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Enzyme Commission (EC): In cyclic amidines

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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Root: EC Hierarchy (from IntEnz release 70)

Shortest distance to current term (+ for parents, - for children) EC term [EC ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + 3:   root [root] <7>
+ + 2:   Hydrolases [3] <13>(395|668) (394|417|206)
+ 1:   Acting on carbon-nitrogen bonds, other than peptide bonds [3.5] <6>(72|104) (72|40|18)
0:   In cyclic amidines [3.5.4] <49>(17|22) (17|10|3)
- 1:   1-pyrroline-4-hydroxy-2-carboxylate deaminase [3.5.4.22](0|0) (0|0|0)
- 1:   5'-deoxyadenosine deaminase [3.5.4.41](2|2) (2|1|0)
- 1:   8-oxoguanine deaminase [3.5.4.32](0|0) (0|0|0)
- 1:   ADP deaminase [3.5.4.7](0|0) (0|0|0)
- 1:   AMP deaminase [3.5.4.6](1|1) (1|0|0)
- 1:   ATP deaminase [3.5.4.18](0|0) (0|0|0)
- 1:   Adenine deaminase [3.5.4.2](2|1) (2|1|0)
- 1:   Adenosine deaminase [3.5.4.4](1|3) (1|1|0)
- 1:   Adenosine-phosphate deaminase [3.5.4.17](0|0) (0|0|0)
- 1:   Aminodeoxyfutalosine deaminase [3.5.4.40](1|1) (1|0|0)
- 1:   Aminoimidazolase [3.5.4.8](0|0) (0|0|0)
- 1:   Blasticidin-S deaminase [3.5.4.23](0|1) (0|0|0)
- 1:   Creatinine deaminase [3.5.4.21](0|0) (0|0|0)
- 1:   Cytidine deaminase [3.5.4.5](1|1) (1|1|0)
- 1:   Cytosine deaminase [3.5.4.1](0|1) (0|0|0)
- 1:   Diaminohydroxyphosphoribosylaminopyrimidine deaminase [3.5.4.26](2|2) (2|1|0)
- 1:   Double-stranded RNA adenine deaminase [3.5.4.37](2|2) (2|1|1)
- 1:   Ectoine hydrolase [3.5.4.44](0|0) (0|0|0)
- 1:   GTP cyclohydrolase I [3.5.4.16](1|1) (1|0|0)
- 1:   GTP cyclohydrolase II [3.5.4.25](2|2) (2|1|0)
- 1:   GTP cyclohydrolase IIa [3.5.4.29](0|0) (0|0|0)
- 1:   GTP cyclohydrolase IV [3.5.4.39](0|0) (0|0|0)
- 1:   Guanine deaminase [3.5.4.3](2|1) (2|1|0)
- 1:   Guanosine deaminase [3.5.4.15](0|0) (0|0|0)
- 1:   Hydroxydechloroatrazine ethylaminohydrolase [3.5.4.43](0|0) (0|0|0)
- 1:   IMP cyclohydrolase [3.5.4.10](3|3) (3|1|0)
- 1:   Melamine deaminase [3.5.4.45](0|0) (0|0|0)
- 1:   Methenyltetrahydrofolate cyclohydrolase [3.5.4.9](2|2) (2|1|0)
- 1:   Methenyltetrahydromethanopterin cyclohydrolase [3.5.4.27](1|1) (1|0|0)
- 1:   N-isopropylammelide isopropylaminohydrolase [3.5.4.42](0|0) (0|0|0)
- 1:   Phosphoribosyl-AMP cyclohydrolase [3.5.4.19](2|3) (2|2|1)
- 1:   Pterin deaminase [3.5.4.11](0|0) (0|0|0)
- 1:   Pyrithiamine deaminase [3.5.4.20](0|0) (0|0|0)
- 1:   S-adenosylhomocysteine deaminase [3.5.4.28](2|2) (2|1|1)
- 1:   S-methyl-5'-thioadenosine deaminase [3.5.4.31](2|2) (2|1|1)
- 1:   Sepiapterin deaminase [3.5.4.24](0|0) (0|0|0)
- 1:   Single-stranded DNA cytosine deaminase [3.5.4.38](1|0) (1|1|0)
- 1:   Transferred entry: 3.5.4.31 [3.5.4.n1](0|0) (0|0|0)
- 1:   Transferred entry: 3.5.4.39 [3.5.4.n2](0|0) (0|0|0)
- 1:   Transferred entry: 3.5.4.45 [3.5.4.n3](0|0) (0|0|0)
- 1:   Transferred entry: 3.5.4.5 [3.5.4.14](0|0) (0|0|0)
- 1:   cAMP deaminase [3.5.4.46](0|0) (0|0|0)
- 1:   dCMP deaminase [3.5.4.12](1|1) (1|0|0)
- 1:   dCTP deaminase [3.5.4.13](1|1) (1|0|0)
- 1:   dCTP deaminase (dUMP-forming) [3.5.4.30](1|1) (1|0|0)
- 1:   mRNA(cytosine(6666)) deaminase [3.5.4.36](1|0) (1|0|0)
- 1:   tRNA(Ala)(adenine(37)) deaminase [3.5.4.34](0|0) (0|0|0)
- 1:   tRNA(adenine(34)) deaminase [3.5.4.33](1|1) (1|0|0)
- 1:   tRNA(cytosine(8)) deaminase [3.5.4.35](0|0) (0|0|0)


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
Methenyltetrahydromethanopterin cyclohydrolase0Direct
RibA-like0Direct
Methylglyoxal synthase-like0Direct
Archaeal IMP cyclohydrolase PurO0Direct
Tetrahydrobiopterin biosynthesis enzymes-like0Direct
YrdC/RibB0Direct
dUTPase-like0Direct
NAD(P)-binding Rossmann-fold domains0Direct
HisI-like0Direct
Cytidine deaminase-like0Direct
Aminoacid dehydrogenase-like, N-terminal domain0Direct
all-alpha NTP pyrophosphatases0Direct
Dihydrofolate reductase-like0.00000000007735Direct
dsRNA-binding domain-like0.3782Inherited
Metallo-dependent hydrolases0.4846Inherited
"Winged helix" DNA-binding domain1Inherited
Composite domain of metallo-dependent hydrolases1Inherited


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Family

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SCOP termFDR (all)Annotation (direct or inherited)
Cytosine deaminase catalytic domain0Direct
Aminoacid dehydrogenase-like, C-terminal domain0Direct
RibA-like0Direct
RibD C-terminal domain-like0Direct
Archaeal IMP cyclohydrolase PurO0Direct
HisI-like0Direct
dUTPase-like0Direct
SAH/MTA deaminase-like0Direct
Adenosine/AMP deaminase0Direct
GTP cyclohydrolase I0Direct
Inosicase0Direct
Cytidine deaminase0Direct
Z-DNA binding domain0Direct
SAH/MTA deaminase-like0Direct
3,4-dihydroxy-2-butanone 4-phosphate synthase, DHBP synthase, RibB0Direct
Deoxycytidylate deaminase-like0Direct
HisE-like (PRA-PH)0Direct
Tetrahydrofolate dehydrogenase/cyclohydrolase0Direct
AICAR transformylase domain of bifunctional purine biosynthesis enzyme ATIC0Direct
Methenyltetrahydromethanopterin cyclohydrolase0Direct
L-histidinol dehydrogenase HisD0.07434Inherited
Double-stranded RNA-binding domain (dsRBD)0.4711Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Tetrahydrobiopterin biosynthesis enzymes-like0Direct
Cytidine deaminase-like0Direct
Methenyltetrahydromethanopterin cyclohydrolase0Direct
all-alpha NTP pyrophosphatases0Direct
Archaeal IMP cyclohydrolase PurO0Direct
Methylglyoxal synthase-like0Direct
NAD(P)-binding Rossmann-fold domains0Direct
RibA-like0Direct
Aminoacid dehydrogenase-like, N-terminal domain0Direct
HisI-like0Direct
dUTPase-like0Direct
YrdC/RibB0Direct
Dihydrofolate reductase-like0.00000000005674Direct
dsRNA-binding domain-like0.3428Inherited
Metallo-dependent hydrolases0.4424Inherited
Composite domain of metallo-dependent hydrolases1Inherited
"Winged helix" DNA-binding domain1Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
101386,53720
  • 101386 - all-alpha NTP pyrophosphatases
  • 53720 - ALDH-like
  • 0Direct
    53223,51735
  • 53223 - Aminoacid dehydrogenase-like, N-terminal domain
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 0Direct
    53927,53927
  • 53927 - Cytidine deaminase-like
  • 53927 - Cytidine deaminase-like
  • 0Direct
    53927,53597
  • 53927 - Cytidine deaminase-like
  • 53597 - Dihydrofolate reductase-like
  • 0Direct
    141734,101386
  • 141734 - HisI-like
  • 101386 - all-alpha NTP pyrophosphatases
  • 0Direct
    55821,142695
  • 55821 - YrdC/RibB
  • 142695 - RibA-like
  • 0Direct
    52335,53927
  • 52335 - Methylglyoxal synthase-like
  • 53927 - Cytidine deaminase-like
  • 0Direct
    54768,54768
  • 54768 - dsRNA-binding domain-like
  • 54768 - dsRNA-binding domain-like
  • 0.000005016Direct
    51338,51556
  • 51338 - Composite domain of metallo-dependent hydrolases
  • 51556 - Metallo-dependent hydrolases
  • 1Inherited
    51556,51338
  • 51556 - Metallo-dependent hydrolases
  • 51338 - Composite domain of metallo-dependent hydrolases
  • 1Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    141734,101386,53720
  • 141734 - HisI-like
  • 101386 - all-alpha NTP pyrophosphatases
  • 53720 - ALDH-like
  • 0Direct
    54768,54768,54768
  • 54768 - dsRNA-binding domain-like
  • 54768 - dsRNA-binding domain-like
  • 54768 - dsRNA-binding domain-like
  • 0Direct
    51338,51556,51338
  • 51338 - Composite domain of metallo-dependent hydrolases
  • 51556 - Metallo-dependent hydrolases
  • 51338 - Composite domain of metallo-dependent hydrolases
  • 1Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
    (show help)