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Enzyme Commission (EC): Catalysing the translocation of hydrons

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Root: EC Hierarchy (from IntEnz release 70)

Shortest distance to current term (+ for parents, - for children) EC term [EC ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + 2:   root [root] <7>
+ 1:   Translocases [7] <6>(40|39) (39|33|19)
0:   Catalysing the translocation of hydrons [7.1] <3>(28|25) (27|15|9)
- 1:   Hydron translocation or charge separation linked to oxidoreductase reactions [7.1.1] <8>(20|18) (19|9|3)
- 1:   Hydron translocation linked to the hydrolysis of a nucleoside triphosphate [7.1.2] <2>(8|7) (8|6|6)
- 1:   Hydron translocation linked to the hydrolysis of diphosphate [7.1.3] <1>(0|0) (0|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
HydB/Nqo4-like0Direct
Non-globular alpha+beta subunits of globular proteins0Direct
Nqo1C-terminal domain-like0Direct
Nqo1 middle domain-like0Direct
N-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
Nqo5-like0Direct
HydA/Nqo6-like0Direct
Transmembrane di-heme cytochromes0Direct
C-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
ISP domain0Direct
ISP transmembrane anchor0Direct
Formate dehydrogenase/DMSO reductase, domains 1-30.000000000000665Direct
4Fe-4S ferredoxins0.000000001041Direct
Hedgehog/intein (Hint) domain0.000000813Direct
Homing endonucleases0.00001015Direct
Cytochrome c0.00001748Direct
Nqo1 FMN-binding domain-like0.0005031Direct
P-loop containing nucleoside triphosphate hydrolases0.002394Inherited
SCOP hierarchy in SUPERFAMILY0.01317Inherited
Cytochrome c oxidase subunit I-like0.01594Inherited
Formate/glycerate dehydrogenase catalytic domain-like0.07252Inherited
DHS-like NAD/FAD-binding domain0.1597Inherited
Thioredoxin-like0.4965Inherited
2Fe-2S ferredoxin-like1Inherited
HAD-like1Inherited
NAD(P)-binding Rossmann-fold domains1Inherited
Calcium ATPase, transduction domain A1Inherited
Calcium ATPase, transmembrane domain M1Inherited


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Family

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SCOP termFDR (all)Annotation (direct or inherited)
Nqo5-like0Direct
Nqo4-like0Direct
Cytochrome b of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase)0Direct
Ferredoxin domains from multidomain proteins0Direct
RecA protein-like (ATPase-domain)0Direct
Rieske iron-sulfur protein (ISP)0Direct
Nqo1C-terminal domain-like0Direct
Nq06-like0Direct
ISP transmembrane anchor0Direct
N-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
NQO2-like0Direct
Nqo1 middle domain-like0Direct
Ubiquinol-cytochrome c reductase 8 kDa protein0Direct
C-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
Transhydrogenase domain III (dIII)7.36e-16Direct
Formate dehydrogenase/DMSO reductase, domains 1-30.00000000001699Direct
L-alanine dehydrogenase-like0.0000000003418Direct
Nqo1 FMN-binding domain-like0.0004196Direct
Intein (protein splicing domain)0.0004325Direct
Cytochrome c oxidase subunit I-like0.02044Inherited
2Fe-2S ferredoxin domains from multidomain proteins0.06782Inherited
Formate/glycerate dehydrogenases, NAD-domain0.1161Inherited
Meta-cation ATPase, catalytic domain P1Inherited
Calcium ATPase, transduction domain A1Inherited
Calcium ATPase, transmembrane domain M1Inherited


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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Nqo1C-terminal domain-like0Direct
ISP transmembrane anchor0Direct
HydA/Nqo6-like0Direct
Non-globular alpha+beta subunits of globular proteins0Direct
ISP domain0Direct
N-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
Nqo1 middle domain-like0Direct
C-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
Transmembrane di-heme cytochromes0Direct
Nqo5-like0Direct
HydB/Nqo4-like0Direct
Formate dehydrogenase/DMSO reductase, domains 1-30.0000000000004767Direct
4Fe-4S ferredoxins0.0000000007758Direct
Hedgehog/intein (Hint) domain0.0000006338Direct
Homing endonucleases0.000008046Direct
Cytochrome c0.00001393Direct
Nqo1 FMN-binding domain-like0.0004121Direct
P-loop containing nucleoside triphosphate hydrolases0.001997Inherited
Cytochrome c oxidase subunit I-like0.01359Inherited
Formate/glycerate dehydrogenase catalytic domain-like0.06303Inherited
DHS-like NAD/FAD-binding domain0.1409Inherited
Thioredoxin-like0.4538Inherited
2Fe-2S ferredoxin-like1Inherited
NAD(P)-binding Rossmann-fold domains1Inherited
Calcium ATPase, transduction domain A1Inherited
HAD-like1Inherited
Calcium ATPase, transmembrane domain M1Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
54292,54862
  • 54292 - 2Fe-2S ferredoxin-like
  • 54862 - 4Fe-4S ferredoxins
  • 0Direct
    52540,47917
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 47917 - C-terminal domain of alpha and beta subunits of F1 ATP synthase
  • 0Direct
    81502,50022
  • 81502 - ISP transmembrane anchor
  • 50022 - ISP domain
  • 0Direct
    -7,50022
  • -7 - CATH
  • 50022 - ISP domain
  • 0Direct
    142019,142984
  • 142019 - Nqo1 FMN-binding domain-like
  • 142984 - Nqo1 middle domain-like
  • 0Direct
    56568,81502
  • 56568 - Non-globular alpha+beta subunits of globular proteins
  • 81502 - ISP transmembrane anchor
  • 0Direct
    50615,52540
  • 50615 - N-terminal domain of alpha and beta subunits of F1 ATP synthase
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    142984,140490
  • 142984 - Nqo1 middle domain-like
  • 140490 - Nqo1C-terminal domain-like
  • 0Direct
    54862,53706
  • 54862 - 4Fe-4S ferredoxins
  • 53706 - Formate dehydrogenase/DMSO reductase, domains 1-3
  • 0Direct
    52540,51294
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 51294 - Hedgehog/intein (Hint) domain
  • 0.00000000001412Direct
    55608,52540
  • 55608 - Homing endonucleases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.00000000007762Direct
    51294,55608
  • 51294 - Hedgehog/intein (Hint) domain
  • 55608 - Homing endonucleases
  • 0.00000008908Direct
    46626,46626
  • 46626 - Cytochrome c
  • 46626 - Cytochrome c
  • 0.0000006238Direct
    52283,51735
  • 52283 - Formate/glycerate dehydrogenase catalytic domain-like
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 0.05911Inherited
    56784,81665
  • 56784 - HAD-like
  • 81665 - Calcium ATPase, transmembrane domain M
  • 1Inherited

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    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    54292,54862,53706
  • 54292 - 2Fe-2S ferredoxin-like
  • 54862 - 4Fe-4S ferredoxins
  • 53706 - Formate dehydrogenase/DMSO reductase, domains 1-3
  • 0Direct
    50615,52540,47917
  • 50615 - N-terminal domain of alpha and beta subunits of F1 ATP synthase
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 47917 - C-terminal domain of alpha and beta subunits of F1 ATP synthase
  • 0Direct
    50615,52540,52540
  • 50615 - N-terminal domain of alpha and beta subunits of F1 ATP synthase
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    56568,81502,50022
  • 56568 - Non-globular alpha+beta subunits of globular proteins
  • 81502 - ISP transmembrane anchor
  • 50022 - ISP domain
  • 0Direct
    142019,142984,140490
  • 142019 - Nqo1 FMN-binding domain-like
  • 142984 - Nqo1 middle domain-like
  • 140490 - Nqo1C-terminal domain-like
  • 0Direct
    55608,52540,47917
  • 55608 - Homing endonucleases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 47917 - C-terminal domain of alpha and beta subunits of F1 ATP synthase
  • 0Direct
    52540,52540,47917
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 47917 - C-terminal domain of alpha and beta subunits of F1 ATP synthase
  • 0Direct
    52540,51294,55608
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 51294 - Hedgehog/intein (Hint) domain
  • 55608 - Homing endonucleases
  • 0.000000001211Direct
    51294,55608,52540
  • 51294 - Hedgehog/intein (Hint) domain
  • 55608 - Homing endonucleases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.0000001046Direct


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
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