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Enzyme Commission (EC): With incorporation of two atoms of oxygen

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Root: EC Hierarchy (from IntEnz release 70)

Shortest distance to current term (+ for parents, - for children) EC term [EC ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + 3:   root [root] <7>
+ + 2:   Oxidoreductases [1] <26>(213|314) (212|187|94)
+ 1:   Acting on single donors with incorporation of molecular oxygen (oxygenases). The oxygen incorporated [1.13] <4>(19|21) (19|5|0)
0:   With incorporation of two atoms of oxygen [1.13.11] <90>(11|18) (11|4|0)
- 1:   (3,5-dihydroxyphenyl)acetyl-CoA 1,2-dioxygenase [1.13.11.80](0|0) (0|0|0)
- 1:   1,2-dihydroxynaphthalene dioxygenase [1.13.11.56](1|0) (1|0|0)
- 1:   1-hydroxy-2-naphthoate 1,2-dioxygenase [1.13.11.38](0|0) (0|0|0)
- 1:   2,3-dihydroxybenzoate 2,3-dioxygenase [1.13.11.28](0|0) (0|0|0)
- 1:   2,3-dihydroxybenzoate 3,4-dioxygenase [1.13.11.14](0|0) (0|0|0)
- 1:   2,3-dihydroxyindole 2,3-dioxygenase [1.13.11.23](0|0) (0|0|0)
- 1:   2,4'-dihydroxyacetophenone dioxygenase [1.13.11.41](0|0) (0|0|0)
- 1:   2,5-dihydroxypyridine 5,6-dioxygenase [1.13.11.9](0|0) (0|0|0)
- 1:   2-amino-1-hydroxyethylphosphonate dioxygenase (glycine-forming) [1.13.11.78](0|0) (0|0|0)
- 1:   2-amino-5-chlorophenol 1,6-dioxygenase [1.13.11.76](0|0) (0|0|0)
- 1:   2-aminophenol 1,6-dioxygenase [1.13.11.74](0|0) (0|0|0)
- 1:   2-hydroxyethylphosphonate dioxygenase [1.13.11.72](0|0) (0|0|0)
- 1:   3,4-dihydroxyphenylacetate 2,3-dioxygenase [1.13.11.15](0|0) (0|0|0)
- 1:   3-carboxyethylcatechol 2,3-dioxygenase [1.13.11.16](1|1) (1|0|0)
- 1:   3-hydroxy-2-methylquinolin-4-one 2,4-dioxygenase [1.13.11.48](0|0) (0|0|0)
- 1:   3-hydroxy-4-oxoquinoline 2,4-dioxygenase [1.13.11.47](0|0) (0|0|0)
- 1:   3-hydroxyanthranilate 3,4-dioxygenase [1.13.11.6](1|1) (1|1|0)
- 1:   4-hydroxy-3-prenylphenylpyruvate oxygenase [1.13.11.83](0|0) (0|0|0)
- 1:   4-hydroxymandelate synthase [1.13.11.46](0|0) (0|0|0)
- 1:   4-hydroxyphenylpyruvate dioxygenase [1.13.11.27](1|1) (1|0|0)
- 1:   5,6-dimethylbenzimidazole synthase [1.13.11.79](1|1) (1|0|0)
- 1:   5-aminosalicylate 1,2-dioxygenase [1.13.11.86](0|0) (0|0|0)
- 1:   5-nitrosalicylate dioxygenase [1.13.11.64](0|0) (0|0|0)
- 1:   7,8-dihydroneopterin oxygenase [1.13.11.81](0|0) (0|0|0)
- 1:   7,8-dihydroxykynurenate 8,8a-dioxygenase [1.13.11.10](0|0) (0|0|0)
- 1:   8'-apo-beta-carotenoid 14',13'-cleaving dioxygenase [1.13.11.67](0|0) (0|0|0)
- 1:   8'-apo-carotenoid 13,14-cleaving dioxygenase [1.13.11.82](0|0) (0|0|0)
- 1:   9-cis-beta-carotene 9',10'-cleaving dioxygenase [1.13.11.68](0|0) (0|0|0)
- 1:   9-cis-epoxycarotenoid dioxygenase [1.13.11.51](0|0) (0|0|0)
- 1:   Acetylacetone-cleaving enzyme [1.13.11.50](0|0) (0|0|0)
- 1:   Acireductone dioxygenase (Fe(2+)-requiring) [1.13.11.54](1|1) (1|1|0)
- 1:   Acireductone dioxygenase (Ni(2+)-requiring) [1.13.11.53](1|1) (1|0|0)
- 1:   All-trans-10'-apo-beta-carotenal 13,14-cleaving dioxygenase [1.13.11.70](0|0) (0|0|0)
- 1:   All-trans-8'-apo-beta-carotenal 15,15'-oxygenase [1.13.11.75](0|0) (0|0|0)
- 1:   Arachidonate 12-lipoxygenase [1.13.11.31](2|2) (2|1|0)
- 1:   Arachidonate 15-lipoxygenase [1.13.11.33](2|2) (2|1|0)
- 1:   Arachidonate 5-lipoxygenase [1.13.11.34](2|1) (2|1|0)
- 1:   Arachidonate 8-lipoxygenase [1.13.11.40](0|0) (0|0|0)
- 1:   Beta-carotene 15,15'-dioxygenase [1.13.11.63](0|0) (0|0|0)
- 1:   Biphenyl-2,3-diol 1,2-dioxygenase [1.13.11.39](1|1) (1|1|0)
- 1:   Caffeate 3,4-dioxygenase [1.13.11.22](0|0) (0|0|0)
- 1:   Carlactone synthase [1.13.11.69](0|0) (0|0|0)
- 1:   Carotenoid isomerooxygenase [1.13.11.65](0|0) (0|0|0)
- 1:   Carotenoid-9',10'-cleaving dioxygenase [1.13.11.71](0|0) (0|0|0)
- 1:   Catechol 1,2-dioxygenase [1.13.11.1](1|1) (1|0|0)
- 1:   Catechol 2,3-dioxygenase [1.13.11.2](1|1) (1|0|0)
- 1:   Chloridazon-catechol dioxygenase [1.13.11.36](0|0) (0|0|0)
- 1:   Chlorite O(2)-lyase [1.13.11.49](0|0) (0|0|0)
- 1:   Crocetin dialdehyde synthase [1.13.11.84](0|0) (0|0|0)
- 1:   Cysteamine dioxygenase [1.13.11.19](0|0) (0|0|0)
- 1:   Cysteine dioxygenase [1.13.11.20](0|1) (0|0|0)
- 1:   Deleted entry [1.13.11.42](0|0) (0|0|0)
- 1:   Deleted entry [1.13.11.13](0|0) (0|0|0)
- 1:   Deleted entry [1.13.11.7](0|0) (0|0|0)
- 1:   Endo-cleaving rubber dioxygenase [1.13.11.87](0|0) (0|0|0)
- 1:   Exo-cleaving rubber dioxygenase [1.13.11.85](0|0) (0|0|0)
- 1:   Gallate dioxygenase [1.13.11.57](0|0) (0|0|0)
- 1:   Gentisate 1,2-dioxygenase [1.13.11.4](0|1) (0|0|0)
- 1:   Homogentisate 1,2-dioxygenase [1.13.11.5](1|1) (1|0|0)
- 1:   Hydroquinone 1,2-dioxygenase [1.13.11.66](0|0) (0|0|0)
- 1:   Hydroxyquinol 1,2-dioxygenase [1.13.11.37](0|0) (0|0|0)
- 1:   Indole 2,3-dioxygenase [1.13.11.17](0|0) (0|0|0)
- 1:   Indoleamine 2,3-dioxygenase [1.13.11.52](1|1) (1|0|0)
- 1:   Isoeugenol monooxygenase [1.13.11.88](0|0) (0|0|0)
- 1:   Lignostilbene alpha-beta-dioxygenase [1.13.11.43](0|0) (0|0|0)
- 1:   Linoleate 10R-lipoxygenase [1.13.11.62](0|0) (0|0|0)
- 1:   Linoleate 11-lipoxygenase [1.13.11.45](1|0) (1|0|0)
- 1:   Linoleate 13S-lipoxygenase [1.13.11.12](2|2) (2|1|0)
- 1:   Linoleate 8R-lipoxygenase [1.13.11.60](2|2) (2|0|0)
- 1:   Linoleate 9S-lipoxygenase [1.13.11.58](2|2) (2|1|0)
- 1:   Linolenate 9R-lipoxygenase [1.13.11.61](0|0) (0|0|0)
- 1:   Methylphosphonate synthase [1.13.11.73](0|0) (0|0|0)
- 1:   Oleate 10S-lipoxygenase [1.13.11.77](0|0) (0|0|0)
- 1:   Peptide-tryptophan 2,3-dioxygenase [1.13.11.26](0|0) (0|0|0)
- 1:   Persulfide dioxygenase [1.13.11.18](1|1) (1|0|0)
- 1:   Protocatechuate 3,4-dioxygenase [1.13.11.3](1|1) (1|0|0)
- 1:   Protocatechuate 4,5-dioxygenase [1.13.11.8](0|0) (0|0|0)
- 1:   Pyrogallol 1,2-oxygenase [1.13.11.35](0|0) (0|0|0)
- 1:   Quercetin 2,3-dioxygenase [1.13.11.24](0|1) (0|0|0)
- 1:   Stizolobate synthase [1.13.11.29](1|1) (1|0|0)
- 1:   Stizolobinate synthase [1.13.11.30](0|0) (0|0|0)
- 1:   Sulfur oxygenase/reductase [1.13.11.55](0|0) (0|0|0)
- 1:   Torulene dioxygenase [1.13.11.59](0|0) (0|0|0)
- 1:   Transferred entry: 1.13.11.60 and 5.4.4.6 [1.13.11.44](0|0) (0|0|0)
- 1:   Transferred entry: 1.13.11.63 [1.13.11.21](0|0) (0|0|0)
- 1:   Transferred entry: 1.13.11.63 [1.13.11.n2](0|0) (0|0|0)
- 1:   Transferred entry: 1.13.11.74 [1.13.11.n1](0|0) (0|0|0)
- 1:   Transferred entry: 1.13.12.16 [1.13.11.32](0|0) (0|0|0)
- 1:   Tryptophan 2,3-dioxygenase [1.13.11.11](1|1) (1|0|0)
- 1:   dioxygenase [1.13.11.25](0|0) (0|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
Aromatic compound dioxygenase0Direct
Lipase/lipooxygenase domain (PLAT/LH2 domain)0Direct
Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase0Direct
Lipoxigenase0Direct
RmlC-like cupins0Direct
Indolic compounds 2,3-dioxygenase-like0Direct
LigB-like0Direct
FMN-dependent nitroreductase-like0.0000006643Direct
Heme-dependent peroxidases0.01212Inherited
Cytochrome P4500.0324Inherited
Metallo-hydrolase/oxidoreductase0.04971Inherited


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Family

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SCOP termFDR (all)Annotation (direct or inherited)
Gentisate 1,2-dioxygenase-like0Direct
Plant lipoxigenases0Direct
Bacterial tryptophan 2,3-dioxygenase0Direct
Indoleamine 2,3-dioxygenase-like0Direct
Aromatic compound dioxygenase0Direct
LigB-like0Direct
Acireductone dioxygenase0Direct
Lipoxigenase N-terminal domain0Direct
Pirin-like0Direct
3-hydroxyanthranilic acid dioxygenase-like0Direct
Animal lipoxigenases0Direct
Extradiol dioxygenases0Direct
Homogentisate dioxygenase0Direct
Cysteine dioxygenase type I0Direct
Myeloperoxidase-like0.00000008649Direct
NADH oxidase/flavin reductase0.0000004914Direct
Glyoxalase II (hydroxyacylglutathione hydrolase)0.002015Inherited
Cytochrome P4500.0313Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Aromatic compound dioxygenase0Direct
LigB-like0Direct
Indolic compounds 2,3-dioxygenase-like0Direct
RmlC-like cupins0Direct
Lipase/lipooxygenase domain (PLAT/LH2 domain)0Direct
Lipoxigenase0Direct
Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase0Direct
FMN-dependent nitroreductase-like0.0000005169Direct
Heme-dependent peroxidases0.0103Inherited
Cytochrome P4500.02784Inherited
Metallo-hydrolase/oxidoreductase0.04294Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
49723,48484
  • 49723 - Lipase/lipooxygenase domain (PLAT/LH2 domain)
  • 48484 - Lipoxigenase
  • 0Direct
    51182,52833
  • 51182 - RmlC-like cupins
  • 52833 - Thioredoxin-like
  • 0Direct
    54593,54593
  • 54593 - Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase
  • 54593 - Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase
  • 0Direct
    51182,51182
  • 51182 - RmlC-like cupins
  • 51182 - RmlC-like cupins
  • 0Direct


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
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