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Enzyme Commission (EC): In cyclic amides

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Root: EC Hierarchy (from IntEnz release 70)

Shortest distance to current term (+ for parents, - for children) EC term [EC ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + 3:   root [root] <7>
+ + 2:   Hydrolases [3] <13>(395|668) (394|417|206)
+ 1:   Acting on carbon-nitrogen bonds, other than peptide bonds [3.5] <6>(72|104) (72|40|18)
0:   In cyclic amides [3.5.2] <20>(14|16) (14|10|9)
- 1:   2,5-dioxopiperazine hydrolase [3.5.2.13](0|0) (0|0|0)
- 1:   5-oxoprolinase (ATP-hydrolyzing) [3.5.2.9](3|2) (3|1|0)
- 1:   6-aminohexanoate-cyclic-dimer hydrolase [3.5.2.12](0|0) (0|0|0)
- 1:   Allantoinase [3.5.2.5](1|1) (1|1|0)
- 1:   Barbiturase [3.5.2.1](0|0) (0|0|0)
- 1:   Beta-lactamase [3.5.2.6](3|3) (3|0|0)
- 1:   Carboxymethylhydantoinase [3.5.2.4](0|0) (0|0|0)
- 1:   Creatininase [3.5.2.10](0|0) (0|0|0)
- 1:   Cyanuric acid amidohydrolase [3.5.2.15](0|0) (0|0|0)
- 1:   Dihydroorotase [3.5.2.3](6|8) (6|8|8)
- 1:   Dihydropyrimidinase [3.5.2.2](0|2) (0|1|1)
- 1:   Enamidase [3.5.2.18](0|0) (0|0|0)
- 1:   Hydroxyisourate hydrolase [3.5.2.17](1|1) (1|0|0)
- 1:   Imidazolonepropionase [3.5.2.7](2|2) (2|1|0)
- 1:   Isatin hydrolase [3.5.2.20](0|0) (0|0|0)
- 1:   L-lysine-lactamase [3.5.2.11](0|0) (0|0|0)
- 1:   Maleimide hydrolase [3.5.2.16](0|0) (0|0|0)
- 1:   N-methylhydantoinase (ATP-hydrolyzing) [3.5.2.14](0|0) (0|0|0)
- 1:   Streptothricin hydrolase [3.5.2.19](0|0) (0|0|0)
- 1:   Transferred entry: 3.5.2.6 [3.5.2.8](0|0) (0|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
Glycoside hydrolase/deacetylase0Direct
beta-lactamase/transpeptidase-like0Direct
Transthyretin (synonym: prealbumin)0Direct
Composite domain of metallo-dependent hydrolases0Direct
HCP-like0Direct
Metallo-dependent hydrolases0Direct
Metallo-hydrolase/oxidoreductase0.000000001889Direct
Carbamoyl phosphate synthetase, small subunit N-terminal domain0.00001223Direct
Carbamoyl phosphate synthetase, large subunit connection domain0.00005414Direct
Cyclophilin-like0.0009166Direct
PH0987 N-terminal domain-like0.001047Inherited
Aspartate/ornithine carbamoyltransferase0.1353Inherited
PreATP-grasp domain0.2341Inherited
Methylglyoxal synthase-like1Inherited


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Family

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SCOP termFDR (all)Annotation (direct or inherited)
HCP-like0Direct
Imidazolonepropionase-like0Direct
Zn metallo-beta-lactamase0Direct
Imidazolonepropionase-like0Direct
beta-Lactamase/D-ala carboxypeptidase0Direct
Transthyretin (synonym: prealbumin)0Direct
LamB/YcsF-like0Direct
Hydantoinase (dihydropyrimidinase)0Direct
Dihydroorotase0Direct
Hydantoinase (dihydropyrimidinase), catalytic domain0Direct
Carbamoyl phosphate synthetase, small subunit N-terminal domain0.00001703Direct
Carbamoyl phosphate synthetase, large subunit connection domain0.0000751Direct
PH0987 C-terminal domain-like0.0009926Direct
BC N-terminal domain-like0.004351Inherited
BC ATP-binding domain-like0.004954Inherited
Aspartate/ornithine carbamoyltransferase0.1626Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Glycoside hydrolase/deacetylase0Direct
Composite domain of metallo-dependent hydrolases0Direct
Transthyretin (synonym: prealbumin)0Direct
beta-lactamase/transpeptidase-like0Direct
HCP-like0Direct
Metallo-dependent hydrolases0Direct
Metallo-hydrolase/oxidoreductase0.000000001412Direct
Carbamoyl phosphate synthetase, small subunit N-terminal domain0.000009711Direct
Carbamoyl phosphate synthetase, large subunit connection domain0.00004346Direct
Cyclophilin-like0.0007559Direct
PH0987 N-terminal domain-like0.0008648Direct
Aspartate/ornithine carbamoyltransferase0.1188Inherited
PreATP-grasp domain0.2087Inherited
Methylglyoxal synthase-like1Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
51338,51556
  • 51338 - Composite domain of metallo-dependent hydrolases
  • 51556 - Metallo-dependent hydrolases
  • 0Direct
    52335,51556
  • 52335 - Methylglyoxal synthase-like
  • 51556 - Metallo-dependent hydrolases
  • 0Direct
    51556,51338
  • 51556 - Metallo-dependent hydrolases
  • 51338 - Composite domain of metallo-dependent hydrolases
  • 0Direct
    52317,52440
  • 52317 - Class I glutamine amidotransferase-like
  • 52440 - PreATP-grasp domain
  • 0.000000000000002108Direct
    52021,52317
  • 52021 - Carbamoyl phosphate synthetase, small subunit N-terminal domain
  • 52317 - Class I glutamine amidotransferase-like
  • 0.000009711Direct
    56059,52335
  • 56059 - Glutathione synthetase ATP-binding domain-like
  • 52335 - Methylglyoxal synthase-like
  • 0.00002408Direct
    48108,52440
  • 48108 - Carbamoyl phosphate synthetase, large subunit connection domain
  • 52440 - PreATP-grasp domain
  • 0.00003973Direct
    56059,48108
  • 56059 - Glutathione synthetase ATP-binding domain-like
  • 48108 - Carbamoyl phosphate synthetase, large subunit connection domain
  • 0.00004217Direct
    160467,50891
  • 160467 - PH0987 N-terminal domain-like
  • 50891 - Cyclophilin-like
  • 0.0008648Direct
    52440,56059
  • 52440 - PreATP-grasp domain
  • 56059 - Glutathione synthetase ATP-binding domain-like
  • 0.1972Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    52335,51556,51338
  • 52335 - Methylglyoxal synthase-like
  • 51556 - Metallo-dependent hydrolases
  • 51338 - Composite domain of metallo-dependent hydrolases
  • 0Direct
    56059,52335,51556
  • 56059 - Glutathione synthetase ATP-binding domain-like
  • 52335 - Methylglyoxal synthase-like
  • 51556 - Metallo-dependent hydrolases
  • 0Direct
    52021,52317,52440
  • 52021 - Carbamoyl phosphate synthetase, small subunit N-terminal domain
  • 52317 - Class I glutamine amidotransferase-like
  • 52440 - PreATP-grasp domain
  • 0.000000000000002108Direct
    52317,52440,56059
  • 52317 - Class I glutamine amidotransferase-like
  • 52440 - PreATP-grasp domain
  • 56059 - Glutathione synthetase ATP-binding domain-like
  • 0.000000000000002108Direct
    52440,56059,52335
  • 52440 - PreATP-grasp domain
  • 56059 - Glutathione synthetase ATP-binding domain-like
  • 52335 - Methylglyoxal synthase-like
  • 0.00002331Direct
    56059,48108,52440
  • 56059 - Glutathione synthetase ATP-binding domain-like
  • 48108 - Carbamoyl phosphate synthetase, large subunit connection domain
  • 52440 - PreATP-grasp domain
  • 0.00003856Direct
    48108,52440,56059
  • 48108 - Carbamoyl phosphate synthetase, large subunit connection domain
  • 52440 - PreATP-grasp domain
  • 56059 - Glutathione synthetase ATP-binding domain-like
  • 0.00003973Direct
    52440,56059,48108
  • 52440 - PreATP-grasp domain
  • 56059 - Glutathione synthetase ATP-binding domain-like
  • 48108 - Carbamoyl phosphate synthetase, large subunit connection domain
  • 0.00004217Direct
    51338,51556,51338
  • 51338 - Composite domain of metallo-dependent hydrolases
  • 51556 - Metallo-dependent hydrolases
  • 51338 - Composite domain of metallo-dependent hydrolases
  • 0.3801Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
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