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Enzyme Commission (EC): With NAD(+) or NADP(+) as acceptor

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Root: EC Hierarchy (from IntEnz release 70)

Shortest distance to current term (+ for parents, - for children) EC term [EC ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + 3:   root [root] <7>
+ + 2:   Oxidoreductases [1] <26>(213|314) (212|187|94)
+ 1:   Acting on a sulfur group of donors [1.8] <9>(29|28) (29|21|9)
0:   With NAD(+) or NADP(+) as acceptor [1.8.1] <20>(11|12) (11|9|6)
- 1:   2-oxopropyl-CoM reductase (carboxylating) [1.8.1.5](0|0) (0|0|0)
- 1:   4,4'-dithiodibutanoate disulfide reductase [1.8.1.20](0|0) (0|0|0)
- 1:   Asparagusate reductase [1.8.1.11](0|0) (0|0|0)
- 1:   Assimilatory sulfite reductase (NADPH) [1.8.1.2](5|6) (5|4|3)
- 1:   Bis-gamma-glutamylcystine reductase [1.8.1.13](0|0) (0|0|0)
- 1:   CoA-disulfide reductase [1.8.1.14](2|2) (2|1|0)
- 1:   CoA-glutathione reductase [1.8.1.10](0|0) (0|0|0)
- 1:   Cystine reductase [1.8.1.6](0|0) (0|0|0)
- 1:   Deleted entry [1.8.1.1](0|0) (0|0|0)
- 1:   Dihydrolipoyl dehydrogenase [1.8.1.4](2|2) (2|1|0)
- 1:   Dimethylsulfone reductase [1.8.1.17](0|0) (0|0|0)
- 1:   Glutathione amide reductase [1.8.1.16](0|0) (0|0|0)
- 1:   Glutathione-disulfide reductase [1.8.1.7](2|2) (2|1|0)
- 1:   Hypotaurine dehydrogenase [1.8.1.3](0|0) (0|0|0)
- 1:   Mycothione reductase [1.8.1.15](0|0) (0|0|0)
- 1:   NAD(P)H sulfur oxidoreductase (CoA-dependent) [1.8.1.18](0|0) (0|0|0)
- 1:   Protein-disulfide reductase [1.8.1.8](3|4) (3|2|2)
- 1:   Sulfide dehydrogenase [1.8.1.19](0|0) (0|0|0)
- 1:   Thioredoxin-disulfide reductase [1.8.1.9](1|1) (1|1|0)
- 1:   Trypanothione-disulfide reductase [1.8.1.12](1|0) (1|1|1)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
Nitrite and sulphite reductase 4Fe-4S domain-like0Direct
Nitrite/Sulfite reductase N-terminal domain-like0Direct
Ferredoxin reductase-like, C-terminal NADP-linked domain0Direct
Flavoproteins0Direct
Riboflavin synthase domain-like0Direct
FAD/NAD-linked reductases, dimerisation (C-terminal) domain0Direct
FAD/NAD(P)-binding domain0Direct
Thiol:disulfide interchange protein DsbD, N-terminal domain (DsbD-alpha)0Direct
Nucleotide-binding domain0.00000001018Direct
Thioredoxin-like0.000003539Direct
Cysteine-rich domain0.000008431Direct


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Family

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SCOP termFDR (all)Annotation (direct or inherited)
Nitrite and sulphite reductase 4Fe-4S domain-like0Direct
Thiol:disulfide interchange protein DsbD, N-terminal domain (DsbD-alpha)0Direct
NADPH-cytochrome p450 reductase-like0Direct
NADPH-cytochrome p450 reductase FAD-binding domain-like0Direct
C1-like domain0Direct
FAD/NAD-linked reductases, N-terminal and central domains0Direct
FAD/NAD-linked reductases, dimerisation (C-terminal) domain0Direct
Duplicated SiR/NiR-like domains 1 and 30Direct
Cytochrome p450 reductase N-terminal domain-like0Direct
Thioltransferase0.000000000000002552Direct
Pyruvate-ferredoxin oxidoreductase, PFOR, domain II0.000000004401Direct
Glutathione peroxidase-like0.001147Inherited


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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Nitrite/Sulfite reductase N-terminal domain-like0Direct
FAD/NAD(P)-binding domain0Direct
Flavoproteins0Direct
Thiol:disulfide interchange protein DsbD, N-terminal domain (DsbD-alpha)0Direct
Riboflavin synthase domain-like0Direct
FAD/NAD-linked reductases, dimerisation (C-terminal) domain0Direct
Ferredoxin reductase-like, C-terminal NADP-linked domain0Direct
Nitrite and sulphite reductase 4Fe-4S domain-like0Direct
Nucleotide-binding domain0.000000007699Direct
Thioredoxin-like0.000002785Direct
Cysteine-rich domain0.000006667Direct

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
52833,52833
  • 52833 - Thioredoxin-like
  • 52833 - Thioredoxin-like
  • 0Direct
    51905,55424
  • 51905 - FAD/NAD(P)-binding domain
  • 55424 - FAD/NAD-linked reductases, dimerisation (C-terminal) domain
  • 0Direct
    63380,52343
  • 63380 - Riboflavin synthase domain-like
  • 52343 - Ferredoxin reductase-like, C-terminal NADP-linked domain
  • 0Direct
    55124,56014
  • 55124 - Nitrite/Sulfite reductase N-terminal domain-like
  • 56014 - Nitrite and sulphite reductase 4Fe-4S domain-like
  • 0Direct
    52833,57889
  • 52833 - Thioredoxin-like
  • 57889 - Cysteine-rich domain
  • 0Direct
    56014,55124
  • 56014 - Nitrite and sulphite reductase 4Fe-4S domain-like
  • 55124 - Nitrite/Sulfite reductase N-terminal domain-like
  • 0Direct
    51905,52833
  • 51905 - FAD/NAD(P)-binding domain
  • 52833 - Thioredoxin-like
  • 0Direct
    52218,63380
  • 52218 - Flavoproteins
  • 63380 - Riboflavin synthase domain-like
  • 0Direct
    51971,51905
  • 51971 - Nucleotide-binding domain
  • 51905 - FAD/NAD(P)-binding domain
  • 0.0000000000004099Direct

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    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    51971,51905,55424
  • 51971 - Nucleotide-binding domain
  • 51905 - FAD/NAD(P)-binding domain
  • 55424 - FAD/NAD-linked reductases, dimerisation (C-terminal) domain
  • 0Direct
    55124,56014,55124
  • 55124 - Nitrite/Sulfite reductase N-terminal domain-like
  • 56014 - Nitrite and sulphite reductase 4Fe-4S domain-like
  • 55124 - Nitrite/Sulfite reductase N-terminal domain-like
  • 0Direct
    52218,63380,52343
  • 52218 - Flavoproteins
  • 63380 - Riboflavin synthase domain-like
  • 52343 - Ferredoxin reductase-like, C-terminal NADP-linked domain
  • 0Direct
    52833,52833,57889
  • 52833 - Thioredoxin-like
  • 52833 - Thioredoxin-like
  • 57889 - Cysteine-rich domain
  • 0Direct
    56014,55124,56014
  • 56014 - Nitrite and sulphite reductase 4Fe-4S domain-like
  • 55124 - Nitrite/Sulfite reductase N-terminal domain-like
  • 56014 - Nitrite and sulphite reductase 4Fe-4S domain-like
  • 0Direct
    52833,52833,52833
  • 52833 - Thioredoxin-like
  • 52833 - Thioredoxin-like
  • 52833 - Thioredoxin-like
  • 0.00000000000119Direct


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
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