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Enzyme Commission (EC): With NAD(+) or NADP(+) as acceptor

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Root: EC Hierarchy (from IntEnz release 70)

Shortest distance to current term (+ for parents, - for children) EC term [EC ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + 3:   root [root] <7>
+ + 2:   Oxidoreductases [1] <26>(213|314) (212|187|94)
+ 1:   Acting on CH or CH(2) groups [1.17] <10>(30|24) (29|23|8)
0:   With NAD(+) or NADP(+) as acceptor [1.17.1] <11>(13|12) (13|10|6)
- 1:   4-hydroxy-tetrahydrodipicolinate reductase [1.17.1.8](2|2) (2|1|0)
- 1:   CDP-4-dehydro-6-deoxyglucose reductase [1.17.1.1](0|0) (0|0|0)
- 1:   Formate dehydrogenase [1.17.1.9](6|4) (6|4|2)
- 1:   Formate dehydrogenase (NAD(+), ferredoxin) [1.17.1.11](0|0) (0|0|0)
- 1:   Formate dehydrogenase (NADP(+)) [1.17.1.10](0|0) (0|0|0)
- 1:   Leucoanthocyanidin reductase [1.17.1.3](0|0) (0|0|0)
- 1:   Nicotinate dehydrogenase [1.17.1.5](0|0) (0|0|0)
- 1:   Transferred entry: 1.1.1.395 [1.17.1.6](0|0) (0|0|0)
- 1:   Transferred entry: 1.17.7.4 [1.17.1.2](0|0) (0|0|0)
- 1:   Transferred entry: 1.2.1.91 [1.17.1.7](0|0) (0|0|0)
- 1:   Xanthine dehydrogenase [1.17.1.4](6|6) (6|5|4)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain0Direct
NAD(P)-binding Rossmann-fold domains0Direct
Formate/glycerate dehydrogenase catalytic domain-like0.0000000009369Direct
2Fe-2S ferredoxin-like0.0000001003Direct
CO dehydrogenase flavoprotein C-terminal domain-like0.0000004887Direct
Molybdenum cofactor-binding domain0.00000283Direct
CO dehydrogenase molybdoprotein N-domain-like0.000005511Direct
FAD-binding/transporter-associated domain-like0.000005511Direct
CO dehydrogenase ISP C-domain like0.00002052Direct
ADC-like0.0002771Direct
Formate dehydrogenase/DMSO reductase, domains 1-30.0002771Direct
4Fe-4S ferredoxins0.9604Inherited
alpha-helical ferredoxin1Inherited


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Family

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SCOP termFDR (all)Annotation (direct or inherited)
Dihydrodipicolinate reductase-like0Direct
Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain0Direct
Formate/glycerate dehydrogenases, substrate-binding domain0.0000000000001179Direct
Formate/glycerate dehydrogenases, NAD-domain0.000000002879Direct
CO dehydrogenase flavoprotein C-terminal domain-like0.000002242Direct
CO dehydrogenase flavoprotein N-terminal domain-like0.000002242Direct
Molybdenum cofactor-binding domain0.000006818Direct
CO dehydrogenase molybdoprotein N-domain-like0.00001259Direct
2Fe-2S ferredoxin domains from multidomain proteins0.00001259Direct
CO dehydrogenase ISP C-domain like0.00004272Direct
Formate dehydrogenase/DMSO reductase, C-terminal domain0.0004787Direct
Formate dehydrogenase/DMSO reductase, domains 1-30.0004787Direct


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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain0Direct
NAD(P)-binding Rossmann-fold domains0Direct
Formate/glycerate dehydrogenase catalytic domain-like0.0000000006984Direct
2Fe-2S ferredoxin-like0.00000007677Direct
CO dehydrogenase flavoprotein C-terminal domain-like0.0000003789Direct
Molybdenum cofactor-binding domain0.000002222Direct
CO dehydrogenase molybdoprotein N-domain-like0.00000434Direct
FAD-binding/transporter-associated domain-like0.00000434Direct
CO dehydrogenase ISP C-domain like0.00001635Direct
Formate dehydrogenase/DMSO reductase, domains 1-30.0002259Direct
ADC-like0.0002259Direct
4Fe-4S ferredoxins0.8887Inherited
alpha-helical ferredoxin1Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
47741,56176
  • 47741 - CO dehydrogenase ISP C-domain like
  • 56176 - FAD-binding/transporter-associated domain-like
  • 0Direct
    55447,54665
  • 55447 - CO dehydrogenase flavoprotein C-terminal domain-like
  • 54665 - CO dehydrogenase molybdoprotein N-domain-like
  • 0Direct
    54862,53706
  • 54862 - 4Fe-4S ferredoxins
  • 53706 - Formate dehydrogenase/DMSO reductase, domains 1-3
  • 0Direct
    54292,54862
  • 54292 - 2Fe-2S ferredoxin-like
  • 54862 - 4Fe-4S ferredoxins
  • 0Direct
    51735,55347
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 55347 - Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain
  • 0Direct
    52283,51735
  • 52283 - Formate/glycerate dehydrogenase catalytic domain-like
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 0.0000000005983Direct
    56176,55447
  • 56176 - FAD-binding/transporter-associated domain-like
  • 55447 - CO dehydrogenase flavoprotein C-terminal domain-like
  • 0.0000003789Direct
    54665,56003
  • 54665 - CO dehydrogenase molybdoprotein N-domain-like
  • 56003 - Molybdenum cofactor-binding domain
  • 0.00000434Direct
    54292,47741
  • 54292 - 2Fe-2S ferredoxin-like
  • 47741 - CO dehydrogenase ISP C-domain like
  • 0.00001635Direct
    53706,50692
  • 53706 - Formate dehydrogenase/DMSO reductase, domains 1-3
  • 50692 - ADC-like
  • 0.0002259Direct

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    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    54292,47741,56176
  • 54292 - 2Fe-2S ferredoxin-like
  • 47741 - CO dehydrogenase ISP C-domain like
  • 56176 - FAD-binding/transporter-associated domain-like
  • 0Direct
    54292,54862,53706
  • 54292 - 2Fe-2S ferredoxin-like
  • 54862 - 4Fe-4S ferredoxins
  • 53706 - Formate dehydrogenase/DMSO reductase, domains 1-3
  • 0Direct
    55447,54665,56003
  • 55447 - CO dehydrogenase flavoprotein C-terminal domain-like
  • 54665 - CO dehydrogenase molybdoprotein N-domain-like
  • 56003 - Molybdenum cofactor-binding domain
  • 0Direct
    54862,53706,50692
  • 54862 - 4Fe-4S ferredoxins
  • 53706 - Formate dehydrogenase/DMSO reductase, domains 1-3
  • 50692 - ADC-like
  • 0Direct
    56176,55447,54665
  • 56176 - FAD-binding/transporter-associated domain-like
  • 55447 - CO dehydrogenase flavoprotein C-terminal domain-like
  • 54665 - CO dehydrogenase molybdoprotein N-domain-like
  • 0Direct
    47741,56176,55447
  • 47741 - CO dehydrogenase ISP C-domain like
  • 56176 - FAD-binding/transporter-associated domain-like
  • 55447 - CO dehydrogenase flavoprotein C-terminal domain-like
  • 0Direct


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
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