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Enzyme Commission (EC): Acting on CH or CH(2) groups

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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Root: EC Hierarchy (from IntEnz release 70)

Shortest distance to current term (+ for parents, - for children) EC term [EC ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + 2:   root [root] <7>
+ 1:   Oxidoreductases [1] <26>(213|314) (212|187|94)
0:   Acting on CH or CH(2) groups [1.17] <10>(30|24) (29|23|8)
- 1:   With NAD(+) or NADP(+) as acceptor [1.17.1] <11>(13|12) (13|10|6)
- 1:   With other acceptors [1.17.99] <7>(5|2) (5|3|1)
- 1:   With a disulfide as acceptor [1.17.4] <5>(7|5) (6|4|0)
- 1:   With an iron-sulfur protein as acceptor [1.17.7] <4>(6|5) (6|6|1)
- 1:   With oxygen as acceptor [1.17.3] <4>(6|6) (6|5|4)
- 1:   With a cytochrome as acceptor [1.17.2] <3>(0|0) (0|0|0)
- 1:   With a quinone or similar compound as acceptor [1.17.5] <3>(0|0) (0|0|0)
- 1:   With other, known, acceptors [1.17.98] <3>(0|0) (0|0|0)
- 1:   With a copper protein as acceptor [1.17.9] <1>(0|0) (0|0|0)
- 1:   With a flavin as acceptor [1.17.8] <1>(1|0) (1|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
R1 subunit of ribonucleotide reductase, N-terminal domain0Direct
Nitrite and sulphite reductase 4Fe-4S domain-like0Direct
Molybdenum cofactor-binding domain0Direct
PFL-like glycyl radical enzymes0Direct
Dihydropteroate synthetase-like0Direct
YebC-like0Direct
Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain0Direct
Ferritin-like0Direct
CO dehydrogenase molybdoprotein N-domain-like5.098e-16Direct
CO dehydrogenase flavoprotein C-terminal domain-like0.000000000000001014Direct
Enolase C-terminal domain-like0.000000000000001014Direct
CO dehydrogenase ISP C-domain like0.00000000000003283Direct
2Fe-2S ferredoxin-like0.0000000003204Direct
NAD(P)-binding Rossmann-fold domains0.0000000004811Direct
alpha-helical ferredoxin0.0000001693Direct
Hedgehog/intein (Hint) domain0.00005934Direct
SCOP hierarchy in SUPERFAMILY0.0001306Direct
Homing endonucleases0.0001681Direct
4Fe-4S ferredoxins0.0003154Direct
ADC-like0.001578Inherited
Inosine monophosphate dehydrogenase (IMPDH)0.001696Inherited
Formate dehydrogenase/DMSO reductase, domains 1-30.004467Inherited
ARM repeat0.005998Inherited
Formate/glycerate dehydrogenase catalytic domain-like0.4404Inherited
FAD-binding/transporter-associated domain-like0.7753Inherited
Acyl-CoA dehydrogenase NM domain-like0.8394Inherited
Acyl-CoA dehydrogenase C-terminal domain-like0.8394Inherited
FMN-linked oxidoreductases1Inherited
Nucleic acid-binding proteins1Inherited
FAD/NAD(P)-binding domain1Inherited


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Family

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SCOP termFDR (all)Annotation (direct or inherited)
Ribonucleotide reductase-like0Direct
Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain0Direct
YebC-like0Direct
Nitrite and sulphite reductase 4Fe-4S domain-like0Direct
R1 subunit of ribonucleotide reductase, N-terminal domain0Direct
R1 subunit of ribonucleotide reductase, C-terminal domain0Direct
Molybdenum cofactor-binding domain0Direct
B12-dependent (class II) ribonucleotide reductase0Direct
Dihydrodipicolinate reductase-like0Direct
CO dehydrogenase molybdoprotein N-domain-like3.695e-16Direct
CO dehydrogenase flavoprotein C-terminal domain-like0.000000000000005618Direct
CO dehydrogenase flavoprotein N-terminal domain-like0.0000000000000137Direct
CO dehydrogenase ISP C-domain like0.00000000000002121Direct
Dihydropteroate synthetase0.00000000003516Direct
2Fe-2S ferredoxin domains from multidomain proteins0.000000007566Direct
Formate dehydrogenase/DMSO reductase, C-terminal domain0.001185Inherited
Formate dehydrogenase/DMSO reductase, domains 1-30.00417Inherited
D-glucarate dehydratase-like0.03152Inherited
acyl-CoA oxidase N-terminal domains0.03326Inherited
acyl-CoA oxidase C-terminal domains0.03672Inherited
Formate/glycerate dehydrogenases, substrate-binding domain0.2328Inherited
Inosine monophosphate dehydrogenase (IMPDH)0.2499Inherited
Formate/glycerate dehydrogenases, NAD-domain0.5409Inherited
Cold shock DNA-binding domain-like0.7352Inherited


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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
YebC-like0Direct
Ferritin-like0Direct
Molybdenum cofactor-binding domain0Direct
PFL-like glycyl radical enzymes0Direct
Dihydropteroate synthetase-like0Direct
Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain0Direct
R1 subunit of ribonucleotide reductase, N-terminal domain0Direct
Nitrite and sulphite reductase 4Fe-4S domain-like0Direct
CO dehydrogenase molybdoprotein N-domain-like3.545e-16Direct
Enolase C-terminal domain-like7.066e-16Direct
CO dehydrogenase flavoprotein C-terminal domain-like7.066e-16Direct
CO dehydrogenase ISP C-domain like0.00000000000002322Direct
2Fe-2S ferredoxin-like0.000000000237Direct
NAD(P)-binding Rossmann-fold domains0.0000000003571Direct
alpha-helical ferredoxin0.0000001301Direct
Hedgehog/intein (Hint) domain0.00004765Direct
Homing endonucleases0.0001365Direct
4Fe-4S ferredoxins0.0002573Direct
ADC-like0.001309Inherited
Inosine monophosphate dehydrogenase (IMPDH)0.001409Inherited
Formate dehydrogenase/DMSO reductase, domains 1-30.003747Inherited
ARM repeat0.005053Inherited
Formate/glycerate dehydrogenase catalytic domain-like0.4008Inherited
FAD-binding/transporter-associated domain-like0.714Inherited
Acyl-CoA dehydrogenase NM domain-like0.7741Inherited
Acyl-CoA dehydrogenase C-terminal domain-like0.7741Inherited
Nucleic acid-binding proteins1Inherited
FAD/NAD(P)-binding domain1Inherited
FMN-linked oxidoreductases1Inherited

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
54862,48371
  • 54862 - 4Fe-4S ferredoxins
  • 48371 - ARM repeat
  • 0Direct
    51604,56014
  • 51604 - Enolase C-terminal domain-like
  • 56014 - Nitrite and sulphite reductase 4Fe-4S domain-like
  • 0Direct
    47240,-9
  • 47240 - Ferritin-like
  • -9 - PDB
  • 0Direct
    55608,51998
  • 55608 - Homing endonucleases
  • 51998 - PFL-like glycyl radical enzymes
  • 0Direct
    51717,56014
  • 51717 - Dihydropteroate synthetase-like
  • 56014 - Nitrite and sulphite reductase 4Fe-4S domain-like
  • 0Direct
    75625,51998
  • 75625 - YebC-like
  • 51998 - PFL-like glycyl radical enzymes
  • 0Direct
    51395,56014
  • 51395 - FMN-linked oxidoreductases
  • 56014 - Nitrite and sulphite reductase 4Fe-4S domain-like
  • 0Direct
    51735,55347
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 55347 - Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain
  • 0Direct
    51366,56014
  • 51366 - Ribulose-phoshate binding barrel
  • 56014 - Nitrite and sulphite reductase 4Fe-4S domain-like
  • 0Direct
    48168,51998
  • 48168 - R1 subunit of ribonucleotide reductase, N-terminal domain
  • 51998 - PFL-like glycyl radical enzymes
  • 0Direct
    51412,56014
  • 51412 - Inosine monophosphate dehydrogenase (IMPDH)
  • 56014 - Nitrite and sulphite reductase 4Fe-4S domain-like
  • 0Direct
    54665,56003
  • 54665 - CO dehydrogenase molybdoprotein N-domain-like
  • 56003 - Molybdenum cofactor-binding domain
  • 3.545e-16Direct
    56176,55447
  • 56176 - FAD-binding/transporter-associated domain-like
  • 55447 - CO dehydrogenase flavoprotein C-terminal domain-like
  • 7.066e-16Direct
    54292,47741
  • 54292 - 2Fe-2S ferredoxin-like
  • 47741 - CO dehydrogenase ISP C-domain like
  • 0.00000000000002322Direct
    47741,56176
  • 47741 - CO dehydrogenase ISP C-domain like
  • 56176 - FAD-binding/transporter-associated domain-like
  • 0.000000000002586Direct
    55447,54665
  • 55447 - CO dehydrogenase flavoprotein C-terminal domain-like
  • 54665 - CO dehydrogenase molybdoprotein N-domain-like
  • 0.000000001022Direct
    54862,53706
  • 54862 - 4Fe-4S ferredoxins
  • 53706 - Formate dehydrogenase/DMSO reductase, domains 1-3
  • 0.000001057Direct
    54292,54862
  • 54292 - 2Fe-2S ferredoxin-like
  • 54862 - 4Fe-4S ferredoxins
  • 0.000002214Direct
    53706,50692
  • 53706 - Formate dehydrogenase/DMSO reductase, domains 1-3
  • 50692 - ADC-like
  • 0.0008625Direct
    50249,50249
  • 50249 - Nucleic acid-binding proteins
  • 50249 - Nucleic acid-binding proteins
  • 0.002322Inherited
    47203,47203
  • 47203 - Acyl-CoA dehydrogenase C-terminal domain-like
  • 47203 - Acyl-CoA dehydrogenase C-terminal domain-like
  • 0.03431Inherited
    52283,51735
  • 52283 - Formate/glycerate dehydrogenase catalytic domain-like
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 0.3745Inherited
    56645,47203
  • 56645 - Acyl-CoA dehydrogenase NM domain-like
  • 47203 - Acyl-CoA dehydrogenase C-terminal domain-like
  • 0.7677Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    54862,53706,50692
  • 54862 - 4Fe-4S ferredoxins
  • 53706 - Formate dehydrogenase/DMSO reductase, domains 1-3
  • 50692 - ADC-like
  • 0Direct
    47741,56176,55447
  • 47741 - CO dehydrogenase ISP C-domain like
  • 56176 - FAD-binding/transporter-associated domain-like
  • 55447 - CO dehydrogenase flavoprotein C-terminal domain-like
  • 0.000000000001638Direct
    54292,47741,56176
  • 54292 - 2Fe-2S ferredoxin-like
  • 47741 - CO dehydrogenase ISP C-domain like
  • 56176 - FAD-binding/transporter-associated domain-like
  • 0.000000000002586Direct
    55447,54665,56003
  • 55447 - CO dehydrogenase flavoprotein C-terminal domain-like
  • 54665 - CO dehydrogenase molybdoprotein N-domain-like
  • 56003 - Molybdenum cofactor-binding domain
  • 0.000000001022Direct
    56176,55447,54665
  • 56176 - FAD-binding/transporter-associated domain-like
  • 55447 - CO dehydrogenase flavoprotein C-terminal domain-like
  • 54665 - CO dehydrogenase molybdoprotein N-domain-like
  • 0.000000001022Direct
    50249,50249,50249
  • 50249 - Nucleic acid-binding proteins
  • 50249 - Nucleic acid-binding proteins
  • 50249 - Nucleic acid-binding proteins
  • 0.000000001832Direct
    54292,54862,53706
  • 54292 - 2Fe-2S ferredoxin-like
  • 54862 - 4Fe-4S ferredoxins
  • 53706 - Formate dehydrogenase/DMSO reductase, domains 1-3
  • 0.000001057Direct
    56645,47203,47203
  • 56645 - Acyl-CoA dehydrogenase NM domain-like
  • 47203 - Acyl-CoA dehydrogenase C-terminal domain-like
  • 47203 - Acyl-CoA dehydrogenase C-terminal domain-like
  • 0.03431Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
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