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Enzyme Commission (EC): With NAD(+) or NADP(+) as acceptor

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Root: EC Hierarchy (from IntEnz release 70)

Shortest distance to current term (+ for parents, - for children) EC term [EC ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + 3:   root [root] <7>
+ + 2:   Oxidoreductases [1] <26>(213|314) (212|187|94)
+ 1:   Acting on the CH-NH(2) group of donors [1.4] <9>(23|27) (23|14|4)
0:   With NAD(+) or NADP(+) as acceptor [1.4.1] <25>(11|11) (11|5|0)
- 1:   2,4-diaminopentanoate dehydrogenase [1.4.1.12](0|0) (0|0|0)
- 1:   2,4-diaminopentanoate dehydrogenase (NAD(+)) [1.4.1.26](0|0) (0|0|0)
- 1:   3-dehydroquinate synthase II [1.4.1.24](0|0) (0|0|0)
- 1:   Alanine dehydrogenase [1.4.1.1](1|2) (1|1|0)
- 1:   Aspartate dehydrogenase [1.4.1.21](1|1) (1|1|0)
- 1:   Diaminopimelate dehydrogenase [1.4.1.16](0|1) (0|0|0)
- 1:   Glutamate dehydrogenase [1.4.1.2](0|0) (0|0|0)
- 1:   Glutamate dehydrogenase (NAD(P)(+)) [1.4.1.3](1|2) (1|1|0)
- 1:   Glutamate dehydrogenase (NADP(+)) [1.4.1.4](1|2) (1|1|0)
- 1:   Glutamate synthase (NADH) [1.4.1.14](5|3) (5|0|0)
- 1:   Glutamate synthase (NADPH) [1.4.1.13](6|5) (6|2|0)
- 1:   Glycine dehydrogenase [1.4.1.10](0|0) (0|0|0)
- 1:   L-amino-acid dehydrogenase [1.4.1.5](0|0) (0|0|0)
- 1:   L-arginine dehydrogenase [1.4.1.25](0|0) (0|0|0)
- 1:   L-erythro-3,5-diaminohexanoate dehydrogenase [1.4.1.11](0|0) (0|0|0)
- 1:   Leucine dehydrogenase [1.4.1.9](0|0) (0|0|0)
- 1:   Lysine 6-dehydrogenase [1.4.1.18](0|0) (0|0|0)
- 1:   Lysine dehydrogenase [1.4.1.15](0|0) (0|0|0)
- 1:   N-methylalanine dehydrogenase [1.4.1.17](0|0) (0|0|0)
- 1:   Phenylalanine dehydrogenase [1.4.1.20](0|0) (0|0|0)
- 1:   Serine 2-dehydrogenase [1.4.1.7](0|0) (0|0|0)
- 1:   Transferred entry: 1.21.4.1 [1.4.1.6](0|0) (0|0|0)
- 1:   Tryptophan dehydrogenase [1.4.1.19](0|0) (0|0|0)
- 1:   Valine dehydrogenase (NAD(+)) [1.4.1.23](0|0) (0|0|0)
- 1:   Valine dehydrogenase (NADP(+)) [1.4.1.8](0|0) (0|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
alpha-helical ferredoxin0Direct
Formate/glycerate dehydrogenase catalytic domain-like0Direct
NAD(P)-binding Rossmann-fold domains0Direct
Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain0Direct
Aminoacid dehydrogenase-like, N-terminal domain0Direct
FMN-linked oxidoreductases0.000000192Direct
4Fe-4S ferredoxins0.0000005938Direct
Alpha subunit of glutamate synthase, C-terminal domain0.0002277Direct
N-terminal nucleophile aminohydrolases (Ntn hydrolases)0.0003928Direct
Nucleotide-binding domain0.08756Inherited
FAD/NAD(P)-binding domain1Inherited


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Family

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SCOP termFDR (all)Annotation (direct or inherited)
Aminoacid dehydrogenase-like, C-terminal domain0Direct
Aminoacid dehydrogenases0Direct
Formate/glycerate dehydrogenases, NAD-domain0Direct
L-alanine dehydrogenase-like0Direct
N-terminal domain of adrenodoxin reductase-like0Direct
Dihydrodipicolinate reductase-like0Direct
Dihydropyrimidine dehydrogenase, N-terminal domain0.00000000003621Direct
FMN-linked oxidoreductases0.0000004319Direct
Alpha subunit of glutamate synthase, C-terminal domain0.000165Direct
Class II glutamine amidotransferases0.0002858Direct
Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain0.0009244Direct


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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
alpha-helical ferredoxin0Direct
NAD(P)-binding Rossmann-fold domains0Direct
Aminoacid dehydrogenase-like, N-terminal domain0Direct
Formate/glycerate dehydrogenase catalytic domain-like0Direct
Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain0Direct
FMN-linked oxidoreductases0.0000001477Direct
4Fe-4S ferredoxins0.0000004614Direct
Alpha subunit of glutamate synthase, C-terminal domain0.0001854Direct
N-terminal nucleophile aminohydrolases (Ntn hydrolases)0.0003206Direct
Nucleotide-binding domain0.07628Inherited
FAD/NAD(P)-binding domain1Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
46548,51971
  • 46548 - alpha-helical ferredoxin
  • 51971 - Nucleotide-binding domain
  • 0Direct
    52283,51735
  • 52283 - Formate/glycerate dehydrogenase catalytic domain-like
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 0Direct
    53223,51735
  • 53223 - Aminoacid dehydrogenase-like, N-terminal domain
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 0Direct
    51735,55347
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 55347 - Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain
  • 0Direct
    54862,51395
  • 54862 - 4Fe-4S ferredoxins
  • 51395 - FMN-linked oxidoreductases
  • 0Direct


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
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