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Disease Ontology (DO): lung disease

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Root: DO Hierarchy (disease ontology from University of Maryland)

Shortest distance to current term (+ for parents, - for children) DO term [DO ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + 4:   disease [DOID:4] <8>
+ + + 3:   disease of anatomical entity [DOID:7] <12>(143|187) (147|103|58)
+ + 2:   respiratory system disease [DOID:1579] <4>(29|38) (30|14|7)
+ 1:   lower respiratory tract disease [DOID:0050161] <3>(25|33) (26|13|7)
0:   lung disease [DOID:850] <16>(14|18) (15|6|3)
- 1:   pneumonia [DOID:552] <8>(0|1) (2|0|1)
- 1:   interstitial lung disease [DOID:3082] <5>(5|7) (5|2|0)
- 1:   respiratory failure [DOID:11162] <4>(0|0) (0|0|0)
- 1:   obstructive lung disease [DOID:2320] <1>(4|5) (4|1|1)
- 1:   acute chest syndrome [DOID:1584](0|0) (0|0|0)
- 1:   bronchiolitis [DOID:2942](1|0) (1|0|0)
- 1:   lung abscess [DOID:0060317](0|0) (0|0|0)
- 1:   lymphangioleiomyomatosis [DOID:3319](0|0) (0|0|0)
- 1:   meconium aspiration syndrome [DOID:11049](0|0) (0|0|0)
- 1:   middle lobe syndrome [DOID:2810](0|0) (0|0|0)
- 1:   pulmonary alveolar microlithiasis [DOID:12117](0|0) (0|0|0)
- 1:   pulmonary alveolar proteinosis [DOID:12120](0|0) (0|0|0)
- 1:   pulmonary immaturity [DOID:424](0|0) (0|0|0)
- 1:   pulmonary plasma cell granuloma [DOID:3677](0|0) (0|0|0)
- 1:   rheumatoid lung disease [DOID:849](0|0) (0|0|0)
- 1:   silo filler's disease [DOID:4374](0|0) (0|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
Nitric oxide (NO) synthase oxygenase domain0Direct
PGBD-like0.0000003886Direct
Triple coiled coil domain of C-type lectins0.00002173Direct
Hemopexin-like domain0.00004465Direct
Ferredoxin reductase-like, C-terminal NADP-linked domain0.0001468Direct
Riboflavin synthase domain-like0.0001468Direct
Serine protease inhibitors0.0002346Direct
FnI-like domain0.0003324Direct
Insulin-like0.002077Inherited
Cytokine0.005211Inherited
Kringle-like0.1118Inherited
Flavoproteins0.3572Inherited
RNI-like0.5351Inherited
Toll/Interleukin receptor TIR domain1Inherited


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Family

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SCOP termFDR (all)Annotation (direct or inherited)
Nitric oxide (NO) synthase oxygenase domain0Direct
MMP N-terminal domain0.000000407Direct
Matrix metalloproteases, catalytic domain0.000002821Direct
Triple coiled coil domain of C-type lectins0.0000179Direct
Hemopexin-like domain0.00004538Direct
Cytochrome p450 reductase N-terminal domain-like0.0001863Direct
Interleukin-1 (IL-1)0.000503Direct
Platelet-derived growth factor-like0.000503Direct
NADPH-cytochrome p450 reductase FAD-binding domain-like0.0007087Direct
NADPH-cytochrome p450 reductase-like0.0007087Direct
Pentraxin (pentaxin)0.0007087Direct
Sir2 family of transcriptional regulators0.0007087Direct
Insulin-like0.001696Inherited
Globins0.01628Inherited
Growth factor receptor domain0.09404Inherited
Interferons/interleukin-10 (IL-10)0.4994Inherited
Short-chain cytokines0.7752Inherited
Toll/Interleukin receptor TIR domain1Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Nitric oxide (NO) synthase oxygenase domain0Direct
PGBD-like0.0000001979Direct
Triple coiled coil domain of C-type lectins0.00001219Direct
Hemopexin-like domain0.00002563Direct
Riboflavin synthase domain-like0.00008748Direct
Ferredoxin reductase-like, C-terminal NADP-linked domain0.00008748Direct
Serine protease inhibitors0.0001409Direct
FnI-like domain0.0002015Direct
Insulin-like0.001353Inherited
Cytokine0.003536Inherited
Globin-like0.01326Inherited
Kringle-like0.08907Inherited
Flavoproteins0.3066Inherited
RNI-like0.4726Inherited
Toll/Interleukin receptor TIR domain0.9983Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
47090,55486
  • 47090 - PGBD-like
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 0.0000001979Direct
    57944,56436
  • 57944 - Triple coiled coil domain of C-type lectins
  • 56436 - C-type lectin-like
  • 0.00001219Direct
    57440,50494
  • 57440 - Kringle-like
  • 50494 - Trypsin-like serine proteases
  • 0.0000473Direct
    57440,57440
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 0.0000473Direct
    55486,50923
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 50923 - Hemopexin-like domain
  • 0.0002259Direct
    52833,47616
  • 52833 - Thioredoxin-like
  • 47616 - GST C-terminal domain-like
  • 0.2264Inherited

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    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    47090,55486,50923
  • 47090 - PGBD-like
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 50923 - Hemopexin-like domain
  • 0.00008748Direct
    57440,57440,57440
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 0.001353Inherited
    49265,49265,49265
  • 49265 - Fibronectin type III
  • 49265 - Fibronectin type III
  • 49265 - Fibronectin type III
  • 0.0122Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
    (show help)