SUPERFAMILY 1.75 HMM library and genome assignments server

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Disease Ontology (DO): chronic myeloid leukemia

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Root: DO Hierarchy (disease ontology from University of Maryland)

Shortest distance to current term (+ for parents, - for children) DO term [DO ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + + + + + 8:   disease [DOID:4] <8>
+ + + + + + + 7:   disease of cellular proliferation [DOID:14566] <3>(123|191) (129|118|56)
+ + + + + + 6:   cancer [DOID:162] <2>(115|181) (120|113|54)
+ + + + + 5:   organ system cancer [DOID:0050686] <14>(66|106) (72|58|31)
+ + + + 4:   immune system cancer [DOID:0060083] <3>(31|42) (33|27|13)
+ + + 3:   hematologic cancer [DOID:2531] <7>(30|42) (32|25|13)
+ + 2:   leukemia [DOID:1240] <11>(14|23) (16|19|11)
+ 1:   myeloid leukemia [DOID:8692] <4>(6|11) (8|11|5)
0:   chronic myeloid leukemia [DOID:8552] <1>(5|6) (5|4|2)
- 1:   familial chronic myelocytic leukemia-like syndrome [DOID:0060761](0|0) (0|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
STAT0.0001901Direct
Transcription factor STAT-4 N-domain0.0001901Direct
SH2 domain0.0002744Direct
MHC antigen-recognition domain0.0006522Direct
SOCS box-like0.000833Direct


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Family

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SCOP termFDR (all)Annotation (direct or inherited)
STAT DNA-binding domain0.0001296Direct
STAT0.0001296Direct
Transcription factor STAT-4 N-domain0.0001296Direct
SH2 domain0.0001561Direct
MHC antigen-recognition domain0.0003831Direct
SOCS box-like0.000573Direct


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
Plot tree as:   Download Newick format tree:
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
STAT0.0001135Direct
Transcription factor STAT-4 N-domain0.0001135Direct
SH2 domain0.0001659Direct
MHC antigen-recognition domain0.0004013Direct
SOCS box-like0.0005188Direct

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
55550,158235
  • 55550 - SH2 domain
  • 158235 - SOCS box-like
  • 0.0001135Direct
    49417,55550
  • 49417 - p53-like transcription factors
  • 55550 - SH2 domain
  • 0.0001135Direct
    48092,47655
  • 48092 - Transcription factor STAT-4 N-domain
  • 47655 - STAT
  • 0.0001135Direct
    47655,49417
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 0.0001135Direct

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    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    47655,49417,55550
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 55550 - SH2 domain
  • 0.0001135Direct
    48092,47655,49417
  • 48092 - Transcription factor STAT-4 N-domain
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 0.0001135Direct


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
    (show help)