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Enzyme Commission (EC): Aminopeptidases

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Root: EC Hierarchy (from IntEnz release 70)

Shortest distance to current term (+ for parents, - for children) EC term [EC ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + 3:   root [root] <7>
+ + 2:   Hydrolases [3] <13>(395|668) (394|417|206)
+ 1:   Acting on peptide bonds (peptidases) [3.4] <19>(114|168) (114|129|72)
0:   Aminopeptidases [3.4.11] <27>(14|15) (14|11|3)
- 1:   Aminopeptidase B [3.4.11.6](3|3) (3|2|1)
- 1:   Aminopeptidase Ey [3.4.11.20](0|0) (0|0|0)
- 1:   Aminopeptidase I [3.4.11.22](0|0) (0|0|0)
- 1:   Aminopeptidase S [3.4.11.24](0|0) (0|0|0)
- 1:   Aminopeptidase Y [3.4.11.15](0|0) (0|0|0)
- 1:   Aspartyl aminopeptidase [3.4.11.21](1|2) (1|1|0)
- 1:   Bacterial leucyl aminopeptidase [3.4.11.10](2|2) (2|1|0)
- 1:   Beta-peptidyl aminopeptidase [3.4.11.25](0|0) (0|0|0)
- 1:   Clostridial aminopeptidase [3.4.11.13](0|0) (0|0|0)
- 1:   Cystinyl aminopeptidase [3.4.11.3](2|2) (2|1|0)
- 1:   Cytosol alanyl aminopeptidase [3.4.11.14](2|2) (2|1|0)
- 1:   D-stereospecific aminopeptidase [3.4.11.19](2|2) (2|2|1)
- 1:   Deleted entry [3.4.11.12](0|0) (0|0|0)
- 1:   Deleted entry [3.4.11.11](0|0) (0|0|0)
- 1:   Glutamyl aminopeptidase [3.4.11.7](2|2) (2|1|0)
- 1:   Intermediate cleaving peptidase 55 [3.4.11.26](0|0) (0|0|0)
- 1:   Leucyl aminopeptidase [3.4.11.1](2|2) (2|1|0)
- 1:   Membrane alanyl aminopeptidase [3.4.11.2](2|2) (2|1|0)
- 1:   Methionyl aminopeptidase [3.4.11.18](3|3) (3|2|0)
- 1:   PepB aminopeptidase [3.4.11.23](1|1) (1|0|0)
- 1:   Prolyl aminopeptidase [3.4.11.5](1|1) (1|0|0)
- 1:   Transferred entry: 3.4.11.24 [3.4.11.n1](0|0) (0|0|0)
- 1:   Transferred entry: 3.4.19.3 [3.4.11.8](0|0) (0|0|0)
- 1:   Tripeptide aminopeptidase [3.4.11.4](2|2) (2|1|0)
- 1:   Tryptophanyl aminopeptidase [3.4.11.17](0|0) (0|0|0)
- 1:   Xaa-Pro aminopeptidase [3.4.11.9](2|2) (2|2|1)
- 1:   Xaa-Trp aminopeptidase [3.4.11.16](0|0) (0|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
Creatinase/prolidase N-terminal domain0Direct
Creatinase/aminopeptidase0Direct
Aminopeptidase/glucanase lid domain0Direct
Macro domain-like0Direct
D-aminopeptidase, middle and C-terminal domains0Direct
Zn-dependent exopeptidases0Direct
Leukotriene A4 hydrolase N-terminal domain0Direct
Bacterial exopeptidase dimerisation domain0Direct
"Winged helix" DNA-binding domain0.0000751Direct
Sec-C motif0.0008781Direct
ARM repeat0.007348Inherited
alpha/beta-Hydrolases1Inherited
beta-lactamase/transpeptidase-like1Inherited
Metalloproteases ("zincins"), catalytic domain1Inherited


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Family

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SCOP termFDR (all)Annotation (direct or inherited)
Aminopeptidase/glucanase lid domain0Direct
Proline iminopeptidase-like0Direct
Leukotriene A4 hydrolase N-terminal domain0Direct
Bacterial exopeptidase dimerisation domain0Direct
Creatinase/aminopeptidase0Direct
D-aminopeptidase, middle and C-terminal domains0Direct
Methionine aminopeptidase, insert domain0Direct
Leucine aminopeptidase (Aminopeptidase A), N-terminal domain0Direct
Leucine aminopeptidase, C-terminal domain0Direct
Creatinase/prolidase N-terminal domain0Direct
Bacterial dinuclear zinc exopeptidases0Direct
Leukotriene A4 hydrolase catalytic domain0Direct
Leukotriene A4 hydrolase C-terminal domain0.000000008693Direct
Sec-C motif0.0008189Direct
beta-Lactamase/D-ala carboxypeptidase0.9298Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Aminopeptidase/glucanase lid domain0Direct
D-aminopeptidase, middle and C-terminal domains0Direct
Creatinase/aminopeptidase0Direct
Zn-dependent exopeptidases0Direct
Creatinase/prolidase N-terminal domain0Direct
Macro domain-like0Direct
Bacterial exopeptidase dimerisation domain0Direct
Leukotriene A4 hydrolase N-terminal domain0Direct
"Winged helix" DNA-binding domain0.00006044Direct
Sec-C motif0.0007242Direct
ARM repeat0.006202Inherited
beta-lactamase/transpeptidase-like0.9367Inherited
alpha/beta-Hydrolases1Inherited
Metalloproteases ("zincins"), catalytic domain1Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
53187,55031
  • 53187 - Zn-dependent exopeptidases
  • 55031 - Bacterial exopeptidase dimerisation domain
  • 0Direct
    101821,53187
  • 101821 - Aminopeptidase/glucanase lid domain
  • 53187 - Zn-dependent exopeptidases
  • 0Direct
    50886,50886
  • 50886 - D-aminopeptidase, middle and C-terminal domains
  • 50886 - D-aminopeptidase, middle and C-terminal domains
  • 0Direct
    56601,50886
  • 56601 - beta-lactamase/transpeptidase-like
  • 50886 - D-aminopeptidase, middle and C-terminal domains
  • 0Direct
    103642,55920
  • 103642 - Sec-C motif
  • 55920 - Creatinase/aminopeptidase
  • 0Direct
    63737,55486
  • 63737 - Leukotriene A4 hydrolase N-terminal domain
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 0Direct
    55920,46785
  • 55920 - Creatinase/aminopeptidase
  • 46785 - "Winged helix" DNA-binding domain
  • 0Direct
    53092,53092
  • 53092 - Creatinase/prolidase N-terminal domain
  • 53092 - Creatinase/prolidase N-terminal domain
  • 0Direct
    53092,55920
  • 53092 - Creatinase/prolidase N-terminal domain
  • 55920 - Creatinase/aminopeptidase
  • 0Direct
    52949,53187
  • 52949 - Macro domain-like
  • 53187 - Zn-dependent exopeptidases
  • 0Direct
    55486,48371
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 48371 - ARM repeat
  • 0.00000000477Direct

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    53092,53092,55920
  • 53092 - Creatinase/prolidase N-terminal domain
  • 53092 - Creatinase/prolidase N-terminal domain
  • 55920 - Creatinase/aminopeptidase
  • 0Direct
    56601,50886,50886
  • 56601 - beta-lactamase/transpeptidase-like
  • 50886 - D-aminopeptidase, middle and C-terminal domains
  • 50886 - D-aminopeptidase, middle and C-terminal domains
  • 0Direct
    63737,55486,48371
  • 63737 - Leukotriene A4 hydrolase N-terminal domain
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 48371 - ARM repeat
  • 0.00000000477Direct


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
    (show help)