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Enzyme Commission (EC): Acting on the CH-NH group of donors

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Root: EC Hierarchy (from IntEnz release 70)

Shortest distance to current term (+ for parents, - for children) EC term [EC ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + 2:   root [root] <7>
+ 1:   Oxidoreductases [1] <26>(213|314) (212|187|94)
0:   Acting on the CH-NH group of donors [1.5] <8>(28|35) (28|14|4)
- 1:   With NAD(+) or NADP(+) as acceptor [1.5.1] <52>(17|21) (17|8|2)
- 1:   With oxygen as acceptor [1.5.3] <33>(4|5) (4|2|0)
- 1:   With other acceptors [1.5.99] <15>(2|2) (2|1|0)
- 1:   With a flavin as acceptor [1.5.8] <4>(4|4) (4|2|0)
- 1:   With a quinone or similar compound as acceptor [1.5.5] <3>(7|7) (7|4|2)
- 1:   With other, known, acceptors [1.5.98] <3>(2|2) (2|0|0)
- 1:   With an iron-sulfur protein as acceptor [1.5.7] <2>(0|0) (0|0|0)
- 1:   With a disulfide as acceptor [1.5.4] <1>(0|0) (0|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
Dihydrofolate reductase-like0Direct
FAD-linked oxidoreductase0Direct
FMN-binding split barrel0Direct
N-terminal domain of bifunctional PutA protein0Direct
NAD(P)-binding Rossmann-fold domains0Direct
Ribbon-helix-helix0Direct
F420-dependent methylenetetrahydromethanopterin dehydrogenase (MTD)0Direct
Aminoacid dehydrogenase-like, N-terminal domain0Direct
FAD-linked oxidases, C-terminal domain0Direct
Thymidylate synthase/dCMP hydroxymethylase0.000000000009653Direct
FAD-linked reductases, C-terminal domain0.00000000005454Direct
Folate-binding domain0.00000001288Direct
Aminomethyltransferase beta-barrel domain0.0000006297Direct
Electron transport accessory proteins0.00000198Direct
ACP-like0.0001529Direct
L-sulfolactate dehydrogenase-like0.0003937Direct
FMN-dependent nitroreductase-like0.03438Inherited
FMT C-terminal domain-like0.03714Inherited
Formyltransferase0.0439Inherited
4Fe-4S ferredoxins0.05814Inherited
Formate/glycerate dehydrogenase catalytic domain-like0.2357Inherited
Bacterial luciferase-like0.4397Inherited
FAD-binding/transporter-associated domain-like0.9713Inherited
Flavoproteins1Inherited
Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain1Inherited
FAD/NAD(P)-binding domain1Inherited
ALDH-like1Inherited
6-phosphogluconate dehydrogenase C-terminal domain-like1Inherited


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Family

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SCOP termFDR (all)Annotation (direct or inherited)
Aminoacid dehydrogenase-like, C-terminal domain0Direct
ProC C-terminal domain-like0Direct
N-terminal domain of bifunctional PutA protein0Direct
Ornithine cyclodeaminase-like0Direct
NADH:FMN oxidoreductase-like0Direct
Proline dehydrohenase domain of bifunctional PutA protein0Direct
Electron transfer flavoprotein-ubiquinone oxidoreductase-like0Direct
Methylenetetrahydrofolate reductase0Direct
Cytokinin dehydrogenase 10Direct
ETF-QO domain-like0Direct
Dihydrofolate reductases0Direct
Tetrahydrofolate dehydrogenase/cyclohydrolase0Direct
F420-dependent methylenetetrahydromethanopterin dehydrogenase (MTD)0Direct
R67 dihydrofolate reductase0Direct
PutA pre-N-terminal region-like0Direct
N-(1-D-carboxylethyl)-L-norvaline dehydrogenase0Direct
L-alanine dehydrogenase-like0.000000000001761Direct
FAD-linked reductases, N-terminal domain0.000000000008717Direct
FAD-linked oxidases, N-terminal domain0.00000000001828Direct
Thymidylate synthase/dCMP hydroxymethylase0.00000000001898Direct
Aminomethyltransferase beta-barrel domain0.0000009036Direct
Aminomethyltransferase folate-binding domain0.0000009382Direct
F420 dependent oxidoreductases0.000001904Direct
D-aminoacid oxidase-like0.000003214Direct
L-aminoacid/polyamine oxidase0.000005188Direct
Homoserine dehydrogenase-like0.00001537Direct
NADPH-dependent FMN reductase0.00005008Direct
L-sulfolactate dehydrogenase-like0.001651Inherited
Post formyltransferase domain0.04111Inherited
Formyltransferase0.05117Inherited
NADH oxidase/flavin reductase0.1075Inherited
6-phosphogluconate dehydrogenase-like, N-terminal domain1Inherited
Tyrosine-dependent oxidoreductases1Inherited
Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain1Inherited
ALDH-like1Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
F420-dependent methylenetetrahydromethanopterin dehydrogenase (MTD)0Direct
FMN-binding split barrel0Direct
N-terminal domain of bifunctional PutA protein0Direct
Ribbon-helix-helix0Direct
FAD-linked oxidases, C-terminal domain0Direct
Dihydrofolate reductase-like0Direct
FAD-linked oxidoreductase0Direct
NAD(P)-binding Rossmann-fold domains0Direct
Aminoacid dehydrogenase-like, N-terminal domain0Direct
Thymidylate synthase/dCMP hydroxymethylase0.00000000000699Direct
FAD-linked reductases, C-terminal domain0.00000000003988Direct
Folate-binding domain0.000000009749Direct
Aminomethyltransferase beta-barrel domain0.0000004896Direct
Electron transport accessory proteins0.000001554Direct
ACP-like0.0001241Direct
L-sulfolactate dehydrogenase-like0.0003214Direct
FMN-dependent nitroreductase-like0.02957Inherited
FMT C-terminal domain-like0.03196Inherited
Formyltransferase0.03782Inherited
4Fe-4S ferredoxins0.05041Inherited
Formate/glycerate dehydrogenase catalytic domain-like0.2101Inherited
Bacterial luciferase-like0.4001Inherited
FAD-binding/transporter-associated domain-like0.8991Inherited
6-phosphogluconate dehydrogenase C-terminal domain-like1Inherited
ALDH-like1Inherited
FAD/NAD(P)-binding domain1Inherited
Flavoproteins1Inherited
Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain1Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
51730,53720
  • 51730 - FAD-linked oxidoreductase
  • 53720 - ALDH-like
  • 0Direct
    47336,53720
  • 47336 - ACP-like
  • 53720 - ALDH-like
  • 0Direct
    81935,51730
  • 81935 - N-terminal domain of bifunctional PutA protein
  • 51730 - FAD-linked oxidoreductase
  • 0Direct
    53597,55831
  • 53597 - Dihydrofolate reductase-like
  • 55831 - Thymidylate synthase/dCMP hydroxymethylase
  • 0Direct
    50486,47336
  • 50486 - FMT C-terminal domain-like
  • 47336 - ACP-like
  • 0Direct
    47598,81935
  • 47598 - Ribbon-helix-helix
  • 81935 - N-terminal domain of bifunctional PutA protein
  • 0Direct
    53223,51735
  • 53223 - Aminoacid dehydrogenase-like, N-terminal domain
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 0Direct
    56176,55103
  • 56176 - FAD-binding/transporter-associated domain-like
  • 55103 - FAD-linked oxidases, C-terminal domain
  • 0Direct
    51905,54373
  • 51905 - FAD/NAD(P)-binding domain
  • 54373 - FAD-linked reductases, C-terminal domain
  • 0.000000000002766Direct
    103025,101790
  • 103025 - Folate-binding domain
  • 101790 - Aminomethyltransferase beta-barrel domain
  • 0.0000004896Direct
    53328,50486
  • 53328 - Formyltransferase
  • 50486 - FMT C-terminal domain-like
  • 0.02865Inherited
    52283,51735
  • 52283 - Formate/glycerate dehydrogenase catalytic domain-like
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 0.7195Inherited
    51735,48179
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like
  • 1Inherited
    51735,55347
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 55347 - Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain
  • 1Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    81935,51730,53720
  • 81935 - N-terminal domain of bifunctional PutA protein
  • 51730 - FAD-linked oxidoreductase
  • 53720 - ALDH-like
  • 0Direct
    53328,50486,47336
  • 53328 - Formyltransferase
  • 50486 - FMT C-terminal domain-like
  • 47336 - ACP-like
  • 0Direct
    47598,81935,51730
  • 47598 - Ribbon-helix-helix
  • 81935 - N-terminal domain of bifunctional PutA protein
  • 51730 - FAD-linked oxidoreductase
  • 0Direct
    50486,47336,53720
  • 50486 - FMT C-terminal domain-like
  • 47336 - ACP-like
  • 53720 - ALDH-like
  • 0Direct


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
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