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Enzyme Commission (EC): Histone-lysine N-methyltransferase

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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Root: EC Hierarchy (from IntEnz release 70)

Shortest distance to current term (+ for parents, - for children) EC term [EC ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + 4:   root [root] <7>
+ + + 3:   Transferases [2] <10>(448|683) (447|545|278)
+ + 2:   Transferring one-carbon groups [2.1] <5>(86|125) (86|80|30)
+ 1:   Methyltransferases [2.1.1] <369>(66|102) (66|60|14)
0:   Histone-lysine N-methyltransferase [2.1.1.43](16|15) (16|14|5)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
HMG-box0Direct
SET domain0Direct
KRAB domain (Kruppel-associated box)0Direct
FYVE/PHD zinc finger0Direct
DNA-binding domain0Direct
RNA-binding domain, RBD0Direct
Chromo domain-like0Direct
beta-beta-alpha zinc fingers0Direct
WW domain0Direct
Conserved domain common to transcription factors TFIIS, elongin A, CRSP700Direct
Tudor/PWWP/MBT0Direct
Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain0.0000000000001626Direct
TPR-like0.00000000001834Direct
Bromodomain0.0000000001676Direct
Ankyrin repeat0.000006107Direct
PUA domain-like0.00009997Direct


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Family

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SCOP termFDR (all)Annotation (direct or inherited)
Histone lysine methyltransferases0Direct
KRAB domain (Kruppel-associated box)0Direct
SRA domain-like0Direct
Catalytic, N-terminal domain of histone methyltransferase Dot1l0Direct
PHD domain0Direct
WW domain0Direct
PWWP domain0Direct
HMG-box0Direct
Chromo domain0Direct
Conserved domain common to transcription factors TFIIS, elongin A, CRSP700Direct
Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain0.00000000000002334Direct
Canonical RBD0.000000000008285Direct
Classic zinc finger, C2H20.00000000003128Direct
Bromodomain0.00000000003957Direct
Ankyrin repeat0.000001791Direct


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
DNA-binding domain0Direct
HMG-box0Direct
Tudor/PWWP/MBT0Direct
SET domain0Direct
Conserved domain common to transcription factors TFIIS, elongin A, CRSP700Direct
Chromo domain-like0Direct
beta-beta-alpha zinc fingers0Direct
FYVE/PHD zinc finger0Direct
WW domain0Direct
KRAB domain (Kruppel-associated box)0Direct
RNA-binding domain, RBD0Direct
Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain0.0000000000001155Direct
TPR-like0.00000000001333Direct
Bromodomain0.0000000001236Direct
Ankyrin repeat0.000004814Direct
PUA domain-like0.00008074Direct

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
57903,63748
  • 57903 - FYVE/PHD zinc finger
  • 63748 - Tudor/PWWP/MBT
  • 0Direct
    57667,57667
  • 57667 - beta-beta-alpha zinc fingers
  • 57667 - beta-beta-alpha zinc fingers
  • 0Direct
    82185,82199
  • 82185 - Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain
  • 82199 - SET domain
  • 0Direct
    57903,57903
  • 57903 - FYVE/PHD zinc finger
  • 57903 - FYVE/PHD zinc finger
  • 0Direct
    57903,82199
  • 57903 - FYVE/PHD zinc finger
  • 82199 - SET domain
  • 0Direct
    63748,82199
  • 63748 - Tudor/PWWP/MBT
  • 82199 - SET domain
  • 0Direct
    82199,48452
  • 82199 - SET domain
  • 48452 - TPR-like
  • 0Direct
    82199,57903
  • 82199 - SET domain
  • 57903 - FYVE/PHD zinc finger
  • 0Direct
    54160,82199
  • 54160 - Chromo domain-like
  • 82199 - SET domain
  • 0Direct
    48403,82199
  • 48403 - Ankyrin repeat
  • 82199 - SET domain
  • 0Direct
    88697,82199
  • 88697 - PUA domain-like
  • 82199 - SET domain
  • 0Direct
    82199,57667
  • 82199 - SET domain
  • 57667 - beta-beta-alpha zinc fingers
  • 0Direct
    54171,82199
  • 54171 - DNA-binding domain
  • 82199 - SET domain
  • 0Direct
    57903,47370
  • 57903 - FYVE/PHD zinc finger
  • 47370 - Bromodomain
  • 0.0000000008054Direct

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    57903,63748,82199
  • 57903 - FYVE/PHD zinc finger
  • 63748 - Tudor/PWWP/MBT
  • 82199 - SET domain
  • 0Direct
    57667,57667,57667
  • 57667 - beta-beta-alpha zinc fingers
  • 57667 - beta-beta-alpha zinc fingers
  • 57667 - beta-beta-alpha zinc fingers
  • 0Direct
    57903,57903,57903
  • 57903 - FYVE/PHD zinc finger
  • 57903 - FYVE/PHD zinc finger
  • 57903 - FYVE/PHD zinc finger
  • 0Direct
    82199,57667,57667
  • 82199 - SET domain
  • 57667 - beta-beta-alpha zinc fingers
  • 57667 - beta-beta-alpha zinc fingers
  • 0Direct
    63748,82199,57903
  • 63748 - Tudor/PWWP/MBT
  • 82199 - SET domain
  • 57903 - FYVE/PHD zinc finger
  • 0Direct


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
    (show help)