + + 5:   disease of anatomical entity [DOID:7] <12>(143|187) (147|103|58)
+ + + + 4:   musculoskeletal system disease [DOID:17] <3>(29|42) (37|17|6)
+ + + 3:   connective tissue disease [DOID:65] <22>(23|31) (28|11|4)
+ + 2:   bone disease [DOID:0080001] <5>(19|22) (24|8|3)
+ 1:   bone inflammation disease [DOID:3342] <8>(15|16) (18|6|1)
0:   arthritis [DOID:848] <7>(10|11) (12|5|1)
- 1:   rheumatoid arthritis [DOID:7148] <1>(2|5) (2|0|0)
- 1:   adult-onset Still's disease [DOID:14256](0|0) (0|0|0)
- 1:   chondrocalcinosis [DOID:1156](0|0) (0|0|0)
- 1:   gout [DOID:13189](1|0) (2|0|0)
- 1:   osteoarthritis [DOID:8398](0|0) (0|0|0)
- 1:   reactive arthritis [DOID:6196](0|0) (0|0|0)
- 1:   septic arthritis [DOID:813](0|0) (0|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
TNF receptor-like0.00000000000006044Direct
Interleukin 8-like chemokines0.000000006371Direct
TNF-like0.000002116Direct
FnI-like domain0.00001555Direct
TSP-1 type 1 repeat0.00005551Direct
TIMP-like0.0004938Direct
Hemopexin-like domain0.0006951Direct
PGBD-like0.0007854Direct
PRTase-like0.0009047Direct
4-helical cytokines0.8915Inherited


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Family

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SCOP termFDR (all)Annotation (direct or inherited)
TNF receptor-like0.0000000000009404Direct
Interleukin 8-like chemokines0.000000006481Direct
TNF-like0.000001906Direct
TSP-1 type 1 repeat0.00005094Direct
Interleukin-1 (IL-1)0.0001792Direct
C2 set domains0.0004295Direct
Hemopexin-like domain0.0005708Direct
MMP N-terminal domain0.0006345Direct
Tissue inhibitor of metalloproteinases, TIMP0.0006604Direct
C-type lectin domain0.003222Inherited
Short-chain cytokines0.794Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
TNF receptor-like0.00000000000002673Direct
Interleukin 8-like chemokines0.00000000299Direct
TNF-like0.000001118Direct
FnI-like domain0.000008645Direct
TSP-1 type 1 repeat0.0000321Direct
TIMP-like0.0003018Direct
Hemopexin-like domain0.0004275Direct
PGBD-like0.0004875Direct
PRTase-like0.000566Direct
Family A G protein-coupled receptor-like0.0008046Direct
MFS general substrate transporter0.313Inherited
4-helical cytokines0.8196Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
57586,57586
  • 57586 - TNF receptor-like
  • 57586 - TNF receptor-like
  • 0.000000000004208Direct
    57184,57603
  • 57184 - Growth factor receptor domain
  • 57603 - FnI-like domain
  • 0.00007188Direct
    57440,57440
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 0.000347Direct
    47090,55486
  • 47090 - PGBD-like
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 0.0004875Direct
    57603,82895
  • 57603 - FnI-like domain
  • 82895 - TSP-1 type 1 repeat
  • 0.000566Direct

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    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    57586,57586,57586
  • 57586 - TNF receptor-like
  • 57586 - TNF receptor-like
  • 57586 - TNF receptor-like
  • 0.00000603Direct


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
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