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Enzyme Commission (EC): Protein-tyrosine-phosphatase

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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Root: EC Hierarchy (from IntEnz release 70)

Shortest distance to current term (+ for parents, - for children) EC term [EC ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + 4:   root [root] <7>
+ + + 3:   Hydrolases [3] <13>(396|669) (395|421|209)
+ + 2:   Acting on ester bonds [3.1] <23>(157|226) (157|126|55)
+ 1:   Phosphoric monoester hydrolases [3.1.3] <112>(60|78) (60|45|12)
0:   Protein-tyrosine-phosphatase [3.1.3.48](21|23) (21|19|9)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
Bacterial GAP domain0Direct
(Phosphotyrosine protein) phosphatases II0Direct
CRAL/TRIO N-terminal domain0Direct
Phosphotyrosine protein phosphatases I0Direct
Fibronectin type III0Direct
Immunoglobulin0Direct
Second domain of FERM0Direct
DEK C-terminal domain0Direct
Rhodanese/Cell cycle control phosphatase0Direct
PDZ domain-like0.0000000009357Direct
Chaperone J-domain0.000000001194Direct
Carbonic anhydrase0.000000009897Direct
CRAL/TRIO domain0.00000001591Direct
Non-globular alpha+beta subunits of globular proteins0.0000002184Direct
Concanavalin A-like lectins/glucanases0.0000003927Direct
FYVE/PHD zinc finger0.0000004201Direct
Ubiquitin-like0.000001851Direct
C2 domain (Calcium/lipid-binding domain, CaLB)0.00005675Direct
SH2 domain0.00005675Direct
Starch-binding domain-like0.0001137Direct
PH domain-like0.0002048Direct


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Family

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SCOP termFDR (all)Annotation (direct or inherited)
Cell cycle control phosphatase, catalytic domain0Direct
First domain of FERM0Direct
Second domain of FERM0Direct
MAM domain0Direct
CRAL/TRIO N-terminal domain0Direct
Dual specificity phosphatase-like0Direct
Fibronectin type III0Direct
I set domains0Direct
Third domain of FERM0Direct
Low-molecular-weight phosphotyrosine protein phosphatases0Direct
Bacterial GAP domain0Direct
Magnesium-dependent phosphatase-1, Mdp10Direct
CRAL/TRIO domain0Direct
Virulence effector SptP domain0Direct
Higher-molecular-weight phosphotyrosine protein phosphatases0Direct
PDZ domain0.000000000000001826Direct
DEK C-terminal domain0.000000000000003816Direct
FYVE, a phosphatidylinositol-3-phosphate binding domain0.000000000000005616Direct
Chaperone J-domain0.000000001052Direct
Carbonic anhydrase0.000000009031Direct
PLC-like (P variant)0.0000000188Direct
SH2 domain0.0000697Direct
Starch-binding domain0.0007233Direct


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
(Phosphotyrosine protein) phosphatases II0Direct
Immunoglobulin0Direct
Phosphotyrosine protein phosphatases I0Direct
CRAL/TRIO N-terminal domain0Direct
DEK C-terminal domain0Direct
Rhodanese/Cell cycle control phosphatase0Direct
Bacterial GAP domain0Direct
Second domain of FERM0Direct
Fibronectin type III0Direct
PDZ domain-like0.0000000006963Direct
Chaperone J-domain0.0000000008903Direct
Carbonic anhydrase0.000000007467Direct
CRAL/TRIO domain0.00000001203Direct
Non-globular alpha+beta subunits of globular proteins0.0000001678Direct
Concanavalin A-like lectins/glucanases0.0000003033Direct
FYVE/PHD zinc finger0.0000003247Direct
Ubiquitin-like0.00000145Direct
SH2 domain0.00004549Direct
C2 domain (Calcium/lipid-binding domain, CaLB)0.00004549Direct
Starch-binding domain-like0.00009187Direct
PH domain-like0.0001662Direct

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
52821,52799
  • 52821 - Rhodanese/Cell cycle control phosphatase
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 0Direct
    47031,50729
  • 47031 - Second domain of FERM
  • 50729 - PH domain-like
  • 0Direct
    52087,52799
  • 52087 - CRAL/TRIO domain
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 0Direct
    52799,52799
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 0Direct
    56568,47233
  • 56568 - Non-globular alpha+beta subunits of globular proteins
  • 47233 - Bacterial GAP domain
  • 0Direct
    49899,48726
  • 49899 - Concanavalin A-like lectins/glucanases
  • 48726 - Immunoglobulin
  • 0Direct
    49265,49265
  • 49265 - Fibronectin type III
  • 49265 - Fibronectin type III
  • 0Direct
    51069,49265
  • 51069 - Carbonic anhydrase
  • 49265 - Fibronectin type III
  • 0Direct
    46938,52087
  • 46938 - CRAL/TRIO N-terminal domain
  • 52087 - CRAL/TRIO domain
  • 0Direct
    48726,49265
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 0Direct
    47233,52799
  • 47233 - Bacterial GAP domain
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 0Direct
    50156,52799
  • 50156 - PDZ domain-like
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 0Direct
    55550,52799
  • 55550 - SH2 domain
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 0Direct
    49452,52799
  • 49452 - Starch-binding domain-like
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 0Direct
    48726,48726
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 0Direct
    54236,47031
  • 54236 - Ubiquitin-like
  • 47031 - Second domain of FERM
  • 0Direct
    109715,52799
  • 109715 - DEK C-terminal domain
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 0Direct
    55550,55550
  • 55550 - SH2 domain
  • 55550 - SH2 domain
  • 0Direct
    52799,49562
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 0.00000001148Direct

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    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    49265,49265,49265
  • 49265 - Fibronectin type III
  • 49265 - Fibronectin type III
  • 49265 - Fibronectin type III
  • 0Direct
    56568,47233,52799
  • 56568 - Non-globular alpha+beta subunits of globular proteins
  • 47233 - Bacterial GAP domain
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 0Direct
    48726,49265,49265
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 49265 - Fibronectin type III
  • 0Direct
    55550,55550,52799
  • 55550 - SH2 domain
  • 55550 - SH2 domain
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 0Direct
    48726,48726,48726
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 0Direct
    49899,48726,49265
  • 49899 - Concanavalin A-like lectins/glucanases
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 0Direct
    48726,48726,49265
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 0Direct
    54236,47031,50729
  • 54236 - Ubiquitin-like
  • 47031 - Second domain of FERM
  • 50729 - PH domain-like
  • 0Direct
    46938,52087,52799
  • 46938 - CRAL/TRIO N-terminal domain
  • 52087 - CRAL/TRIO domain
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 0Direct


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
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