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Fly Anatomy (FA): multicellular structure
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Phenotype Ontology
Like Gene Ontology (GO), phenotypy ontology classifies and organizes gene-mutant/null phenotypic information from the very general at the top to more specific terms in the directed acyclic graph (DAG) by viewing an individual term as a node and its relations to parental terms (allowing for multiple parents) as directed edges. To navigate this hierarchy, we display all parental phenotypic terms to the current phenotypic term of interest ordered by their shortest distances to the current term. Also, only direct children phenotypic terms of the current phenotypic term are listed. Phenotype ontologies we have incorporated are as follows:
- Disease Ontology (DO) Ontology (DO) DO semantically integrates disease and medical vocabularies through extensive cross mapping of DO terms to MeSH, ICD, NCI thesaurus, SNOMED and OMIM.
- Human Phenotype (HP) Ontology (HP) HP captures phenotypic abnormalities that are described in OMIM, along with the corresponding disease-causing genes. It includes three complementary biological concepts: Mode_of_Inheritance (MI), ONset_and_clinical_course (ON), and Phenotypic_Abnormality (PA).
- Mouse Phenotype (MP) Ontology (MP) MP describes phenotypes of the mouse after a specific gene is genetically disrupted. Using it, Mouse Genome Informatics (MGI) provides high-coverate gene-level phenotypes for the mouse.
- Worm Phenotype (WP) Ontology (WP) WP classifies and organizes phenotype descriptions for C. elegans and other nematodes. Using it, WormBase provides primary resource for phenotype annotations for C. elegans.
- Yeast Phenotype (YP) Ontology (YP) Based on YP which is the major contributor to the Ascomycete phenotype ontology, Saccharomyces Genome Database (SGD) provides single mutant phenotypes for every gene in the yeast genome.
- Fly Phenotype (FP) Ontology (FP) FP refers to FlyBase controlled vocabulary. Specifically, a structured controlled vocabulary is used for the annotation of alleles (for their mutagen etc) in FlyBase.
- Fly Anatomy (FA) Ontology (FA) FA is a structured controlled vocabulary of the anatomy of Drosophila melanogaster, used for the description of phenotypes and where a gene is expressed.
- Zebrafish Anatomy (ZA) Ontology (ZA) ZA displays anatomical terms of the zebrafish using standard anatomical nomenclature, together with affected genes.
- Xenopus Anatomy (XA) Ontology (XA) XA represents the lineage of tissues and the timing of development for frogs (Xenopus laevis and Xenopus tropicalis). It is used to annotate Xenopus gene expression patterns and mutant and morphant phenotypes.
- Arabidopsis Plant Ontology (AP) Ontology (AP) As a major contributor to Plant Ontology which describes plant anatomical and morphological structures (AN) and growth and developmental stages (DE), the Arabidopsis Information Resource (TAIR) provides arabidopsis plant ontology annotations for the model higher plant Arabidopsis thaliana.
- Enzyme Commission (EC) Ontology (EC) Each enzyme is allocated a four-digit EC number, the first three digits of which define the reaction catalysed and the fourth of which is a unique identifier (serial number). Each enzyme is also assigned a systematic name that uniquely defines the reaction catalysed.
- DrugBank ATC (DB) Ontology (DB) In the Anatomical Therapeutic Chemical (ATC) classification system, drugs are classified in groups at five different levels according to the organ or system (1st level, anatomical main group) on which they act and their therapeutic (2nd level, therapeutic subgroup), pharmacological (3rd level, pharmacological subgroup) and chemical properties (4th level, chemical subgroup; 5th level, chemical substance). Only drugs in DrugBank are considered.
- UniProtKB KeyWords (KW) Ontology (KW) Keywords in UniProtKB are controlled vocabulary, providing a summary of the entry content and are used to index UniProtKB/Swiss-Prot entries based on 10 categories (the category "Technical term" being excluded here). Each keyword is attributed manually to UniProtKB/Swiss-Prot entries and automatically to UniProtKB/TrEMBL entries (according to specific annotation rules).
- UniProtKB UniPathway (UP) Ontology (UP) UP is a fully manually curated resource for the representation and annotation of metabolic pathways, being used as controlled vocabulary for pathway annotation in UniProtKB.
Structural Domain Phenotype Ontology and its Annotations
Structural Classification of Proteins (SCOP) classifies evolutionary-related domains into Superfamily level and Family level. Using the phenotype ontologies above, we have generated the domain-centric phenotype annotations, and further identified those phenotype terms which are the most informative to annotate SCOP domains. Promisingly, domain-centric phenotypic annotations can serve as an alternative starting point to explore genotype-phenotype relationships. We provide several relevant files for the download, including the annotation and the corresponding ontology for each phenotype ontology.
- Structural Domain Disease Ontology (DO) Ontology (SDDO) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2DO.txt, and the corresponding ontology:SDDO.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Human Phenotype (HP) Ontology (SDHP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2HP.txt, and the corresponding ontology:SDHP.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Mouse Phenotype (MP) Ontology (SDMP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2MP.txt, and the corresponding ontology:SDMP.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Worm Phenotype (WP) Ontology (SDWP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2WP.txt, and the corresponding ontology:SDWP.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Yeast Phenotype (YP) Ontology (SDYP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2YP.txt, and the corresponding ontology:SDYP.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Fly Phenotype (FP) Ontology (SDFP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2FP.txt, and the corresponding ontology:SDFP.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Fly Anatomy (FA) Ontology (SDFA) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2FA.txt, and the corresponding ontology:SDFA.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Zebrafish Anatomy (ZA) Ontology (SDZA) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2ZA.txt, and the corresponding ontology:SDZA.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Xenopus Anatomy (XA) Ontology (SDXA) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2XA.txt, and the corresponding ontology:SDXA.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Arabidopsis Plant Ontology (AP) Ontology (SDAP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2AP.txt, and the corresponding ontology:SDAP.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Enzyme Commission (EC) Ontology (SDEC) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2EC.txt, and the corresponding ontology:SDEC.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain DrugBank ATC (DB) Ontology (SDDB) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2DB.txt, and the corresponding ontology:SDDB.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain UniProtKB KeyWords (KW) Ontology (SDKW) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2KW.txt, and the corresponding ontology:SDKW.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain UniProtKB UniPathway (UP) Ontology (SDUP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2UP.txt, and the corresponding ontology:SDUP.txt) and mysql tables (Domain2PO.sql.gz).
Supra-domain Phenotype Ontology and its Annotations
Although domain-centric annotations hold great promise in describing phenotypic nature of independent domains, most domains themselves may not just work alone. In multi-domain proteins, they may be combined together to form distinct domain architectures. The recombination of the existing domains is considered as one of major driving forces for phenotypic diversificaation. As an extension, we have also generated supra-domain phenotype ontology and its annotations. Compared to domain-centric phenotype ontology and annotations (SCOP domains at the Superfamily level and Family level), this version focuses on supra-domains and individual SCOP domains ONLY at the Superfamily level. Besides, in terms of individual superfamilies, their annotations from the domain-centric version may be different from those from supra-domains version. Depending on your focus, the former should be used for the consideration of both the Superfamily level and Family level, otherwise the latter should be used if you are interested in domain combinations. Also, we provide several relevant files for the download, including the annotation and the corresponding ontology for each phenotype ontology.
- Supra-domain Domain Disease Ontology (DO) Ontology (SPDO) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2DO.txt, and the corresponding ontology:SPDO.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Human Phenotype (HP) Ontology (SPHO) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2HP.txt, and the corresponding ontology:SPHO.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Mouse Phenotype (MP) Ontology (SPMP) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2MP.txt, and the corresponding ontology:SPMP.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Worm Phenotype (WP) Ontology (SPWP) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2WP.txt, and the corresponding ontology:SPWP.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Yeast Phenotype (YP) Ontology (SPYP) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2YP.txt, and the corresponding ontology:SPYP.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Fly Phenotype (FP) Ontology (SPFP) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2FP.txt, and the corresponding ontology:SPFP.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Fly Anatomy (FA) Ontology (SPFA) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2FA.txt, and the corresponding ontology:SPFA.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Zebrafish Anatomy (ZA) Ontology (SPZA) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2ZA.txt, and the corresponding ontology:SPZA.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Xenopus Anatomy (XA) Ontology (SPXA) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2XA.txt, and the corresponding ontology:SPXA.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Arabidopsis Plant Ontology (AP) Ontology (SPAP) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2AP.txt, and the corresponding ontology:SPAP.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Enzyme Commission (EC) Ontology (SPEC) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2EC.txt, and the corresponding ontology:SPEC.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain DrugBank ATC (DB) Ontology (SPDB) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2DB.txt, and the corresponding ontology:SPDB.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain UniProtKB KeyWords (KW) Ontology (SPKW) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2KW.txt, and the corresponding ontology:SPKW.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain UniProtKB UniPathway (UP) Ontology (SPUP) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2UP.txt, and the corresponding ontology:SPUP.txt) and mysql tables (SP2PO.sql.gz).
Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]
Root: FA Hierarchy (fly anatomy from FlyBase anatomy ontology)
Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]
Superfamily(show details)
Superfamily domains annotated to this FA term (Not in SDFA)
Highlighted in gray are those with FDR_all>0.001
SCOP term | FDR (all) | Annotation (direct or inherited) |
EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | DIRECT |
L30e-like | 0 | DIRECT |
Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | DIRECT |
DNA-binding domain | 0 | DIRECT |
Zn-dependent exopeptidases | 0 | DIRECT |
GroEL equatorial domain-like | 0 | DIRECT |
Zinc beta-ribbon | 0 | DIRECT |
N-terminal nucleophile aminohydrolases (Ntn hydrolases) | 0 | DIRECT |
CCCH zinc finger | 0 | DIRECT |
Bromodomain | 0 | DIRECT |
B-box zinc-binding domain | 0 | DIRECT |
ALDH-like | 0 | DIRECT |
Formin homology 2 domain (FH2 domain) | 0 | DIRECT |
Acyl-CoA dehydrogenase C-terminal domain-like | 0 | DIRECT |
Cysteine proteinases | 0 | DIRECT |
dsRNA-binding domain-like | 0 | DIRECT |
S15/NS1 RNA-binding domain | 0 | DIRECT |
C-terminal, gelsolin-like domain of Sec23/24 | 0 | DIRECT |
Cadherin-like | 0 | DIRECT |
Smc hinge domain | 0 | DIRECT |
HLH, helix-loop-helix DNA-binding domain | 0 | DIRECT |
CBS-domain pair | 0 | DIRECT |
SH3-domain | 0 | DIRECT |
Cysteine-rich domain | 0 | DIRECT |
Nucleotidylyl transferase | 0 | DIRECT |
Retrovirus zinc finger-like domains | 0 | DIRECT |
F-box domain | 0 | DIRECT |
Orange domain-like | 0 | DIRECT |
ARID-like | 0 | DIRECT |
Clathrin adaptor appendage domain | 0 | DIRECT |
Thiamin diphosphate-binding fold (THDP-binding) | 0 | DIRECT |
Sec1/munc18-like (SM) proteins | 0 | DIRECT |
Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor | 0 | DIRECT |
A DNA-binding domain in eukaryotic transcription factors | 0 | DIRECT |
SNARE-like | 0 | DIRECT |
Alkaline phosphatase-like | 0 | DIRECT |
4Fe-4S ferredoxins | 0 | DIRECT |
Rhodanese/Cell cycle control phosphatase | 0 | DIRECT |
BAR/IMD domain-like | 0 | DIRECT |
p53-like transcription factors | 0 | DIRECT |
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0 | DIRECT |
Second domain of FERM | 0 | DIRECT |
RNI-like | 0 | DIRECT |
Succinyl-CoA synthetase domains | 0 | DIRECT |
Glutamine synthetase/guanido kinase | 0 | DIRECT |
Growth factor receptor domain | 0 | DIRECT |
Hemocyanin, N-terminal domain | 0 | DIRECT |
Ribonuclease H-like | 0 | DIRECT |
lambda repressor-like DNA-binding domains | 0 | DIRECT |
PIN domain-like | 0 | DIRECT |
RNA-binding domain, RBD | 0 | DIRECT |
ENTH/VHS domain | 0 | DIRECT |
(Phosphotyrosine protein) phosphatases II | 0 | DIRECT |
Leukotriene A4 hydrolase N-terminal domain | 0 | DIRECT |
Neurotransmitter-gated ion-channel transmembrane pore | 0 | DIRECT |
SOCS box-like | 0 | DIRECT |
TIMP-like | 0 | DIRECT |
SAND domain-like | 0 | DIRECT |
SMAD/FHA domain | 0 | DIRECT |
E set domains | 0 | DIRECT |
Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | DIRECT |
beta-sandwich domain of Sec23/24 | 0 | DIRECT |
NTF2-like | 0 | DIRECT |
Cystine-knot cytokines | 0 | DIRECT |
C-type lectin-like | 0 | DIRECT |
Cysteine-rich DNA binding domain, (DM domain) | 0 | DIRECT |
Supernatant protein factor (SPF), C-terminal domain | 0 | DIRECT |
Kelch motif | 0 | DIRECT |
Calponin-homology domain, CH-domain | 0 | DIRECT |
PapD-like | 0 | DIRECT |
Galactose-binding domain-like | 0 | DIRECT |
NHL repeat | 0 | DIRECT |
Glucocorticoid receptor-like (DNA-binding domain) | 0 | DIRECT |
MIR domain | 0 | DIRECT |
2Fe-2S ferredoxin-like | 0 | DIRECT |
Cullin repeat-like | 0 | DIRECT |
Activating enzymes of the ubiquitin-like proteins | 0 | DIRECT |
PX domain | 0 | DIRECT |
TSP-1 type 1 repeat | 0 | DIRECT |
SET domain | 0 | DIRECT |
L27 domain | 0 | DIRECT |
Fibrinogen C-terminal domain-like | 0 | DIRECT |
Tropomyosin | 0 | DIRECT |
FabD/lysophospholipase-like | 0 | DIRECT |
CAD & PB1 domains | 0 | DIRECT |
Mitochondrial carrier | 0 | DIRECT |
Serpins | 0 | DIRECT |
HD-domain/PDEase-like | 0 | DIRECT |
GINS helical bundle-like | 0 | DIRECT |
Putative DNA-binding domain | 0 | DIRECT |
Chromo domain-like | 0 | DIRECT |
Mob1/phocein | 0 | DIRECT |
TRAF domain-like | 0 | DIRECT |
Nicotinic receptor ligand binding domain-like | 0 | DIRECT |
Acid phosphatase/Vanadium-dependent haloperoxidase | 0 | DIRECT |
Tudor/PWWP/MBT | 0 | DIRECT |
Metalloproteases ("zincins"), catalytic domain | 0 | DIRECT |
PYP-like sensor domain (PAS domain) | 0 | DIRECT |
Sema domain | 0 | DIRECT |
Periplasmic binding protein-like I | 0 | DIRECT |
Actin-like ATPase domain | 0 | DIRECT |
Transducin (alpha subunit), insertion domain | 0 | DIRECT |
Tubulin C-terminal domain-like | 0 | DIRECT |
Multidrug efflux transporter AcrB transmembrane domain | 0 | DIRECT |
Macro domain-like | 0 | DIRECT |
MFS general substrate transporter | 0 | DIRECT |
Metallo-dependent phosphatases | 0 | DIRECT |
Hect, E3 ligase catalytic domain | 0 | DIRECT |
BRCT domain | 0 | DIRECT |
Frizzled cysteine-rich domain | 0 | DIRECT |
Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 | 0 | DIRECT |
TATA-box binding protein-like | 0 | DIRECT |
Toll/Interleukin receptor TIR domain | 0 | DIRECT |
Complement control module/SCR domain | 0 | DIRECT |
Kazal-type serine protease inhibitors | 0 | DIRECT |
t-snare proteins | 0 | DIRECT |
Arginase/deacetylase | 0 | DIRECT |
EF-hand | 0 | DIRECT |
UDP-Glycosyltransferase/glycogen phosphorylase | 0 | DIRECT |
SMAD MH1 domain | 0 | DIRECT |
Regulator of G-protein signaling, RGS | 0 | DIRECT |
ACP-like | 0 | DIRECT |
Glutathione synthetase ATP-binding domain-like | 0 | DIRECT |
GroEL apical domain-like | 0 | DIRECT |
Clavaminate synthase-like | 0 | DIRECT |
Integrin domains | 0 | DIRECT |
"Winged helix" DNA-binding domain | 0 | DIRECT |
SPOC domain-like | 0 | DIRECT |
TPR-like | 0 | DIRECT |
Nucleotide-diphospho-sugar transferases | 0 | DIRECT |
HMG-box | 0 | DIRECT |
Plexin repeat | 0 | DIRECT |
Spermadhesin, CUB domain | 0 | DIRECT |
DBL homology domain (DH-domain) | 0 | DIRECT |
YVTN repeat-like/Quinoprotein amine dehydrogenase | 0 | DIRECT |
SAP domain | 0 | DIRECT |
Acyl-CoA N-acyltransferases (Nat) | 0 | DIRECT |
SIS domain | 0 | DIRECT |
(Trans)glycosidases | 0 | DIRECT |
FAD-linked reductases, C-terminal domain | 0 | DIRECT |
EGF/Laminin | 0 | DIRECT |
Ypt/Rab-GAP domain of gyp1p | 0 | DIRECT |
FAD/NAD(P)-binding domain | 0 | DIRECT |
SH2 domain | 0 | DIRECT |
N-acetylmuramoyl-L-alanine amidase-like | 0 | DIRECT |
Snake toxin-like | 0 | DIRECT |
6-phosphogluconate dehydrogenase C-terminal domain-like | 0 | DIRECT |
Ferritin-like | 0 | DIRECT |
Protein prenylyltransferase | 0 | DIRECT |
Nucleic acid-binding proteins | 0 | DIRECT |
FtsH protease domain-like | 0 | DIRECT |
YWTD domain | 0 | DIRECT |
Ferredoxin reductase-like, C-terminal NADP-linked domain | 0 | DIRECT |
L domain-like | 0 | DIRECT |
GroEL-intermediate domain like | 0 | DIRECT |
CRAL/TRIO domain | 0 | DIRECT |
R3H domain | 0 | DIRECT |
Periplasmic binding protein-like II | 0 | DIRECT |
cAMP-binding domain-like | 0 | DIRECT |
Class I glutamine amidotransferase-like | 0 | DIRECT |
Protease propeptides/inhibitors | 0 | DIRECT |
FKBP-like | 0 | DIRECT |
Fibronectin type III | 0 | DIRECT |
C2 domain (Calcium/lipid-binding domain, CaLB) | 0 | DIRECT |
Terpenoid synthases | 0 | DIRECT |
Sm-like ribonucleoproteins | 0 | DIRECT |
LDL receptor-like module | 0 | DIRECT |
HSP20-like chaperones | 0 | DIRECT |
Cytochrome P450 | 0 | DIRECT |
NAD kinase/diacylglycerol kinase-like | 0 | DIRECT |
Multidrug resistance efflux transporter EmrE | 0 | DIRECT |
Calcium ATPase, transduction domain A | 0 | DIRECT |
WW domain | 0 | DIRECT |
PriA/YqbF domain | 0 | DIRECT |
Sec7 domain | 0 | DIRECT |
alpha-catenin/vinculin-like | 0 | DIRECT |
Actin depolymerizing proteins | 0 | DIRECT |
SNF-like | 0 | DIRECT |
Immunoglobulin | 0 | DIRECT |
SNARE fusion complex | 0 | DIRECT |
Phosphoglycerate mutase-like | 0 | DIRECT |
DNA/RNA polymerases | 0 | DIRECT |
Translation proteins SH3-like domain | 0 | DIRECT |
SCOP hierarchy in SUPERFAMILY | 0 | DIRECT |
DNase I-like | 0 | DIRECT |
Adenine nucleotide alpha hydrolases-like | 0 | DIRECT |
Acyl-CoA dehydrogenase NM domain-like | 0 | DIRECT |
Quinoprotein alcohol dehydrogenase-like | 0 | DIRECT |
PDZ domain-like | 0 | DIRECT |
SAM/Pointed domain | 0 | DIRECT |
vWA-like | 0 | DIRECT |
Cap-Gly domain | 0 | DIRECT |
Caspase-like | 0 | DIRECT |
RNase III domain-like | 0 | DIRECT |
Cullin homology domain | 0 | DIRECT |
HAD-like | 0 | DIRECT |
ArfGap/RecO-like zinc finger | 0 | DIRECT |
Concanavalin A-like lectins/glucanases | 0 | DIRECT |
PreATP-grasp domain | 0 | DIRECT |
FYVE/PHD zinc finger | 0 | DIRECT |
Metal cation-transporting ATPase, ATP-binding domain N | 0 | DIRECT |
Nuclear receptor ligand-binding domain | 0 | DIRECT |
PAP/OAS1 substrate-binding domain | 0 | DIRECT |
UBC-like | 0 | DIRECT |
Glycerol-3-phosphate (1)-acyltransferase | 0 | DIRECT |
post-AAA+ oligomerization domain-like | 0 | DIRECT |
PH domain-like | 0 | DIRECT |
Spectrin repeat | 0 | DIRECT |
Calcium ATPase, transmembrane domain M | 0 | DIRECT |
GTPase activation domain, GAP | 0 | DIRECT |
Ribosomal protein S5 domain 2-like | 0 | DIRECT |
Riboflavin synthase domain-like | 0 | DIRECT |
FnI-like domain | 0 | DIRECT |
HIT/MYND zinc finger-like | 0 | DIRECT |
SAICAR synthase-like | 0 | DIRECT |
Tetraspanin | 0 | DIRECT |
PAZ domain | 0 | DIRECT |
Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain | 0 | DIRECT |
Ran binding protein zinc finger-like | 0 | DIRECT |
Rhomboid-like | 0 | DIRECT |
Cytokine | 0 | DIRECT |
DEATH domain | 0 | DIRECT |
Histone-fold | 0 | DIRECT |
RCC1/BLIP-II | 0 | DIRECT |
Protein kinase-like (PK-like) | 0.1105 | INHERITED FROM: organ system subdivision || larval imaginal tissue || imaginal disc || embryonic/larval integumentary system || egg || synaptic neuropil || organism subdivision || embryo || female-specific anatomical entity || nervous system || ovariole || pupal/adult digestive system || portion of tissue || somatic cell of ovariole || pupa || intestinal stem cell |
beta-beta-alpha zinc fingers | 0.1588 | INHERITED FROM: organ system subdivision || tagma || adult segment || adult tagma || region of integument || adult thorax || appendage || integumentary system || organism subdivision || organ system || adult thoracic segment || serotonergic neuron || adult integumentary system || thorax || adult || adult mesothoracic segment || subesophageal ganglion neuron || thoracic segment || segment |
Homeodomain-like | 0.5127 | INHERITED FROM: organ system subdivision || tagma || sense organ || adult segment || embryonic/larval sense organ || alula || intercalary segment || head segment || larval metathoracic segment || adult external head || gland || larval segment || multi-tissue structure || transverse nerve || denticle belt || embryonic supraesophageal neuromere || region of integument || larval neuromere || embryonic head || commissure || adult thorax || larval tagma || interneuron || dorsal margin photoreceptor || appendage || larval prothoracic segment || cell cluster organ || abdominal segment || embryonic neuroblast || integumentary system || organism subdivision || ganglion || mouthpart || parasegment || antennal segment || tract neuropil || basiproboscis || embryonic/larval muscle system || stomatogastric nervous system || embryonic/larval thoracic/abdominal lateral sensory cluster || extended germ band embryo || head capsule || organ system || metathoracic segment || prothoracic ventral intersegmental muscle || embryonic head segment || dorsal margin ommatidium || embryonic fiber tract founder cluster || appendage segment || adult integumentary system || neuron projection bundle || uniglomerular antennal lobe projection neuron || thorax || distiproboscis || tritocerebrum || A1-7 ventral acute muscle 1 || gonadal sheath proper primordium || embryonic/larval dorsal vessel || eo-type sensillum || EL neuron || adult || wing hinge || embryonic protocerebrum || embryonic/larval supraesophageal ganglion || segment of leg || T1 beard || embryonic segment || adult metathoracic segment || pretarsus || adult antennal segment || abdomen || maxillary palpus || female terminalia || mesothoracic tergum || embryonic/larval subesophageal ganglion || embryonic mesothoracic segment || embryonic thoracic segment || central brain || embryonic/larval sensillum || thoracic neuroblast || embryonic tagma || metathoracic ventral denticle belt || embryonic brain || U neuron || antennal lobe glomerulus VA1v || head bristle || presumptive embryonic/larval nervous system || presumptive embryonic/larval central nervous system || dorsal rim area || ventral nerve cord primordium || antenna || integumentary process || embryonic/larval neuron || trunk mesoderm derivative || gnathal segment || larval abdomen || ventral nervous system || integument of larval mesothoracic segment || developing embryonic structure || proboscis || segment |
RING/U-box | 0.5153 | INHERITED FROM: embryonic/larval garland organ || embryonic/larval garland cell || garland cell |
Ankyrin repeat | 0.5854 | INHERITED FROM: Johnston organ neuron |
POZ domain | 0.6688 | INHERITED FROM: terminal filament |
P-loop containing nucleoside triphosphate hydrolases | 0.6927 | INHERITED FROM: germline cyst || reproductive system || gonad |
Leucine zipper domain | 0.8675 | INHERITED FROM: adult heart || adult dorsal vessel || embryonic dorsal epidermis |
Tubulin nucleotide-binding domain-like | 0.9336 | INHERITED FROM: spermatid || fat cell || spermatid cyst |
Invertebrate chitin-binding proteins | 0.9469 | INHERITED FROM: embryonic/larval tracheal system || embryonic/larval integumentary system || embryonic/larval dorsal trunk || primary trachea || embryonic/larval trachea || embryonic/larval cuticle || tracheal system |
CoA-dependent acyltransferases | 0.9599 | INHERITED FROM: skeletal muscle of thorax || adult somatic muscle || skeletal muscle of mesothorax || adult muscle system || flight muscle |
SCOP term | FDR (all) | Annotation (direct or inherited) |
EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | Direct |
L30e-like | 0 | Direct |
Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | Direct |
DNA-binding domain | 0 | Direct |
Zn-dependent exopeptidases | 0 | Direct |
GroEL equatorial domain-like | 0 | Direct |
Zinc beta-ribbon | 0 | Direct |
N-terminal nucleophile aminohydrolases (Ntn hydrolases) | 0 | Direct |
CCCH zinc finger | 0 | Direct |
Bromodomain | 0 | Direct |
B-box zinc-binding domain | 0 | Direct |
ALDH-like | 0 | Direct |
Formin homology 2 domain (FH2 domain) | 0 | Direct |
Acyl-CoA dehydrogenase C-terminal domain-like | 0 | Direct |
Cysteine proteinases | 0 | Direct |
dsRNA-binding domain-like | 0 | Direct |
S15/NS1 RNA-binding domain | 0 | Direct |
C-terminal, gelsolin-like domain of Sec23/24 | 0 | Direct |
Cadherin-like | 0 | Direct |
Smc hinge domain | 0 | Direct |
HLH, helix-loop-helix DNA-binding domain | 0 | Direct |
CBS-domain pair | 0 | Direct |
SH3-domain | 0 | Direct |
Cysteine-rich domain | 0 | Direct |
Nucleotidylyl transferase | 0 | Direct |
Retrovirus zinc finger-like domains | 0 | Direct |
F-box domain | 0 | Direct |
Orange domain-like | 0 | Direct |
ARID-like | 0 | Direct |
Clathrin adaptor appendage domain | 0 | Direct |
Thiamin diphosphate-binding fold (THDP-binding) | 0 | Direct |
Sec1/munc18-like (SM) proteins | 0 | Direct |
Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor | 0 | Direct |
A DNA-binding domain in eukaryotic transcription factors | 0 | Direct |
SNARE-like | 0 | Direct |
Alkaline phosphatase-like | 0 | Direct |
4Fe-4S ferredoxins | 0 | Direct |
Rhodanese/Cell cycle control phosphatase | 0 | Direct |
BAR/IMD domain-like | 0 | Direct |
p53-like transcription factors | 0 | Direct |
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0 | Direct |
Second domain of FERM | 0 | Direct |
RNI-like | 0 | Direct |
Succinyl-CoA synthetase domains | 0 | Direct |
Glutamine synthetase/guanido kinase | 0 | Direct |
Growth factor receptor domain | 0 | Direct |
Hemocyanin, N-terminal domain | 0 | Direct |
Ribonuclease H-like | 0 | Direct |
lambda repressor-like DNA-binding domains | 0 | Direct |
PIN domain-like | 0 | Direct |
RNA-binding domain, RBD | 0 | Direct |
ENTH/VHS domain | 0 | Direct |
(Phosphotyrosine protein) phosphatases II | 0 | Direct |
Leukotriene A4 hydrolase N-terminal domain | 0 | Direct |
Neurotransmitter-gated ion-channel transmembrane pore | 0 | Direct |
SOCS box-like | 0 | Direct |
TIMP-like | 0 | Direct |
SAND domain-like | 0 | Direct |
SMAD/FHA domain | 0 | Direct |
E set domains | 0 | Direct |
Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | Direct |
beta-sandwich domain of Sec23/24 | 0 | Direct |
NTF2-like | 0 | Direct |
Cystine-knot cytokines | 0 | Direct |
C-type lectin-like | 0 | Direct |
Cysteine-rich DNA binding domain, (DM domain) | 0 | Direct |
Supernatant protein factor (SPF), C-terminal domain | 0 | Direct |
Kelch motif | 0 | Direct |
Calponin-homology domain, CH-domain | 0 | Direct |
PapD-like | 0 | Direct |
Galactose-binding domain-like | 0 | Direct |
NHL repeat | 0 | Direct |
Glucocorticoid receptor-like (DNA-binding domain) | 0 | Direct |
MIR domain | 0 | Direct |
2Fe-2S ferredoxin-like | 0 | Direct |
Cullin repeat-like | 0 | Direct |
Activating enzymes of the ubiquitin-like proteins | 0 | Direct |
PX domain | 0 | Direct |
TSP-1 type 1 repeat | 0 | Direct |
SET domain | 0 | Direct |
L27 domain | 0 | Direct |
Fibrinogen C-terminal domain-like | 0 | Direct |
Tropomyosin | 0 | Direct |
FabD/lysophospholipase-like | 0 | Direct |
CAD & PB1 domains | 0 | Direct |
Mitochondrial carrier | 0 | Direct |
Serpins | 0 | Direct |
HD-domain/PDEase-like | 0 | Direct |
GINS helical bundle-like | 0 | Direct |
Putative DNA-binding domain | 0 | Direct |
Chromo domain-like | 0 | Direct |
Mob1/phocein | 0 | Direct |
TRAF domain-like | 0 | Direct |
Nicotinic receptor ligand binding domain-like | 0 | Direct |
Acid phosphatase/Vanadium-dependent haloperoxidase | 0 | Direct |
Tudor/PWWP/MBT | 0 | Direct |
Metalloproteases ("zincins"), catalytic domain | 0 | Direct |
PYP-like sensor domain (PAS domain) | 0 | Direct |
Sema domain | 0 | Direct |
Periplasmic binding protein-like I | 0 | Direct |
Actin-like ATPase domain | 0 | Direct |
Transducin (alpha subunit), insertion domain | 0 | Direct |
Tubulin C-terminal domain-like | 0 | Direct |
Multidrug efflux transporter AcrB transmembrane domain | 0 | Direct |
Macro domain-like | 0 | Direct |
MFS general substrate transporter | 0 | Direct |
Metallo-dependent phosphatases | 0 | Direct |
Hect, E3 ligase catalytic domain | 0 | Direct |
BRCT domain | 0 | Direct |
Frizzled cysteine-rich domain | 0 | Direct |
Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 | 0 | Direct |
TATA-box binding protein-like | 0 | Direct |
Toll/Interleukin receptor TIR domain | 0 | Direct |
Complement control module/SCR domain | 0 | Direct |
Kazal-type serine protease inhibitors | 0 | Direct |
t-snare proteins | 0 | Direct |
Arginase/deacetylase | 0 | Direct |
EF-hand | 0 | Direct |
UDP-Glycosyltransferase/glycogen phosphorylase | 0 | Direct |
SMAD MH1 domain | 0 | Direct |
Regulator of G-protein signaling, RGS | 0 | Direct |
ACP-like | 0 | Direct |
Glutathione synthetase ATP-binding domain-like | 0 | Direct |
GroEL apical domain-like | 0 | Direct |
Clavaminate synthase-like | 0 | Direct |
Integrin domains | 0 | Direct |
"Winged helix" DNA-binding domain | 0 | Direct |
SPOC domain-like | 0 | Direct |
TPR-like | 0 | Direct |
Nucleotide-diphospho-sugar transferases | 0 | Direct |
HMG-box | 0 | Direct |
Plexin repeat | 0 | Direct |
Spermadhesin, CUB domain | 0 | Direct |
DBL homology domain (DH-domain) | 0 | Direct |
YVTN repeat-like/Quinoprotein amine dehydrogenase | 0 | Direct |
SAP domain | 0 | Direct |
Acyl-CoA N-acyltransferases (Nat) | 0 | Direct |
SIS domain | 0 | Direct |
(Trans)glycosidases | 0 | Direct |
FAD-linked reductases, C-terminal domain | 0 | Direct |
EGF/Laminin | 0 | Direct |
Ypt/Rab-GAP domain of gyp1p | 0 | Direct |
FAD/NAD(P)-binding domain | 0 | Direct |
SH2 domain | 0 | Direct |
N-acetylmuramoyl-L-alanine amidase-like | 0 | Direct |
Snake toxin-like | 0 | Direct |
6-phosphogluconate dehydrogenase C-terminal domain-like | 0 | Direct |
Ferritin-like | 0 | Direct |
Protein prenylyltransferase | 0 | Direct |
Nucleic acid-binding proteins | 0 | Direct |
FtsH protease domain-like | 0 | Direct |
YWTD domain | 0 | Direct |
Ferredoxin reductase-like, C-terminal NADP-linked domain | 0 | Direct |
L domain-like | 0 | Direct |
GroEL-intermediate domain like | 0 | Direct |
CRAL/TRIO domain | 0 | Direct |
R3H domain | 0 | Direct |
Periplasmic binding protein-like II | 0 | Direct |
cAMP-binding domain-like | 0 | Direct |
Class I glutamine amidotransferase-like | 0 | Direct |
Protease propeptides/inhibitors | 0 | Direct |
FKBP-like | 0 | Direct |
Fibronectin type III | 0 | Direct |
C2 domain (Calcium/lipid-binding domain, CaLB) | 0 | Direct |
Terpenoid synthases | 0 | Direct |
Sm-like ribonucleoproteins | 0 | Direct |
LDL receptor-like module | 0 | Direct |
HSP20-like chaperones | 0 | Direct |
Cytochrome P450 | 0 | Direct |
NAD kinase/diacylglycerol kinase-like | 0 | Direct |
Multidrug resistance efflux transporter EmrE | 0 | Direct |
Calcium ATPase, transduction domain A | 0 | Direct |
WW domain | 0 | Direct |
PriA/YqbF domain | 0 | Direct |
Sec7 domain | 0 | Direct |
alpha-catenin/vinculin-like | 0 | Direct |
Actin depolymerizing proteins | 0 | Direct |
SNF-like | 0 | Direct |
Immunoglobulin | 0 | Direct |
SNARE fusion complex | 0 | Direct |
Phosphoglycerate mutase-like | 0 | Direct |
DNA/RNA polymerases | 0 | Direct |
Translation proteins SH3-like domain | 0 | Direct |
SCOP hierarchy in SUPERFAMILY | 0 | Direct |
DNase I-like | 0 | Direct |
Adenine nucleotide alpha hydrolases-like | 0 | Direct |
Acyl-CoA dehydrogenase NM domain-like | 0 | Direct |
Quinoprotein alcohol dehydrogenase-like | 0 | Direct |
PDZ domain-like | 0 | Direct |
SAM/Pointed domain | 0 | Direct |
vWA-like | 0 | Direct |
Cap-Gly domain | 0 | Direct |
Caspase-like | 0 | Direct |
RNase III domain-like | 0 | Direct |
Cullin homology domain | 0 | Direct |
HAD-like | 0 | Direct |
ArfGap/RecO-like zinc finger | 0 | Direct |
Concanavalin A-like lectins/glucanases | 0 | Direct |
PreATP-grasp domain | 0 | Direct |
FYVE/PHD zinc finger | 0 | Direct |
Metal cation-transporting ATPase, ATP-binding domain N | 0 | Direct |
Nuclear receptor ligand-binding domain | 0 | Direct |
PAP/OAS1 substrate-binding domain | 0 | Direct |
UBC-like | 0 | Direct |
Glycerol-3-phosphate (1)-acyltransferase | 0 | Direct |
post-AAA+ oligomerization domain-like | 0 | Direct |
PH domain-like | 0 | Direct |
Spectrin repeat | 0 | Direct |
Calcium ATPase, transmembrane domain M | 0 | Direct |
GTPase activation domain, GAP | 0 | Direct |
Ribosomal protein S5 domain 2-like | 0 | Direct |
Riboflavin synthase domain-like | 0 | Direct |
FnI-like domain | 0 | Direct |
HIT/MYND zinc finger-like | 0 | Direct |
SAICAR synthase-like | 0 | Direct |
Tetraspanin | 0 | Direct |
PAZ domain | 0 | Direct |
Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain | 0 | Direct |
Ran binding protein zinc finger-like | 0 | Direct |
Rhomboid-like | 0 | Direct |
Cytokine | 0 | Direct |
DEATH domain | 0 | Direct |
Histone-fold | 0 | Direct |
RCC1/BLIP-II | 0 | Direct |
Protein kinase-like (PK-like) | 0.1105 | Inherited |
beta-beta-alpha zinc fingers | 0.1588 | Inherited |
Homeodomain-like | 0.5127 | Inherited |
RING/U-box | 0.5153 | Inherited |
Ankyrin repeat | 0.5854 | Inherited |
POZ domain | 0.6688 | Inherited |
P-loop containing nucleoside triphosphate hydrolases | 0.6927 | Inherited |
Leucine zipper domain | 0.8675 | Inherited |
Tubulin nucleotide-binding domain-like | 0.9336 | Inherited |
Invertebrate chitin-binding proteins | 0.9469 | Inherited |
CoA-dependent acyltransferases | 0.9599 | Inherited |
Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]
Family(show details)
Family domains annotated to this FA term (Not in SDFA)
Highlighted in gray are those with FDR_all>0.001
SCOP term | FDR (all) | Annotation (direct or inherited) |
Myb/SANT domain | 0 | DIRECT |
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0 | DIRECT |
Protein kinase cysteine-rich domain (cys2, phorbol-binding domain) | 0 | DIRECT |
EGF-type module | 0 | DIRECT |
RNase III catalytic domain-like | 0 | DIRECT |
Ngr ectodomain-like | 0 | DIRECT |
Cap-Gly domain | 0 | DIRECT |
Laminin G-like module | 0 | DIRECT |
Isoprenyl diphosphate synthases | 0 | DIRECT |
ets domain | 0 | DIRECT |
NLI interacting factor-like phosphatase | 0 | DIRECT |
MSP-like | 0 | DIRECT |
Caspase catalytic domain | 0 | DIRECT |
FHA domain | 0 | DIRECT |
Calmodulin-like | 0 | DIRECT |
Paired domain | 0 | DIRECT |
Transducin (alpha subunit), insertion domain | 0 | DIRECT |
Higher-molecular-weight phosphotyrosine protein phosphatases | 0 | DIRECT |
NHL repeat | 0 | DIRECT |
SNF-like | 0 | DIRECT |
Spermadhesin, CUB domain | 0 | DIRECT |
BC ATP-binding domain-like | 0 | DIRECT |
Eps15 homology domain (EH domain) | 0 | DIRECT |
Nucleosome core histones | 0 | DIRECT |
Ubiquitin carboxyl-terminal hydrolase, UCH | 0 | DIRECT |
Sm motif of small nuclear ribonucleoproteins, SNRNP | 0 | DIRECT |
DnaQ-like 3'-5' exonuclease | 0 | DIRECT |
Phosphatidylinositol phosphate kinase IIbeta, PIPK IIbeta | 0 | DIRECT |
Third domain of FERM | 0 | DIRECT |
Arthropod hemocyanin, C-terminal domain | 0 | DIRECT |
GMC oxidoreductases | 0 | DIRECT |
p120GAP domain-like | 0 | DIRECT |
CAD domain | 0 | DIRECT |
Double-stranded RNA-binding domain (dsRBD) | 0 | DIRECT |
Single strand DNA-binding domain, SSB | 0 | DIRECT |
Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 | 0 | DIRECT |
Sec7 domain | 0 | DIRECT |
C-type lectin domain | 0 | DIRECT |
Fibrinogen C-terminal domain-like | 0 | DIRECT |
Astacin | 0 | DIRECT |
N-acetylmuramoyl-L-alanine amidase-like | 0 | DIRECT |
Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | DIRECT |
Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor | 0 | DIRECT |
Rel/Dorsal transcription factors, DNA-binding domain | 0 | DIRECT |
Kelch motif | 0 | DIRECT |
Tubulin, C-terminal domain | 0 | DIRECT |
CoA-binding domain | 0 | DIRECT |
6-phosphogluconate dehydrogenase-like, N-terminal domain | 0 | DIRECT |
SH2 domain | 0 | DIRECT |
Tudor domain | 0 | DIRECT |
LDL receptor-like module | 0 | DIRECT |
MBT repeat | 0 | DIRECT |
PAZ domain | 0 | DIRECT |
DNA replication initiator (cdc21/cdc54) N-terminal domain | 0 | DIRECT |
TBP-associated factors, TAFs | 0 | DIRECT |
Dual specificity phosphatase-like | 0 | DIRECT |
Protein prenylyltransferase | 0 | DIRECT |
Pancreatic carboxypeptidases | 0 | DIRECT |
SAM (sterile alpha motif) domain | 0 | DIRECT |
Cold shock DNA-binding domain-like | 0 | DIRECT |
Phosphotyrosine-binding domain (PTB) | 0 | DIRECT |
Pyk2-associated protein beta ARF-GAP domain | 0 | DIRECT |
Tandem AAA-ATPase domain | 0 | DIRECT |
First domain of FERM | 0 | DIRECT |
Growth factor receptor domain | 0 | DIRECT |
Fibronectin type III | 0 | DIRECT |
A DNA-binding domain in eukaryotic transcription factors | 0 | DIRECT |
C-terminal, gelsolin-like domain of Sec23/24 | 0 | DIRECT |
Hect, E3 ligase catalytic domain | 0 | DIRECT |
Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | DIRECT |
R3H domain | 0 | DIRECT |
Hemocyanin, N-terminal domain | 0 | DIRECT |
DNA polymerase III clamp loader subunits, C-terminal domain | 0 | DIRECT |
Multidrug efflux transporter AcrB transmembrane domain | 0 | DIRECT |
SCF ubiquitin ligase complex WHB domain | 0 | DIRECT |
Erythroid transcription factor GATA-1 | 0 | DIRECT |
SOCS box-like | 0 | DIRECT |
Choline/Carnitine O-acyltransferase | 0 | DIRECT |
UBA domain | 0 | DIRECT |
BCR-homology GTPase activation domain (BH-domain) | 0 | DIRECT |
Dachshund-homology domain | 0 | DIRECT |
RecA protein-like (ATPase-domain) | 0 | DIRECT |
Fibroblast growth factors (FGF) | 0 | DIRECT |
SNARE fusion complex | 0 | DIRECT |
Leukotriene A4 hydrolase N-terminal domain | 0 | DIRECT |
Phoshoinositide 3-kinase (PI3K), catalytic domain | 0 | DIRECT |
PDZ domain | 0 | DIRECT |
Proteasome subunits | 0 | DIRECT |
PX domain | 0 | DIRECT |
t-snare proteins | 0 | DIRECT |
Metal cation-transporting ATPase, ATP-binding domain N | 0 | DIRECT |
Thioltransferase | 0 | DIRECT |
BAR domain | 0 | DIRECT |
N-acetyl transferase, NAT | 0 | DIRECT |
Leukotriene A4 hydrolase catalytic domain | 0 | DIRECT |
Nuclear receptor ligand-binding domain | 0 | DIRECT |
Frizzled cysteine-rich domain | 0 | DIRECT |
Group II chaperonin (CCT, TRIC), intermediate domain | 0 | DIRECT |
SMAD MH1 domain | 0 | DIRECT |
Cullin homology domain | 0 | DIRECT |
Neurotransmitter-gated ion-channel transmembrane pore | 0 | DIRECT |
Serpins | 0 | DIRECT |
Complement control module/SCR domain | 0 | DIRECT |
Myotubularin-like phosphatases | 0 | DIRECT |
Sec1/munc18-like (SM) proteins | 0 | DIRECT |
Nicotinic receptor ligand binding domain-like | 0 | DIRECT |
UBC-related | 0 | DIRECT |
TSP-1 type 1 repeat | 0 | DIRECT |
Synaptotagmin-like (S variant) | 0 | DIRECT |
FYVE, a phosphatidylinositol-3-phosphate binding domain | 0 | DIRECT |
YWTD domain | 0 | DIRECT |
Class I glutamine amidotransferases (GAT) | 0 | DIRECT |
SPRY domain | 0 | DIRECT |
Ubiquitin activating enzymes (UBA) | 0 | DIRECT |
Regulator of G-protein signaling, RGS | 0 | DIRECT |
Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain | 0 | DIRECT |
Spectrin repeat | 0 | DIRECT |
HMG-box | 0 | DIRECT |
HLH, helix-loop-helix DNA-binding domain | 0 | DIRECT |
DEATH domain, DD | 0 | DIRECT |
VHS domain | 0 | DIRECT |
Forkhead DNA-binding domain | 0 | DIRECT |
Actin/HSP70 | 0 | DIRECT |
Succinyl-CoA synthetase domains | 0 | DIRECT |
Pyridoxal-dependent decarboxylase | 0 | DIRECT |
NTF2-like | 0 | DIRECT |
ARID domain | 0 | DIRECT |
Cytochrome P450 | 0 | DIRECT |
Clathrin coat assembly domain | 0 | DIRECT |
Cofilin-like | 0 | DIRECT |
Tropomyosin | 0 | DIRECT |
DBL homology domain (DH-domain) | 0 | DIRECT |
Ran binding protein zinc finger-like | 0 | DIRECT |
Class I aminoacyl-tRNA synthetases (RS), catalytic domain | 0 | DIRECT |
Toll/Interleukin receptor TIR domain | 0 | DIRECT |
Cadherin | 0 | DIRECT |
Tyrosine-dependent oxidoreductases | 0 | DIRECT |
Protein kinases, catalytic subunit | 0 | DIRECT |
SMAD domain | 0 | DIRECT |
Class II glutamine amidotransferases | 0 | DIRECT |
Acetylcholinesterase-like | 0 | DIRECT |
Pleckstrin-homology domain (PH domain) | 0 | DIRECT |
LIM domain | 0 | DIRECT |
ZZ domain | 0 | DIRECT |
PLC-like (P variant) | 0 | DIRECT |
Regulator of chromosome condensation RCC1 | 0 | DIRECT |
Diacylglycerol kinase-like | 0 | DIRECT |
Extended AAA-ATPase domain | 0 | DIRECT |
NF-kappa-B/REL/DORSAL transcription factors, C-terminal domain | 0 | DIRECT |
SH3-domain | 0 | DIRECT |
Diap1 N-terninal region-like | 0 | DIRECT |
Calcium ATPase, transduction domain A | 0 | DIRECT |
Plexin repeat | 0 | DIRECT |
Pointed domain | 0 | DIRECT |
BTB/POZ domain | 0 | DIRECT |
B-box zinc-binding domain | 0 | DIRECT |
ALDH-like | 0 | DIRECT |
Neutral endopeptidase (neprilysin) | 0 | DIRECT |
Inositol polyphosphate 5-phosphatase (IPP5) | 0 | DIRECT |
Platelet-derived growth factor-like | 0 | DIRECT |
Extracellular domain of cell surface receptors | 0 | DIRECT |
BC N-terminal domain-like | 0 | DIRECT |
Histone deacetylase, HDAC | 0 | DIRECT |
Transforming growth factor (TGF)-beta | 0 | DIRECT |
EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | DIRECT |
Sema domain | 0 | DIRECT |
Hairy Orange domain | 0 | DIRECT |
FtsH protease domain-like | 0 | DIRECT |
L27 domain | 0 | DIRECT |
EF-hand modules in multidomain proteins | 0 | DIRECT |
Elongation factors | 0 | DIRECT |
WW domain | 0 | DIRECT |
Cysteine-rich DNA binding domain, (DM domain) | 0 | DIRECT |
Laminin-type module | 0 | DIRECT |
POU-specific domain | 0 | DIRECT |
Tetramerization domain of potassium channels | 0 | DIRECT |
Armadillo repeat | 0 | DIRECT |
Tetratricopeptide repeat (TPR) | 0 | DIRECT |
Mob1/phocein | 0 | DIRECT |
Rhomboid-like | 0 | DIRECT |
Chromo barrel domain | 0 | DIRECT |
Smc hinge domain | 0 | DIRECT |
CCCH zinc finger | 0 | DIRECT |
CBS-domain pair | 0 | DIRECT |
Transcriptional factor domain | 0 | DIRECT |
FAD-linked reductases, N-terminal domain | 0 | DIRECT |
SAP domain | 0 | DIRECT |
L-arabinose binding protein-like | 0 | DIRECT |
Canonical RBD | 0 | DIRECT |
Integrin domains | 0 | DIRECT |
Bromodomain | 0 | DIRECT |
T-box | 0 | DIRECT |
Pepsin-like | 0 | DIRECT |
I set domains | 0 | DIRECT |
CRAL/TRIO domain | 0 | DIRECT |
FKBP immunophilin/proline isomerase | 0 | DIRECT |
Hypoxia-inducible factor Hif2a, C-terminal domain | 0 | DIRECT |
Cell cycle control phosphatase, catalytic domain | 0 | DIRECT |
Group II chaperonin (CCT, TRIC), ATPase domain | 0 | DIRECT |
Ras-binding domain, RBD | 0 | DIRECT |
Group II chaperonin (CCT, TRIC), apical domain | 0 | DIRECT |
Phosphate binding protein-like | 0 | DIRECT |
2Fe-2S ferredoxin domains from multidomain proteins | 0 | DIRECT |
Zf-UBP | 0 | DIRECT |
F-box domain | 0 | DIRECT |
Cullin repeat | 0 | DIRECT |
PDEase | 0 | DIRECT |
PIWI domain | 0 | DIRECT |
acyl-CoA oxidase C-terminal domains | 0 | DIRECT |
Mitochondrial carrier | 0 | DIRECT |
PHD domain | 0 | DIRECT |
cAMP-binding domain | 0 | DIRECT |
Discoidin domain (FA58C, coagulation factor 5/8 C-terminal domain) | 0 | DIRECT |
Nucleotide and nucleoside kinases | 0 | DIRECT |
Protein serine/threonine phosphatase | 0 | DIRECT |
Second domain of FERM | 0 | DIRECT |
Formin homology 2 domain (FH2 domain) | 0 | DIRECT |
Retrovirus zinc finger-like domains | 0 | DIRECT |
Arrestin/Vps26-like | 0 | DIRECT |
Ubiquitin carboxyl-terminal hydrolase UCH-L | 0 | DIRECT |
Phoshoinositide 3-kinase (PI3K) helical domain | 0 | DIRECT |
TATA-box binding protein (TBP), C-terminal domain | 0 | DIRECT |
Histone lysine methyltransferases | 0 | DIRECT |
acyl-CoA oxidase N-terminal domains | 0 | DIRECT |
La domain | 0 | DIRECT |
THAP domain | 0 | DIRECT |
Motor proteins | 0 | DIRECT |
Nuclear receptor | 0 | DIRECT |
Homeodomain | 0 | DIRECT |
Chromo domain | 0 | DIRECT |
Calponin-homology domain, CH-domain | 0 | DIRECT |
MIR domain | 0 | DIRECT |
Clathrin adaptor core protein | 0 | DIRECT |
G proteins | 0.4069 | INHERITED FROM: circulatory system || embryonic/larval fat body || embryonic/larval adipose system || wing hair || hemocyte |
Classic zinc finger, C2H2 | 0.4254 | INHERITED FROM: adult segment || adult tagma || embryonic/larval head sensillum || region of integument || adult thorax || appendage || integumentary system || organism subdivision || adult integumentary system || thorax || embryonic ganglion mother cell || adult || adult mesothoracic segment || segment |
Ankyrin repeat | 0.5553 | INHERITED FROM: ventral multidendritic neuron || Johnston organ neuron |
Leucine zipper domain | 0.8518 | INHERITED FROM: adult heart || embryonic dorsal epidermis |
Ubiquitin-related | 0.8789 | INHERITED FROM: mushroom body extrinsic neuron |
Cyclin | 0.8931 | INHERITED FROM: germarium || tagmatic subdivision of organ system |
Tubulin, GTPase domain | 0.922 | INHERITED FROM: spermatid || fat cell || spermatid cyst |
SCOP term | FDR (all) | Annotation (direct or inherited) |
Myb/SANT domain | 0 | Direct |
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0 | Direct |
Protein kinase cysteine-rich domain (cys2, phorbol-binding domain) | 0 | Direct |
EGF-type module | 0 | Direct |
RNase III catalytic domain-like | 0 | Direct |
Ngr ectodomain-like | 0 | Direct |
Cap-Gly domain | 0 | Direct |
Laminin G-like module | 0 | Direct |
Isoprenyl diphosphate synthases | 0 | Direct |
ets domain | 0 | Direct |
NLI interacting factor-like phosphatase | 0 | Direct |
MSP-like | 0 | Direct |
Caspase catalytic domain | 0 | Direct |
FHA domain | 0 | Direct |
Calmodulin-like | 0 | Direct |
Paired domain | 0 | Direct |
Transducin (alpha subunit), insertion domain | 0 | Direct |
Higher-molecular-weight phosphotyrosine protein phosphatases | 0 | Direct |
NHL repeat | 0 | Direct |
SNF-like | 0 | Direct |
Spermadhesin, CUB domain | 0 | Direct |
BC ATP-binding domain-like | 0 | Direct |
Eps15 homology domain (EH domain) | 0 | Direct |
Nucleosome core histones | 0 | Direct |
Ubiquitin carboxyl-terminal hydrolase, UCH | 0 | Direct |
Sm motif of small nuclear ribonucleoproteins, SNRNP | 0 | Direct |
DnaQ-like 3'-5' exonuclease | 0 | Direct |
Phosphatidylinositol phosphate kinase IIbeta, PIPK IIbeta | 0 | Direct |
Third domain of FERM | 0 | Direct |
Arthropod hemocyanin, C-terminal domain | 0 | Direct |
GMC oxidoreductases | 0 | Direct |
p120GAP domain-like | 0 | Direct |
CAD domain | 0 | Direct |
Double-stranded RNA-binding domain (dsRBD) | 0 | Direct |
Single strand DNA-binding domain, SSB | 0 | Direct |
Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 | 0 | Direct |
Sec7 domain | 0 | Direct |
C-type lectin domain | 0 | Direct |
Fibrinogen C-terminal domain-like | 0 | Direct |
Astacin | 0 | Direct |
N-acetylmuramoyl-L-alanine amidase-like | 0 | Direct |
Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | Direct |
Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor | 0 | Direct |
Rel/Dorsal transcription factors, DNA-binding domain | 0 | Direct |
Kelch motif | 0 | Direct |
Tubulin, C-terminal domain | 0 | Direct |
CoA-binding domain | 0 | Direct |
6-phosphogluconate dehydrogenase-like, N-terminal domain | 0 | Direct |
SH2 domain | 0 | Direct |
Tudor domain | 0 | Direct |
LDL receptor-like module | 0 | Direct |
MBT repeat | 0 | Direct |
PAZ domain | 0 | Direct |
DNA replication initiator (cdc21/cdc54) N-terminal domain | 0 | Direct |
TBP-associated factors, TAFs | 0 | Direct |
Dual specificity phosphatase-like | 0 | Direct |
Protein prenylyltransferase | 0 | Direct |
Pancreatic carboxypeptidases | 0 | Direct |
SAM (sterile alpha motif) domain | 0 | Direct |
Cold shock DNA-binding domain-like | 0 | Direct |
Phosphotyrosine-binding domain (PTB) | 0 | Direct |
Pyk2-associated protein beta ARF-GAP domain | 0 | Direct |
Tandem AAA-ATPase domain | 0 | Direct |
First domain of FERM | 0 | Direct |
Growth factor receptor domain | 0 | Direct |
Fibronectin type III | 0 | Direct |
A DNA-binding domain in eukaryotic transcription factors | 0 | Direct |
C-terminal, gelsolin-like domain of Sec23/24 | 0 | Direct |
Hect, E3 ligase catalytic domain | 0 | Direct |
Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | Direct |
R3H domain | 0 | Direct |
Hemocyanin, N-terminal domain | 0 | Direct |
DNA polymerase III clamp loader subunits, C-terminal domain | 0 | Direct |
Multidrug efflux transporter AcrB transmembrane domain | 0 | Direct |
SCF ubiquitin ligase complex WHB domain | 0 | Direct |
Erythroid transcription factor GATA-1 | 0 | Direct |
SOCS box-like | 0 | Direct |
Choline/Carnitine O-acyltransferase | 0 | Direct |
UBA domain | 0 | Direct |
BCR-homology GTPase activation domain (BH-domain) | 0 | Direct |
Dachshund-homology domain | 0 | Direct |
RecA protein-like (ATPase-domain) | 0 | Direct |
Fibroblast growth factors (FGF) | 0 | Direct |
SNARE fusion complex | 0 | Direct |
Leukotriene A4 hydrolase N-terminal domain | 0 | Direct |
Phoshoinositide 3-kinase (PI3K), catalytic domain | 0 | Direct |
PDZ domain | 0 | Direct |
Proteasome subunits | 0 | Direct |
PX domain | 0 | Direct |
t-snare proteins | 0 | Direct |
Metal cation-transporting ATPase, ATP-binding domain N | 0 | Direct |
Thioltransferase | 0 | Direct |
BAR domain | 0 | Direct |
N-acetyl transferase, NAT | 0 | Direct |
Leukotriene A4 hydrolase catalytic domain | 0 | Direct |
Nuclear receptor ligand-binding domain | 0 | Direct |
Frizzled cysteine-rich domain | 0 | Direct |
Group II chaperonin (CCT, TRIC), intermediate domain | 0 | Direct |
SMAD MH1 domain | 0 | Direct |
Cullin homology domain | 0 | Direct |
Neurotransmitter-gated ion-channel transmembrane pore | 0 | Direct |
Serpins | 0 | Direct |
Complement control module/SCR domain | 0 | Direct |
Myotubularin-like phosphatases | 0 | Direct |
Sec1/munc18-like (SM) proteins | 0 | Direct |
Nicotinic receptor ligand binding domain-like | 0 | Direct |
UBC-related | 0 | Direct |
TSP-1 type 1 repeat | 0 | Direct |
Synaptotagmin-like (S variant) | 0 | Direct |
FYVE, a phosphatidylinositol-3-phosphate binding domain | 0 | Direct |
YWTD domain | 0 | Direct |
Class I glutamine amidotransferases (GAT) | 0 | Direct |
SPRY domain | 0 | Direct |
Ubiquitin activating enzymes (UBA) | 0 | Direct |
Regulator of G-protein signaling, RGS | 0 | Direct |
Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain | 0 | Direct |
Spectrin repeat | 0 | Direct |
HMG-box | 0 | Direct |
HLH, helix-loop-helix DNA-binding domain | 0 | Direct |
DEATH domain, DD | 0 | Direct |
VHS domain | 0 | Direct |
Forkhead DNA-binding domain | 0 | Direct |
Actin/HSP70 | 0 | Direct |
Succinyl-CoA synthetase domains | 0 | Direct |
Pyridoxal-dependent decarboxylase | 0 | Direct |
NTF2-like | 0 | Direct |
ARID domain | 0 | Direct |
Cytochrome P450 | 0 | Direct |
Clathrin coat assembly domain | 0 | Direct |
Cofilin-like | 0 | Direct |
Tropomyosin | 0 | Direct |
DBL homology domain (DH-domain) | 0 | Direct |
Ran binding protein zinc finger-like | 0 | Direct |
Class I aminoacyl-tRNA synthetases (RS), catalytic domain | 0 | Direct |
Toll/Interleukin receptor TIR domain | 0 | Direct |
Cadherin | 0 | Direct |
Tyrosine-dependent oxidoreductases | 0 | Direct |
Protein kinases, catalytic subunit | 0 | Direct |
SMAD domain | 0 | Direct |
Class II glutamine amidotransferases | 0 | Direct |
Acetylcholinesterase-like | 0 | Direct |
Pleckstrin-homology domain (PH domain) | 0 | Direct |
LIM domain | 0 | Direct |
ZZ domain | 0 | Direct |
PLC-like (P variant) | 0 | Direct |
Regulator of chromosome condensation RCC1 | 0 | Direct |
Diacylglycerol kinase-like | 0 | Direct |
Extended AAA-ATPase domain | 0 | Direct |
NF-kappa-B/REL/DORSAL transcription factors, C-terminal domain | 0 | Direct |
SH3-domain | 0 | Direct |
Diap1 N-terninal region-like | 0 | Direct |
Calcium ATPase, transduction domain A | 0 | Direct |
Plexin repeat | 0 | Direct |
Pointed domain | 0 | Direct |
BTB/POZ domain | 0 | Direct |
B-box zinc-binding domain | 0 | Direct |
ALDH-like | 0 | Direct |
Neutral endopeptidase (neprilysin) | 0 | Direct |
Inositol polyphosphate 5-phosphatase (IPP5) | 0 | Direct |
Platelet-derived growth factor-like | 0 | Direct |
Extracellular domain of cell surface receptors | 0 | Direct |
BC N-terminal domain-like | 0 | Direct |
Histone deacetylase, HDAC | 0 | Direct |
Transforming growth factor (TGF)-beta | 0 | Direct |
EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | Direct |
Sema domain | 0 | Direct |
Hairy Orange domain | 0 | Direct |
FtsH protease domain-like | 0 | Direct |
L27 domain | 0 | Direct |
EF-hand modules in multidomain proteins | 0 | Direct |
Elongation factors | 0 | Direct |
WW domain | 0 | Direct |
Cysteine-rich DNA binding domain, (DM domain) | 0 | Direct |
Laminin-type module | 0 | Direct |
POU-specific domain | 0 | Direct |
Tetramerization domain of potassium channels | 0 | Direct |
Armadillo repeat | 0 | Direct |
Tetratricopeptide repeat (TPR) | 0 | Direct |
Mob1/phocein | 0 | Direct |
Rhomboid-like | 0 | Direct |
Chromo barrel domain | 0 | Direct |
Smc hinge domain | 0 | Direct |
CCCH zinc finger | 0 | Direct |
CBS-domain pair | 0 | Direct |
Transcriptional factor domain | 0 | Direct |
FAD-linked reductases, N-terminal domain | 0 | Direct |
SAP domain | 0 | Direct |
L-arabinose binding protein-like | 0 | Direct |
Canonical RBD | 0 | Direct |
Integrin domains | 0 | Direct |
Bromodomain | 0 | Direct |
T-box | 0 | Direct |
Pepsin-like | 0 | Direct |
I set domains | 0 | Direct |
CRAL/TRIO domain | 0 | Direct |
FKBP immunophilin/proline isomerase | 0 | Direct |
Hypoxia-inducible factor Hif2a, C-terminal domain | 0 | Direct |
Cell cycle control phosphatase, catalytic domain | 0 | Direct |
Group II chaperonin (CCT, TRIC), ATPase domain | 0 | Direct |
Ras-binding domain, RBD | 0 | Direct |
Group II chaperonin (CCT, TRIC), apical domain | 0 | Direct |
Phosphate binding protein-like | 0 | Direct |
2Fe-2S ferredoxin domains from multidomain proteins | 0 | Direct |
Zf-UBP | 0 | Direct |
F-box domain | 0 | Direct |
Cullin repeat | 0 | Direct |
PDEase | 0 | Direct |
PIWI domain | 0 | Direct |
acyl-CoA oxidase C-terminal domains | 0 | Direct |
Mitochondrial carrier | 0 | Direct |
PHD domain | 0 | Direct |
cAMP-binding domain | 0 | Direct |
Discoidin domain (FA58C, coagulation factor 5/8 C-terminal domain) | 0 | Direct |
Nucleotide and nucleoside kinases | 0 | Direct |
Protein serine/threonine phosphatase | 0 | Direct |
Second domain of FERM | 0 | Direct |
Formin homology 2 domain (FH2 domain) | 0 | Direct |
Retrovirus zinc finger-like domains | 0 | Direct |
Arrestin/Vps26-like | 0 | Direct |
Ubiquitin carboxyl-terminal hydrolase UCH-L | 0 | Direct |
Phoshoinositide 3-kinase (PI3K) helical domain | 0 | Direct |
TATA-box binding protein (TBP), C-terminal domain | 0 | Direct |
Histone lysine methyltransferases | 0 | Direct |
acyl-CoA oxidase N-terminal domains | 0 | Direct |
La domain | 0 | Direct |
THAP domain | 0 | Direct |
Motor proteins | 0 | Direct |
Nuclear receptor | 0 | Direct |
Homeodomain | 0 | Direct |
Chromo domain | 0 | Direct |
Calponin-homology domain, CH-domain | 0 | Direct |
MIR domain | 0 | Direct |
Clathrin adaptor core protein | 0 | Direct |
G proteins | 0.4069 | Inherited |
Classic zinc finger, C2H2 | 0.4254 | Inherited |
Ankyrin repeat | 0.5553 | Inherited |
Leucine zipper domain | 0.8518 | Inherited |
Ubiquitin-related | 0.8789 | Inherited |
Cyclin | 0.8931 | Inherited |
Tubulin, GTPase domain | 0.922 | Inherited |
Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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A presence/absence matrix is generated using protein domain
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]
Supra-domain (including individual superfamily)
(show details)
Supra-domains annotated to this FA term (Not in SPFA)
Highlighted in gray are those with FDR>0.001
Supra-domain (Single) |
FDR (all) |
Annotation (direct or inherited) |
Transducin (alpha subunit), insertion domain | 0 | DIRECT |
Multidrug resistance efflux transporter EmrE | 0 | DIRECT |
Multidrug efflux transporter AcrB transmembrane domain | 0 | DIRECT |
DBL homology domain (DH-domain) | 0 | DIRECT |
Succinyl-CoA synthetase domains | 0 | DIRECT |
C-terminal, gelsolin-like domain of Sec23/24 | 0 | DIRECT |
S15/NS1 RNA-binding domain | 0 | DIRECT |
dsRNA-binding domain-like | 0 | DIRECT |
Metal cation-transporting ATPase, ATP-binding domain N | 0 | DIRECT |
Retrovirus zinc finger-like domains | 0 | DIRECT |
Growth factor receptor domain | 0 | DIRECT |
FtsH protease domain-like | 0 | DIRECT |
UDP-Glycosyltransferase/glycogen phosphorylase | 0 | DIRECT |
4Fe-4S ferredoxins | 0 | DIRECT |
Smc hinge domain | 0 | DIRECT |
SMAD MH1 domain | 0 | DIRECT |
PDZ domain-like | 0 | DIRECT |
SPOC domain-like | 0 | DIRECT |
ENTH/VHS domain | 0 | DIRECT |
DNase I-like | 0 | DIRECT |
Nicotinic receptor ligand binding domain-like | 0 | DIRECT |
Metalloproteases ("zincins"), catalytic domain | 0 | DIRECT |
Cytochrome P450 | 0 | DIRECT |
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0 | DIRECT |
Leukotriene A4 hydrolase N-terminal domain | 0 | DIRECT |
GTPase activation domain, GAP | 0 | DIRECT |
Sec1/munc18-like (SM) proteins | 0 | DIRECT |
NTF2-like | 0 | DIRECT |
Cytokine | 0 | DIRECT |
PX domain | 0 | DIRECT |
Acid phosphatase/Vanadium-dependent haloperoxidase | 0 | DIRECT |
Periplasmic binding protein-like II | 0 | DIRECT |
HD-domain/PDEase-like | 0 | DIRECT |
SH2 domain | 0 | DIRECT |
Spectrin repeat | 0 | DIRECT |
SNARE-like | 0 | DIRECT |
GINS helical bundle-like | 0 | DIRECT |
HMG-box | 0 | DIRECT |
ARID-like | 0 | DIRECT |
Concanavalin A-like lectins/glucanases | 0 | DIRECT |
MIR domain | 0 | DIRECT |
Sm-like ribonucleoproteins | 0 | DIRECT |
SET domain | 0 | DIRECT |
NAD kinase/diacylglycerol kinase-like | 0 | DIRECT |
Calponin-homology domain, CH-domain | 0 | DIRECT |
Mitochondrial carrier | 0 | DIRECT |
Cadherin-like | 0 | DIRECT |
DNA/RNA polymerases | 0 | DIRECT |
SIS domain | 0 | DIRECT |
PIN domain-like | 0 | DIRECT |
EF-hand | 0 | DIRECT |
Glycerol-3-phosphate (1)-acyltransferase | 0 | DIRECT |
Plexin repeat | 0 | DIRECT |
HSP20-like chaperones | 0 | DIRECT |
Cysteine-rich DNA binding domain, (DM domain) | 0 | DIRECT |
SNF-like | 0 | DIRECT |
Histone-fold | 0 | DIRECT |
Zinc beta-ribbon | 0 | DIRECT |
Hemocyanin, N-terminal domain | 0 | DIRECT |
Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain | 0 | DIRECT |
6-phosphogluconate dehydrogenase C-terminal domain-like | 0 | DIRECT |
Tropomyosin | 0 | DIRECT |
Riboflavin synthase domain-like | 0 | DIRECT |
Orange domain-like | 0 | DIRECT |
Rhodanese/Cell cycle control phosphatase | 0 | DIRECT |
SNARE fusion complex | 0 | DIRECT |
Glucocorticoid receptor-like (DNA-binding domain) | 0 | DIRECT |
Kazal-type serine protease inhibitors | 0 | DIRECT |
Terpenoid synthases | 0 | DIRECT |
SAP domain | 0 | DIRECT |
(Phosphotyrosine protein) phosphatases II | 0 | DIRECT |
Glutamine synthetase/guanido kinase | 0 | DIRECT |
Spermadhesin, CUB domain | 0 | DIRECT |
Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | DIRECT |
NHL repeat | 0 | DIRECT |
Clathrin adaptor appendage domain | 0 | DIRECT |
"Winged helix" DNA-binding domain | 0 | DIRECT |
Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 | 0 | DIRECT |
PapD-like | 0 | DIRECT |
Regulator of G-protein signaling, RGS | 0 | DIRECT |
alpha-catenin/vinculin-like | 0 | DIRECT |
EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | DIRECT |
N-terminal nucleophile aminohydrolases (Ntn hydrolases) | 0 | DIRECT |
FYVE/PHD zinc finger | 0 | DIRECT |
Nucleic acid-binding proteins | 0 | DIRECT |
Activating enzymes of the ubiquitin-like proteins | 0 | DIRECT |
Neurotransmitter-gated ion-channel transmembrane pore | 0 | DIRECT |
TSP-1 type 1 repeat | 0 | DIRECT |
BAR/IMD domain-like | 0 | DIRECT |
Acyl-CoA N-acyltransferases (Nat) | 0 | DIRECT |
RCC1/BLIP-II | 0 | DIRECT |
Tudor/PWWP/MBT | 0 | DIRECT |
Complement control module/SCR domain | 0 | DIRECT |
Calcium ATPase, transmembrane domain M | 0 | DIRECT |
Arginase/deacetylase | 0 | DIRECT |
L30e-like | 0 | DIRECT |
FAD/NAD(P)-binding domain | 0 | DIRECT |
CBS-domain pair | 0 | DIRECT |
Zn-dependent exopeptidases | 0 | DIRECT |
Calcium ATPase, transduction domain A | 0 | DIRECT |
RNA-binding domain, RBD | 0 | DIRECT |
GroEL-intermediate domain like | 0 | DIRECT |
PH domain-like | 0 | DIRECT |
Actin-like ATPase domain | 0 | DIRECT |
Serpins | 0 | DIRECT |
HIT/MYND zinc finger-like | 0 | DIRECT |
PAZ domain | 0 | DIRECT |
Frizzled cysteine-rich domain | 0 | DIRECT |
C2 domain (Calcium/lipid-binding domain, CaLB) | 0 | DIRECT |
E set domains | 0 | DIRECT |
Acyl-CoA dehydrogenase C-terminal domain-like | 0 | DIRECT |
A DNA-binding domain in eukaryotic transcription factors | 0 | DIRECT |
Tubulin C-terminal domain-like | 0 | DIRECT |
F-box domain | 0 | DIRECT |
Cysteine proteinases | 0 | DIRECT |
LDL receptor-like module | 0 | DIRECT |
Cysteine-rich domain | 0 | DIRECT |
Acyl-CoA dehydrogenase NM domain-like | 0 | DIRECT |
post-AAA+ oligomerization domain-like | 0 | DIRECT |
Phosphoglycerate mutase-like | 0 | DIRECT |
Macro domain-like | 0 | DIRECT |
Putative DNA-binding domain | 0 | DIRECT |
Thiamin diphosphate-binding fold (THDP-binding) | 0 | DIRECT |
L domain-like | 0 | DIRECT |
GroEL equatorial domain-like | 0 | DIRECT |
Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | DIRECT |
Ribosomal protein S5 domain 2-like | 0 | DIRECT |
Ferredoxin reductase-like, C-terminal NADP-linked domain | 0 | DIRECT |
Galactose-binding domain-like | 0 | DIRECT |
Periplasmic binding protein-like I | 0 | DIRECT |
TIMP-like | 0 | DIRECT |
YVTN repeat-like/Quinoprotein amine dehydrogenase | 0 | DIRECT |
DEATH domain | 0 | DIRECT |
Protein prenylyltransferase | 0 | DIRECT |
Quinoprotein alcohol dehydrogenase-like | 0 | DIRECT |
Cullin homology domain | 0 | DIRECT |
Alkaline phosphatase-like | 0 | DIRECT |
Rhomboid-like | 0 | DIRECT |
RNase III domain-like | 0 | DIRECT |
UBC-like | 0 | DIRECT |
TATA-box binding protein-like | 0 | DIRECT |
BRCT domain | 0 | DIRECT |
CRAL/TRIO domain | 0 | DIRECT |
CCCH zinc finger | 0 | DIRECT |
Nuclear receptor ligand-binding domain | 0 | DIRECT |
Translation proteins SH3-like domain | 0 | DIRECT |
ALDH-like | 0 | DIRECT |
Immunoglobulin | 0 | DIRECT |
Nucleotide-diphospho-sugar transferases | 0 | DIRECT |
Hect, E3 ligase catalytic domain | 0 | DIRECT |
vWA-like | 0 | DIRECT |
cAMP-binding domain-like | 0 | DIRECT |
Clavaminate synthase-like | 0 | DIRECT |
Ferritin-like | 0 | DIRECT |
HAD-like | 0 | DIRECT |
FAD-linked reductases, C-terminal domain | 0 | DIRECT |
Cystine-knot cytokines | 0 | DIRECT |
ACP-like | 0 | DIRECT |
FabD/lysophospholipase-like | 0 | DIRECT |
Snake toxin-like | 0 | DIRECT |
Supernatant protein factor (SPF), C-terminal domain | 0 | DIRECT |
Cullin repeat-like | 0 | DIRECT |
2Fe-2S ferredoxin-like | 0 | DIRECT |
Adenine nucleotide alpha hydrolases-like | 0 | DIRECT |
Nucleotidylyl transferase | 0 | DIRECT |
EGF/Laminin | 0 | DIRECT |
Tetraspanin | 0 | DIRECT |
Cap-Gly domain | 0 | DIRECT |
Chromo domain-like | 0 | DIRECT |
PriA/YqbF domain | 0 | DIRECT |
L27 domain | 0 | DIRECT |
Caspase-like | 0 | DIRECT |
PYP-like sensor domain (PAS domain) | 0 | DIRECT |
Sema domain | 0 | DIRECT |
FnI-like domain | 0 | DIRECT |
Sec7 domain | 0 | DIRECT |
SMAD/FHA domain | 0 | DIRECT |
TRAF domain-like | 0 | DIRECT |
Bromodomain | 0 | DIRECT |
GroEL apical domain-like | 0 | DIRECT |
ArfGap/RecO-like zinc finger | 0 | DIRECT |
B-box zinc-binding domain | 0 | DIRECT |
p53-like transcription factors | 0 | DIRECT |
Kelch motif | 0 | DIRECT |
Formin homology 2 domain (FH2 domain) | 0 | DIRECT |
SAICAR synthase-like | 0 | DIRECT |
SOCS box-like | 0 | DIRECT |
MFS general substrate transporter | 0 | DIRECT |
t-snare proteins | 0 | DIRECT |
SH3-domain | 0 | DIRECT |
DNA-binding domain | 0 | DIRECT |
PreATP-grasp domain | 0 | DIRECT |
Toll/Interleukin receptor TIR domain | 0 | DIRECT |
(Trans)glycosidases | 0 | DIRECT |
R3H domain | 0 | DIRECT |
Fibronectin type III | 0 | DIRECT |
Glutathione synthetase ATP-binding domain-like | 0 | DIRECT |
Ypt/Rab-GAP domain of gyp1p | 0 | DIRECT |
FKBP-like | 0 | DIRECT |
Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor | 0 | DIRECT |
PAP/OAS1 substrate-binding domain | 0 | DIRECT |
Metallo-dependent phosphatases | 0 | DIRECT |
YWTD domain | 0 | DIRECT |
Ribonuclease H-like | 0 | DIRECT |
CAD & PB1 domains | 0 | DIRECT |
SAM/Pointed domain | 0 | DIRECT |
beta-sandwich domain of Sec23/24 | 0 | DIRECT |
TPR-like | 0 | DIRECT |
Actin depolymerizing proteins | 0 | DIRECT |
Ran binding protein zinc finger-like | 0 | DIRECT |
lambda repressor-like DNA-binding domains | 0 | DIRECT |
N-acetylmuramoyl-L-alanine amidase-like | 0 | DIRECT |
C-type lectin-like | 0 | DIRECT |
Protease propeptides/inhibitors | 0 | DIRECT |
Mob1/phocein | 0 | DIRECT |
Second domain of FERM | 0 | DIRECT |
Class I glutamine amidotransferase-like | 0 | DIRECT |
Integrin domains | 0 | DIRECT |
HLH, helix-loop-helix DNA-binding domain | 0 | DIRECT |
WW domain | 0 | DIRECT |
SAND domain-like | 0 | DIRECT |
RNI-like | 0 | DIRECT |
Fibrinogen C-terminal domain-like | 0 | DIRECT |
Protein kinase-like (PK-like) | 0.09281 | INHERITED FROM: embryonic/larval integumentary system || egg || embryo || ovariole || nervous system || organism subdivision || photoreceptor cell R8 of pale ommatidium || gut epithelial section || pupa || organ system subdivision || portion of tissue || female-specific anatomical entity || imaginal disc || pupal/adult digestive system || synaptic neuropil || somatic cell of ovariole || intestinal stem cell || larval imaginal tissue |
beta-beta-alpha zinc fingers | 0.136 | INHERITED FROM: region of integument || segment || adult integumentary system || adult thoracic segment || appendage || serotonergic neuron || subesophageal ganglion neuron || thorax || adult thorax || organism subdivision || organ system || organ system subdivision || adult tagma || integumentary system || adult || adult mesothoracic segment || tagma || adult segment || thoracic segment |
Homeodomain-like | 0.4807 | INHERITED FROM: alula || maxillary palpus || adult antennal segment || terminal filament || embryonic segment || adult metathoracic segment || EL neuron || U neuron || antennal segment || region of integument || denticle belt || gonadal sheath proper primordium || embryonic/larval subesophageal ganglion || uniglomerular antennal lobe projection neuron || adult external head || A1-7 ventral acute muscle 1 || stomatogastric nervous system || embryonic/larval thoracic/abdominal lateral sensory cluster || ventral nervous system || prothoracic ventral intersegmental muscle || segment || embryonic neuroblast || embryonic thoracic segment || metathoracic segment || eo-type sensillum || central brain || dorsal margin ommatidium || ventral nerve cord primordium || adult integumentary system || embryonic/larval sensillum || appendage || extended germ band embryo || mouthpart || T1 beard || thoracic neuroblast || tritocerebrum || dorsal metathorax || neuron projection bundle || embryonic mesothoracic segment || developing embryonic structure || embryonic/larval neuron || embryonic head segment || parasegment || larval metathoracic segment || embryonic/larval sense organ || thorax || dorsal rim area || abdominal segment || adult thorax || presumptive embryonic/larval nervous system || embryonic/larval dorsal vessel || embryonic thorax || integumentary process || organism subdivision || larval prothoracic segment || larval tagma || larval segment || presumptive embryonic/larval central nervous system || larval abdomen || embryonic supraesophageal neuromere || sense organ || segment of leg || metathoracic ventral denticle belt || embryonic protocerebrum || larval neuromere || head capsule || ganglion || embryonic/larval muscle system || organ system || abdomen || embryonic/larval labial organ || distiproboscis || hypodermal muscle of prothorax || aorta primordium || embryonic/larval digestive system || embryonic tagma || organ system subdivision || dorsal margin photoreceptor || adult abdomen || gland || antennal lobe glomerulus VA1v || mesothoracic tibial apical bristle || embryonic fiber tract founder cluster || mesothoracic tergum || adult external metathorax || appendage segment || commissure || interneuron || basiproboscis || antenna || cell cluster organ || head segment || pretarsus || integumentary system || sclerite || trunk mesoderm derivative || gnathal segment || adult || transverse nerve || proboscis || female terminalia || embryonic head || tract neuropil || wing hinge || embryonic/larval supraesophageal ganglion || multi-tissue structure || embryonic brain || integument of larval mesothoracic segment || intercalary segment || tagma || muscle cell || head bristle || larval abdominal segment || adult segment |
RING/U-box | 0.4835 | INHERITED FROM: garland cell || embryonic/larval garland organ || embryonic/larval garland cell |
Ankyrin repeat | 0.556 | INHERITED FROM: Johnston organ neuron |
POZ domain | 0.642 | INHERITED FROM: terminal filament |
P-loop containing nucleoside triphosphate hydrolases | 0.6675 | INHERITED FROM: gonad || germline cyst || reproductive system |
Cyclin-like | 0.8397 | INHERITED FROM: morphogenetic furrow |
Leucine zipper domain | 0.853 | INHERITED FROM: adult dorsal vessel || embryonic dorsal epidermis || adult heart |
Tubulin nucleotide-binding domain-like | 0.9244 | INHERITED FROM: spermatid cyst || spermatid || fat cell |
Invertebrate chitin-binding proteins | 0.939 | INHERITED FROM: embryonic/larval integumentary system || embryonic/larval cuticle || embryonic/larval dorsal trunk || embryonic/larval trachea || tracheal system || embryonic/larval tracheal system || primary trachea |
CoA-dependent acyltransferases | 0.9533 | INHERITED FROM: skeletal muscle of mesothorax || skeletal muscle of thorax || adult somatic muscle || flight muscle || adult muscle system |
Supra-domain (Single) |
FDR (all) |
Annotation (direct or inherited) |
Transducin (alpha subunit), insertion domain | 0 | Direct |
Multidrug resistance efflux transporter EmrE | 0 | Direct |
Multidrug efflux transporter AcrB transmembrane domain | 0 | Direct |
DBL homology domain (DH-domain) | 0 | Direct |
Succinyl-CoA synthetase domains | 0 | Direct |
C-terminal, gelsolin-like domain of Sec23/24 | 0 | Direct |
S15/NS1 RNA-binding domain | 0 | Direct |
dsRNA-binding domain-like | 0 | Direct |
Metal cation-transporting ATPase, ATP-binding domain N | 0 | Direct |
Retrovirus zinc finger-like domains | 0 | Direct |
Growth factor receptor domain | 0 | Direct |
FtsH protease domain-like | 0 | Direct |
UDP-Glycosyltransferase/glycogen phosphorylase | 0 | Direct |
4Fe-4S ferredoxins | 0 | Direct |
Smc hinge domain | 0 | Direct |
SMAD MH1 domain | 0 | Direct |
PDZ domain-like | 0 | Direct |
SPOC domain-like | 0 | Direct |
ENTH/VHS domain | 0 | Direct |
DNase I-like | 0 | Direct |
Nicotinic receptor ligand binding domain-like | 0 | Direct |
Metalloproteases ("zincins"), catalytic domain | 0 | Direct |
Cytochrome P450 | 0 | Direct |
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0 | Direct |
Leukotriene A4 hydrolase N-terminal domain | 0 | Direct |
GTPase activation domain, GAP | 0 | Direct |
Sec1/munc18-like (SM) proteins | 0 | Direct |
NTF2-like | 0 | Direct |
Cytokine | 0 | Direct |
PX domain | 0 | Direct |
Acid phosphatase/Vanadium-dependent haloperoxidase | 0 | Direct |
Periplasmic binding protein-like II | 0 | Direct |
HD-domain/PDEase-like | 0 | Direct |
SH2 domain | 0 | Direct |
Spectrin repeat | 0 | Direct |
SNARE-like | 0 | Direct |
GINS helical bundle-like | 0 | Direct |
HMG-box | 0 | Direct |
ARID-like | 0 | Direct |
Concanavalin A-like lectins/glucanases | 0 | Direct |
MIR domain | 0 | Direct |
Sm-like ribonucleoproteins | 0 | Direct |
SET domain | 0 | Direct |
NAD kinase/diacylglycerol kinase-like | 0 | Direct |
Calponin-homology domain, CH-domain | 0 | Direct |
Mitochondrial carrier | 0 | Direct |
Cadherin-like | 0 | Direct |
DNA/RNA polymerases | 0 | Direct |
SIS domain | 0 | Direct |
PIN domain-like | 0 | Direct |
EF-hand | 0 | Direct |
Glycerol-3-phosphate (1)-acyltransferase | 0 | Direct |
Plexin repeat | 0 | Direct |
HSP20-like chaperones | 0 | Direct |
Cysteine-rich DNA binding domain, (DM domain) | 0 | Direct |
SNF-like | 0 | Direct |
Histone-fold | 0 | Direct |
Zinc beta-ribbon | 0 | Direct |
Hemocyanin, N-terminal domain | 0 | Direct |
Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain | 0 | Direct |
6-phosphogluconate dehydrogenase C-terminal domain-like | 0 | Direct |
Tropomyosin | 0 | Direct |
Riboflavin synthase domain-like | 0 | Direct |
Orange domain-like | 0 | Direct |
Rhodanese/Cell cycle control phosphatase | 0 | Direct |
SNARE fusion complex | 0 | Direct |
Glucocorticoid receptor-like (DNA-binding domain) | 0 | Direct |
Kazal-type serine protease inhibitors | 0 | Direct |
Terpenoid synthases | 0 | Direct |
SAP domain | 0 | Direct |
(Phosphotyrosine protein) phosphatases II | 0 | Direct |
Glutamine synthetase/guanido kinase | 0 | Direct |
Spermadhesin, CUB domain | 0 | Direct |
Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | Direct |
NHL repeat | 0 | Direct |
Clathrin adaptor appendage domain | 0 | Direct |
"Winged helix" DNA-binding domain | 0 | Direct |
Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 | 0 | Direct |
PapD-like | 0 | Direct |
Regulator of G-protein signaling, RGS | 0 | Direct |
alpha-catenin/vinculin-like | 0 | Direct |
EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | Direct |
N-terminal nucleophile aminohydrolases (Ntn hydrolases) | 0 | Direct |
FYVE/PHD zinc finger | 0 | Direct |
Nucleic acid-binding proteins | 0 | Direct |
Activating enzymes of the ubiquitin-like proteins | 0 | Direct |
Neurotransmitter-gated ion-channel transmembrane pore | 0 | Direct |
TSP-1 type 1 repeat | 0 | Direct |
BAR/IMD domain-like | 0 | Direct |
Acyl-CoA N-acyltransferases (Nat) | 0 | Direct |
RCC1/BLIP-II | 0 | Direct |
Tudor/PWWP/MBT | 0 | Direct |
Complement control module/SCR domain | 0 | Direct |
Calcium ATPase, transmembrane domain M | 0 | Direct |
Arginase/deacetylase | 0 | Direct |
L30e-like | 0 | Direct |
FAD/NAD(P)-binding domain | 0 | Direct |
CBS-domain pair | 0 | Direct |
Zn-dependent exopeptidases | 0 | Direct |
Calcium ATPase, transduction domain A | 0 | Direct |
RNA-binding domain, RBD | 0 | Direct |
GroEL-intermediate domain like | 0 | Direct |
PH domain-like | 0 | Direct |
Actin-like ATPase domain | 0 | Direct |
Serpins | 0 | Direct |
HIT/MYND zinc finger-like | 0 | Direct |
PAZ domain | 0 | Direct |
Frizzled cysteine-rich domain | 0 | Direct |
C2 domain (Calcium/lipid-binding domain, CaLB) | 0 | Direct |
E set domains | 0 | Direct |
Acyl-CoA dehydrogenase C-terminal domain-like | 0 | Direct |
A DNA-binding domain in eukaryotic transcription factors | 0 | Direct |
Tubulin C-terminal domain-like | 0 | Direct |
F-box domain | 0 | Direct |
Cysteine proteinases | 0 | Direct |
LDL receptor-like module | 0 | Direct |
Cysteine-rich domain | 0 | Direct |
Acyl-CoA dehydrogenase NM domain-like | 0 | Direct |
post-AAA+ oligomerization domain-like | 0 | Direct |
Phosphoglycerate mutase-like | 0 | Direct |
Macro domain-like | 0 | Direct |
Putative DNA-binding domain | 0 | Direct |
Thiamin diphosphate-binding fold (THDP-binding) | 0 | Direct |
L domain-like | 0 | Direct |
GroEL equatorial domain-like | 0 | Direct |
Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | Direct |
Ribosomal protein S5 domain 2-like | 0 | Direct |
Ferredoxin reductase-like, C-terminal NADP-linked domain | 0 | Direct |
Galactose-binding domain-like | 0 | Direct |
Periplasmic binding protein-like I | 0 | Direct |
TIMP-like | 0 | Direct |
YVTN repeat-like/Quinoprotein amine dehydrogenase | 0 | Direct |
DEATH domain | 0 | Direct |
Protein prenylyltransferase | 0 | Direct |
Quinoprotein alcohol dehydrogenase-like | 0 | Direct |
Cullin homology domain | 0 | Direct |
Alkaline phosphatase-like | 0 | Direct |
Rhomboid-like | 0 | Direct |
RNase III domain-like | 0 | Direct |
UBC-like | 0 | Direct |
TATA-box binding protein-like | 0 | Direct |
BRCT domain | 0 | Direct |
CRAL/TRIO domain | 0 | Direct |
CCCH zinc finger | 0 | Direct |
Nuclear receptor ligand-binding domain | 0 | Direct |
Translation proteins SH3-like domain | 0 | Direct |
ALDH-like | 0 | Direct |
Immunoglobulin | 0 | Direct |
Nucleotide-diphospho-sugar transferases | 0 | Direct |
Hect, E3 ligase catalytic domain | 0 | Direct |
vWA-like | 0 | Direct |
cAMP-binding domain-like | 0 | Direct |
Clavaminate synthase-like | 0 | Direct |
Ferritin-like | 0 | Direct |
HAD-like | 0 | Direct |
FAD-linked reductases, C-terminal domain | 0 | Direct |
Cystine-knot cytokines | 0 | Direct |
ACP-like | 0 | Direct |
FabD/lysophospholipase-like | 0 | Direct |
Snake toxin-like | 0 | Direct |
Supernatant protein factor (SPF), C-terminal domain | 0 | Direct |
Cullin repeat-like | 0 | Direct |
2Fe-2S ferredoxin-like | 0 | Direct |
Adenine nucleotide alpha hydrolases-like | 0 | Direct |
Nucleotidylyl transferase | 0 | Direct |
EGF/Laminin | 0 | Direct |
Tetraspanin | 0 | Direct |
Cap-Gly domain | 0 | Direct |
Chromo domain-like | 0 | Direct |
PriA/YqbF domain | 0 | Direct |
L27 domain | 0 | Direct |
Caspase-like | 0 | Direct |
PYP-like sensor domain (PAS domain) | 0 | Direct |
Sema domain | 0 | Direct |
FnI-like domain | 0 | Direct |
Sec7 domain | 0 | Direct |
SMAD/FHA domain | 0 | Direct |
TRAF domain-like | 0 | Direct |
Bromodomain | 0 | Direct |
GroEL apical domain-like | 0 | Direct |
ArfGap/RecO-like zinc finger | 0 | Direct |
B-box zinc-binding domain | 0 | Direct |
p53-like transcription factors | 0 | Direct |
Kelch motif | 0 | Direct |
Formin homology 2 domain (FH2 domain) | 0 | Direct |
SAICAR synthase-like | 0 | Direct |
SOCS box-like | 0 | Direct |
MFS general substrate transporter | 0 | Direct |
t-snare proteins | 0 | Direct |
SH3-domain | 0 | Direct |
DNA-binding domain | 0 | Direct |
PreATP-grasp domain | 0 | Direct |
Toll/Interleukin receptor TIR domain | 0 | Direct |
(Trans)glycosidases | 0 | Direct |
R3H domain | 0 | Direct |
Fibronectin type III | 0 | Direct |
Glutathione synthetase ATP-binding domain-like | 0 | Direct |
Ypt/Rab-GAP domain of gyp1p | 0 | Direct |
FKBP-like | 0 | Direct |
Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor | 0 | Direct |
PAP/OAS1 substrate-binding domain | 0 | Direct |
Metallo-dependent phosphatases | 0 | Direct |
YWTD domain | 0 | Direct |
Ribonuclease H-like | 0 | Direct |
CAD & PB1 domains | 0 | Direct |
SAM/Pointed domain | 0 | Direct |
beta-sandwich domain of Sec23/24 | 0 | Direct |
TPR-like | 0 | Direct |
Actin depolymerizing proteins | 0 | Direct |
Ran binding protein zinc finger-like | 0 | Direct |
lambda repressor-like DNA-binding domains | 0 | Direct |
N-acetylmuramoyl-L-alanine amidase-like | 0 | Direct |
C-type lectin-like | 0 | Direct |
Protease propeptides/inhibitors | 0 | Direct |
Mob1/phocein | 0 | Direct |
Second domain of FERM | 0 | Direct |
Class I glutamine amidotransferase-like | 0 | Direct |
Integrin domains | 0 | Direct |
HLH, helix-loop-helix DNA-binding domain | 0 | Direct |
WW domain | 0 | Direct |
SAND domain-like | 0 | Direct |
RNI-like | 0 | Direct |
Fibrinogen C-terminal domain-like | 0 | Direct |
Protein kinase-like (PK-like) | 0.09281 | Inherited |
beta-beta-alpha zinc fingers | 0.136 | Inherited |
Homeodomain-like | 0.4807 | Inherited |
RING/U-box | 0.4835 | Inherited |
Ankyrin repeat | 0.556 | Inherited |
POZ domain | 0.642 | Inherited |
P-loop containing nucleoside triphosphate hydrolases | 0.6675 | Inherited |
Cyclin-like | 0.8397 | Inherited |
Leucine zipper domain | 0.853 | Inherited |
Tubulin nucleotide-binding domain-like | 0.9244 | Inherited |
Invertebrate chitin-binding proteins | 0.939 | Inherited |
CoA-dependent acyltransferases | 0.9533 | Inherited |
(show details)
Supra-domains annotated to this FA term (Not in SPFA)
Highlighted in gray are those with FDR>0.001
Supra-domain (Duplex) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
57716,46689 57716 - Glucocorticoid receptor-like (DNA-binding domain) 46689 - Homeodomain-like | 0 | DIRECT |
101912,103575 101912 - Sema domain 103575 - Plexin repeat | 0 | DIRECT |
57196,49899 57196 - EGF/Laminin 49899 - Concanavalin A-like lectins/glucanases | 0 | DIRECT |
49313,49313 49313 - Cadherin-like 49313 - Cadherin-like | 0 | DIRECT |
52540,140990 52540 - P-loop containing nucleoside triphosphate hydrolases 140990 - FtsH protease domain-like | 0 | DIRECT |
47769,47769 47769 - SAM/Pointed domain 47769 - SAM/Pointed domain | 0 | DIRECT |
57903,47370 57903 - FYVE/PHD zinc finger 47370 - Bromodomain | 0 | DIRECT |
46966,46966 46966 - Spectrin repeat 46966 - Spectrin repeat | 0 | DIRECT |
55550,158235 55550 - SH2 domain 158235 - SOCS box-like | 0 | DIRECT |
57535,57535 57535 - Complement control module/SCR domain 57535 - Complement control module/SCR domain | 0 | DIRECT |
52799,52799 52799 - (Phosphotyrosine protein) phosphatases II 52799 - (Phosphotyrosine protein) phosphatases II | 0 | DIRECT |
52058,48726 52058 - L domain-like 48726 - Immunoglobulin | 0 | DIRECT |
101690,53098 101690 - PAZ domain 53098 - Ribonuclease H-like | 0 | DIRECT |
56645,47203 56645 - Acyl-CoA dehydrogenase NM domain-like 47203 - Acyl-CoA dehydrogenase C-terminal domain-like | 0 | DIRECT |
49562,49562 49562 - C2 domain (Calcium/lipid-binding domain, CaLB) 49562 - C2 domain (Calcium/lipid-binding domain, CaLB) | 0 | DIRECT |
57196,57184 57196 - EGF/Laminin 57184 - Growth factor receptor domain | 0 | DIRECT |
49417,81296 49417 - p53-like transcription factors 81296 - E set domains | 0 | DIRECT |
48403,48403 48403 - Ankyrin repeat 48403 - Ankyrin repeat | 0 | DIRECT |
50044,52540 50044 - SH3-domain 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
53067,53067 53067 - Actin-like ATPase domain 53067 - Actin-like ATPase domain | 0 | DIRECT |
55550,56112 55550 - SH2 domain 56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
52833,52833 52833 - Thioredoxin-like 52833 - Thioredoxin-like | 0 | DIRECT |
54236,47031 54236 - Ubiquitin-like 47031 - Second domain of FERM | 0 | DIRECT |
57184,57184 57184 - Growth factor receptor domain 57184 - Growth factor receptor domain | 0 | DIRECT |
52777,52777 52777 - CoA-dependent acyltransferases 52777 - CoA-dependent acyltransferases | 0 | DIRECT |
57889,57889 57889 - Cysteine-rich domain 57889 - Cysteine-rich domain | 0 | DIRECT |
51905,54373 51905 - FAD/NAD(P)-binding domain 54373 - FAD-linked reductases, C-terminal domain | 0 | DIRECT |
63712,90112 63712 - Nicotinic receptor ligand binding domain-like 90112 - Neurotransmitter-gated ion-channel transmembrane pore | 0 | DIRECT |
50447,50465 50447 - Translation proteins 50465 - EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | DIRECT |
100920,100934 100920 - Heat shock protein 70kD (HSP70), peptide-binding domain 100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | DIRECT |
49265,48726 49265 - Fibronectin type III 48726 - Immunoglobulin | 0 | DIRECT |
48592,54849 48592 - GroEL equatorial domain-like 54849 - GroEL-intermediate domain like | 0 | DIRECT |
55753,55753 55753 - Actin depolymerizing proteins 55753 - Actin depolymerizing proteins | 0 | DIRECT |
57903,57903 57903 - FYVE/PHD zinc finger 57903 - FYVE/PHD zinc finger | 0 | DIRECT |
47220,47220 47220 - alpha-catenin/vinculin-like 47220 - alpha-catenin/vinculin-like | 0 | DIRECT |
49899,49899 49899 - Concanavalin A-like lectins/glucanases 49899 - Concanavalin A-like lectins/glucanases | 0 | DIRECT |
53223,51735 53223 - Aminoacid dehydrogenase-like, N-terminal domain 51735 - NAD(P)-binding Rossmann-fold domains | 0 | DIRECT |
53067,100920 53067 - Actin-like ATPase domain 100920 - Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | DIRECT |
51735,48179 51735 - NAD(P)-binding Rossmann-fold domains 48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like | 0 | DIRECT |
81301,81631 81301 - Nucleotidyltransferase 81631 - PAP/OAS1 substrate-binding domain | 0 | DIRECT |
50156,50044 50156 - PDZ domain-like 50044 - SH3-domain | 0 | DIRECT |
57625,57625 57625 - Invertebrate chitin-binding proteins 57625 - Invertebrate chitin-binding proteins | 0 | DIRECT |
48371,56112 48371 - ARM repeat 56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
54534,48452 54534 - FKBP-like 48452 - TPR-like | 0 | DIRECT |
54849,52029 54849 - GroEL-intermediate domain like 52029 - GroEL apical domain-like | 0 | DIRECT |
49899,57196 49899 - Concanavalin A-like lectins/glucanases 57196 - EGF/Laminin | 0 | DIRECT |
47459,55785 47459 - HLH, helix-loop-helix DNA-binding domain 55785 - PYP-like sensor domain (PAS domain) | 0 | DIRECT |
49265,49265 49265 - Fibronectin type III 49265 - Fibronectin type III | 0 | DIRECT |
47459,158457 47459 - HLH, helix-loop-helix DNA-binding domain 158457 - Orange domain-like | 0 | DIRECT |
55550,50044 55550 - SH2 domain 50044 - SH3-domain | 0 | DIRECT |
49854,49854 49854 - Spermadhesin, CUB domain 49854 - Spermadhesin, CUB domain | 0 | DIRECT |
55945,55945 55945 - TATA-box binding protein-like 55945 - TATA-box binding protein-like | 0 | DIRECT |
48065,50729 48065 - DBL homology domain (DH-domain) 50729 - PH domain-like | 0 | DIRECT |
52113,52113 52113 - BRCT domain 52113 - BRCT domain | 0 | DIRECT |
52540,50447 52540 - P-loop containing nucleoside triphosphate hydrolases 50447 - Translation proteins | 0 | DIRECT |
75632,46785 75632 - Cullin homology domain 46785 - "Winged helix" DNA-binding domain | 0 | DIRECT |
63748,63748 63748 - Tudor/PWWP/MBT 63748 - Tudor/PWWP/MBT | 0 | DIRECT |
54928,54928 54928 - RNA-binding domain, RBD 54928 - RNA-binding domain, RBD | 0 | DIRECT |
74788,75632 74788 - Cullin repeat-like 75632 - Cullin homology domain | 0 | DIRECT |
52058,52058 52058 - L domain-like 52058 - L domain-like | 0 | DIRECT |
48452,48452 48452 - TPR-like 48452 - TPR-like | 0 | DIRECT |
57424,57424 57424 - LDL receptor-like module 57424 - LDL receptor-like module | 0 | DIRECT |
82895,82895 82895 - TSP-1 type 1 repeat 82895 - TSP-1 type 1 repeat | 0 | DIRECT |
48726,48726 48726 - Immunoglobulin 48726 - Immunoglobulin | 0 | DIRECT |
47203,47203 47203 - Acyl-CoA dehydrogenase C-terminal domain-like 47203 - Acyl-CoA dehydrogenase C-terminal domain-like | 0 | DIRECT |
50044,50044 50044 - SH3-domain 50044 - SH3-domain | 0 | DIRECT |
57196,57196 57196 - EGF/Laminin 57196 - EGF/Laminin | 0 | DIRECT |
57184,57196 57184 - Growth factor receptor domain 57196 - EGF/Laminin | 0 | DIRECT |
81660,56784 81660 - Metal cation-transporting ATPase, ATP-binding domain N 56784 - HAD-like | 0 | DIRECT |
50044,55550 50044 - SH3-domain 55550 - SH2 domain | 0 | DIRECT |
52540,52540 52540 - P-loop containing nucleoside triphosphate hydrolases 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
47895,52540 47895 - Transducin (alpha subunit), insertion domain 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
49562,48371 49562 - C2 domain (Calcium/lipid-binding domain, CaLB) 48371 - ARM repeat | 0 | DIRECT |
52374,47323 52374 - Nucleotidylyl transferase 47323 - Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0 | DIRECT |
47473,47473 47473 - EF-hand 47473 - EF-hand | 0 | DIRECT |
81296,81296 81296 - E set domains 81296 - E set domains | 0 | DIRECT |
50156,50156 50156 - PDZ domain-like 50156 - PDZ domain-like | 0 | DIRECT |
47413,46689 47413 - lambda repressor-like DNA-binding domains 46689 - Homeodomain-like | 0 | DIRECT |
46785,46785 46785 - "Winged helix" DNA-binding domain 46785 - "Winged helix" DNA-binding domain | 0 | DIRECT |
54791,54791 54791 - Eukaryotic type KH-domain (KH-domain type I) 54791 - Eukaryotic type KH-domain (KH-domain type I) | 0 | DIRECT |
56784,81665 56784 - HAD-like 81665 - Calcium ATPase, transmembrane domain M | 0 | DIRECT |
50978,50978 50978 - WD40 repeat-like 50978 - WD40 repeat-like | 0 | DIRECT |
51045,51045 51045 - WW domain 51045 - WW domain | 0 | DIRECT |
52540,48019 52540 - P-loop containing nucleoside triphosphate hydrolases 48019 - post-AAA+ oligomerization domain-like | 0 | DIRECT |
47031,50729 47031 - Second domain of FERM 50729 - PH domain-like | 0 | DIRECT |
48425,50729 48425 - Sec7 domain 50729 - PH domain-like | 0 | DIRECT |
52490,55307 52490 - Tubulin nucleotide-binding domain-like 55307 - Tubulin C-terminal domain-like | 0 | DIRECT |
52440,56059 52440 - PreATP-grasp domain 56059 - Glutathione synthetase ATP-binding domain-like | 0 | DIRECT |
57716,48508 57716 - Glucocorticoid receptor-like (DNA-binding domain) 48508 - Nuclear receptor ligand-binding domain | 0 | DIRECT |
57196,49854 57196 - EGF/Laminin 49854 - Spermadhesin, CUB domain | 0 | DIRECT |
54768,54768 54768 - dsRNA-binding domain-like 54768 - dsRNA-binding domain-like | 0 | DIRECT |
63737,55486 63737 - Leukotriene A4 hydrolase N-terminal domain 55486 - Metalloproteases ("zincins"), catalytic domain | 0 | DIRECT |
48726,49265 48726 - Immunoglobulin 49265 - Fibronectin type III | 0 | DIRECT |
46785,54928 46785 - "Winged helix" DNA-binding domain 54928 - RNA-binding domain, RBD | 0 | DIRECT |
81383,52047 81383 - F-box domain 52047 - RNI-like | 0 | DIRECT |
54236,54236 54236 - Ubiquitin-like 54236 - Ubiquitin-like | 0 | DIRECT |
57716,57716 57716 - Glucocorticoid receptor-like (DNA-binding domain) 57716 - Glucocorticoid receptor-like (DNA-binding domain) | 0 | DIRECT |
51206,51206 51206 - cAMP-binding domain-like 51206 - cAMP-binding domain-like | 0 | DIRECT |
57667,57667 57667 - beta-beta-alpha zinc fingers 57667 - beta-beta-alpha zinc fingers | 0.2523 | INHERITED FROM: region of integument || segment || postalar bristle || adult integumentary system || prescutum || adult thoracic segment || appendage || thorax || adult thorax || organism subdivision || organ system || organ system subdivision || adult tagma || embryonic ganglion mother cell || integumentary system || adult || adult mesothoracic segment || tagma || adult segment || thoracic segment |
47954,47954 47954 - Cyclin-like 47954 - Cyclin-like | 0.8813 | INHERITED FROM: morphogenetic furrow |
Supra-domain (Duplex) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
57716,46689 57716 - Glucocorticoid receptor-like (DNA-binding domain) 46689 - Homeodomain-like | 0 | Direct |
101912,103575 101912 - Sema domain 103575 - Plexin repeat | 0 | Direct |
57196,49899 57196 - EGF/Laminin 49899 - Concanavalin A-like lectins/glucanases | 0 | Direct |
49313,49313 49313 - Cadherin-like 49313 - Cadherin-like | 0 | Direct |
52540,140990 52540 - P-loop containing nucleoside triphosphate hydrolases 140990 - FtsH protease domain-like | 0 | Direct |
47769,47769 47769 - SAM/Pointed domain 47769 - SAM/Pointed domain | 0 | Direct |
57903,47370 57903 - FYVE/PHD zinc finger 47370 - Bromodomain | 0 | Direct |
46966,46966 46966 - Spectrin repeat 46966 - Spectrin repeat | 0 | Direct |
55550,158235 55550 - SH2 domain 158235 - SOCS box-like | 0 | Direct |
57535,57535 57535 - Complement control module/SCR domain 57535 - Complement control module/SCR domain | 0 | Direct |
52799,52799 52799 - (Phosphotyrosine protein) phosphatases II 52799 - (Phosphotyrosine protein) phosphatases II | 0 | Direct |
52058,48726 52058 - L domain-like 48726 - Immunoglobulin | 0 | Direct |
101690,53098 101690 - PAZ domain 53098 - Ribonuclease H-like | 0 | Direct |
56645,47203 56645 - Acyl-CoA dehydrogenase NM domain-like 47203 - Acyl-CoA dehydrogenase C-terminal domain-like | 0 | Direct |
49562,49562 49562 - C2 domain (Calcium/lipid-binding domain, CaLB) 49562 - C2 domain (Calcium/lipid-binding domain, CaLB) | 0 | Direct |
57196,57184 57196 - EGF/Laminin 57184 - Growth factor receptor domain | 0 | Direct |
49417,81296 49417 - p53-like transcription factors 81296 - E set domains | 0 | Direct |
48403,48403 48403 - Ankyrin repeat 48403 - Ankyrin repeat | 0 | Direct |
50044,52540 50044 - SH3-domain 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
53067,53067 53067 - Actin-like ATPase domain 53067 - Actin-like ATPase domain | 0 | Direct |
55550,56112 55550 - SH2 domain 56112 - Protein kinase-like (PK-like) | 0 | Direct |
52833,52833 52833 - Thioredoxin-like 52833 - Thioredoxin-like | 0 | Direct |
54236,47031 54236 - Ubiquitin-like 47031 - Second domain of FERM | 0 | Direct |
57184,57184 57184 - Growth factor receptor domain 57184 - Growth factor receptor domain | 0 | Direct |
52777,52777 52777 - CoA-dependent acyltransferases 52777 - CoA-dependent acyltransferases | 0 | Direct |
57889,57889 57889 - Cysteine-rich domain 57889 - Cysteine-rich domain | 0 | Direct |
51905,54373 51905 - FAD/NAD(P)-binding domain 54373 - FAD-linked reductases, C-terminal domain | 0 | Direct |
63712,90112 63712 - Nicotinic receptor ligand binding domain-like 90112 - Neurotransmitter-gated ion-channel transmembrane pore | 0 | Direct |
50447,50465 50447 - Translation proteins 50465 - EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | Direct |
100920,100934 100920 - Heat shock protein 70kD (HSP70), peptide-binding domain 100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | Direct |
49265,48726 49265 - Fibronectin type III 48726 - Immunoglobulin | 0 | Direct |
48592,54849 48592 - GroEL equatorial domain-like 54849 - GroEL-intermediate domain like | 0 | Direct |
55753,55753 55753 - Actin depolymerizing proteins 55753 - Actin depolymerizing proteins | 0 | Direct |
57903,57903 57903 - FYVE/PHD zinc finger 57903 - FYVE/PHD zinc finger | 0 | Direct |
47220,47220 47220 - alpha-catenin/vinculin-like 47220 - alpha-catenin/vinculin-like | 0 | Direct |
49899,49899 49899 - Concanavalin A-like lectins/glucanases 49899 - Concanavalin A-like lectins/glucanases | 0 | Direct |
53223,51735 53223 - Aminoacid dehydrogenase-like, N-terminal domain 51735 - NAD(P)-binding Rossmann-fold domains | 0 | Direct |
53067,100920 53067 - Actin-like ATPase domain 100920 - Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | Direct |
51735,48179 51735 - NAD(P)-binding Rossmann-fold domains 48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like | 0 | Direct |
81301,81631 81301 - Nucleotidyltransferase 81631 - PAP/OAS1 substrate-binding domain | 0 | Direct |
50156,50044 50156 - PDZ domain-like 50044 - SH3-domain | 0 | Direct |
57625,57625 57625 - Invertebrate chitin-binding proteins 57625 - Invertebrate chitin-binding proteins | 0 | Direct |
48371,56112 48371 - ARM repeat 56112 - Protein kinase-like (PK-like) | 0 | Direct |
54534,48452 54534 - FKBP-like 48452 - TPR-like | 0 | Direct |
54849,52029 54849 - GroEL-intermediate domain like 52029 - GroEL apical domain-like | 0 | Direct |
49899,57196 49899 - Concanavalin A-like lectins/glucanases 57196 - EGF/Laminin | 0 | Direct |
47459,55785 47459 - HLH, helix-loop-helix DNA-binding domain 55785 - PYP-like sensor domain (PAS domain) | 0 | Direct |
49265,49265 49265 - Fibronectin type III 49265 - Fibronectin type III | 0 | Direct |
47459,158457 47459 - HLH, helix-loop-helix DNA-binding domain 158457 - Orange domain-like | 0 | Direct |
55550,50044 55550 - SH2 domain 50044 - SH3-domain | 0 | Direct |
49854,49854 49854 - Spermadhesin, CUB domain 49854 - Spermadhesin, CUB domain | 0 | Direct |
55945,55945 55945 - TATA-box binding protein-like 55945 - TATA-box binding protein-like | 0 | Direct |
48065,50729 48065 - DBL homology domain (DH-domain) 50729 - PH domain-like | 0 | Direct |
52113,52113 52113 - BRCT domain 52113 - BRCT domain | 0 | Direct |
52540,50447 52540 - P-loop containing nucleoside triphosphate hydrolases 50447 - Translation proteins | 0 | Direct |
75632,46785 75632 - Cullin homology domain 46785 - "Winged helix" DNA-binding domain | 0 | Direct |
63748,63748 63748 - Tudor/PWWP/MBT 63748 - Tudor/PWWP/MBT | 0 | Direct |
54928,54928 54928 - RNA-binding domain, RBD 54928 - RNA-binding domain, RBD | 0 | Direct |
74788,75632 74788 - Cullin repeat-like 75632 - Cullin homology domain | 0 | Direct |
52058,52058 52058 - L domain-like 52058 - L domain-like | 0 | Direct |
48452,48452 48452 - TPR-like 48452 - TPR-like | 0 | Direct |
57424,57424 57424 - LDL receptor-like module 57424 - LDL receptor-like module | 0 | Direct |
82895,82895 82895 - TSP-1 type 1 repeat 82895 - TSP-1 type 1 repeat | 0 | Direct |
48726,48726 48726 - Immunoglobulin 48726 - Immunoglobulin | 0 | Direct |
47203,47203 47203 - Acyl-CoA dehydrogenase C-terminal domain-like 47203 - Acyl-CoA dehydrogenase C-terminal domain-like | 0 | Direct |
50044,50044 50044 - SH3-domain 50044 - SH3-domain | 0 | Direct |
57196,57196 57196 - EGF/Laminin 57196 - EGF/Laminin | 0 | Direct |
57184,57196 57184 - Growth factor receptor domain 57196 - EGF/Laminin | 0 | Direct |
81660,56784 81660 - Metal cation-transporting ATPase, ATP-binding domain N 56784 - HAD-like | 0 | Direct |
50044,55550 50044 - SH3-domain 55550 - SH2 domain | 0 | Direct |
52540,52540 52540 - P-loop containing nucleoside triphosphate hydrolases 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
47895,52540 47895 - Transducin (alpha subunit), insertion domain 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
49562,48371 49562 - C2 domain (Calcium/lipid-binding domain, CaLB) 48371 - ARM repeat | 0 | Direct |
52374,47323 52374 - Nucleotidylyl transferase 47323 - Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0 | Direct |
47473,47473 47473 - EF-hand 47473 - EF-hand | 0 | Direct |
81296,81296 81296 - E set domains 81296 - E set domains | 0 | Direct |
50156,50156 50156 - PDZ domain-like 50156 - PDZ domain-like | 0 | Direct |
47413,46689 47413 - lambda repressor-like DNA-binding domains 46689 - Homeodomain-like | 0 | Direct |
46785,46785 46785 - "Winged helix" DNA-binding domain 46785 - "Winged helix" DNA-binding domain | 0 | Direct |
54791,54791 54791 - Eukaryotic type KH-domain (KH-domain type I) 54791 - Eukaryotic type KH-domain (KH-domain type I) | 0 | Direct |
56784,81665 56784 - HAD-like 81665 - Calcium ATPase, transmembrane domain M | 0 | Direct |
50978,50978 50978 - WD40 repeat-like 50978 - WD40 repeat-like | 0 | Direct |
51045,51045 51045 - WW domain 51045 - WW domain | 0 | Direct |
52540,48019 52540 - P-loop containing nucleoside triphosphate hydrolases 48019 - post-AAA+ oligomerization domain-like | 0 | Direct |
47031,50729 47031 - Second domain of FERM 50729 - PH domain-like | 0 | Direct |
48425,50729 48425 - Sec7 domain 50729 - PH domain-like | 0 | Direct |
52490,55307 52490 - Tubulin nucleotide-binding domain-like 55307 - Tubulin C-terminal domain-like | 0 | Direct |
52440,56059 52440 - PreATP-grasp domain 56059 - Glutathione synthetase ATP-binding domain-like | 0 | Direct |
57716,48508 57716 - Glucocorticoid receptor-like (DNA-binding domain) 48508 - Nuclear receptor ligand-binding domain | 0 | Direct |
57196,49854 57196 - EGF/Laminin 49854 - Spermadhesin, CUB domain | 0 | Direct |
54768,54768 54768 - dsRNA-binding domain-like 54768 - dsRNA-binding domain-like | 0 | Direct |
63737,55486 63737 - Leukotriene A4 hydrolase N-terminal domain 55486 - Metalloproteases ("zincins"), catalytic domain | 0 | Direct |
48726,49265 48726 - Immunoglobulin 49265 - Fibronectin type III | 0 | Direct |
46785,54928 46785 - "Winged helix" DNA-binding domain 54928 - RNA-binding domain, RBD | 0 | Direct |
81383,52047 81383 - F-box domain 52047 - RNI-like | 0 | Direct |
54236,54236 54236 - Ubiquitin-like 54236 - Ubiquitin-like | 0 | Direct |
57716,57716 57716 - Glucocorticoid receptor-like (DNA-binding domain) 57716 - Glucocorticoid receptor-like (DNA-binding domain) | 0 | Direct |
51206,51206 51206 - cAMP-binding domain-like 51206 - cAMP-binding domain-like | 0 | Direct |
57667,57667 57667 - beta-beta-alpha zinc fingers 57667 - beta-beta-alpha zinc fingers | 0.2523 | Inherited |
47954,47954 47954 - Cyclin-like 47954 - Cyclin-like | 0.8813 | Inherited |
(show details)
Supra-domains annotated to this FA term (Not in SPFA)
Highlighted in gray are those with FDR>0.001
Supra-domain (Triple) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
53067,53067,100920 53067 - Actin-like ATPase domain 53067 - Actin-like ATPase domain 100920 - Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | DIRECT |
49265,48726,48726 49265 - Fibronectin type III 48726 - Immunoglobulin 48726 - Immunoglobulin | 0 | DIRECT |
49562,48371,56112 49562 - C2 domain (Calcium/lipid-binding domain, CaLB) 48371 - ARM repeat 56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
56645,47203,47203 56645 - Acyl-CoA dehydrogenase NM domain-like 47203 - Acyl-CoA dehydrogenase C-terminal domain-like 47203 - Acyl-CoA dehydrogenase C-terminal domain-like | 0 | DIRECT |
52540,52540,52540 52540 - P-loop containing nucleoside triphosphate hydrolases 52540 - P-loop containing nucleoside triphosphate hydrolases 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
48726,48726,49265 48726 - Immunoglobulin 48726 - Immunoglobulin 49265 - Fibronectin type III | 0 | DIRECT |
57535,57535,57535 57535 - Complement control module/SCR domain 57535 - Complement control module/SCR domain 57535 - Complement control module/SCR domain | 0 | DIRECT |
57196,49899,49899 57196 - EGF/Laminin 49899 - Concanavalin A-like lectins/glucanases 49899 - Concanavalin A-like lectins/glucanases | 0 | DIRECT |
49313,49313,49313 49313 - Cadherin-like 49313 - Cadherin-like 49313 - Cadherin-like | 0 | DIRECT |
57716,57716,57716 57716 - Glucocorticoid receptor-like (DNA-binding domain) 57716 - Glucocorticoid receptor-like (DNA-binding domain) 57716 - Glucocorticoid receptor-like (DNA-binding domain) | 0 | DIRECT |
74788,75632,46785 74788 - Cullin repeat-like 75632 - Cullin homology domain 46785 - "Winged helix" DNA-binding domain | 0 | DIRECT |
57196,57196,57196 57196 - EGF/Laminin 57196 - EGF/Laminin 57196 - EGF/Laminin | 0 | DIRECT |
48726,48726,48726 48726 - Immunoglobulin 48726 - Immunoglobulin 48726 - Immunoglobulin | 0 | DIRECT |
46966,46966,46966 46966 - Spectrin repeat 46966 - Spectrin repeat 46966 - Spectrin repeat | 0 | DIRECT |
81660,56784,81665 81660 - Metal cation-transporting ATPase, ATP-binding domain N 56784 - HAD-like 81665 - Calcium ATPase, transmembrane domain M | 0 | DIRECT |
52833,52833,52833 52833 - Thioredoxin-like 52833 - Thioredoxin-like 52833 - Thioredoxin-like | 0 | DIRECT |
48592,54849,52029 48592 - GroEL equatorial domain-like 54849 - GroEL-intermediate domain like 52029 - GroEL apical domain-like | 0 | DIRECT |
57667,57667,57667 57667 - beta-beta-alpha zinc fingers 57667 - beta-beta-alpha zinc fingers 57667 - beta-beta-alpha zinc fingers | 0 | DIRECT |
57625,57625,57625 57625 - Invertebrate chitin-binding proteins 57625 - Invertebrate chitin-binding proteins 57625 - Invertebrate chitin-binding proteins | 0 | DIRECT |
57184,57196,57196 57184 - Growth factor receptor domain 57196 - EGF/Laminin 57196 - EGF/Laminin | 0 | DIRECT |
52058,52058,52058 52058 - L domain-like 52058 - L domain-like 52058 - L domain-like | 0 | DIRECT |
57424,57424,57424 57424 - LDL receptor-like module 57424 - LDL receptor-like module 57424 - LDL receptor-like module | 0 | DIRECT |
57196,57196,57184 57196 - EGF/Laminin 57196 - EGF/Laminin 57184 - Growth factor receptor domain | 0 | DIRECT |
81296,81296,81296 81296 - E set domains 81296 - E set domains 81296 - E set domains | 0 | DIRECT |
57196,57184,57196 57196 - EGF/Laminin 57184 - Growth factor receptor domain 57196 - EGF/Laminin | 0 | DIRECT |
52540,50447,50465 52540 - P-loop containing nucleoside triphosphate hydrolases 50447 - Translation proteins 50465 - EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | DIRECT |
54236,47031,50729 54236 - Ubiquitin-like 47031 - Second domain of FERM 50729 - PH domain-like | 0 | DIRECT |
49899,49899,49899 49899 - Concanavalin A-like lectins/glucanases 49899 - Concanavalin A-like lectins/glucanases 49899 - Concanavalin A-like lectins/glucanases | 0 | DIRECT |
53067,100920,100934 53067 - Actin-like ATPase domain 100920 - Heat shock protein 70kD (HSP70), peptide-binding domain 100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | DIRECT |
48452,48452,48452 48452 - TPR-like 48452 - TPR-like 48452 - TPR-like | 0 | DIRECT |
50156,50044,52540 50156 - PDZ domain-like 50044 - SH3-domain 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
Supra-domain (Triple) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
53067,53067,100920 53067 - Actin-like ATPase domain 53067 - Actin-like ATPase domain 100920 - Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | Direct |
49265,48726,48726 49265 - Fibronectin type III 48726 - Immunoglobulin 48726 - Immunoglobulin | 0 | Direct |
49562,48371,56112 49562 - C2 domain (Calcium/lipid-binding domain, CaLB) 48371 - ARM repeat 56112 - Protein kinase-like (PK-like) | 0 | Direct |
56645,47203,47203 56645 - Acyl-CoA dehydrogenase NM domain-like 47203 - Acyl-CoA dehydrogenase C-terminal domain-like 47203 - Acyl-CoA dehydrogenase C-terminal domain-like | 0 | Direct |
52540,52540,52540 52540 - P-loop containing nucleoside triphosphate hydrolases 52540 - P-loop containing nucleoside triphosphate hydrolases 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
48726,48726,49265 48726 - Immunoglobulin 48726 - Immunoglobulin 49265 - Fibronectin type III | 0 | Direct |
57535,57535,57535 57535 - Complement control module/SCR domain 57535 - Complement control module/SCR domain 57535 - Complement control module/SCR domain | 0 | Direct |
57196,49899,49899 57196 - EGF/Laminin 49899 - Concanavalin A-like lectins/glucanases 49899 - Concanavalin A-like lectins/glucanases | 0 | Direct |
49313,49313,49313 49313 - Cadherin-like 49313 - Cadherin-like 49313 - Cadherin-like | 0 | Direct |
57716,57716,57716 57716 - Glucocorticoid receptor-like (DNA-binding domain) 57716 - Glucocorticoid receptor-like (DNA-binding domain) 57716 - Glucocorticoid receptor-like (DNA-binding domain) | 0 | Direct |
74788,75632,46785 74788 - Cullin repeat-like 75632 - Cullin homology domain 46785 - "Winged helix" DNA-binding domain | 0 | Direct |
57196,57196,57196 57196 - EGF/Laminin 57196 - EGF/Laminin 57196 - EGF/Laminin | 0 | Direct |
48726,48726,48726 48726 - Immunoglobulin 48726 - Immunoglobulin 48726 - Immunoglobulin | 0 | Direct |
46966,46966,46966 46966 - Spectrin repeat 46966 - Spectrin repeat 46966 - Spectrin repeat | 0 | Direct |
81660,56784,81665 81660 - Metal cation-transporting ATPase, ATP-binding domain N 56784 - HAD-like 81665 - Calcium ATPase, transmembrane domain M | 0 | Direct |
52833,52833,52833 52833 - Thioredoxin-like 52833 - Thioredoxin-like 52833 - Thioredoxin-like | 0 | Direct |
48592,54849,52029 48592 - GroEL equatorial domain-like 54849 - GroEL-intermediate domain like 52029 - GroEL apical domain-like | 0 | Direct |
57667,57667,57667 57667 - beta-beta-alpha zinc fingers 57667 - beta-beta-alpha zinc fingers 57667 - beta-beta-alpha zinc fingers | 0 | Direct |
57625,57625,57625 57625 - Invertebrate chitin-binding proteins 57625 - Invertebrate chitin-binding proteins 57625 - Invertebrate chitin-binding proteins | 0 | Direct |
57184,57196,57196 57184 - Growth factor receptor domain 57196 - EGF/Laminin 57196 - EGF/Laminin | 0 | Direct |
52058,52058,52058 52058 - L domain-like 52058 - L domain-like 52058 - L domain-like | 0 | Direct |
57424,57424,57424 57424 - LDL receptor-like module 57424 - LDL receptor-like module 57424 - LDL receptor-like module | 0 | Direct |
57196,57196,57184 57196 - EGF/Laminin 57196 - EGF/Laminin 57184 - Growth factor receptor domain | 0 | Direct |
81296,81296,81296 81296 - E set domains 81296 - E set domains 81296 - E set domains | 0 | Direct |
57196,57184,57196 57196 - EGF/Laminin 57184 - Growth factor receptor domain 57196 - EGF/Laminin | 0 | Direct |
52540,50447,50465 52540 - P-loop containing nucleoside triphosphate hydrolases 50447 - Translation proteins 50465 - EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | Direct |
54236,47031,50729 54236 - Ubiquitin-like 47031 - Second domain of FERM 50729 - PH domain-like | 0 | Direct |
49899,49899,49899 49899 - Concanavalin A-like lectins/glucanases 49899 - Concanavalin A-like lectins/glucanases 49899 - Concanavalin A-like lectins/glucanases | 0 | Direct |
53067,100920,100934 53067 - Actin-like ATPase domain 100920 - Heat shock protein 70kD (HSP70), peptide-binding domain 100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | Direct |
48452,48452,48452 48452 - TPR-like 48452 - TPR-like 48452 - TPR-like | 0 | Direct |
50156,50044,52540 50156 - PDZ domain-like 50044 - SH3-domain 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
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A presence/absence matrix is generated using protein domains and supradomains
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