SUPERFAMILY 1.75 HMM library and genome assignments server

Superfamily is undergoing a server migration - you are now browsing on the new server. Please contact us if you experience any problems.

Enzyme Commission (EC): Acting on the CH-CH group of donors

(show info)

Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Root: EC Hierarchy (from IntEnz release 70)

Shortest distance to current term (+ for parents, - for children) EC term [EC ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + 2:   root [root] <7>
+ 1:   Oxidoreductases [1] <26>(213|314) (212|187|94)
0:   Acting on the CH-CH group of donors [1.3] <9>(40|44) (40|25|12)
- 1:   With NAD(+) or NADP(+) as acceptor [1.3.1] <122>(28|28) (28|20|10)
- 1:   With other acceptors [1.3.99] <43>(3|3) (3|1|0)
- 1:   With an iron-sulfur protein as acceptor [1.3.7] <15>(3|2) (3|0|0)
- 1:   With oxygen as acceptor [1.3.3] <15>(6|6) (6|3|1)
- 1:   With a flavin as acceptor [1.3.8] <14>(2|2) (2|1|0)
- 1:   With a quinone or related compound as acceptor [1.3.5] <6>(7|7) (7|3|1)
- 1:   With other, known, acceptors [1.3.98] <4>(2|2) (2|0|0)
- 1:   With a cytochrome as acceptor [1.3.2] <3>(0|0) (0|0|0)
- 1:   With a disulfide as acceptor [1.3.4] <1>(0|0) (0|0|0)


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Superfamily

(show details)
SCOP termFDR (all)Annotation (direct or inherited)
Coproporphyrinogen III oxidase0Direct
alpha-helical ferredoxin0Direct
Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain0Direct
Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain0Direct
Tetrapyrrole methylase0Direct
Uridine diphospho-N-Acetylenolpyruvylglucosamine reductase, MurB, C-terminal domain0Direct
Acyl-CoA dehydrogenase NM domain-like0Direct
Siroheme synthase middle domains-like0Direct
Acyl-CoA dehydrogenase C-terminal domain-like0Direct
Heme oxygenase-like0Direct
FMN-linked oxidoreductases0Direct
"Helical backbone" metal receptor0Direct
FAD-binding/transporter-associated domain-like0Direct
2Fe-2S ferredoxin-like0.00000000000001823Direct
FabD/lysophospholipase-like0.0000002681Direct
Chorismate mutase II0.00008267Direct
Tudor/PWWP/MBT0.0001602Direct
Probable ACP-binding domain of malonyl-CoA ACP transacylase0.000228Direct
Nucleotide-binding domain0.0004163Direct
ACP-like0.00469Inherited
Ubiquitin-like0.00563Inherited
GroES-like0.02649Inherited
FAD/NAD(P)-binding domain0.02703Inherited
ACT-like0.1679Inherited
Thioesterase/thiol ester dehydrase-isomerase0.4289Inherited
Multiheme cytochromes0.751Inherited
alpha/beta-Hydrolases1Inherited
P-loop containing nucleoside triphosphate hydrolases1Inherited
FAD-linked reductases, C-terminal domain1Inherited
S-adenosyl-L-methionine-dependent methyltransferases1Inherited
Thiolase-like1Inherited
Flavoproteins1Inherited
Radical SAM enzymes1Inherited
NAD(P)-binding Rossmann-fold domains1Inherited
Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain1Inherited
4Fe-4S ferredoxins1Inherited
Dehydroquinate synthase-like1Inherited
NAD(P)-linked oxidoreductase1Inherited
6-phosphogluconate dehydrogenase C-terminal domain-like1Inherited
Inosine monophosphate dehydrogenase (IMPDH)1Inherited


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Family

(show details)
SCOP termFDR (all)Annotation (direct or inherited)
Medium chain acyl-CoA dehydrogenase, NM (N-terminal and middle) domains0Direct
acyl-CoA oxidase C-terminal domains0Direct
Uridine diphospho-N-Acetylenolpyruvylglucosamine reductase (MurB), N-terminal domain0Direct
Siroheme synthase middle domains-like0Direct
Oxygen-independent coproporphyrinogen III oxidase HemN0Direct
Tetrapyrrole methylase0Direct
Nitrogenase iron-molybdenum protein0Direct
FMN-linked oxidoreductases0Direct
Succinate dehydrogenase/fumarate reductase flavoprotein N-terminal domain0Direct
TyrA dimerization domain-like0Direct
Fumarate reductase/Succinate dehydogenase iron-sulfur protein, C-terminal domain0Direct
acyl-CoA oxidase N-terminal domains0Direct
Nitrogenase iron protein-like0Direct
Biliverdin reductase0Direct
PqqC-like0Direct
Coproporphyrinogen III oxidase0Direct
Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain0Direct
Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain0Direct
Siroheme synthase N-terminal domain-like0Direct
Uridine diphospho-N-Acetylenolpyruvylglucosamine reductase, MurB, C-terminal domain0Direct
2Fe-2S ferredoxin domains from multidomain proteins0Direct
Medium chain acyl-CoA dehydrogenase-like, C-terminal domain0Direct
Dihydropyrimidine dehydrogenase, N-terminal domain0.000000000009309Direct
Acyl-carrier protein (ACP)0.00000000003455Direct
FabD-like0.0000000002614Direct
Thioesterase domain of polypeptide, polyketide and fatty acid synthases0.00000002122Direct
N-terminal domain of adrenodoxin reductase-like0.00000005302Direct
Tudor domain0.000001057Direct
Tyrosine-dependent oxidoreductases0.00000113Direct
MaoC-like0.0001293Direct
Probable ACP-binding domain of malonyl-CoA ACP transacylase0.0006421Direct
L-aminoacid/polyamine oxidase0.000724Direct
Alcohol dehydrogenase-like, C-terminal domain0.005272Inherited
Ferredoxin domains from multidomain proteins0.01144Inherited
Alcohol dehydrogenase-like, N-terminal domain0.02143Inherited
NADPH-dependent FMN reductase0.1188Inherited
Thiolase-related0.2328Inherited
Glucose 6-phosphate dehydrogenase-like0.3164Inherited
Di-heme elbow motif0.6822Inherited
Iron-containing alcohol dehydrogenase0.8238Inherited
Aldo-keto reductases (NADP)0.936Inherited
6-phosphogluconate dehydrogenase-like, N-terminal domain1Inherited
Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain1Inherited
FAD-linked reductases, N-terminal domain1Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
Plot tree as:   Download Newick format tree:
(show help)

Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

(show details)
Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Siroheme synthase middle domains-like0Direct
Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain0Direct
Heme oxygenase-like0Direct
Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain0Direct
"Helical backbone" metal receptor0Direct
Acyl-CoA dehydrogenase NM domain-like0Direct
Uridine diphospho-N-Acetylenolpyruvylglucosamine reductase, MurB, C-terminal domain0Direct
Coproporphyrinogen III oxidase0Direct
FMN-linked oxidoreductases0Direct
alpha-helical ferredoxin0Direct
Tetrapyrrole methylase0Direct
Acyl-CoA dehydrogenase C-terminal domain-like0Direct
FAD-binding/transporter-associated domain-like0Direct
2Fe-2S ferredoxin-like0.00000000000001287Direct
FabD/lysophospholipase-like0.0000002069Direct
Chorismate mutase II0.00006663Direct
Tudor/PWWP/MBT0.0001301Direct
Probable ACP-binding domain of malonyl-CoA ACP transacylase0.0001857Direct
Nucleotide-binding domain0.00034Direct
ACP-like0.003936Inherited
Ubiquitin-like0.004735Inherited
GroES-like0.02271Inherited
FAD/NAD(P)-binding domain0.02319Inherited
ACT-like0.1483Inherited
Thioesterase/thiol ester dehydrase-isomerase0.3901Inherited
Multiheme cytochromes0.6914Inherited
NAD(P)-linked oxidoreductase0.9475Inherited
4Fe-4S ferredoxins0.9531Inherited
6-phosphogluconate dehydrogenase C-terminal domain-like1Inherited
Inosine monophosphate dehydrogenase (IMPDH)1Inherited
FAD-linked reductases, C-terminal domain1Inherited
Flavoproteins1Inherited
alpha/beta-Hydrolases1Inherited
Thiolase-like1Inherited
Dehydroquinate synthase-like1Inherited
NAD(P)-binding Rossmann-fold domains1Inherited
P-loop containing nucleoside triphosphate hydrolases1Inherited
Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain1Inherited
Radical SAM enzymes1Inherited
S-adenosyl-L-methionine-dependent methyltransferases1Inherited

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
51395,54862
  • 51395 - FMN-linked oxidoreductases
  • 54862 - 4Fe-4S ferredoxins
  • 0Direct
    47203,47203
  • 47203 - Acyl-CoA dehydrogenase C-terminal domain-like
  • 47203 - Acyl-CoA dehydrogenase C-terminal domain-like
  • 0Direct
    51735,75615
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 75615 - Siroheme synthase middle domains-like
  • 0Direct
    52151,51412
  • 52151 - FabD/lysophospholipase-like
  • 51412 - Inosine monophosphate dehydrogenase (IMPDH)
  • 0Direct
    54637,52151
  • 54637 - Thioesterase/thiol ester dehydrase-isomerase
  • 52151 - FabD/lysophospholipase-like
  • 0Direct
    75615,53790
  • 75615 - Siroheme synthase middle domains-like
  • 53790 - Tetrapyrrole methylase
  • 0Direct
    48179,55021
  • 48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like
  • 55021 - ACT-like
  • 0Direct
    56645,47203
  • 56645 - Acyl-CoA dehydrogenase NM domain-like
  • 47203 - Acyl-CoA dehydrogenase C-terminal domain-like
  • 0Direct
    51971,51395
  • 51971 - Nucleotide-binding domain
  • 51395 - FMN-linked oxidoreductases
  • 0Direct
    48600,51735
  • 48600 - Chorismate mutase II
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 0Direct
    54292,46548
  • 54292 - 2Fe-2S ferredoxin-like
  • 46548 - alpha-helical ferredoxin
  • 0Direct
    51905,56425
  • 51905 - FAD/NAD(P)-binding domain
  • 56425 - Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain
  • 0Direct
    48695,51905
  • 48695 - Multiheme cytochromes
  • 51905 - FAD/NAD(P)-binding domain
  • 0Direct
    56176,56194
  • 56176 - FAD-binding/transporter-associated domain-like
  • 56194 - Uridine diphospho-N-Acetylenolpyruvylglucosamine reductase, MurB, C-terminal domain
  • 0Direct
    47336,53474
  • 47336 - ACP-like
  • 53474 - alpha/beta-Hydrolases
  • 0.000000001062Direct
    46548,51971
  • 46548 - alpha-helical ferredoxin
  • 51971 - Nucleotide-binding domain
  • 0.000000001945Direct
    51735,51735
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 0.000002654Direct
    51971,51971
  • 51971 - Nucleotide-binding domain
  • 51971 - Nucleotide-binding domain
  • 0.000006268Direct
    51735,47336
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 47336 - ACP-like
  • 0.000006799Direct
    52151,55048
  • 52151 - FabD/lysophospholipase-like
  • 55048 - Probable ACP-binding domain of malonyl-CoA ACP transacylase
  • 0.0001857Direct
    50129,51735
  • 50129 - GroES-like
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 0.02033Inherited
    51735,50129
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 50129 - GroES-like
  • 0.284Inherited
    51735,48179
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like
  • 1Inherited
    51905,54373
  • 51905 - FAD/NAD(P)-binding domain
  • 54373 - FAD-linked reductases, C-terminal domain
  • 1Inherited
    51735,55347
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 55347 - Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain
  • 1Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    51971,51971,51395
  • 51971 - Nucleotide-binding domain
  • 51971 - Nucleotide-binding domain
  • 51395 - FMN-linked oxidoreductases
  • 0Direct
    48600,51735,48179
  • 48600 - Chorismate mutase II
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like
  • 0Direct
    48695,51905,56425
  • 48695 - Multiheme cytochromes
  • 51905 - FAD/NAD(P)-binding domain
  • 56425 - Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain
  • 0Direct
    56645,47203,47203
  • 56645 - Acyl-CoA dehydrogenase NM domain-like
  • 47203 - Acyl-CoA dehydrogenase C-terminal domain-like
  • 47203 - Acyl-CoA dehydrogenase C-terminal domain-like
  • 0Direct
    51735,48179,55021
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like
  • 55021 - ACT-like
  • 0Direct
    51735,75615,53790
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 75615 - Siroheme synthase middle domains-like
  • 53790 - Tetrapyrrole methylase
  • 0Direct
    51971,51395,54862
  • 51971 - Nucleotide-binding domain
  • 51395 - FMN-linked oxidoreductases
  • 54862 - 4Fe-4S ferredoxins
  • 0Direct
    51735,47336,53474
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 47336 - ACP-like
  • 53474 - alpha/beta-Hydrolases
  • 0.000000000005537Direct
    50129,51735,51735
  • 50129 - GroES-like
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 0.00000005579Direct
    46548,51971,51971
  • 46548 - alpha-helical ferredoxin
  • 51971 - Nucleotide-binding domain
  • 51971 - Nucleotide-binding domain
  • 0.00000006508Direct
    51735,51735,47336
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 47336 - ACP-like
  • 0.000004017Direct
    50129,51735,50129
  • 50129 - GroES-like
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 50129 - GroES-like
  • 0.2736Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
    (show help)