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Disease Ontology (DO): collagen disease

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Root: DO Hierarchy (disease ontology from University of Maryland)

Shortest distance to current term (+ for parents, - for children) DO term [DO ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + 4:   disease [DOID:4] <8>
+ + + 3:   disease of anatomical entity [DOID:7] <12>(143|187) (147|103|58)
+ + 2:   musculoskeletal system disease [DOID:17] <3>(29|42) (37|17|6)
+ 1:   connective tissue disease [DOID:65] <22>(23|31) (28|11|4)
0:   collagen disease [DOID:854] <5>(7|11) (8|2|1)
- 1:   Ehlers-Danlos syndrome [DOID:13359] <6>(1|1) (1|0|0)
- 1:   scleroderma [DOID:419] <2>(6|10) (7|2|1)
- 1:   disseminated eosinophilic collagen disease [DOID:9499](0|0) (0|0|0)
- 1:   mixed connective tissue disease [DOID:3492](0|0) (0|0|0)
- 1:   polymyalgia rheumatica [DOID:853](0|0) (0|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
SMAD MH1 domain0.0002205Direct
PGBD-like0.004213Inherited
Hemopexin-like domain0.008731Inherited
FnI-like domain0.05242Inherited
Interleukin 8-like chemokines0.1408Inherited
4-helical cytokines0.1667Inherited
TNF-like0.2384Inherited


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Family

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SCOP termFDR (all)Annotation (direct or inherited)
Pentraxin (pentaxin)0.00003041Direct
SMAD domain0.0001565Direct
SMAD MH1 domain0.0001565Direct
Platelet-derived growth factor-like0.0002787Direct
VWC domain0.001011Inherited
Matrix metalloproteases, catalytic domain0.002819Inherited
MMP N-terminal domain0.002819Inherited
Hemopexin-like domain0.006001Inherited
Interleukin-1 (IL-1)0.01384Inherited
Interleukin 8-like chemokines0.114Inherited
TNF-like0.2016Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
SMAD MH1 domain0.0001321Direct
PGBD-like0.002836Inherited
Hemopexin-like domain0.00601Inherited
Snake toxin-like0.01792Inherited
FnI-like domain0.03995Inherited
Interleukin 8-like chemokines0.1138Inherited
4-helical cytokines0.1357Inherited
TNF-like0.1991Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
47090,55486
  • 47090 - PGBD-like
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 0.002836Inherited
    57440,57440
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 0.02919Inherited

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    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    57440,57440,57440
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 0.004344Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
    (show help)