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Enzyme Commission (EC): In linear amides

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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Root: EC Hierarchy (from IntEnz release 70)

Shortest distance to current term (+ for parents, - for children) EC term [EC ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + 3:   root [root] <7>
+ + 2:   Hydrolases [3] <13>(395|668) (394|417|206)
+ 1:   Acting on carbon-nitrogen bonds, other than peptide bonds [3.5] <6>(72|104) (72|40|18)
0:   In linear amides [3.5.1] <135>(38|49) (38|20|7)
- 1:   (R)-amidase [3.5.1.100](0|0) (0|0|0)
- 1:   (S)-N-acetyl-1-phenylethylamine hydrolase [3.5.1.85](0|0) (0|0|0)
- 1:   1-carboxybiuret hydrolase [3.5.1.131](0|0) (0|0|0)
- 1:   2'''-acetyl-6'''-hydroxyneomycin C deacetylase [3.5.1.113](0|0) (0|0|0)
- 1:   2'-N-acetylparomamine deacetylase [3.5.1.112](0|0) (0|0|0)
- 1:   2-(acetamidomethylene)succinate hydrolase [3.5.1.29](0|0) (0|0|0)
- 1:   2-(hydroxymethyl)-3-(acetamidomethylene)succinate hydrolase [3.5.1.66](0|0) (0|0|0)
- 1:   2-oxoglutaramate amidase [3.5.1.111](0|0) (0|0|0)
- 1:   4-acetamidobutyrate deacetylase [3.5.1.63](0|0) (0|0|0)
- 1:   4-acetamidobutyryl-CoA deacetylase [3.5.1.51](0|0) (0|0|0)
- 1:   4-deoxy-4-formamido-L-arabinose-phosphoundecaprenol deformylase [3.5.1.n3](1|0) (1|0|0)
- 1:   4-methyleneglutaminase [3.5.1.67](0|0) (0|0|0)
- 1:   5-aminopentanamidase [3.5.1.30](0|0) (0|0|0)
- 1:   6-aminohexanoate-oligomer endohydrolase [3.5.1.117](0|0) (0|0|0)
- 1:   6-aminohexanoate-oligomer exohydrolase [3.5.1.46](0|0) (0|0|0)
- 1:   Acetylornithine deacetylase [3.5.1.16](2|2) (2|1|0)
- 1:   Acetylputrescine deacetylase [3.5.1.62](1|1) (1|1|0)
- 1:   Acetylspermidine deacetylase [3.5.1.48](1|1) (1|1|0)
- 1:   Aculeacin-A deacylase [3.5.1.70](0|0) (0|0|0)
- 1:   Acyl-homoserine-lactone acylase [3.5.1.97](1|1) (1|0|0)
- 1:   Acyl-lysine deacylase [3.5.1.17](0|0) (0|0|0)
- 1:   Acylagmatine amidase [3.5.1.40](0|0) (0|0|0)
- 1:   Adenosylcobinamide hydrolase [3.5.1.90](0|0) (0|0|0)
- 1:   Alkylamidase [3.5.1.39](0|0) (0|0|0)
- 1:   Allophanate hydrolase [3.5.1.54](1|1) (1|0|0)
- 1:   Amidase [3.5.1.4](2|2) (2|0|0)
- 1:   Aryl-acylamidase [3.5.1.13](0|0) (0|0|0)
- 1:   Arylalkyl acylamidase [3.5.1.76](0|0) (0|0|0)
- 1:   Arylformamidase [3.5.1.9](2|3) (2|0|0)
- 1:   Asparaginase [3.5.1.1](3|3) (3|1|0)
- 1:   Aspartoacylase [3.5.1.15](1|1) (1|0|0)
- 1:   Beta-ureidopropionase [3.5.1.6](1|1) (1|0|0)
- 1:   Biotinidase [3.5.1.12](1|0) (1|0|0)
- 1:   Biuret amidohydrolase [3.5.1.84](0|0) (0|0|0)
- 1:   Carnitinamidase [3.5.1.73](0|0) (0|0|0)
- 1:   Ceramidase [3.5.1.23](0|0) (0|0|0)
- 1:   Chenodeoxycholoyltaurine hydrolase [3.5.1.74](0|0) (0|0|0)
- 1:   Chitin deacetylase [3.5.1.41](1|1) (1|0|0)
- 1:   Chitin disaccharide deacetylase [3.5.1.105](1|1) (1|0|0)
- 1:   Choloylglycine hydrolase [3.5.1.24](0|0) (0|0|0)
- 1:   Citrullinase [3.5.1.20](0|0) (0|0|0)
- 1:   D-benzoylarginine-4-nitroanilide amidase [3.5.1.72](0|0) (0|0|0)
- 1:   D-glutaminase [3.5.1.35](0|0) (0|0|0)
- 1:   Deaminated glutathione amidase [3.5.1.128](1|1) (1|0|0)
- 1:   Deleted entry [3.5.1.27](0|0) (0|0|0)
- 1:   Fatty acid amide hydrolase [3.5.1.99](1|1) (1|0|0)
- 1:   Formamidase [3.5.1.49](1|1) (1|0|0)
- 1:   Formylaspartate deformylase [3.5.1.8](0|0) (0|0|0)
- 1:   Formylmethionine deformylase [3.5.1.31](0|0) (0|0|0)
- 1:   Formyltetrahydrofolate deformylase [3.5.1.10](2|1) (2|1|0)
- 1:   Gamma-glutamyl hercynylcysteine S-oxide hydrolase [3.5.1.118](1|1) (1|0|0)
- 1:   Gamma-glutamyl-gamma-aminobutyrate hydrolase [3.5.1.94](0|0) (0|0|0)
- 1:   Gamma-glutamylanilide hydrolase [3.5.1.123](0|0) (0|0|0)
- 1:   Glutamin-(asparagin-)ase [3.5.1.38](1|1) (1|0|0)
- 1:   Glutaminase [3.5.1.2](4|3) (4|3|0)
- 1:   Glutaryl-7-aminocephalosporanic-acid acylase [3.5.1.93](1|0) (1|0|0)
- 1:   Glutathionylspermidine amidase [3.5.1.78](0|0) (0|0|0)
- 1:   Glycosphingolipid deacylase [3.5.1.69](0|0) (0|0|0)
- 1:   Hippurate hydrolase [3.5.1.32](0|0) (0|0|0)
- 1:   Histone deacetylase [3.5.1.98](1|2) (1|0|0)
- 1:   Jasmonoyl-L-amino acid hydrolase [3.5.1.127](0|0) (0|0|0)
- 1:   L-proline amide hydrolase [3.5.1.101](0|0) (0|0|0)
- 1:   Long-chain-fatty-acyl-glutamate deacylase [3.5.1.55](0|0) (0|0|0)
- 1:   Maleamate amidohydrolase [3.5.1.107](0|0) (0|0|0)
- 1:   Mandelamide amidase [3.5.1.86](0|0) (0|0|0)
- 1:   Mimosinase [3.5.1.61](0|0) (0|0|0)
- 1:   Mycothiol S-conjugate amidase [3.5.1.115](1|1) (1|0|0)
- 1:   N(2)-acetyl-L-2,4-diaminobutanoate deacetylase [3.5.1.125](0|0) (0|0|0)
- 1:   N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase [3.5.1.26](1|1) (1|0|0)
- 1:   N(5)-(cytidine 5'-diphosphoramidyl)-L-glutamine hydrolase [3.5.1.129](0|0) (0|0|0)
- 1:   N(alpha)-benzyloxycarbonylleucine hydrolase [3.5.1.64](0|0) (0|0|0)
- 1:   N,N-dimethylformamidase [3.5.1.56](0|0) (0|0|0)
- 1:   N-(long-chain-acyl)ethanolamine deacylase [3.5.1.60](0|0) (0|0|0)
- 1:   N-acetyl-beta-alanine deacetylase [3.5.1.21](0|0) (0|0|0)
- 1:   N-acetyldiaminopimelate deacetylase [3.5.1.47](2|2) (2|1|0)
- 1:   N-acetylglucosamine deacetylase [3.5.1.33](0|0) (0|0|0)
- 1:   N-acetylglucosamine-6-phosphate deacetylase [3.5.1.25](2|2) (2|1|0)
- 1:   N-acetylglucosaminylphosphatidylinositol deacetylase [3.5.1.89](1|1) (1|0|0)
- 1:   N-acetylmuramoyl-L-alanine amidase [3.5.1.28](6|6) (6|4|2)
- 1:   N-acyl-D-amino-acid deacylase [3.5.1.81](0|0) (0|0|0)
- 1:   N-acyl-D-aspartate deacylase [3.5.1.83](0|0) (0|0|0)
- 1:   N-acyl-D-glutamate deacylase [3.5.1.82](0|0) (0|0|0)
- 1:   N-acyl-aliphatic-L-amino acid amidohydrolase [3.5.1.14](2|2) (2|1|0)
- 1:   N-acyl-aromatic-L-amino acid amidohydrolase [3.5.1.114](1|1) (1|0|0)
- 1:   N-benzyloxycarbonylglycine hydrolase [3.5.1.58](0|0) (0|0|0)
- 1:   N-carbamoyl-D-amino-acid hydrolase [3.5.1.77](1|1) (1|0|0)
- 1:   N-carbamoyl-L-amino-acid hydrolase [3.5.1.87](2|2) (2|1|0)
- 1:   N-carbamoylputrescine amidase [3.5.1.53](1|1) (1|0|0)
- 1:   N-carbamoylsarcosine amidase [3.5.1.59](0|0) (0|0|0)
- 1:   N-feruloylglycine deacylase [3.5.1.71](0|0) (0|0|0)
- 1:   N-formylglutamate deformylase [3.5.1.68](0|0) (0|0|0)
- 1:   N-formylmaleamate deformylase [3.5.1.106](0|0) (0|0|0)
- 1:   N-malonylurea hydrolase [3.5.1.95](0|0) (0|0|0)
- 1:   N-methyl-2-oxoglutaramate hydrolase [3.5.1.36](0|0) (0|0|0)
- 1:   N-substituted formamide deformylase [3.5.1.91](0|0) (0|0|0)
- 1:   Nicotinamidase [3.5.1.19](1|1) (1|0|0)
- 1:   Nicotinamide-nucleotide amidase [3.5.1.42](1|1) (1|0|0)
- 1:   Omega-amidase [3.5.1.3](1|1) (1|0|0)
- 1:   Oxamate amidohydrolase [3.5.1.126](0|0) (0|0|0)
- 1:   Pantetheine hydrolase [3.5.1.92](1|1) (1|0|0)
- 1:   Pantothenase [3.5.1.22](0|0) (0|0|0)
- 1:   Penicillin amidase [3.5.1.11](1|1) (1|0|0)
- 1:   Pentanamidase [3.5.1.50](0|0) (0|0|0)
- 1:   Peptide deformylase [3.5.1.88](1|1) (1|0|0)
- 1:   Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase [3.5.1.52](3|3) (3|2|1)
- 1:   Peptidoglycan-N-acetylglucosamine deacetylase [3.5.1.104](1|1) (1|0|0)
- 1:   Peptidyl-glutaminase [3.5.1.43](0|0) (0|0|0)
- 1:   Peroxyureidoacrylate/ureidoacrylate amidohydrolase [3.5.1.110](1|1) (1|0|0)
- 1:   Phthalyl amidase [3.5.1.79](0|0) (0|0|0)
- 1:   Protein N-terminal asparagine amidohydrolase [3.5.1.121](0|0) (0|0|0)
- 1:   Protein N-terminal glutamine amidohydrolase [3.5.1.122](0|0) (0|0|0)
- 1:   Protein deglycase [3.5.1.124](1|1) (1|0|0)
- 1:   Protein-glutamine glutaminase [3.5.1.44](3|3) (3|1|0)
- 1:   Pup amidohydrolase [3.5.1.119](0|0) (0|0|0)
- 1:   Sphingomyelin deacylase [3.5.1.109](0|0) (0|0|0)
- 1:   Succinyl-diaminopimelate desuccinylase [3.5.1.18](2|2) (2|1|0)
- 1:   Succinylglutamate desuccinylase [3.5.1.96](1|1) (1|0|0)
- 1:   Theanine hydrolase [3.5.1.65](0|0) (0|0|0)
- 1:   Transferred entry: 3.4.13.5 [3.5.1.34](0|0) (0|0|0)
- 1:   Transferred entry: 3.5.1.108 [3.5.1.n1](0|0) (0|0|0)
- 1:   Transferred entry: 3.5.1.110 [3.5.1.n4](0|0) (0|0|0)
- 1:   Transferred entry: 3.5.1.25 [3.5.1.80](0|0) (0|0|0)
- 1:   Transferred entry: 3.5.1.26 [3.5.1.37](0|0) (0|0|0)
- 1:   Transferred entry: 3.5.1.99 [3.5.1.n2](0|0) (0|0|0)
- 1:   Transferred entry: 3.5.99.11 [3.5.1.120](0|0) (0|0|0)
- 1:   Transferred entry: 6.3.4.6 [3.5.1.45](0|0) (0|0|0)
- 1:   Tryptophanamidase [3.5.1.57](0|0) (0|0|0)
- 1:   UDP-3-O-acyl-N-acetylglucosamine deacetylase [3.5.1.108](1|1) (1|2|1)
- 1:   Urease [3.5.1.5](4|4) (4|4|3)
- 1:   Ureidoglycolate amidohydrolase [3.5.1.116](0|0) (0|0|0)
- 1:   Ureidosuccinase [3.5.1.7](0|0) (0|0|0)
- 1:   Urethanase [3.5.1.75](0|0) (0|0|0)
- 1:   [Lysine-biosynthesis-protein LysW]-lysine/ornithine hydrolase [3.5.1.130](0|0) (0|0|0)
- 1:   deacetylase [3.5.1.103](1|1) (1|0|0)
- 1:   deformylase [3.5.1.102](1|1) (1|0|0)


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Superfamily

(show details)
SCOP termFDR (all)Annotation (direct or inherited)
Putative cyclase0Direct
Glutaminase/Asparaginase0Direct
Prokaryotic SH3-related domain0Direct
Methylesterase CheB, C-terminal domain0Direct
N-acetylmuramoyl-L-alanine amidase-like0Direct
CNF1/YfiH-like putative cysteine hydrolases0Direct
LmbE-like0Direct
CheY-like0Direct
Peptide deformylase0Direct
Acetamidase/Formamidase-like0Direct
Isochorismatase-like hydrolases0Direct
Class I glutamine amidotransferase-like0Direct
Zn-dependent exopeptidases0Direct
SpoIIaa-like0Direct
Urease, gamma-subunit0Direct
Ribosomal protein S5 domain 2-like0Direct
CinA-like0Direct
Urease, beta-subunit0Direct
Bacterial exopeptidase dimerisation domain0Direct
LysM domain0.000000000000001014Direct
PUG domain-like0.00000000000001433Direct
Carbon-nitrogen hydrolase0.0000000000006295Direct
N-terminal nucleophile aminohydrolases (Ntn hydrolases)0.0000000001351Direct
Amidase signature (AS) enzymes0.000000006648Direct
beta-lactamase/transpeptidase-like0.00000002305Direct
Creatininase0.0000004677Direct
PGBD-like0.000001089Direct
Ankyrin repeat0.00003298Direct
Cysteine proteinases0.00004969Direct
Cell wall binding repeat0.0001694Direct
ACT-like0.3434Inherited
Formyltransferase1Inherited
alpha/beta-Hydrolases1Inherited
Glycoside hydrolase/deacetylase1Inherited
Arginase/deacetylase1Inherited
Composite domain of metallo-dependent hydrolases1Inherited
Galactose-binding domain-like1Inherited
Metallo-dependent hydrolases1Inherited


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Family

(show details)
SCOP termFDR (all)Annotation (direct or inherited)
UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase LpxC0Direct
LmbE-like0Direct
Methylesterase CheB, C-terminal domain0Direct
N-acetylglucosamine-6-phosphate deacetylase, NagA0Direct
Glutaminase0Direct
NodB-like polysaccharide deacetylase0Direct
GW domain0Direct
Penicillin acylase, catalytic domain0Direct
AstE/AspA-like0Direct
N-acetylmuramoyl-L-alanine amidase-like0Direct
Glutaminase/Asparaginase0Direct
alpha-Subunit of urease0Direct
YdjC-like0Direct
Histone deacetylase, HDAC0Direct
Bacterial exopeptidase dimerisation domain0Direct
alpha-subunit of urease, catalytic domain0Direct
Nitrilase0Direct
Peptide deformylase0Direct
Isochorismatase-like hydrolases0Direct
Class I glutamine amidotransferases (GAT)0Direct
N-acetylglucosamine-6-phosphate deacetylase, NagA, catalytic domain0Direct
DJ-1/PfpI0Direct
Urease, beta-subunit0Direct
N-acetylmuramoyl-L-alanine amidase-like0Direct
CinA-like0Direct
Extended PAW domain0Direct
Putative cyclase0Direct
CheD-like0Direct
Putative serine hydrolase Ydr428c0Direct
Bacterial dinuclear zinc exopeptidases0Direct
Acetamidase/Formamidase-like0Direct
Transglutaminase core0Direct
D-aminoacylase, catalytic domain0Direct
CheY-related0Direct
(Glycosyl)asparaginase0Direct
D-aminoacylase0Direct
Urease, gamma-subunit0Direct
LysM domain0.000000000000001464Direct
PUG domain0.00000000000001691Direct
Peptidoglycan binding domain, PGBD0.00000000000001691Direct
Amidase signature (AS) enzymes0.00000001997Direct
Creatininase0.000004489Direct
Carbamilase0.00003878Direct
Ankyrin repeat0.00004009Direct
Cell wall binding repeat0.0001708Direct
Carboxylesterase0.001487Inherited
Zf-UBP0.03891Inherited
Class II glutamine amidotransferases0.8878Inherited
Formyltransferase0.9936Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

(show details)
Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Putative cyclase0Direct
Prokaryotic SH3-related domain0Direct
CinA-like0Direct
SpoIIaa-like0Direct
Ribosomal protein S5 domain 2-like0Direct
LmbE-like0Direct
Acetamidase/Formamidase-like0Direct
Zn-dependent exopeptidases0Direct
CheY-like0Direct
Class I glutamine amidotransferase-like0Direct
Bacterial exopeptidase dimerisation domain0Direct
Isochorismatase-like hydrolases0Direct
Peptide deformylase0Direct
CNF1/YfiH-like putative cysteine hydrolases0Direct
N-acetylmuramoyl-L-alanine amidase-like0Direct
Urease, gamma-subunit0Direct
Urease, beta-subunit0Direct
Methylesterase CheB, C-terminal domain0Direct
Glutaminase/Asparaginase0Direct
LysM domain7.066e-16Direct
PUG domain-like0.0000000000000101Direct
Carbon-nitrogen hydrolase0.0000000000004511Direct
N-terminal nucleophile aminohydrolases (Ntn hydrolases)0.00000000009957Direct
Amidase signature (AS) enzymes0.000000005015Direct
beta-lactamase/transpeptidase-like0.00000001749Direct
Creatininase0.0000003626Direct
PGBD-like0.0000008499Direct
Ankyrin repeat0.00002638Direct
Cysteine proteinases0.00003987Direct
Cell wall binding repeat0.0001376Direct
ACT-like0.3105Inherited
Formyltransferase0.9464Inherited
Glycoside hydrolase/deacetylase1Inherited
Arginase/deacetylase1Inherited
Composite domain of metallo-dependent hydrolases1Inherited
Galactose-binding domain-like1Inherited
alpha/beta-Hydrolases1Inherited
Metallo-dependent hydrolases1Inherited

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
54111,51278
  • 54111 - Urease, gamma-subunit
  • 51278 - Urease, beta-subunit
  • 0Direct
    53187,55031
  • 53187 - Zn-dependent exopeptidases
  • 55031 - Bacterial exopeptidase dimerisation domain
  • 0Direct
    54211,54637
  • 54211 - Ribosomal protein S5 domain 2-like
  • 54637 - Thioesterase/thiol ester dehydrase-isomerase
  • 0Direct
    54211,54211
  • 54211 - Ribosomal protein S5 domain 2-like
  • 54211 - Ribosomal protein S5 domain 2-like
  • 0Direct
    55846,47090
  • 55846 - N-acetylmuramoyl-L-alanine amidase-like
  • 47090 - PGBD-like
  • 0Direct
    143503,54001
  • 143503 - PUG domain-like
  • 54001 - Cysteine proteinases
  • 0Direct
    55021,53328
  • 55021 - ACT-like
  • 53328 - Formyltransferase
  • 0Direct
    56601,52091
  • 56601 - beta-lactamase/transpeptidase-like
  • 52091 - SpoIIaa-like
  • 0Direct
    51278,51338
  • 51278 - Urease, beta-subunit
  • 51338 - Composite domain of metallo-dependent hydrolases
  • 0Direct
    52768,52768
  • 52768 - Arginase/deacetylase
  • 52768 - Arginase/deacetylase
  • 0Direct
    53774,48403
  • 53774 - Glutaminase/Asparaginase
  • 48403 - Ankyrin repeat
  • 0Direct
    56601,48403
  • 56601 - beta-lactamase/transpeptidase-like
  • 48403 - Ankyrin repeat
  • 0Direct
    54001,49785
  • 54001 - Cysteine proteinases
  • 49785 - Galactose-binding domain-like
  • 0Direct
    52172,52738
  • 52172 - CheY-like
  • 52738 - Methylesterase CheB, C-terminal domain
  • 0Direct
    54106,54001
  • 54106 - LysM domain
  • 54001 - Cysteine proteinases
  • 0.000000000000001058Direct
    54106,54106
  • 54106 - LysM domain
  • 54106 - LysM domain
  • 0.0000000009421Direct
    47090,47090
  • 47090 - PGBD-like
  • 47090 - PGBD-like
  • 0.0000002414Direct
    52317,51366
  • 52317 - Class I glutamine amidotransferase-like
  • 51366 - Ribulose-phoshate binding barrel
  • 0.00003205Direct
    51338,51556
  • 51338 - Composite domain of metallo-dependent hydrolases
  • 51556 - Metallo-dependent hydrolases
  • 1Inherited
    51556,51338
  • 51556 - Metallo-dependent hydrolases
  • 51338 - Composite domain of metallo-dependent hydrolases
  • 1Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    54211,54211,54637
  • 54211 - Ribosomal protein S5 domain 2-like
  • 54211 - Ribosomal protein S5 domain 2-like
  • 54637 - Thioesterase/thiol ester dehydrase-isomerase
  • 0Direct
    54111,51278,51338
  • 54111 - Urease, gamma-subunit
  • 51278 - Urease, beta-subunit
  • 51338 - Composite domain of metallo-dependent hydrolases
  • 0Direct
    51278,51338,51556
  • 51278 - Urease, beta-subunit
  • 51338 - Composite domain of metallo-dependent hydrolases
  • 51556 - Metallo-dependent hydrolases
  • 0Direct
    143503,54001,49785
  • 143503 - PUG domain-like
  • 54001 - Cysteine proteinases
  • 49785 - Galactose-binding domain-like
  • 0Direct
    51338,51556,51338
  • 51338 - Composite domain of metallo-dependent hydrolases
  • 51556 - Metallo-dependent hydrolases
  • 51338 - Composite domain of metallo-dependent hydrolases
  • 0Direct
    54106,54106,54001
  • 54106 - LysM domain
  • 54106 - LysM domain
  • 54001 - Cysteine proteinases
  • 0.00000000000004942Direct
    54106,54106,54106
  • 54106 - LysM domain
  • 54106 - LysM domain
  • 54106 - LysM domain
  • 0.000000000685Direct


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
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