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Enzyme Commission (EC): Aspartic endopeptidases

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Root: EC Hierarchy (from IntEnz release 70)

Shortest distance to current term (+ for parents, - for children) EC term [EC ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + 3:   root [root] <7>
+ + 2:   Hydrolases [3] <13>(395|668) (394|417|206)
+ 1:   Acting on peptide bonds (peptidases) [3.4] <19>(114|168) (114|129|72)
0:   Aspartic endopeptidases [3.4.23] <52>(11|13) (11|9|8)
- 1:   3.4.23.28 and 3.4.23.30 [3.4.23.6](0|0) (0|0|0)
- 1:   Acrocylindropepsin [3.4.23.28](0|0) (0|0|0)
- 1:   Aspergillopepsin I [3.4.23.18](0|0) (0|0|0)
- 1:   Aspergillopepsin II [3.4.23.19](0|0) (0|0|0)
- 1:   Barrierpepsin [3.4.23.35](0|0) (0|0|0)
- 1:   Candidapepsin [3.4.23.24](0|0) (0|0|0)
- 1:   Cathepsin D [3.4.23.5](0|0) (0|0|0)
- 1:   Cathepsin E [3.4.23.34](0|0) (0|0|0)
- 1:   Chymosin [3.4.23.4](0|0) (0|0|0)
- 1:   Deleted entry [3.4.23.11](0|0) (0|0|0)
- 1:   Deleted entry [3.4.23.13](0|0) (0|0|0)
- 1:   Deleted entry [3.4.23.14](0|0) (0|0|0)
- 1:   Endothiapepsin [3.4.23.22](0|0) (0|0|0)
- 1:   Gastricsin [3.4.23.3](0|0) (0|0|0)
- 1:   HIV-1 retropepsin [3.4.23.16](8|10) (8|9|8)
- 1:   HIV-2 retropepsin [3.4.23.47](8|10) (8|9|8)
- 1:   Human endogenous retrovirus K endopeptidase [3.4.23.50](0|1) (0|0|0)
- 1:   HycI peptidase [3.4.23.51](0|0) (0|0|0)
- 1:   Memapsin 1 [3.4.23.45](0|0) (0|0|0)
- 1:   Memapsin 2 [3.4.23.46](0|0) (0|0|0)
- 1:   Mucorpepsin [3.4.23.23](0|0) (0|0|0)
- 1:   Nepenthesin [3.4.23.12](0|0) (0|0|0)
- 1:   Nodavirus endopeptidase [3.4.23.44](1|1) (1|0|0)
- 1:   Omptin [3.4.23.49](0|0) (0|0|0)
- 1:   Penicillopepsin [3.4.23.20](0|0) (0|0|0)
- 1:   Pepsin A [3.4.23.1](0|0) (0|0|0)
- 1:   Pepsin B [3.4.23.2](0|0) (0|0|0)
- 1:   Phytepsin [3.4.23.40](0|0) (0|0|0)
- 1:   Plasmepsin I [3.4.23.38](0|0) (0|0|0)
- 1:   Plasmepsin II [3.4.23.39](0|0) (0|0|0)
- 1:   Plasminogen activator Pla [3.4.23.48](0|0) (0|0|0)
- 1:   Polyporopepsin [3.4.23.29](0|0) (0|0|0)
- 1:   Preflagellin peptidase [3.4.23.52](0|0) (0|0|0)
- 1:   Prepilin peptidase [3.4.23.43](0|0) (0|0|0)
- 1:   Pro-opiomelanocortin converting enzyme [3.4.23.17](0|0) (0|0|0)
- 1:   Pycnoporopepsin [3.4.23.30](0|0) (0|0|0)
- 1:   Renin [3.4.23.15](0|0) (0|0|0)
- 1:   Rhizopuspepsin [3.4.23.21](0|0) (0|0|0)
- 1:   Rhodotorulapepsin [3.4.23.26](0|0) (0|0|0)
- 1:   Saccharopepsin [3.4.23.25](0|0) (0|0|0)
- 1:   Scytalidopepsin A [3.4.23.31](0|0) (0|0|0)
- 1:   Scytalidopepsin B [3.4.23.32](0|0) (0|0|0)
- 1:   Signal peptidase II [3.4.23.36](0|0) (0|0|0)
- 1:   Thermopsin [3.4.23.42](0|0) (0|0|0)
- 1:   Transferred entry: 3.4.21.100 [3.4.23.37](0|0) (0|0|0)
- 1:   Transferred entry: 3.4.21.101 [3.4.23.33](0|0) (0|0|0)
- 1:   Transferred entry: 3.4.21.103 [3.4.23.27](0|0) (0|0|0)
- 1:   Transferred entry: 3.4.23.20 [3.4.23.7](0|0) (0|0|0)
- 1:   Transferred entry: 3.4.23.21 [3.4.23.9](0|0) (0|0|0)
- 1:   Transferred entry: 3.4.23.22 [3.4.23.10](0|0) (0|0|0)
- 1:   Transferred entry: 3.4.23.25 [3.4.23.8](0|0) (0|0|0)
- 1:   Yapsin 1 [3.4.23.41](0|0) (0|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
Acid proteases0Direct
Retrovirus zinc finger-like domains0Direct
OMPT-like0Direct
Retrovirus capsid dimerization domain-like0Direct
Retroviral matrix proteins0Direct
Retrovirus capsid protein, N-terminal core domain0Direct
DNA-binding domain of retroviral integrase0Direct
Ribonuclease H-like0Direct
DNA/RNA polymerases0Direct
N-terminal Zn binding domain of HIV integrase0Direct
Positive stranded ssRNA viruses0.2154Inherited


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Family

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SCOP termFDR (all)Annotation (direct or inherited)
Retroviral protease (retropepsin)0Direct
Nodaviridae-like VP0Direct
Retroviral integrase, catalytic domain0Direct
N-terminal Zn binding domain of HIV integrase0Direct
Ribonuclease H0Direct
Pepsin-like0Direct
Retrovirus zinc finger-like domains0Direct
Retrovirus capsid protein, N-terminal core domain0Direct
Outer membrane protease OMPT0Direct
Reverse transcriptase0Direct
Retrovirus capsid protein C-terminal domain0Direct
Immunodeficiency virus matrix proteins0Direct
DNA-binding domain of retroviral integrase0Direct


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

(show details)
Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Retrovirus capsid dimerization domain-like0Direct
Ribonuclease H-like0Direct
OMPT-like0Direct
Acid proteases0Direct
N-terminal Zn binding domain of HIV integrase0Direct
Retrovirus capsid protein, N-terminal core domain0Direct
Retroviral matrix proteins0Direct
DNA-binding domain of retroviral integrase0Direct
DNA/RNA polymerases0Direct
Retrovirus zinc finger-like domains0Direct
Positive stranded ssRNA viruses0.1915Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
47836,47943
  • 47836 - Retroviral matrix proteins
  • 47943 - Retrovirus capsid protein, N-terminal core domain
  • 0Direct
    53098,46919
  • 53098 - Ribonuclease H-like
  • 46919 - N-terminal Zn binding domain of HIV integrase
  • 0Direct
    50630,56672
  • 50630 - Acid proteases
  • 56672 - DNA/RNA polymerases
  • 0Direct
    56672,53098
  • 56672 - DNA/RNA polymerases
  • 53098 - Ribonuclease H-like
  • 0Direct
    53098,50122
  • 53098 - Ribonuclease H-like
  • 50122 - DNA-binding domain of retroviral integrase
  • 0Direct
    46919,53098
  • 46919 - N-terminal Zn binding domain of HIV integrase
  • 53098 - Ribonuclease H-like
  • 0Direct
    47943,47353
  • 47943 - Retrovirus capsid protein, N-terminal core domain
  • 47353 - Retrovirus capsid dimerization domain-like
  • 0Direct
    57756,50630
  • 57756 - Retrovirus zinc finger-like domains
  • 50630 - Acid proteases
  • 0Direct
    47353,57756
  • 47353 - Retrovirus capsid dimerization domain-like
  • 57756 - Retrovirus zinc finger-like domains
  • 0Direct

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    47353,57756,50630
  • 47353 - Retrovirus capsid dimerization domain-like
  • 57756 - Retrovirus zinc finger-like domains
  • 50630 - Acid proteases
  • 0Direct
    50630,56672,53098
  • 50630 - Acid proteases
  • 56672 - DNA/RNA polymerases
  • 53098 - Ribonuclease H-like
  • 0Direct
    47943,47353,57756
  • 47943 - Retrovirus capsid protein, N-terminal core domain
  • 47353 - Retrovirus capsid dimerization domain-like
  • 57756 - Retrovirus zinc finger-like domains
  • 0Direct
    57756,50630,56672
  • 57756 - Retrovirus zinc finger-like domains
  • 50630 - Acid proteases
  • 56672 - DNA/RNA polymerases
  • 0Direct
    46919,53098,50122
  • 46919 - N-terminal Zn binding domain of HIV integrase
  • 53098 - Ribonuclease H-like
  • 50122 - DNA-binding domain of retroviral integrase
  • 0Direct
    47836,47943,47353
  • 47836 - Retroviral matrix proteins
  • 47943 - Retrovirus capsid protein, N-terminal core domain
  • 47353 - Retrovirus capsid dimerization domain-like
  • 0Direct
    56672,53098,46919
  • 56672 - DNA/RNA polymerases
  • 53098 - Ribonuclease H-like
  • 46919 - N-terminal Zn binding domain of HIV integrase
  • 0Direct
    53098,46919,53098
  • 53098 - Ribonuclease H-like
  • 46919 - N-terminal Zn binding domain of HIV integrase
  • 53098 - Ribonuclease H-like
  • 0Direct


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
    (show help)