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Enzyme Commission (EC): DNA-directed DNA polymerase

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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Root: EC Hierarchy (from IntEnz release 70)

Shortest distance to current term (+ for parents, - for children) EC term [EC ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + 4:   root [root] <7>
+ + + 3:   Transferases [2] <10>(448|683) (447|545|278)
+ + 2:   Transferring phosphorus-containing groups [2.7] <15>(256|338) (255|318|190)
+ 1:   Nucleotidyltransferases [2.7.7] <109>(102|127) (102|101|68)
0:   DNA-directed DNA polymerase [2.7.7.7](23|32) (23|30|26)


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
Acid proteases0Direct
PsbU/PolX domain-like0Direct
Retrovirus zinc finger-like domains0Direct
PHP domain-like0Direct
PIN domain-like0Direct
AF1531-like0Direct
Retrovirus capsid dimerization domain-like0Direct
Retroviral matrix proteins0Direct
5' to 3' exonuclease, C-terminal subdomain0Direct
Retrovirus capsid protein, N-terminal core domain0Direct
DNA polymerase III chi subunit0Direct
Lesion bypass DNA polymerase (Y-family), little finger domain0Direct
DNA-binding domain of retroviral integrase0Direct
Zinc finger domain of DNA polymerase-alpha0Direct
Ribonuclease H-like0Direct
post-AAA+ oligomerization domain-like0Direct
DNA/RNA polymerases0Direct
N-terminal Zn binding domain of HIV integrase0Direct
Hedgehog/intein (Hint) domain0Direct
DNA polymerase beta, N-terminal domain-like0.000000000000042Direct
Homing endonucleases0.00000000000008385Direct
Sec63 N-terminal domain-like0.00001794Direct
dUTPase-like0.0001592Direct


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Family

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SCOP termFDR (all)Annotation (direct or inherited)
DNA polymerase III clamp loader subunits, C-terminal domain0Direct
Retroviral protease (retropepsin)0Direct
Lesion bypass DNA polymerase (Y-family), little finger domain0Direct
MMLV matrix protein-like0Direct
Retroviral integrase, catalytic domain0Direct
N-terminal Zn binding domain of HIV integrase0Direct
Ribonuclease H0Direct
5' to 3' exonuclease, C-terminal subdomain0Direct
Retrovirus zinc finger-like domains0Direct
Retrovirus capsid protein, N-terminal core domain0Direct
DNA polymerase III chi subunit0Direct
Mason-Pfizer monkey virus matrix protein0Direct
DNA polymerase beta-like0Direct
Reverse transcriptase0Direct
Lesion bypass DNA polymerase (Y-family), catalytic domain0Direct
Retrovirus capsid protein C-terminal domain0Direct
PHP domain0Direct
GAG polyprotein M-domain0Direct
Immunodeficiency virus matrix proteins0Direct
Zinc finger domain of DNA polymerase-alpha0Direct
DnaQ-like 3'-5' exonuclease0Direct
DNA-binding domain of retroviral integrase0Direct
AF1531-like0Direct
HTLV-II matrix protein0Direct
5' to 3' exonuclease catalytic domain0Direct
DNA polymerase I0Direct
DNA polymerase beta, N-terminal domain-like0.000000000000004718Direct
DNA polymerase beta-like, second domain0.0000000000003374Direct
Intein (protein splicing domain)0.00000000002217Direct
Extended AAA-ATPase domain0.0000000002245Direct
Achaeal helicase C-terminal domain0.0000005297Direct
dUTPase-like0.00003104Direct


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Hedgehog/intein (Hint) domain0Direct
post-AAA+ oligomerization domain-like0Direct
Retrovirus capsid dimerization domain-like0Direct
Ribonuclease H-like0Direct
Lesion bypass DNA polymerase (Y-family), little finger domain0Direct
DNA polymerase III chi subunit0Direct
Acid proteases0Direct
AF1531-like0Direct
N-terminal Zn binding domain of HIV integrase0Direct
PHP domain-like0Direct
5' to 3' exonuclease, C-terminal subdomain0Direct
Retrovirus capsid protein, N-terminal core domain0Direct
Retroviral matrix proteins0Direct
Zinc finger domain of DNA polymerase-alpha0Direct
PsbU/PolX domain-like0Direct
DNA-binding domain of retroviral integrase0Direct
DNA/RNA polymerases0Direct
PIN domain-like0Direct
Retrovirus zinc finger-like domains0Direct
DNA polymerase beta, N-terminal domain-like0.00000000000002971Direct
Homing endonucleases0.00000000000005955Direct
Sec63 N-terminal domain-like0.0000143Direct
dUTPase-like0.0001292Direct

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
47807,56672
  • 47807 - 5' to 3' exonuclease, C-terminal subdomain
  • 56672 - DNA/RNA polymerases
  • 0Direct
    56672,55608
  • 56672 - DNA/RNA polymerases
  • 55608 - Homing endonucleases
  • 0Direct
    53098,56672
  • 53098 - Ribonuclease H-like
  • 56672 - DNA/RNA polymerases
  • 0Direct
    47807,53098
  • 47807 - 5' to 3' exonuclease, C-terminal subdomain
  • 53098 - Ribonuclease H-like
  • 0Direct
    47836,47943
  • 47836 - Retroviral matrix proteins
  • 47943 - Retrovirus capsid protein, N-terminal core domain
  • 0Direct
    56672,100879
  • 56672 - DNA/RNA polymerases
  • 100879 - Lesion bypass DNA polymerase (Y-family), little finger domain
  • 0Direct
    53098,46919
  • 53098 - Ribonuclease H-like
  • 46919 - N-terminal Zn binding domain of HIV integrase
  • 0Direct
    51283,50630
  • 51283 - dUTPase-like
  • 50630 - Acid proteases
  • 0Direct
    88723,47807
  • 88723 - PIN domain-like
  • 47807 - 5' to 3' exonuclease, C-terminal subdomain
  • 0Direct
    50630,56672
  • 50630 - Acid proteases
  • 56672 - DNA/RNA polymerases
  • 0Direct
    56672,53098
  • 56672 - DNA/RNA polymerases
  • 53098 - Ribonuclease H-like
  • 0Direct
    52540,48019
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 48019 - post-AAA+ oligomerization domain-like
  • 0Direct
    50249,89550
  • 50249 - Nucleic acid-binding proteins
  • 89550 - PHP domain-like
  • 0Direct
    53098,50122
  • 53098 - Ribonuclease H-like
  • 50122 - DNA-binding domain of retroviral integrase
  • 0Direct
    57756,51283
  • 57756 - Retrovirus zinc finger-like domains
  • 51283 - dUTPase-like
  • 0Direct
    56672,51294
  • 56672 - DNA/RNA polymerases
  • 51294 - Hedgehog/intein (Hint) domain
  • 0Direct
    46919,53098
  • 46919 - N-terminal Zn binding domain of HIV integrase
  • 53098 - Ribonuclease H-like
  • 0Direct
    47943,47353
  • 47943 - Retrovirus capsid protein, N-terminal core domain
  • 47353 - Retrovirus capsid dimerization domain-like
  • 0Direct
    57756,50630
  • 57756 - Retrovirus zinc finger-like domains
  • 50630 - Acid proteases
  • 0Direct
    50249,56300
  • 50249 - Nucleic acid-binding proteins
  • 56300 - Metallo-dependent phosphatases
  • 0Direct
    56672,46919
  • 56672 - DNA/RNA polymerases
  • 46919 - N-terminal Zn binding domain of HIV integrase
  • 0Direct
    51294,56672
  • 51294 - Hedgehog/intein (Hint) domain
  • 56672 - DNA/RNA polymerases
  • 0Direct
    55608,56672
  • 55608 - Homing endonucleases
  • 56672 - DNA/RNA polymerases
  • 0Direct
    47353,57756
  • 47353 - Retrovirus capsid dimerization domain-like
  • 57756 - Retrovirus zinc finger-like domains
  • 0Direct
    56672,90234
  • 56672 - DNA/RNA polymerases
  • 90234 - Zinc finger domain of DNA polymerase-alpha
  • 0Direct
    53098,53098
  • 53098 - Ribonuclease H-like
  • 53098 - Ribonuclease H-like
  • 0Direct
    89550,53098
  • 89550 - PHP domain-like
  • 53098 - Ribonuclease H-like
  • 0Direct
    81585,81301
  • 81585 - PsbU/PolX domain-like
  • 81301 - Nucleotidyltransferase
  • 0.000000000001702Direct
    47802,81585
  • 47802 - DNA polymerase beta, N-terminal domain-like
  • 81585 - PsbU/PolX domain-like
  • 0.000000000001702Direct
    57756,57756
  • 57756 - Retrovirus zinc finger-like domains
  • 57756 - Retrovirus zinc finger-like domains
  • 0.000004899Direct

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    47353,57756,50630
  • 47353 - Retrovirus capsid dimerization domain-like
  • 57756 - Retrovirus zinc finger-like domains
  • 50630 - Acid proteases
  • 0Direct
    51294,56672,55608
  • 51294 - Hedgehog/intein (Hint) domain
  • 56672 - DNA/RNA polymerases
  • 55608 - Homing endonucleases
  • 0Direct
    53098,56672,90234
  • 53098 - Ribonuclease H-like
  • 56672 - DNA/RNA polymerases
  • 90234 - Zinc finger domain of DNA polymerase-alpha
  • 0Direct
    50630,56672,53098
  • 50630 - Acid proteases
  • 56672 - DNA/RNA polymerases
  • 53098 - Ribonuclease H-like
  • 0Direct
    53098,56672,51294
  • 53098 - Ribonuclease H-like
  • 56672 - DNA/RNA polymerases
  • 51294 - Hedgehog/intein (Hint) domain
  • 0Direct
    47943,47353,57756
  • 47943 - Retrovirus capsid protein, N-terminal core domain
  • 47353 - Retrovirus capsid dimerization domain-like
  • 57756 - Retrovirus zinc finger-like domains
  • 0Direct
    57756,50630,56672
  • 57756 - Retrovirus zinc finger-like domains
  • 50630 - Acid proteases
  • 56672 - DNA/RNA polymerases
  • 0Direct
    46919,53098,50122
  • 46919 - N-terminal Zn binding domain of HIV integrase
  • 53098 - Ribonuclease H-like
  • 50122 - DNA-binding domain of retroviral integrase
  • 0Direct
    55608,56672,51294
  • 55608 - Homing endonucleases
  • 56672 - DNA/RNA polymerases
  • 51294 - Hedgehog/intein (Hint) domain
  • 0Direct
    56672,53098,53098
  • 56672 - DNA/RNA polymerases
  • 53098 - Ribonuclease H-like
  • 53098 - Ribonuclease H-like
  • 0Direct
    57756,51283,50630
  • 57756 - Retrovirus zinc finger-like domains
  • 51283 - dUTPase-like
  • 50630 - Acid proteases
  • 0Direct
    88723,47807,56672
  • 88723 - PIN domain-like
  • 47807 - 5' to 3' exonuclease, C-terminal subdomain
  • 56672 - DNA/RNA polymerases
  • 0Direct
    56672,46919,53098
  • 56672 - DNA/RNA polymerases
  • 46919 - N-terminal Zn binding domain of HIV integrase
  • 53098 - Ribonuclease H-like
  • 0Direct
    56672,55608,56672
  • 56672 - DNA/RNA polymerases
  • 55608 - Homing endonucleases
  • 56672 - DNA/RNA polymerases
  • 0Direct
    50630,56672,46919
  • 50630 - Acid proteases
  • 56672 - DNA/RNA polymerases
  • 46919 - N-terminal Zn binding domain of HIV integrase
  • 0Direct
    47807,53098,56672
  • 47807 - 5' to 3' exonuclease, C-terminal subdomain
  • 53098 - Ribonuclease H-like
  • 56672 - DNA/RNA polymerases
  • 0Direct
    56672,53098,50122
  • 56672 - DNA/RNA polymerases
  • 53098 - Ribonuclease H-like
  • 50122 - DNA-binding domain of retroviral integrase
  • 0Direct
    50249,89550,53098
  • 50249 - Nucleic acid-binding proteins
  • 89550 - PHP domain-like
  • 53098 - Ribonuclease H-like
  • 0Direct
    47836,47943,47353
  • 47836 - Retroviral matrix proteins
  • 47943 - Retrovirus capsid protein, N-terminal core domain
  • 47353 - Retrovirus capsid dimerization domain-like
  • 0Direct
    56672,53098,46919
  • 56672 - DNA/RNA polymerases
  • 53098 - Ribonuclease H-like
  • 46919 - N-terminal Zn binding domain of HIV integrase
  • 0Direct
    53098,46919,53098
  • 53098 - Ribonuclease H-like
  • 46919 - N-terminal Zn binding domain of HIV integrase
  • 53098 - Ribonuclease H-like
  • 0Direct
    51283,50630,56672
  • 51283 - dUTPase-like
  • 50630 - Acid proteases
  • 56672 - DNA/RNA polymerases
  • 0Direct
    88723,47807,53098
  • 88723 - PIN domain-like
  • 47807 - 5' to 3' exonuclease, C-terminal subdomain
  • 53098 - Ribonuclease H-like
  • 0Direct
    47802,81585,81301
  • 47802 - DNA polymerase beta, N-terminal domain-like
  • 81585 - PsbU/PolX domain-like
  • 81301 - Nucleotidyltransferase
  • 0.000000000001702Direct
    47353,57756,57756
  • 47353 - Retrovirus capsid dimerization domain-like
  • 57756 - Retrovirus zinc finger-like domains
  • 57756 - Retrovirus zinc finger-like domains
  • 0.000000000002327Direct
    57756,57756,51283
  • 57756 - Retrovirus zinc finger-like domains
  • 57756 - Retrovirus zinc finger-like domains
  • 51283 - dUTPase-like
  • 0.000000000002327Direct


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
    (show help)