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Enzyme Commission (EC): With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen

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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Root: EC Hierarchy (from IntEnz release 70)

Shortest distance to current term (+ for parents, - for children) EC term [EC ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + 3:   root [root] <7>
+ + 2:   Oxidoreductases [1] <26>(213|314) (212|187|94)
+ 1:   Acting on paired donors, with incorporation or reduction of molecular oxygen. The oxygen incorporate [1.14] <15>(44|52) (44|23|8)
0:   With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [1.14.14] <172>(11|12) (11|4|1)
- 1:   (+)-abscisic acid 8'-hydroxylase [1.14.14.137](0|0) (0|0|0)
- 1:   (+)-menthofuran synthase [1.14.14.143](0|0) (0|0|0)
- 1:   (-)-4'-demethyl-deoxypodophyllotoxin 4-hydroxylase [1.14.14.132](0|0) (0|0|0)
- 1:   (13S,14R)-13-O-acetyl-1-hydroxy-N-methylcanadine 8-hydroxylase [1.14.14.167](0|0) (0|0|0)
- 1:   (E)-2-methylbutanal oxime monooxygenase [1.14.14.41](0|0) (0|0|0)
- 1:   (Methylsulfanyl)alkanaldoxime N-monooxygenase [1.14.14.43](0|0) (0|0|0)
- 1:   (R)-limonene 6-monooxygenase [1.14.14.53](0|0) (0|0|0)
- 1:   (S)-1-hydroxy-N-methylcanadine 13-hydroxylase [1.14.14.163](0|0) (0|0|0)
- 1:   (S)-N-methylcanadine 1-hydroxylase [1.14.14.166](0|0) (0|0|0)
- 1:   (S)-limonene 3-monooxygenase [1.14.14.99](0|0) (0|0|0)
- 1:   (S)-limonene 6-monooxygenase [1.14.14.51](0|0) (0|0|0)
- 1:   (S)-limonene 7-monooxygenase [1.14.14.52](0|0) (0|0|0)
- 1:   1,8-cineole 2-endo-monooxygenase [1.14.14.133](0|0) (0|0|0)
- 1:   1,8-cineole 2-exo-monooxygenase [1.14.14.56](0|0) (0|0|0)
- 1:   11-hydroxysugiol 20-monooxygenase [1.14.14.67](0|0) (0|0|0)
- 1:   11-oxo-beta-amyrin 30-oxidase [1.14.14.115](0|0) (0|0|0)
- 1:   12-hydroxyjasmonoyl-L-amino acid 12-hydroxylase [1.14.14.49](0|0) (0|0|0)
- 1:   17-alpha-hydroxyprogesterone deacetylase [1.14.14.32](0|0) (0|0|0)
- 1:   2,5-diketocamphane 1,2-monooxygenase [1.14.14.108](0|0) (0|0|0)
- 1:   2-hydroxy-1,4-benzoxazin-3-one monooxygenase [1.14.14.110](0|0) (0|0|0)
- 1:   2-hydroxyisoflavanone synthase [1.14.14.87](0|0) (0|0|0)
- 1:   24-hydroxycholesterol 7-alpha-hydroxylase [1.14.14.26](0|0) (0|0|0)
- 1:   25/26-hydroxycholesterol 7-alpha-hydroxylase [1.14.14.29](0|0) (0|0|0)
- 1:   3,6-diketocamphane 1,2-monooxygenase [1.14.14.155](0|0) (0|0|0)
- 1:   3,9-dihydroxypterocarpan 6A-monooxygenase [1.14.14.93](0|0) (0|0|0)
- 1:   3-epi-6-deoxocathasterone 23-monooxygenase [1.14.14.147](0|0) (0|0|0)
- 1:   3-hydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione monooxygenase [1.14.14.12](0|0) (0|0|0)
- 1:   3-hydroxyindolin-2-one monooxygenase [1.14.14.109](0|0) (0|0|0)
- 1:   4'-methoxyisoflavone 2'-hydroxylase [1.14.14.89](0|0) (0|0|0)
- 1:   4-hydroxyphenylacetaldehyde oxime monooxygenase [1.14.14.37](0|0) (0|0|0)
- 1:   4-hydroxyphenylacetate 3-monooxygenase [1.14.14.9](2|2) (2|1|0)
- 1:   5-O-(4-coumaroyl)-D-quinate 3'-monooxygenase [1.14.14.96](0|0) (0|0|0)
- 1:   5-beta-cholestane-3-alpha,7-alpha-diol 12-alpha-hydroxylase [1.14.14.139](0|0) (0|0|0)
- 1:   5-epiaristolochene 1,3-dihydroxylase [1.14.14.149](0|0) (0|0|0)
- 1:   7-deoxyloganate 7-hydroxylase [1.14.14.85](0|0) (0|0|0)
- 1:   8-dimethylallylnaringenin 2'-hydroxylase [1.14.14.142](0|0) (0|0|0)
- 1:   8-epi-inunolide synthase [1.14.14.170](0|0) (0|0|0)
- 1:   9-beta-pimara-7,15-diene oxidase [1.14.14.111](0|0) (0|0|0)
- 1:   Abieta-7,13-dien-18-ol hydroxylase [1.14.14.145](0|0) (0|0|0)
- 1:   Abieta-7,13-diene hydroxylase [1.14.14.144](0|0) (0|0|0)
- 1:   Aflatoxin B synthase [1.14.14.117](0|0) (0|0|0)
- 1:   Albendazole monooxygenase (hydroxylating) [1.14.14.74](0|0) (0|0|0)
- 1:   Albendazole monooxygenase (sufoxide-forming) [1.14.14.73](1|1) (1|1|0)
- 1:   Alkanesulfonate monooxygenase [1.14.14.5](1|1) (1|0|0)
- 1:   Alpha-humulene 10-hydroxylase [1.14.14.113](0|0) (0|0|0)
- 1:   Amorpha-4,11-diene 12 monooxygenase [1.14.14.114](0|0) (0|0|0)
- 1:   Angelicin synthase [1.14.14.148](0|0) (0|0|0)
- 1:   Anthranilate 3-monooxygenase (FAD) [1.14.14.8](0|0) (0|0|0)
- 1:   Aromatase [1.14.14.14](0|0) (0|0|0)
- 1:   Aromatic aldoxime N-monooxygenase [1.14.14.45](0|0) (0|0|0)
- 1:   Averantin hydroxylase [1.14.14.116](0|0) (0|0|0)
- 1:   Bacterial luciferase [1.14.14.3](1|1) (1|0|0)
- 1:   Benzoate 4-monooxygenase [1.14.14.92](0|0) (0|0|0)
- 1:   Beta-amyrin 11-oxidase [1.14.14.152](0|0) (0|0|0)
- 1:   Beta-amyrin 16-alpha-hydroxylase [1.14.14.171](0|0) (0|0|0)
- 1:   Beta-amyrin 16-beta-monooxygenase [1.14.14.63](0|0) (0|0|0)
- 1:   Beta-amyrin 24-hydroxylase [1.14.14.134](0|0) (0|0|0)
- 1:   Beta-amyrin 28-monooxygenase [1.14.14.126](0|0) (0|0|0)
- 1:   Beta-amyrin 6-beta-monooxygenase [1.14.14.64](0|0) (0|0|0)
- 1:   Bursehernin 5'-monooxygenase [1.14.14.131](0|0) (0|0|0)
- 1:   Carnosic acid synthase [1.14.14.61](0|0) (0|0|0)
- 1:   Carotene epsilon-hydroxylase [1.14.14.158](0|0) (0|0|0)
- 1:   Cholesterol 24-hydroxylase [1.14.14.25](0|0) (0|0|0)
- 1:   Cholesterol 7-alpha-monooxygenase [1.14.14.23](0|0) (0|0|0)
- 1:   Costunolide synthase [1.14.14.150](0|0) (0|0|0)
- 1:   Cucurbitadienol 11-hydroxylase [1.14.14.71](0|0) (0|0|0)
- 1:   Dammarenediol 12-hydroxylase [1.14.14.120](0|0) (0|0|0)
- 1:   Deoxysarpagine hydroxylase [1.14.14.136](0|0) (0|0|0)
- 1:   Dibenzothiophene monooxygenase [1.14.14.21](0|0) (0|0|0)
- 1:   Dibenzothiophene sulfone monooxygenase [1.14.14.22](0|0) (0|0|0)
- 1:   Dihydrochelirubine 12-monooxygenase [1.14.14.101](0|0) (0|0|0)
- 1:   Dihydromonacolin L hydroxylase [1.14.14.124](0|0) (0|0|0)
- 1:   Dihydrosanguinarine 10-monooxygenase [1.14.14.100](0|0) (0|0|0)
- 1:   Dimethylnonatriene synthase [1.14.14.59](0|0) (0|0|0)
- 1:   Dimethylsulfone monooxygenase [1.14.14.35](0|0) (0|0|0)
- 1:   Docosahexaenoic acid omega-hydroxylase [1.14.14.79](0|0) (0|0|0)
- 1:   Dolabradiene monooxygenase [1.14.14.159](0|0) (0|0|0)
- 1:   Drimenol monooxygenase [1.14.14.72](0|0) (0|0|0)
- 1:   Ent-cassa-12,15-diene 11-hydroxylase [1.14.14.112](0|0) (0|0|0)
- 1:   Ent-cassadiene hydroxylase [1.14.14.69](0|0) (0|0|0)
- 1:   Ent-isokaurene C2/C3-hydroxylase [1.14.14.76](0|0) (0|0|0)
- 1:   Ent-kaurene monooxygenase [1.14.14.86](0|0) (0|0|0)
- 1:   Ent-kaurenoic acid monooxygenase [1.14.14.107](0|0) (0|0|0)
- 1:   Ent-sandaracopimaradiene 3-hydroxylase [1.14.14.70](0|0) (0|0|0)
- 1:   Ethylenediaminetetraacetate monooxygenase [1.14.14.33](0|0) (0|0|0)
- 1:   Eupatolide synthase [1.14.14.169](0|0) (0|0|0)
- 1:   Farnesoate epoxidase [1.14.14.128](0|0) (0|0|0)
- 1:   Fenbendazole monooxygenase (4'-hydroxylating) [1.14.14.75](0|0) (0|0|0)
- 1:   Ferruginol monooxygenase [1.14.14.60](0|0) (0|0|0)
- 1:   Flavanone 2-hydroxylase [1.14.14.162](0|0) (0|0|0)
- 1:   Flavonoid 3',5'-hydroxylase [1.14.14.81](0|0) (0|0|0)
- 1:   Flavonoid 3'-monooxygenase [1.14.14.82](0|0) (0|0|0)
- 1:   Fraxetin 5-hydroxylase [1.14.14.164](0|0) (0|0|0)
- 1:   Fumitremorgin C monooxygenase [1.14.14.119](0|0) (0|0|0)
- 1:   Geraniol 8-hydroxylase [1.14.14.83](0|0) (0|0|0)
- 1:   Geranylgeraniol 18-hydroxylase [1.14.14.146](0|0) (0|0|0)
- 1:   Germacreene A acid 8-beta-hydroxylase [1.14.14.168](0|0) (0|0|0)
- 1:   Germacrene A hydroxylase [1.14.14.95](0|0) (0|0|0)
- 1:   Glyceollin synthase [1.14.14.135](0|0) (0|0|0)
- 1:   Heme oxygenase (biliverdin-producing) [1.14.14.18](2|2) (2|0|0)
- 1:   Homomethionine N-monooxygenase [1.14.14.42](0|0) (0|0|0)
- 1:   Indole-2-monooxygenase [1.14.14.153](0|0) (0|0|0)
- 1:   Indole-3-carbonyl nitrile 4-hydroxylase [1.14.14.165](0|0) (0|0|0)
- 1:   Indolin-2-one monooxygenase [1.14.14.157](0|0) (0|0|0)
- 1:   Ipsdienol synthase [1.14.14.31](0|0) (0|0|0)
- 1:   Isobutylamine N-monooxygenase [1.14.14.30](0|0) (0|0|0)
- 1:   Isoflavone 2'-hydroxylase [1.14.14.90](0|0) (0|0|0)
- 1:   Isoflavone 3'-hydroxylase [1.14.14.88](0|0) (0|0|0)
- 1:   Isoleucine N-monooxygenase [1.14.14.39](0|0) (0|0|0)
- 1:   Jasmonoyl-L-amino acid 12-hydroxylase [1.14.14.48](0|0) (0|0|0)
- 1:   Laurate 7-monooxygenase [1.14.14.130](0|0) (0|0|0)
- 1:   Leukotriene-B(4) 20-monooxygenase [1.14.14.94](0|0) (0|0|0)
- 1:   Licodione synthase [1.14.14.140](0|0) (0|0|0)
- 1:   Linalool 8-monooxygenase [1.14.14.84](0|0) (0|0|0)
- 1:   Lithocholate 6-beta-hydroxylase [1.14.14.138](0|0) (0|0|0)
- 1:   Long-chain acyl-CoA omega-monooxygenase [1.14.14.129](0|0) (0|0|0)
- 1:   Long-chain alkane monooxygenase [1.14.14.28](0|0) (0|0|0)
- 1:   Long-chain fatty acid omega-monooxygenase [1.14.14.80](0|0) (0|0|0)
- 1:   Marmesin synthase [1.14.14.66](0|0) (0|0|0)
- 1:   Methanesulfonate monooxygenase (FMNH(2)) [1.14.14.34](0|0) (0|0|0)
- 1:   Methyl farnesoate epoxidase [1.14.14.127](0|0) (0|0|0)
- 1:   Methyltetrahydroprotoberberine 14-monooxygenase [1.14.14.97](0|0) (0|0|0)
- 1:   Monacolin L hydroxylase [1.14.14.125](0|0) (0|0|0)
- 1:   N-methylcoclaurine 3'-monooxygenase [1.14.14.102](0|0) (0|0|0)
- 1:   Nepetalactol monooxygenase [1.14.14.161](0|0) (0|0|0)
- 1:   Nitric-oxide synthase (flavodoxin) [1.14.14.47](1|1) (1|0|0)
- 1:   Nitrilotriacetate monooxygenase [1.14.14.10](0|0) (0|0|0)
- 1:   Oryzalexin D synthase [1.14.14.123](0|0) (0|0|0)
- 1:   Oryzalexin E synthase [1.14.14.122](0|0) (0|0|0)
- 1:   Phenol 2-monooxygenase (FADH(2)) [1.14.14.20](0|0) (0|0|0)
- 1:   Phenylacetaldehyde oxime monooxygenase [1.14.14.44](0|0) (0|0|0)
- 1:   Phenylacetate 2-hydroxylase [1.14.14.54](0|0) (0|0|0)
- 1:   Phenylacetonitrile alpha-monooxygenase [1.14.14.77](0|0) (0|0|0)
- 1:   Phenylalanine N-monooxygenase [1.14.14.40](0|0) (0|0|0)
- 1:   Phylloquinone omega-hydroxylase [1.14.14.78](0|0) (0|0|0)
- 1:   Pimeloyl-[acyl-carrier protein] synthase [1.14.14.46](0|0) (0|0|0)
- 1:   Premnaspirodiene oxygenase [1.14.14.151](0|0) (0|0|0)
- 1:   Protopanaxadiol 6-hydroxylase [1.14.14.121](0|0) (0|0|0)
- 1:   Protopine 6-monooxygenase [1.14.14.98](0|0) (0|0|0)
- 1:   Psoralen synthase [1.14.14.141](0|0) (0|0|0)
- 1:   Quinine 3-monooxygenase [1.14.14.55](0|0) (0|0|0)
- 1:   Resorcinol 4-hydroxylase (FADH(2)) [1.14.14.27](0|0) (0|0|0)
- 1:   Salviol synthase [1.14.14.62](0|0) (0|0|0)
- 1:   Squalene monooxygenase [1.14.14.17](1|0) (1|0|0)
- 1:   Steroid 17-alpha-monooxygenase [1.14.14.19](0|0) (0|0|0)
- 1:   Steroid 21-monooxygenase [1.14.14.16](0|0) (0|0|0)
- 1:   Sterol 14-alpha-demethylase [1.14.14.154](0|0) (0|0|0)
- 1:   Styrene monooxygenase [1.14.14.11](0|0) (0|0|0)
- 1:   Sugiol synthase [1.14.14.65](0|0) (0|0|0)
- 1:   Syn-pimaradiene 3-monooxygenase [1.14.14.68](0|0) (0|0|0)
- 1:   Tabersonine 16-hydroxylase [1.14.14.103](0|0) (0|0|0)
- 1:   Tabersonine 3-oxygenase [1.14.14.50](0|0) (0|0|0)
- 1:   Taurochenodeoxycholate 6-alpha-hydroxylase [1.14.14.57](0|0) (0|0|0)
- 1:   Taxane 10-beta-hydroxylase [1.14.14.105](0|0) (0|0|0)
- 1:   Taxane 13-alpha-hydroxylase [1.14.14.106](0|0) (0|0|0)
- 1:   Trans-cinnamate 4-monooxygenase [1.14.14.91](0|0) (0|0|0)
- 1:   Transferred entry: 1.14.13.111 [1.14.14.6](0|0) (0|0|0)
- 1:   Transferred entry: 1.14.14.1 [1.14.14.2](0|0) (0|0|0)
- 1:   Transferred entry: 1.14.15.7 [1.14.14.4](0|0) (0|0|0)
- 1:   Transferred entry: 1.14.19.9 [1.14.14.7](0|0) (0|0|0)
- 1:   Transferred entry: 1.14.99.46 [1.14.14.n1](0|0) (0|0|0)
- 1:   Trimethyltridecatetraene synthase [1.14.14.58](0|0) (0|0|0)
- 1:   Tryprostatin B 6-hydroxylase [1.14.14.118](0|0) (0|0|0)
- 1:   Tryptophan N-monooxygenase [1.14.14.156](0|0) (0|0|0)
- 1:   Tyrosine N-monooxygenase [1.14.14.36](0|0) (0|0|0)
- 1:   Unspecific monooxygenase [1.14.14.1](4|4) (4|2|1)
- 1:   Valine N-monooxygenase [1.14.14.38](0|0) (0|0|0)
- 1:   Vinorine hydroxylase [1.14.14.104](0|0) (0|0|0)
- 1:   Vitamin D 25-hydroxylase [1.14.14.24](0|0) (0|0|0)
- 1:   Zealexin A1 synthase [1.14.14.160](0|0) (0|0|0)
- 1:   monooxygenase [1.14.14.13](0|0) (0|0|0)
- 1:   protein SgcC2] monooxygenase [1.14.14.15](0|0) (0|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
Cytochrome P4500Direct
Heme oxygenase-like0.0000000000002518Direct
Bacterial luciferase-like0.000000000004453Direct
Acyl-CoA dehydrogenase C-terminal domain-like0.00004043Direct
Acyl-CoA dehydrogenase NM domain-like0.0001863Direct
Dimeric alpha+beta barrel0.01481Inherited
Ferredoxin reductase-like, C-terminal NADP-linked domain1Inherited
Flavoproteins1Inherited
Riboflavin synthase domain-like1Inherited
FAD/NAD(P)-binding domain1Inherited
Nitric oxide (NO) synthase oxygenase domain1Inherited


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Family

(show details)
SCOP termFDR (all)Annotation (direct or inherited)
Cytochrome P4500Direct
Bacterial luciferase (alkanal monooxygenase)0Direct
Eukaryotic type heme oxygenase0Direct
Flavodoxin-related0.0000000000001729Direct
Ssud-like monoxygenases0.00000000004502Direct
Medium chain acyl-CoA dehydrogenase, NM (N-terminal and middle) domains0.002188Inherited
Medium chain acyl-CoA dehydrogenase-like, C-terminal domain0.008665Inherited
PG130-like0.08141Inherited
Nitric oxide (NO) synthase oxygenase domain1Inherited
NADPH-cytochrome p450 reductase-like1Inherited
NADPH-cytochrome p450 reductase FAD-binding domain-like1Inherited
FAD/NAD-linked reductases, N-terminal and central domains1Inherited


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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

(show details)
Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Cytochrome P4500Direct
Heme oxygenase-like0.0000000000001796Direct
Bacterial luciferase-like0.000000000003214Direct
Acyl-CoA dehydrogenase C-terminal domain-like0.00003237Direct
Acyl-CoA dehydrogenase NM domain-like0.0001513Direct
Dimeric alpha+beta barrel0.01261Inherited
FAD/NAD(P)-binding domain1Inherited
Flavoproteins1Inherited
Riboflavin synthase domain-like1Inherited
Nitric oxide (NO) synthase oxygenase domain1Inherited
Ferredoxin reductase-like, C-terminal NADP-linked domain1Inherited

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
48264,52218
  • 48264 - Cytochrome P450
  • 52218 - Flavoproteins
  • 0Direct
    56645,47203
  • 56645 - Acyl-CoA dehydrogenase NM domain-like
  • 47203 - Acyl-CoA dehydrogenase C-terminal domain-like
  • 0.00003237Direct
    52218,63380
  • 52218 - Flavoproteins
  • 63380 - Riboflavin synthase domain-like
  • 0.1198Inherited
    51905,51905
  • 51905 - FAD/NAD(P)-binding domain
  • 51905 - FAD/NAD(P)-binding domain
  • 1Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    48264,52218,63380
  • 48264 - Cytochrome P450
  • 52218 - Flavoproteins
  • 63380 - Riboflavin synthase domain-like
  • 0Direct


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