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Fly Phenotype (FP): increased mortality during development

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Root: FP Hierarchy (fly phenotype from FlyBase controlled vocabulary with sub-ontology "phenotypic class")

Shortest distance to current term (+ for parents, - for children) FP term [FP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + 3:   phenotypic class [FBcv:0000347] <4>
+ + 2:   phenotype [FBcv:0001347] <62>(175|208) (176|81|29)
+ 1:   increased mortality [FBcv:0002004] <2>(55|72) (55|19|7)
0:   increased mortality during development [FBcv:0002019] <6>(42|60) (42|14|6)
- 1:   some die during P-stage [FBcv:0002020] <4>(2|4) (2|2|1)
- 1:   some die during larval stage [FBcv:0002023] <4>(2|2) (2|1|0)
- 1:   lethal [FBcv:0000351] <2>(32|51) (32|9|4)
- 1:   partially lethal [FBcv:0002015] <2>(1|2) (1|1|0)
- 1:   some die during embryonic stage [FBcv:0002041] <1>(3|3) (3|0|2)
- 1:   some die during immature adult stage [FBcv:0002051] <1>(0|0) (0|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
RBP11-like subunits of RNA polymerase0Direct
Tetrahydrobiopterin biosynthesis enzymes-like0Direct
Terpenoid synthases0Direct
Cytokine0Direct
Nop domain0Direct
PIN domain-like0Direct
ACP-like0Direct
DEK C-terminal domain0Direct
S15/NS1 RNA-binding domain0Direct
RNase III domain-like0Direct
ARID-like0Direct
Smc hinge domain0Direct
Zinc beta-ribbon0Direct
SAND domain-like0Direct
KA1-like0Direct
Ribonuclease PH domain 2-like0Direct
HR1 repeat0Direct
E2F-DP heterodimerization region0Direct
Aromatic aminoacid monoxygenases, catalytic and oligomerization domains0Direct
Isocitrate/Isopropylmalate dehydrogenase-like0Direct
ACT-like0Direct
Formin homology 2 domain (FH2 domain)0Direct
lambda repressor-like DNA-binding domains0Direct
B-box zinc-binding domain0Direct
Subtilisin-like0Direct
SMAD/FHA domain0Direct
PriA/YqbF domain0Direct
Multidrug efflux transporter AcrB transmembrane domain0Direct
Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor0Direct
SMAD MH1 domain0Direct
GINS helical bundle-like0Direct
Homeodomain-like0.0000001504Direct
SNARE fusion complex0.0009774Direct
Nuclear receptor ligand-binding domain0.001043Inherited
beta-sandwich domain of Sec23/240.006824Inherited
Spectrin repeat0.01106Inherited
Snake toxin-like0.03348Inherited
RNA-binding domain, RBD0.04288Inherited
EGF/Laminin0.1162Inherited
Protein kinase-like (PK-like)0.1302Inherited
ARM repeat0.2341Inherited
Leucine zipper domain0.297Inherited


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Family

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SCOP termFDR (all)Annotation (direct or inherited)
Integrin domains0Direct
Translational machinery components0Direct
SMAD MH1 domain0Direct
FHA domain0Direct
Fibroblast growth factors (FGF)0Direct
PAPS sulfotransferase0Direct
Cell cycle transcription factor e2f-dp0Direct
Group II chaperonin (CCT, TRIC), intermediate domain0Direct
Rel/Dorsal transcription factors, DNA-binding domain0Direct
Nop domain0Direct
Acyl-carrier protein (ACP)0Direct
RUNT domain0Direct
Meta-cation ATPase, catalytic domain P0Direct
beta-CASP RNA-metabolising hydrolases0Direct
Inositol polyphosphate kinase (IPK)0Direct
MBT repeat0Direct
Chromo barrel domain0Direct
Transcriptional factor domain0Direct
RNase III catalytic domain-like0Direct
Diap1 N-terninal region-like0Direct
HR1 repeat0Direct
Class I glutamine amidotransferases (GAT)0Direct
DEK C-terminal domain0Direct
Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor0Direct
Anticodon-binding domain of Class II aaRS0Direct
Smc hinge domain0Direct
Eps15 homology domain (EH domain)0Direct
Ubiquitin activating enzymes (UBA)0Direct
Extracellular domain of cell surface receptors0Direct
Paired domain0Direct
Single strand DNA-binding domain, SSB0Direct
Aromatic aminoacid monoxygenases, catalytic and oligomerization domains0Direct
POU-specific domain0Direct
Formin homology 2 domain (FH2 domain)0Direct
NHL repeat0Direct
a tRNA synthase domain0Direct
Ribonuclease PH domain 2-like0Direct
ARID domain0Direct
Dimeric isocitrate & isopropylmalate dehydrogenases0Direct
Multidrug efflux transporter AcrB transmembrane domain0Direct
Subtilases0Direct
SMAD domain0Direct
Laminin-type module0Direct
Isoprenyl diphosphate synthases0Direct
Dachshund-homology domain0Direct
Ribonuclease PH domain 1-like0Direct
B-box zinc-binding domain0Direct
Homeodomain0.0000001996Direct
Nuclear receptor0.0003824Direct
Nuclear receptor ligand-binding domain0.001193Inherited
Motor proteins0.005717Inherited
Spectrin repeat0.01067Inherited
Canonical RBD0.07471Inherited
Erythroid transcription factor GATA-10.08924Inherited
Protein kinases, catalytic subunit0.1603Inherited
Leucine zipper domain0.2547Inherited
EGF-type module0.2781Inherited
Zf-UBP0.3187Inherited
Histone lysine methyltransferases0.4371Inherited
Pleckstrin-homology domain (PH domain)0.6442Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Isocitrate/Isopropylmalate dehydrogenase-like0Direct
B-box zinc-binding domain0Direct
lambda repressor-like DNA-binding domains0Direct
PriA/YqbF domain0Direct
RBP11-like subunits of RNA polymerase0Direct
GINS helical bundle-like0Direct
SMAD MH1 domain0Direct
Cytokine0Direct
Nop domain0Direct
SMAD/FHA domain0Direct
SAND domain-like0Direct
Aromatic aminoacid monoxygenases, catalytic and oligomerization domains0Direct
ARID-like0Direct
Ribonuclease PH domain 2-like0Direct
PIN domain-like0Direct
HR1 repeat0Direct
ACP-like0Direct
Multidrug efflux transporter AcrB transmembrane domain0Direct
RNase III domain-like0Direct
Zinc beta-ribbon0Direct
Subtilisin-like0Direct
Tetrahydrobiopterin biosynthesis enzymes-like0Direct
ACT-like0Direct
DEK C-terminal domain0Direct
Formin homology 2 domain (FH2 domain)0Direct
Terpenoid synthases0Direct
KA1-like0Direct
S15/NS1 RNA-binding domain0Direct
Smc hinge domain0Direct
Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor0Direct
E2F-DP heterodimerization region0Direct
Homeodomain-like0.0000001087Direct
SNARE fusion complex0.0007385Direct
Nuclear receptor ligand-binding domain0.0007913Direct
beta-sandwich domain of Sec23/240.00549Inherited
Spectrin repeat0.009005Inherited
Snake toxin-like0.02793Inherited
RNA-binding domain, RBD0.03629Inherited
EGF/Laminin0.1014Inherited
Protein kinase-like (PK-like)0.1136Inherited
ARM repeat0.2077Inherited
Leucine zipper domain0.2688Inherited

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
47413,46689
  • 47413 - lambda repressor-like DNA-binding domains
  • 46689 - Homeodomain-like
  • 0Direct
    55550,56112
  • 55550 - SH2 domain
  • 56112 - Protein kinase-like (PK-like)
  • 0Direct
    46785,46785
  • 46785 - "Winged helix" DNA-binding domain
  • 46785 - "Winged helix" DNA-binding domain
  • 0Direct
    57196,49854
  • 57196 - EGF/Laminin
  • 49854 - Spermadhesin, CUB domain
  • 0Direct
    49417,81296
  • 49417 - p53-like transcription factors
  • 81296 - E set domains
  • 0Direct
    63748,63748
  • 63748 - Tudor/PWWP/MBT
  • 63748 - Tudor/PWWP/MBT
  • 0Direct
    52113,52113
  • 52113 - BRCT domain
  • 52113 - BRCT domain
  • 0Direct
    55021,56534
  • 55021 - ACT-like
  • 56534 - Aromatic aminoacid monoxygenases, catalytic and oligomerization domains
  • 0Direct
    46785,144074
  • 46785 - "Winged helix" DNA-binding domain
  • 144074 - E2F-DP heterodimerization region
  • 0Direct
    54211,55666
  • 54211 - Ribosomal protein S5 domain 2-like
  • 55666 - Ribonuclease PH domain 2-like
  • 0Direct
    57903,47370
  • 57903 - FYVE/PHD zinc finger
  • 47370 - Bromodomain
  • 0Direct
    46966,46966
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 0Direct
    50044,55550
  • 50044 - SH3-domain
  • 55550 - SH2 domain
  • 0.6506Inherited
    57850,57850
  • 57850 - RING/U-box
  • 57850 - RING/U-box
  • 0.7108Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    46966,46966,46966
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 0Direct
    57196,49899,49899
  • 57196 - EGF/Laminin
  • 49899 - Concanavalin A-like lectins/glucanases
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0Direct
    57850,57850,57850
  • 57850 - RING/U-box
  • 57850 - RING/U-box
  • 57850 - RING/U-box
  • 0Direct
    48452,48452,48452
  • 48452 - TPR-like
  • 48452 - TPR-like
  • 48452 - TPR-like
  • 0Direct
    49899,49899,49899
  • 49899 - Concanavalin A-like lectins/glucanases
  • 49899 - Concanavalin A-like lectins/glucanases
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0Direct
    57196,57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.4569Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
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