SUPERFAMILY 1.75 HMM library and genome assignments server

Superfamily is undergoing a server migration - you are now browsing on the new server. Please contact us if you experience any problems.

Enzyme Commission (EC): Acting on a sulfur group of donors

(show info)

Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Root: EC Hierarchy (from IntEnz release 70)

Shortest distance to current term (+ for parents, - for children) EC term [EC ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + 2:   root [root] <7>
+ 1:   Oxidoreductases [1] <26>(213|314) (212|187|94)
0:   Acting on a sulfur group of donors [1.8] <9>(29|28) (29|21|9)
- 1:   With NAD(+) or NADP(+) as acceptor [1.8.1] <20>(11|12) (11|9|6)
- 1:   With a disulfide as acceptor [1.8.4] <14>(4|5) (4|3|1)
- 1:   With a quinone or similar compound as acceptor [1.8.5] <8>(5|4) (5|3|0)
- 1:   With oxygen as acceptor [1.8.3] <7>(8|5) (8|2|1)
- 1:   With a cytochrome as acceptor [1.8.2] <6>(1|0) (1|1|0)
- 1:   With other, known, acceptors [1.8.98] <6>(4|1) (4|1|0)
- 1:   With other acceptors [1.8.99] <5>(3|3) (3|2|1)
- 1:   With an iron-sulfur protein as acceptor [1.8.7] <3>(6|3) (6|3|2)
- 1:   With an nitrogenous group as acceptor [1.8.6] <1>(0|0) (0|0|0)


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Superfamily

(show details)
SCOP termFDR (all)Annotation (direct or inherited)
Thioredoxin-like0Direct
Nitrite and sulphite reductase 4Fe-4S domain-like0Direct
Nitrite/Sulfite reductase N-terminal domain-like0Direct
3-carboxy-cis,cis-mucoante lactonizing enzyme0Direct
FAD/NAD-linked reductases, dimerisation (C-terminal) domain0Direct
Mss4-like0Direct
FAD-dependent thiol oxidase0Direct
FAD/NAD(P)-binding domain0Direct
Peptide methionine sulfoxide reductase0Direct
Ferredoxin thioredoxin reductase (FTR), catalytic beta chain0Direct
Thiol:disulfide interchange protein DsbD, N-terminal domain (DsbD-alpha)0Direct
Adenine nucleotide alpha hydrolases-like0Direct
GST C-terminal domain-like0.000000000000001014Direct
ParB/Sulfiredoxin0.000000000000007715Direct
Riboflavin synthase domain-like0.0000000000002424Direct
Ferredoxin reductase-like, C-terminal NADP-linked domain0.0000000000004187Direct
C-type lectin-like0.0000006386Direct
Flavoproteins0.000001457Direct
Respiratory nitrate reductase 1 gamma chain0.000008057Direct
Oxidoreductase molybdopterin-binding domain0.0007977Direct
Cysteine-rich domain0.001041Inherited
alpha-helical ferredoxin0.007147Inherited
Cytochrome c0.01809Inherited
E set domains0.06492Inherited
Nucleotide-binding domain0.07483Inherited
Cytochrome b5-like heme/steroid binding domain0.1859Inherited
ADC-like0.3065Inherited
4Fe-4S ferredoxins0.3339Inherited
Formate dehydrogenase/DMSO reductase, domains 1-30.4281Inherited


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Family

(show details)
SCOP termFDR (all)Annotation (direct or inherited)
Ferredoxin thioredoxin reductase (FTR), catalytic beta chain0Direct
Sulfiredoxin-like0Direct
Nitrite and sulphite reductase 4Fe-4S domain-like0Direct
Thioltransferase0Direct
Thiol:disulfide interchange protein DsbD, N-terminal domain (DsbD-alpha)0Direct
PAPS reductase-like0Direct
NADPH-cytochrome p450 reductase-like0Direct
Peptide methionine sulfoxide reductase0Direct
NADPH-cytochrome p450 reductase FAD-binding domain-like0Direct
DsrA/DsrB N-terminal-domain-like0Direct
FAD-dependent thiol oxidase0Direct
C1-like domain0Direct
FAD/NAD-linked reductases, N-terminal and central domains0Direct
SelR domain0Direct
FAD/NAD-linked reductases, dimerisation (C-terminal) domain0Direct
Duplicated SiR/NiR-like domains 1 and 30Direct
Cytochrome p450 reductase N-terminal domain-like0Direct
Glutathione S-transferase (GST), N-terminal domain0.00000000000158Direct
Glutathione S-transferase (GST), C-terminal domain0.0000000000279Direct
Sulfatase-modifying factor-like0.0000006217Direct
Oxidoreductase molybdopterin-binding domain0.0008113Direct
Molybdenum-containing oxidoreductases-like dimerisation domain0.0009618Direct
Pyruvate-ferredoxin oxidoreductase, PFOR, domain II0.003713Inherited
Ferredoxin domains from multidomain proteins0.09793Inherited
Cytochrome b50.1582Inherited
Formate dehydrogenase/DMSO reductase, C-terminal domain0.4222Inherited
Formate dehydrogenase/DMSO reductase, domains 1-30.4275Inherited
Glutathione peroxidase-like0.7346Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
Plot tree as:   Download Newick format tree:
(show help)

Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

(show details)
Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Nitrite/Sulfite reductase N-terminal domain-like0Direct
Adenine nucleotide alpha hydrolases-like0Direct
Thioredoxin-like0Direct
FAD/NAD(P)-binding domain0Direct
Ferredoxin thioredoxin reductase (FTR), catalytic beta chain0Direct
FAD-dependent thiol oxidase0Direct
Thiol:disulfide interchange protein DsbD, N-terminal domain (DsbD-alpha)0Direct
FAD/NAD-linked reductases, dimerisation (C-terminal) domain0Direct
3-carboxy-cis,cis-mucoante lactonizing enzyme0Direct
Peptide methionine sulfoxide reductase0Direct
Mss4-like0Direct
Nitrite and sulphite reductase 4Fe-4S domain-like0Direct
GST C-terminal domain-like7.066e-16Direct
ParB/Sulfiredoxin0.000000000000005418Direct
Riboflavin synthase domain-like0.0000000000001729Direct
Ferredoxin reductase-like, C-terminal NADP-linked domain0.0000000000002996Direct
C-type lectin-like0.0000004966Direct
Flavoproteins0.00000114Direct
Respiratory nitrate reductase 1 gamma chain0.000006368Direct
Oxidoreductase molybdopterin-binding domain0.0006572Direct
Cysteine-rich domain0.0008598Direct
alpha-helical ferredoxin0.006029Inherited
Cytochrome c0.01544Inherited
E set domains0.05635Inherited
Nucleotide-binding domain0.06505Inherited
Cytochrome b5-like heme/steroid binding domain0.1646Inherited
ADC-like0.2767Inherited
4Fe-4S ferredoxins0.3017Inherited
Formate dehydrogenase/DMSO reductase, domains 1-30.3894Inherited

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
52833,55068
  • 52833 - Thioredoxin-like
  • 55068 - Peptide methionine sulfoxide reductase
  • 0Direct
    55124,54862
  • 55124 - Nitrite/Sulfite reductase N-terminal domain-like
  • 54862 - 4Fe-4S ferredoxins
  • 0Direct
    51905,55424
  • 51905 - FAD/NAD(P)-binding domain
  • 55424 - FAD/NAD-linked reductases, dimerisation (C-terminal) domain
  • 0Direct
    54862,56014
  • 54862 - 4Fe-4S ferredoxins
  • 56014 - Nitrite and sulphite reductase 4Fe-4S domain-like
  • 0Direct
    52402,52833
  • 52402 - Adenine nucleotide alpha hydrolases-like
  • 52833 - Thioredoxin-like
  • 0Direct
    55856,56524
  • 55856 - Cytochrome b5-like heme/steroid binding domain
  • 56524 - Oxidoreductase molybdopterin-binding domain
  • 0Direct
    55068,51316
  • 55068 - Peptide methionine sulfoxide reductase
  • 51316 - Mss4-like
  • 0Direct
    55124,56014
  • 55124 - Nitrite/Sulfite reductase N-terminal domain-like
  • 56014 - Nitrite and sulphite reductase 4Fe-4S domain-like
  • 0Direct
    52833,57889
  • 52833 - Thioredoxin-like
  • 57889 - Cysteine-rich domain
  • 0Direct
    56014,55124
  • 56014 - Nitrite and sulphite reductase 4Fe-4S domain-like
  • 55124 - Nitrite/Sulfite reductase N-terminal domain-like
  • 0Direct
    51905,52833
  • 51905 - FAD/NAD(P)-binding domain
  • 52833 - Thioredoxin-like
  • 0Direct
    52218,63380
  • 52218 - Flavoproteins
  • 63380 - Riboflavin synthase domain-like
  • 0Direct
    51905,54862
  • 51905 - FAD/NAD(P)-binding domain
  • 54862 - 4Fe-4S ferredoxins
  • 0Direct
    63380,52343
  • 63380 - Riboflavin synthase domain-like
  • 52343 - Ferredoxin reductase-like, C-terminal NADP-linked domain
  • 5.312e-16Direct
    52833,47616
  • 52833 - Thioredoxin-like
  • 47616 - GST C-terminal domain-like
  • 0.00000000000002662Direct
    52833,52833
  • 52833 - Thioredoxin-like
  • 52833 - Thioredoxin-like
  • 0.000000000001781Direct
    51971,51905
  • 51971 - Nucleotide-binding domain
  • 51905 - FAD/NAD(P)-binding domain
  • 0.00001125Direct
    46626,46626
  • 46626 - Cytochrome c
  • 46626 - Cytochrome c
  • 0.000187Direct
    56524,81296
  • 56524 - Oxidoreductase molybdopterin-binding domain
  • 81296 - E set domains
  • 0.0006572Direct
    53706,50692
  • 53706 - Formate dehydrogenase/DMSO reductase, domains 1-3
  • 50692 - ADC-like
  • 0.2402Inherited
    51905,51905
  • 51905 - FAD/NAD(P)-binding domain
  • 51905 - FAD/NAD(P)-binding domain
  • 0.5857Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    51971,51905,55424
  • 51971 - Nucleotide-binding domain
  • 51905 - FAD/NAD(P)-binding domain
  • 55424 - FAD/NAD-linked reductases, dimerisation (C-terminal) domain
  • 0Direct
    55124,54862,56014
  • 55124 - Nitrite/Sulfite reductase N-terminal domain-like
  • 54862 - 4Fe-4S ferredoxins
  • 56014 - Nitrite and sulphite reductase 4Fe-4S domain-like
  • 0Direct
    55856,56524,81296
  • 55856 - Cytochrome b5-like heme/steroid binding domain
  • 56524 - Oxidoreductase molybdopterin-binding domain
  • 81296 - E set domains
  • 0Direct
    55124,56014,55124
  • 55124 - Nitrite/Sulfite reductase N-terminal domain-like
  • 56014 - Nitrite and sulphite reductase 4Fe-4S domain-like
  • 55124 - Nitrite/Sulfite reductase N-terminal domain-like
  • 0Direct
    52218,63380,52343
  • 52218 - Flavoproteins
  • 63380 - Riboflavin synthase domain-like
  • 52343 - Ferredoxin reductase-like, C-terminal NADP-linked domain
  • 0Direct
    52833,55068,51316
  • 52833 - Thioredoxin-like
  • 55068 - Peptide methionine sulfoxide reductase
  • 51316 - Mss4-like
  • 0Direct
    52833,52833,57889
  • 52833 - Thioredoxin-like
  • 52833 - Thioredoxin-like
  • 57889 - Cysteine-rich domain
  • 0Direct
    56014,55124,56014
  • 56014 - Nitrite and sulphite reductase 4Fe-4S domain-like
  • 55124 - Nitrite/Sulfite reductase N-terminal domain-like
  • 56014 - Nitrite and sulphite reductase 4Fe-4S domain-like
  • 0Direct
    52833,52833,52833
  • 52833 - Thioredoxin-like
  • 52833 - Thioredoxin-like
  • 52833 - Thioredoxin-like
  • 0.000000003041Direct


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
    (show help)