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Enzyme Commission (EC): Intramolecular oxidoreductases

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Root: EC Hierarchy (from IntEnz release 70)

Shortest distance to current term (+ for parents, - for children) EC term [EC ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + 2:   root [root] <7>
+ 1:   Isomerases [5] <7>(128|160) (128|76|32)
0:   Intramolecular oxidoreductases [5.3] <5>(40|53) (40|16|6)
- 1:   Interconverting aldoses and ketoses [5.3.1] <37>(15|25) (15|6|1)
- 1:   Transposing C=C bonds [5.3.3] <22>(15|13) (15|6|3)
- 1:   Other intramolecular oxidoreductases [5.3.99] <12>(9|8) (9|1|0)
- 1:   Interconverting keto- and enol-groups [5.3.2] <9>(4|5) (4|1|0)
- 1:   Transposing S-S bonds [5.3.4] <1>(3|3) (3|2|2)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
Thioesterase/thiol ester dehydrase-isomerase0Direct
Xylose isomerase-like0Direct
Thioredoxin-like0Direct
RmlC-like cupins0Direct
Triosephosphate isomerase (TIM)0Direct
SIS domain0Direct
Ribose/Galactose isomerase RpiB/AlsB0Direct
Allene oxide cyclase-like0Direct
Lipocalins0Direct
NagB/RpiA/CoA transferase-like0Direct
Nudix0Direct
Ribulose-phoshate binding barrel0Direct
ClpP/crotonase0Direct
Metallo-dependent hydrolases0Direct
ERP29 C domain-like0Direct
D-ribose-5-phosphate isomerase (RpiA), lid domain0Direct
FMN-linked oxidoreductases0Direct
Tautomerase/MIF0Direct
FucI/AraA N-terminal and middle domains0Direct
Acyl-CoA binding protein0Direct
FucI/AraA C-terminal domain-like0Direct
6-phosphogluconate dehydrogenase C-terminal domain-like0.000000000004036Direct
MAPEG domain-like0.0000003251Direct
Growth factor receptor domain0.00003205Direct
FumA C-terminal domain-like0.0001748Direct
HSP20-like chaperones0.001703Inherited
Di-copper centre-containing domain0.002659Inherited
RuBisCo, C-terminal domain0.01227Inherited
RuBisCO, large subunit, small (N-terminal) domain0.01582Inherited
CBS-domain pair0.01696Inherited
FAH0.05115Inherited
NTF2-like0.1526Inherited
GST C-terminal domain-like0.2382Inherited
Cytochrome P4500.6196Inherited
FAD/NAD(P)-binding domain1Inherited
Nucleotide-diphospho-sugar transferases1Inherited
Class I glutamine amidotransferase-like1Inherited
Dimeric alpha+beta barrel1Inherited
Diaminopimelate epimerase-like1Inherited
NAD(P)-binding Rossmann-fold domains1Inherited


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Family

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SCOP termFDR (all)Annotation (direct or inherited)
Type I phosphomannose isomerase0Direct
MIF-related0Direct
ERP29 C domain-like0Direct
Phosphoglucose isomerase, PGI0Direct
4-oxalocrotonate tautomerase-like0Direct
IolI-like0Direct
AraA C-terminal domain-like0Direct
Tryptophan biosynthesis enzymes0Direct
PhzC/PhzF-like0Direct
Ketosteroid isomerase-like0Direct
PA3566-like0Direct
IPP isomerase-like0Direct
IF2B-like0Direct
L-fucose isomerase, N-terminal and second domains0Direct
L-rhamnose isomerase0Direct
L-fucose isomerase, C-terminal domain0Direct
Uronate isomerase-like0Direct
Muconalactone isomerase, MLI0Direct
AraA N-terminal and middle domain-like0Direct
mono-SIS domain0Direct
beta-Hydroxydecanol thiol ester dehydrase0Direct
Glucose-6-phosphate isomerase, GPI0Direct
D-ribose-5-phosphate isomerase (RpiA), lid domain0Direct
PDI-like0Direct
Ribose/Galactose isomerase RpiB/AlsB0Direct
Histidine biosynthesis enzymes0Direct
Xylose isomerase0Direct
Hypothetical protein YgbM (EC1530)0Direct
FMN-linked oxidoreductases0Direct
KduI-like0Direct
Acyl-CoA binding protein0Direct
Triosephosphate isomerase (TIM)0Direct
Allene oxide cyclase-like0Direct
Retinol binding protein-like0Direct
D-ribose-5-phosphate isomerase (RpiA), catalytic domain0Direct
Crotonase-like3.692e-16Direct
HCDH C-domain-like0.000000000001266Direct
6-phosphogluconate dehydrogenase-like, N-terminal domain0.000000000005598Direct
mannose-1-phosphate guanylyl transferase0.0000001791Direct
MAPEG domain0.000005765Direct
Co-chaperone p23-like0.00005191Direct
FumA C-terminal domain-like0.0001891Direct
Growth factor receptor domain0.0007148Direct
double-SIS domain0.0103Inherited
CBS-domain pair0.0171Inherited
FAH0.05255Inherited
RuBisCo, large subunit, C-terminal domain0.06012Inherited
Ribulose 1,5-bisphosphate carboxylase-oxygenase0.06591Inherited
Glutathione S-transferase (GST), C-terminal domain0.1968Inherited
Glutathione S-transferase (GST), N-terminal domain0.1968Inherited
Cytochrome P4500.6834Inherited
Class I glutamine amidotransferases (GAT)1Inherited
Tyrosine-dependent oxidoreductases1Inherited


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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Triosephosphate isomerase (TIM)0Direct
ClpP/crotonase0Direct
D-ribose-5-phosphate isomerase (RpiA), lid domain0Direct
FucI/AraA N-terminal and middle domains0Direct
Lipocalins0Direct
Tautomerase/MIF0Direct
NagB/RpiA/CoA transferase-like0Direct
SIS domain0Direct
Allene oxide cyclase-like0Direct
Acyl-CoA binding protein0Direct
FucI/AraA C-terminal domain-like0Direct
RmlC-like cupins0Direct
Xylose isomerase-like0Direct
Metallo-dependent hydrolases0Direct
FMN-linked oxidoreductases0Direct
ERP29 C domain-like0Direct
Thioredoxin-like0Direct
Thioesterase/thiol ester dehydrase-isomerase0Direct
Ribulose-phoshate binding barrel0Direct
Nudix0Direct
Ribose/Galactose isomerase RpiB/AlsB0Direct
6-phosphogluconate dehydrogenase C-terminal domain-like0.000000000002913Direct
MAPEG domain-like0.0000002512Direct
Growth factor receptor domain0.00002562Direct
FumA C-terminal domain-like0.000142Direct
HSP20-like chaperones0.001415Inherited
Di-copper centre-containing domain0.002222Inherited
RuBisCo, C-terminal domain0.01043Inherited
RuBisCO, large subunit, small (N-terminal) domain0.01349Inherited
CBS-domain pair0.01447Inherited
FAH0.04425Inherited
NTF2-like0.1345Inherited
GST C-terminal domain-like0.2125Inherited
Cytochrome P4500.5689Inherited
Diaminopimelate epimerase-like1Inherited
Nucleotide-diphospho-sugar transferases1Inherited
Dimeric alpha+beta barrel1Inherited
Class I glutamine amidotransferase-like1Inherited
FAD/NAD(P)-binding domain1Inherited
NAD(P)-binding Rossmann-fold domains1Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
53697,54631
  • 53697 - SIS domain
  • 54631 - CBS-domain pair
  • 0Direct
    56529,56529
  • 56529 - FAH
  • 56529 - FAH
  • 0Direct
    52317,51366
  • 52317 - Class I glutamine amidotransferase-like
  • 51366 - Ribulose-phoshate binding barrel
  • 0Direct
    51366,51366
  • 51366 - Ribulose-phoshate binding barrel
  • 51366 - Ribulose-phoshate binding barrel
  • 0Direct
    100950,75445
  • 100950 - NagB/RpiA/CoA transferase-like
  • 75445 - D-ribose-5-phosphate isomerase (RpiA), lid domain
  • 0Direct
    52833,47933
  • 52833 - Thioredoxin-like
  • 47933 - ERP29 C domain-like
  • 0Direct
    53743,50443
  • 53743 - FucI/AraA N-terminal and middle domains
  • 50443 - FucI/AraA C-terminal domain-like
  • 0Direct
    52833,52833
  • 52833 - Thioredoxin-like
  • 52833 - Thioredoxin-like
  • 0Direct
    47027,52096
  • 47027 - Acyl-CoA binding protein
  • 52096 - ClpP/crotonase
  • 0Direct
    48179,48179
  • 48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like
  • 48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like
  • 0.0000000000003693Direct
    52096,51735
  • 52096 - ClpP/crotonase
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 0.000000000002012Direct
    51735,48179
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like
  • 0.000000000002913Direct
    53448,51182
  • 53448 - Nucleotide-diphospho-sugar transferases
  • 51182 - RmlC-like cupins
  • 0.0000001083Direct
    48179,52096
  • 48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like
  • 52096 - ClpP/crotonase
  • 0.000000358Direct
    54966,51649
  • 54966 - RuBisCO, large subunit, small (N-terminal) domain
  • 51649 - RuBisCo, C-terminal domain
  • 0.01025Inherited
    52833,47616
  • 52833 - Thioredoxin-like
  • 47616 - GST C-terminal domain-like
  • 0.186Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    52317,51366,51366
  • 52317 - Class I glutamine amidotransferase-like
  • 51366 - Ribulose-phoshate binding barrel
  • 51366 - Ribulose-phoshate binding barrel
  • 0Direct
    52833,52833,52833
  • 52833 - Thioredoxin-like
  • 52833 - Thioredoxin-like
  • 52833 - Thioredoxin-like
  • 0Direct
    52833,52833,47933
  • 52833 - Thioredoxin-like
  • 52833 - Thioredoxin-like
  • 47933 - ERP29 C domain-like
  • 0Direct
    51735,48179,48179
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like
  • 48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like
  • 0.0000000000003693Direct
    52096,51735,48179
  • 52096 - ClpP/crotonase
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like
  • 0.000000000002012Direct
    48179,48179,52096
  • 48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like
  • 48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like
  • 52096 - ClpP/crotonase
  • 0.000000358Direct


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
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