SUPERFAMILY 1.75 HMM library and genome assignments server

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Disease Ontology (DO): substance dependence

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Root: DO Hierarchy (disease ontology from University of Maryland)

Shortest distance to current term (+ for parents, - for children) DO term [DO ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + 3:   disease [DOID:4] <8>
+ + 2:   disease of mental health [DOID:150] <12>(23|30) (24|14|4)
+ 1:   substance-related disorder [DOID:303] <3>(6|8) (6|5|1)
0:   substance dependence [DOID:9973] <3>(6|8) (6|5|1)
- 1:   drug dependence [DOID:9974] <4>(3|3) (3|1|0)
- 1:   alcohol dependence [DOID:0050741](0|0) (0|0|0)
- 1:   nicotine dependence [DOID:0050742](0|0) (0|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
p53 tetramerization domain0Direct
Nicotinic receptor ligand binding domain-like0.00000000000005049Direct
Neurotransmitter-gated ion-channel transmembrane pore0.00000000000005049Direct
Voltage-gated potassium channels0.000007842Direct
SNF-like0.00008742Direct
GroES-like0.0004601Direct


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Family

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SCOP termFDR (all)Annotation (direct or inherited)
p53 tetramerization domain0Direct
p53 DNA-binding domain-like0Direct
Nicotinic receptor ligand binding domain-like0.00000000000005221Direct
Neurotransmitter-gated ion-channel transmembrane pore0.00000000000005221Direct
SNF-like0.00006605Direct
Pyridoxal-dependent decarboxylase0.0001293Direct
Alcohol dehydrogenase-like, C-terminal domain0.0002091Direct
Alcohol dehydrogenase-like, N-terminal domain0.0002091Direct


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
p53 tetramerization domain0Direct
Nicotinic receptor ligand binding domain-like0.00000000000002229Direct
Neurotransmitter-gated ion-channel transmembrane pore0.00000000000002229Direct
Voltage-gated potassium channels0.000004286Direct
SNF-like0.00005106Direct
GroES-like0.0002814Direct

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
49417,47719
  • 49417 - p53-like transcription factors
  • 47719 - p53 tetramerization domain
  • 0Direct
    63712,90112
  • 63712 - Nicotinic receptor ligand binding domain-like
  • 90112 - Neurotransmitter-gated ion-channel transmembrane pore
  • 0.00000000000002229Direct
    51735,50129
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 50129 - GroES-like
  • 0.00002089Direct
    57440,57440
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 0.00009699Direct
    50129,51735
  • 50129 - GroES-like
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 0.0001704Direct

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    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    50129,51735,50129
  • 50129 - GroES-like
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 50129 - GroES-like
  • 0.00002089Direct


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
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