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Enzyme Commission (EC): Omega peptidases

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Root: EC Hierarchy (from IntEnz release 70)

Shortest distance to current term (+ for parents, - for children) EC term [EC ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + 3:   root [root] <7>
+ + 2:   Hydrolases [3] <13>(395|668) (394|418|206)
+ 1:   Acting on peptide bonds (peptidases) [3.4] <19>(114|168) (114|130|72)
0:   Omega peptidases [3.4.19] <16>(32|30) (32|24|5)
- 1:   Acylaminoacyl-peptidase [3.4.19.1](3|1) (3|2|0)
- 1:   Beta-aspartyl-peptidase [3.4.19.5](1|1) (1|0|0)
- 1:   Deleted entry [3.4.19.4](0|0) (0|0|0)
- 1:   Desampylase [3.4.19.15](0|0) (0|0|0)
- 1:   Folate gamma-glutamyl hydrolase [3.4.19.9](1|1) (1|0|0)
- 1:   Gamma-D-glutamyl-meso-diaminopimelate peptidase [3.4.19.11](0|0) (0|0|0)
- 1:   Glucosinolate gamma-glutamyl hydrolase [3.4.19.16](1|1) (1|0|0)
- 1:   Glutathione gamma-glutamate hydrolase [3.4.19.13](1|1) (1|0|0)
- 1:   Leukotriene-C(4) hydrolase [3.4.19.14](1|1) (1|0|0)
- 1:   N-formylmethionyl-peptidase [3.4.19.7](0|0) (0|0|0)
- 1:   Peptidyl-glycinamidase [3.4.19.2](0|0) (0|0|0)
- 1:   Pyroglutamyl-peptidase I [3.4.19.3](1|1) (1|0|0)
- 1:   Pyroglutamyl-peptidase II [3.4.19.6](2|1) (2|1|0)
- 1:   Transferred entry: 3.4.17.21 [3.4.19.8](0|0) (0|0|0)
- 1:   Transferred entry: 3.5.1.28 [3.4.19.10](0|0) (0|0|0)
- 1:   Ubiquitinyl hydrolase 1 [3.4.19.12](23|24) (23|21|5)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
UBA-like0Direct
Replicase NSP90Direct
EndoU-like0Direct
Cap-Gly domain0Direct
HIT/MYND zinc finger-like0Direct
SARS Nsp1-like0Direct
Pyrrolidone carboxyl peptidase (pyroglutamate aminopeptidase)0Direct
Cysteine proteinases0Direct
Coronavirus NSP10-like0Direct
Coronavirus NSP7-like0Direct
NSP3A-like0Direct
DUSP-like0Direct
Ubiquitin-like0Direct
RING/U-box0Direct
Coronavirus NSP8-like0Direct
Ran binding protein zinc finger-like0.000000000000002009Direct
JAB1/MPN domain0.0000000004414Direct
Rhodanese/Cell cycle control phosphatase0.000000002425Direct
TRAF domain-like0.000000006238Direct
HSP20-like chaperones0.00000217Direct
ARM repeat0.000002654Direct
Peptidase/esterase 'gauge' domain0.01041Inherited
EF-hand0.02663Inherited
Class I glutamine amidotransferase-like0.1159Inherited
Macro domain-like0.2856Inherited
DNA/RNA polymerases0.92Inherited
Leukotriene A4 hydrolase N-terminal domain0.9909Inherited
DPP6 N-terminal domain-like1Inherited
N-terminal nucleophile aminohydrolases (Ntn hydrolases)1Inherited
Trypsin-like serine proteases1Inherited
Metalloproteases ("zincins"), catalytic domain1Inherited
alpha/beta-Hydrolases1Inherited


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Family

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SCOP termFDR (all)Annotation (direct or inherited)
Zf-UBP0Direct
Coronavirus NSP7-like0Direct
Viral cysteine protease of trypsin fold0Direct
Cap-Gly domain0Direct
Ubiquitin carboxyl-terminal hydrolase UCH-L0Direct
Pyrrolidone carboxyl peptidase (pyroglutamate aminopeptidase)0Direct
SARS Nsp1-like0Direct
Replicase NSP90Direct
NSP3A-like0Direct
(Glycosyl)asparaginase0Direct
Gamma-glutamyltranspeptidase-like0Direct
Ubiquitin thiolesterase protein OTUB2 (Otubain-2)0Direct
UBA domain0Direct
DUSP, domain in ubiquitin-specific proteases0Direct
Nsp15 N-terminal domain-like0Direct
Ubiquitin-related0Direct
Macro domain0Direct
M48USP-like0Direct
Acylamino-acid-releasing enzyme, C-terminal donain0Direct
Nsp15 C-terminal domain-like0Direct
Coronavirus NSP8-like0Direct
Coronavirus NSP10-like0Direct
Ubiquitin carboxyl-terminal hydrolase, UCH0Direct
MYND zinc finger1.854e-16Direct
Ran binding protein zinc finger-like0.000000000000001282Direct
GS domain0.0000000003142Direct
MATH domain0.00000001286Direct
Class I glutamine amidotransferases (GAT)0.03173Inherited
Leukotriene A4 hydrolase catalytic domain0.8875Inherited
Viral proteases1Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Coronavirus NSP7-like0Direct
Ubiquitin-like0Direct
HIT/MYND zinc finger-like0Direct
UBA-like0Direct
NSP3A-like0Direct
Cap-Gly domain0Direct
Replicase NSP90Direct
Cysteine proteinases0Direct
Coronavirus NSP8-like0Direct
DUSP-like0Direct
SARS Nsp1-like0Direct
Pyrrolidone carboxyl peptidase (pyroglutamate aminopeptidase)0Direct
Coronavirus NSP10-like0Direct
EndoU-like0Direct
RING/U-box0Direct
Ran binding protein zinc finger-like0.000000000000001407Direct
JAB1/MPN domain0.0000000003277Direct
Rhodanese/Cell cycle control phosphatase0.000000001817Direct
TRAF domain-like0.000000004704Direct
HSP20-like chaperones0.000001703Direct
ARM repeat0.000002083Direct
Peptidase/esterase 'gauge' domain0.008835Inherited
EF-hand0.02284Inherited
Class I glutamine amidotransferase-like0.1015Inherited
Macro domain-like0.2575Inherited
DNA/RNA polymerases0.8504Inherited
Leukotriene A4 hydrolase N-terminal domain0.9179Inherited
alpha/beta-Hydrolases1Inherited
N-terminal nucleophile aminohydrolases (Ntn hydrolases)1Inherited
Trypsin-like serine proteases1Inherited
Metalloproteases ("zincins"), catalytic domain1Inherited
DPP6 N-terminal domain-like1Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
49599,54001
  • 49599 - TRAF domain-like
  • 54001 - Cysteine proteinases
  • 0Direct
    159936,53335
  • 159936 - NSP3A-like
  • 53335 - S-adenosyl-L-methionine-dependent methyltransferases
  • 0Direct
    54236,54001
  • 54236 - Ubiquitin-like
  • 54001 - Cysteine proteinases
  • 0Direct
    74924,74924
  • 74924 - Cap-Gly domain
  • 74924 - Cap-Gly domain
  • 0Direct
    54001,143791
  • 54001 - Cysteine proteinases
  • 143791 - DUSP-like
  • 0Direct
    54001,55205
  • 54001 - Cysteine proteinases
  • 55205 - EPT/RTPC-like
  • 0Direct
    54001,46934
  • 54001 - Cysteine proteinases
  • 46934 - UBA-like
  • 0Direct
    143791,54236
  • 143791 - DUSP-like
  • 54236 - Ubiquitin-like
  • 0Direct
    57850,54001
  • 57850 - RING/U-box
  • 54001 - Cysteine proteinases
  • 0Direct
    74924,54001
  • 74924 - Cap-Gly domain
  • 54001 - Cysteine proteinases
  • 0Direct
    140367,143076
  • 140367 - Coronavirus NSP7-like
  • 143076 - Coronavirus NSP8-like
  • 0Direct
    53335,142877
  • 53335 - S-adenosyl-L-methionine-dependent methyltransferases
  • 142877 - EndoU-like
  • 0Direct
    54001,144232
  • 54001 - Cysteine proteinases
  • 144232 - HIT/MYND zinc finger-like
  • 0Direct
    101816,144246
  • 101816 - Replicase NSP9
  • 144246 - Coronavirus NSP10-like
  • 0Direct
    143791,143791
  • 143791 - DUSP-like
  • 143791 - DUSP-like
  • 0Direct
    143076,101816
  • 143076 - Coronavirus NSP8-like
  • 101816 - Replicase NSP9
  • 0Direct
    159936,52949
  • 159936 - NSP3A-like
  • 52949 - Macro domain-like
  • 0Direct
    48371,54001
  • 48371 - ARM repeat
  • 54001 - Cysteine proteinases
  • 0Direct
    52540,142877
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 142877 - EndoU-like
  • 7.06e-16Direct
    90209,90209
  • 90209 - Ran binding protein zinc finger-like
  • 90209 - Ran binding protein zinc finger-like
  • 0.0000000003277Direct
    56672,52540
  • 56672 - DNA/RNA polymerases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.000000004759Direct
    50993,53474
  • 50993 - Peptidase/esterase 'gauge' domain
  • 53474 - alpha/beta-Hydrolases
  • 0.008835Inherited
    63737,55486
  • 63737 - Leukotriene A4 hydrolase N-terminal domain
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 0.9179Inherited
    82171,53474
  • 82171 - DPP6 N-terminal domain-like
  • 53474 - alpha/beta-Hydrolases
  • 1Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    54001,143791,143791
  • 54001 - Cysteine proteinases
  • 143791 - DUSP-like
  • 143791 - DUSP-like
  • 0Direct
    143076,101816,144246
  • 143076 - Coronavirus NSP8-like
  • 101816 - Replicase NSP9
  • 144246 - Coronavirus NSP10-like
  • 0Direct
    140367,143076,101816
  • 140367 - Coronavirus NSP7-like
  • 143076 - Coronavirus NSP8-like
  • 101816 - Replicase NSP9
  • 0Direct
    52540,52540,142877
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 142877 - EndoU-like
  • 0.0000000003277Direct
    56672,52540,52540
  • 56672 - DNA/RNA polymerases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.000000001609Direct


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
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